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  1. Article ; Online: Deriving iron contents from past and future Venus surface spectra with new high-temperature laboratory emissivity data.

    Helbert, J / Maturilli, A / Dyar, M D / Alemanno, G

    Science advances

    2021  Volume 7, Issue 3

    Abstract: In situ information on the surface composition of Venus is based on measurements of a small number of landing sites. In the laboratory, we measured the emissivity of a range of igneous rocks at temperatures up to 480°C. We show that high-temperature ... ...

    Abstract In situ information on the surface composition of Venus is based on measurements of a small number of landing sites. In the laboratory, we measured the emissivity of a range of igneous rocks at temperatures up to 480°C. We show that high-temperature laboratory spectra of basalts are consistent with the only existing multispectral data from the surface of Venus obtained by the photometers on the Venera 9 and 10 landers. We derive the FeO abundances for these landing sites of 12.2 and 9.5 weight %, respectively. From orbit, Venus' surface is only observable on the nightside through small spectral windows near 1 μm where the CO
    Language English
    Publishing date 2021-01-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2810933-8
    ISSN 2375-2548 ; 2375-2548
    ISSN (online) 2375-2548
    ISSN 2375-2548
    DOI 10.1126/sciadv.aba9428
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  2. Article ; Online: Use of a novel chyme reinfusion device during damage control surgery to improve nutritional status in a patient with a proximal ileostomy: A video vignette.

    Alemanno, Giovanni / Tirloni, Luca / Morabito, Antonino / Coletta, Riccardo / Prosperi, Paolo

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

    2022  Volume 24, Issue 10, Page(s) 1255–1256

    MeSH term(s) Humans ; Ileostomy ; Nutritional Status ; Gastrointestinal Contents
    Language English
    Publishing date 2022-06-03
    Publishing country England
    Document type Video-Audio Media ; Letter
    ZDB-ID 1440017-0
    ISSN 1463-1318 ; 1462-8910
    ISSN (online) 1463-1318
    ISSN 1462-8910
    DOI 10.1111/codi.16166
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  3. Article ; Online: Diagnostic and therapeutic role of laparoscopy in perforated peptic ulcer in the elderly patients.

    Giordano, Angela / Prosperi, P / Alemanno, G / Bergamini, C / Bruscino, A / Valeri, A

    Il Giornale di chirurgia

    2020  Volume 41, Issue 1, Page(s) 40–45

    Abstract: Aim: The purpose of this study is to analyze the outcome of elderly patients with perforated peptic ulcer comparing laparoscopic treatment versus open approach.: Methods: In our General and Emergency Surgery Unit in the last 3 years, 20 elderly ... ...

    Abstract Aim: The purpose of this study is to analyze the outcome of elderly patients with perforated peptic ulcer comparing laparoscopic treatment versus open approach.
    Methods: In our General and Emergency Surgery Unit in the last 3 years, 20 elderly patients with perforated peptic ulcer were performed. We considered elderly all patients over the age of 65 years (10 females and 10 males; the mean age was 75 years). 16 patients (80%) were submitted to laparoscopic repair with omentoplasty and 4 (20%) to open repair. The patients were classified using the Boye's score which influenced the choice of surgical treatment and the outcoEmergency Romame. The two groups were compared in terms of operative surgery times, complication rate, mortality and postoperative outcomes.
    Discussion: Perforated peptic ulcer is a common abdominal disease that is treated by surgery. The potential advantages of laparoscopy, both in terms of diagnosis and therapy, are clear and the major advantages may be observed in cases with peritonitis secondary as a perforated peptic ulcer where laparoscopy allows the confirmation of the diagnosis, the identification of the position of the ulcer and the repair. With the age the risks of comorbidities increases multidisease syndrome. Elderly patients suffer from frailty syndrome. All these factors make the elderly patient a major challenge for a laparoscopy treatment.
    Conclusion: The laparoscopic approach is an effective method for treatment of perforated peptic ulcer in the elderly with a great diagnostic and therapeutic role. Nowadays more prospective randomized studies are needed to evaluate the effectiveness of laparoscopic versus open repair.
    MeSH term(s) Aged ; Female ; Frail Elderly ; Humans ; Laparoscopy/adverse effects ; Male ; Operative Time ; Peptic Ulcer Perforation/classification ; Peptic Ulcer Perforation/complications ; Peptic Ulcer Perforation/diagnosis ; Peptic Ulcer Perforation/surgery ; Peritonitis/diagnosis ; Peritonitis/etiology ; Postoperative Complications ; Treatment Outcome
    Language English
    Publishing date 2020-02-09
    Publishing country Italy
    Document type Comparative Study ; Journal Article
    ZDB-ID 605974-0
    ISSN 1971-145X ; 0391-9005
    ISSN (online) 1971-145X
    ISSN 0391-9005
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  4. Article ; Online: Multiparametric imaging guided HDR interventional radiotherapy (brachytherapy) boost in localized prostate cancer: a multidisciplinary experience.

    Tagliaferri, L / Alemanno, G / Fionda, B / Alitto, A R / Frascino, V / Cellini, F / Lancellotta, V / Placidi, E / Morganti, A G / Kovács, G / Giordano, A / Manfredi, R / Valentini, V

    European review for medical and pharmacological sciences

    2023  Volume 27, Issue 9, Page(s) 4175–4184

    Abstract: Objective: The aim of this study was to report a monoinstitutional multidisciplinary experience about the use of multiparametric imaging to identify the areas with higher risk of relapse in localized prostate cancer, with the purpose of allowing a ... ...

    Abstract Objective: The aim of this study was to report a monoinstitutional multidisciplinary experience about the use of multiparametric imaging to identify the areas with higher risk of relapse in localized prostate cancer, with the purpose of allowing a biologically planned target dose escalation.
    Patients and methods: We performed a retrospective evaluation of patients diagnosed with prostate cancer who received treatments at our Interventional Oncology Center with interstitial interventional radiotherapy from 2014 to 2022. Inclusion criteria were histologically confirmed localized prostate cancer; and National Comprehensive Cancer Network (NCCN) risk class unfavorable intermediate or high/very high risk. The diagnostic work-up included multiparametric Magnetic resonance imaging (MRI), multiparametric Transrectal ultrasound (TRUS), Positron Emission Tomography Computed Tomography (PET-CT) with choline or PSMA (or alternatively bone scan). All patients were assessed and received one treatment with interstitial high-dose-rate interventional radiotherapy (brachytherapy) delivering external beam radiotherapy (46 Gy). All procedures were performed using transrectal ultrasound guidance under general anesthesia and the prescribed doses were 10 Gy to the whole prostate, 12 Gy to the peripheral zone and 15 Gy to the areas at risk.
    Results: We report the data of 21 patients who were considered for the statistical analysis with a mean age of 62.5 years. The mean PSA nadir was 0.03 ng/ml (range 0-0.09). So far, no biochemical nor radiological recurrences have been recorded in our series. Regarding acute toxicity, the most commonly reported side effects were G1 urinary in 28.5% of patients and G2 urinary in 9.5%; all recorded acute toxicities resolved spontaneously.
    Conclusions: We present a real-life experience of biologically planned local dose escalation by interventional radiotherapy (brachytherapy) boost, followed by external beam radiotherapy in patients with intermediate unfavorable- or high/very high risk. The local control and the biochemical control rates are proved to be excellent and the toxicity profile tolerable.
    MeSH term(s) Male ; Humans ; Middle Aged ; Prostate-Specific Antigen ; Brachytherapy/methods ; Positron Emission Tomography Computed Tomography ; Retrospective Studies ; Neoplasm Recurrence, Local/etiology ; Prostatic Neoplasms/diagnostic imaging ; Prostatic Neoplasms/radiotherapy ; Radiotherapy Dosage
    Chemical Substances Prostate-Specific Antigen (EC 3.4.21.77)
    Language English
    Publishing date 2023-05-19
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 605550-3
    ISSN 2284-0729 ; 1128-3602 ; 0392-291X
    ISSN (online) 2284-0729
    ISSN 1128-3602 ; 0392-291X
    DOI 10.26355/eurrev_202305_32327
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The role of tibial nerve stimulation for enhanced postoperative recovery after colorectal surgery: a double-blind, parallel-group, randomized controlled trial.

    Martellucci, J / Sturiale, A / Alemanno, G / Bartolini, I / Pesi, B / Perna, F / Coratti, A / Prosperi, P / Valeri, A

    Techniques in coloproctology

    2020  Volume 25, Issue 2, Page(s) 195–203

    Abstract: Background: Postoperative ileus (POI) is the most common cause of prolonged hospital stay following abdominal surgery, despite an optimized enhanced recovery after surgery (ERAS) program. The aim of the study was to evaluate the role of postoperative ... ...

    Abstract Background: Postoperative ileus (POI) is the most common cause of prolonged hospital stay following abdominal surgery, despite an optimized enhanced recovery after surgery (ERAS) program. The aim of the study was to evaluate the role of postoperative transcutaneous electrical tibial nerve stimulation (TTNS) in the recovery of bowel function and in shortening hospital stay after colonic resection.
    Methods: Patients having elective laparoscopic colonic surgery within an ERAS program at our institution between June 2016 and June 2019 were enrolled and randomly assigned to a treatment protocol with TTNS or sham electrical stimulation. The primary endpoint was the time of recovery of gastrointestinal motility, measured as the first passage of stool. Secondary endpoints included: first passage of flatus, length of hospital stay, and complication rate related to the use of TTNS.
    Results: One hundred and seventy patients who had right hemicolectomy (median age 71 years (range 43-89 years); 47.5% women) and 170 patients who had left colectomy (median age 67 years range (37-92 years); 41.5% women) were enrolled. The only factor significantly affected by TTNS was time to first passage of flatus after right hemicolectomy (reduced from 46 to 33 h, p = 0.04). However, if only patients with low compliance to early oral nutrition (63 of 340; 18.5%) were considered, a statistically significant difference in time until first flatus (p < 0.01) and first bowel movement (p < 0.0001) and a shorter time until discharge (median 5 vs 7 days) were found in both left and right colectomies groups, respectively.
    Conclusions: TTNS may have a positive effect on gastrointestinal tract motility and recovery from POI after colorectal surgery in a selected group, who has low compliance with an ERAS program, without increasing the risk of complications.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Colectomy/adverse effects ; Colorectal Surgery ; Female ; Humans ; Ileus/etiology ; Ileus/therapy ; Laparoscopy/adverse effects ; Length of Stay ; Male ; Middle Aged ; Postoperative Complications/etiology ; Postoperative Period ; Recovery of Function ; Tibial Nerve ; Treatment Outcome
    Language English
    Publishing date 2020-10-01
    Publishing country Italy
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 2083309-X
    ISSN 1128-045X ; 1123-6337
    ISSN (online) 1128-045X
    ISSN 1123-6337
    DOI 10.1007/s10151-020-02347-x
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  6. Article ; Online: A dramatic and rare complication: bowel perforation following abdominal liposuction.

    Giordano, Angela / Alemanno, G / Bici, K / Prosperi, P / Viligiardi, R / Bisogni, D / Iacopini, V / Dibella, A / Valeri, A

    Il Giornale di chirurgia

    2020  Volume 40, Issue 5, Page(s) 429–432

    Abstract: Aim: The purpose of this study is to analyze a rare and under-reported complication of abdominal liposuction and the role of laparoscopy.: Clinical case: We report a case of bowel perforation after 7 days of abdominal liposuction and bilateral ... ...

    Abstract Aim: The purpose of this study is to analyze a rare and under-reported complication of abdominal liposuction and the role of laparoscopy.
    Clinical case: We report a case of bowel perforation after 7 days of abdominal liposuction and bilateral mastopexy. The patient presented clinical and radiological findings of bowel obstructive syndrome and bilateral peripheral pulmonary embolism. An emergency diagnostic laparoscopy was performed and confirmed the diagnosis of bowel perforation.
    Discussion: Bowel perforation is a known but under-reported comSOD Romaplication of abdominal liposuction, and it is characterized by a difficult diagnosis. The clinical presentation is characterized by a difficult diagnosis and severe complications. Bowel obstructive syndrome was constant, as our case and also peritonitis was never frank. This is an important point because it is one of the reasons for diagnostic delay. The development of laparoscopic surgery has changed the way to manage such conditions, where the diagnosis was doubt. In particular, when an acute abdomen occurs, laparoscopy may have three different roles: to confirm or not the diagnosis, to facilitate and guide a subsequent laparotomy or, finally, to entirely treat the disease.
    Conclusion: The bowel perforation is a dramatic and underestimated complication of abdominal liposuction. Diagnosis is complex. A clinical and radiological investigation should be quickly performed. In doubtful cases, an emergency laparoscopy can confirm the diagnosis and guide a possible subsequent laparotomy.
    MeSH term(s) Abdomen ; Humans ; Intestinal Perforation/diagnosis ; Intestinal Perforation/etiology ; Laparoscopy ; Lipectomy/adverse effects ; Postoperative Complications/etiology
    Language English
    Publishing date 2020-01-30
    Publishing country Italy
    Document type Case Reports ; Journal Article
    ZDB-ID 605974-0
    ISSN 1971-145X ; 0391-9005
    ISSN (online) 1971-145X
    ISSN 0391-9005
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  7. Article: Laparoscopic adrenalectomy for giant adrenal tumours: Technical considerations and surgical outcome.

    Giordano, Alessio / Alemanno, Giovanni / Bergamini, Carlo / Valeri, Andrea / Prosperi, Paolo

    Journal of minimal access surgery

    2020  Volume 17, Issue 1, Page(s) 76–80

    Abstract: Background: Giant adrenal tumours are tumours with size ≥6 cm. These are rare cancer associated with malignancy in 25% of cases.: Patients and methods: A retrospective review was conducted on the medical records of patients admitted to our high- ... ...

    Abstract Background: Giant adrenal tumours are tumours with size ≥6 cm. These are rare cancer associated with malignancy in 25% of cases.
    Patients and methods: A retrospective review was conducted on the medical records of patients admitted to our high-volume centre of Careggi University Hospital with a giant adrenal tumour and submitted to adrenalectomy between January 2008 and December 2018. The group of patients who underwent to laparoscopic adrenalectomy was compared with a group of patients that was submitted to open adrenalectomy.
    Results: In the past 10 years, we performed about 245 adrenalectomies for benign and malignant adrenal tumours. Fifty (20.4%) of these were giant tumours. The medium size was 9.9 cm (7-22 cm). The mean age was 57 years (21-81 years). Thirty-four (68%) of these cancers were laparoscopically removed and 16 (32%) with an open approach. The surgical outcomes in these patients were optimal if compared to the group of patients submitted to open approach in terms of good pain control, hospital stay, mean operative time and bloodless. No difference was observed about post-operative complications in the two groups. The follow-up after 30 months for malignant tumours did not show local recurrences.
    Conclusion: Our results pinpoint the advantages of performing a laparoscopic adrenalectomy for giant adrenal tumours. The tumour size is only a predictive parameter of possible malignancy, and the laparoscopic approach is a safe and feasible method in terms of surgical and oncological, only if performed by expert surgeons and in high-volume centres.
    Language English
    Publishing date 2020-02-25
    Publishing country India
    Document type Journal Article
    ZDB-ID 2186884-0
    ISSN 1998-3921 ; 0972-9941
    ISSN (online) 1998-3921
    ISSN 0972-9941
    DOI 10.4103/jmas.JMAS_266_19
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  8. Article ; Online: Laparoscopic splenectomy after failure of nonoperative management - a video vignette.

    Giordano, Alessio / Bruscino, Alessandro / Bergamini, Carlo / Alemanno, Giovanni / Valeri, Andrea / Prosperi, Paolo

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

    2021  Volume 23, Issue 4, Page(s) 1014–1015

    MeSH term(s) Abdominal Injuries/surgery ; Humans ; Laparoscopy ; Spleen ; Splenectomy
    Language English
    Publishing date 2021-02-08
    Publishing country England
    Document type Letter ; Video-Audio Media
    ZDB-ID 1440017-0
    ISSN 1463-1318 ; 1462-8910
    ISSN (online) 1463-1318
    ISSN 1462-8910
    DOI 10.1111/codi.15535
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  9. Article: Open abdomen management for massive intestinal infarction due to acute splanchnic venous thrombosis in a patient with protein S deficiency. A case report.

    Di Bella, Annamaria / Bruscino, Alessandro / Alemanno, Giovanni / Bergamini, Carlo / Prosperi, Paolo

    International journal of surgery case reports

    2020  Volume 72, Page(s) 122–126

    Abstract: Introduction: Acute mesenteric ischemia (AMI) refers to the sudden onset of intestinal hypoperfusion that can also result from splanchnic venous occlusion. The portomesenteric venous system (PMVS) is an unusual site of thrombosis in patients with ... ...

    Abstract Introduction: Acute mesenteric ischemia (AMI) refers to the sudden onset of intestinal hypoperfusion that can also result from splanchnic venous occlusion. The portomesenteric venous system (PMVS) is an unusual site of thrombosis in patients with protein S deficiency and its obstruction is a rare cause of AMI. Aim of this report is to illustrate a successful strategy in a case of massive small bowel infarction managed with an open abdomen (OA) approach.
    Case presentation: A 64 year-old woman presented to the emergency department with acute abdominal pain, rectal bleeding, diarrhea and vomiting. Contrast-enhanced computed tomography (CECT) showed small bowel ischemia and the complete occlusion of all the PMVS branches. Surgery was performed with an OA approach and anticoagulation was immediately begun. Further workup revealed isolated protein S deficiency and history of atrophic gastritis. Thromboprophylaxis with warfarin was started on discharge and no recurrence of thrombotic events was recorded during the one-year follow-up.
    Discussion: PMVS thrombosis related to protein S deficiency is a rare condition that can rapidly lead to an acute abdomen. CECT is the gold standard, because it detects splanchnic thrombosis and its possible complications, like bowel ischemia. In case of surgery, a planned second-look operation is the best strategy to assess bowel viability and possible ischemic progression.
    Conclusions: OA management plays a fundamental role in case of resection for bowel ischemia. Patients with thrombosis at an uncommon site should be further investigated for prothrombotic states.
    Language English
    Publishing date 2020-06-06
    Publishing country Netherlands
    Document type Case Reports
    ISSN 2210-2612
    ISSN 2210-2612
    DOI 10.1016/j.ijscr.2020.05.076
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  10. Article ; Online: Surgical perspectives and patways in an emergency department during the COVID-19 pandemic.

    Alemanno, Giovanni / Tomaiuolo, Matteo / Peris, Adriano / Batacchi, Stefano / Nozzoli, Carlo / Prosperi, Paolo

    American journal of surgery

    2020  Volume 220, Issue 1, Page(s) 50–52

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/diagnosis ; Emergency Service, Hospital/organization & administration ; Emergency Service, Hospital/standards ; Hospitals/standards ; Hospitals, University/organization & administration ; Hospitals, University/standards ; Humans ; Infection Control/organization & administration ; Infection Control/standards ; Italy ; Pandemics ; Pneumonia, Viral/diagnosis ; SARS-CoV-2 ; Surgical Procedures, Operative/standards
    Keywords covid19
    Language English
    Publishing date 2020-05-13
    Publishing country United States
    Document type Editorial
    ZDB-ID 2953-1
    ISSN 1879-1883 ; 0002-9610
    ISSN (online) 1879-1883
    ISSN 0002-9610
    DOI 10.1016/j.amjsurg.2020.05.010
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