LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 46

Search options

  1. Book ; Article ; Online: Russia

    Alexander Gusev

    Sustainable Energy in the G20: Prospects for a Global Energy Transition ; IASS Study

    A Gas Superpower Striving for Nuclear Expansion and Starting to Support Renewables

    2016  

    Abstract: Russia has the fourth highest electricity demand globally. In the mid- and long-term, fossil fuels (gas, oil and coal) and nuclear energy will remain the backbone of Russian domestic and international energy policies. Russia is spearheading international ...

    Abstract Russia has the fourth highest electricity demand globally. In the mid- and long-term, fossil fuels (gas, oil and coal) and nuclear energy will remain the backbone of Russian domestic and international energy policies. Russia is spearheading international support for nuclear power. Recent governmental decisions clearly show growing support for renewables. Despite overall budget cuts, renewable energy has for the first time received direct financial support from the federal budget. While energy efficiency policies have experienced substantial setbacks in recent years, gasification of public transport could further contribute to decarbonisation.
    Language English
    Publisher Institute for Advanced Sustainability Studies (IASS)
    Publishing country de
    Document type Book ; Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Book ; Online: The EU-Russia Energy Game – Who’s in the Lead?

    Alexander Gusev

    The International Relations and Security Network

    2014  

    Language English
    Publishing country de
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Book ; Online: Shale gas

    Alexander Gusev

    energy post

    what it could really mean for Europe

    2014  

    Language English
    Publishing country de
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Article ; Online: Users’ Reaction Time for Improvement of Security and Access Control in Web Services

    Shamil Magomedov / Alexander Gusev / Dmitry Ilin / Evgeny Nikulchev

    Applied Sciences, Vol 11, Iss 2561, p

    2021  Volume 2561

    Abstract: This paper concerns the case of the development of a technology for increasing the efficiency of access control based on the user behavior monitoring built into a software system’s user interface. It is proposed to use the time of user reactions as ... ...

    Abstract This paper concerns the case of the development of a technology for increasing the efficiency of access control based on the user behavior monitoring built into a software system’s user interface. It is proposed to use the time of user reactions as individual indicators of psychological and psychophysical state. This paper presents the results and interpretation of user reactions collected during a mass web survey of students of the Russian Federation. The total number of users was equal to 22,357. To reveal the patterns in user reactions, both quantitative and qualitative approaches were applied. The analysis of the data demonstrated that the user could be characterized by their psychomotor reactions, collected during the answering of a set of questions. Those reactions reflected the personal skills of the interface interaction, the speed of reading, and the speed of answering. Thus, those observations can be used as a supplement to personal verification in information systems. The collection of the reaction times did not load the data volumes significantly nor transmit confidential information.
    Keywords big data ; analysis of user reactions ; patterns in user reactions ; personal verification in information systems ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
    Subject code 005
    Language English
    Publishing date 2021-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Article ; Online: Cyan Fluorescent Carbon Quantum Dots with Amino Derivatives for the Visual Detection of Copper (II) Cations in Sea Water

    Anastasia Yakusheva / Mohamed Aly-Eldeen / Alexander Gusev / Olga Zakharova / Denis Kuznetsov

    Nanomaterials, Vol 13, Iss 1004, p

    2023  Volume 1004

    Abstract: Amino- and carboxyl-functionalized carbon quantum dots (Amino-CQDs) were synthesized through fast and simple microwave treatment of a citric acid, ethylenediamine and ethylenediaminetetraacetic acid (EDTA) mix. The reproducible and stable optical ... ...

    Abstract Amino- and carboxyl-functionalized carbon quantum dots (Amino-CQDs) were synthesized through fast and simple microwave treatment of a citric acid, ethylenediamine and ethylenediaminetetraacetic acid (EDTA) mix. The reproducible and stable optical properties from newly synthesized CQD dispersion with a maximum absorbance spectra at 330 nm and the symmetric emission maximum at 470 nm made the Amino-CQDs a promising fluorescence material for analytical applications. The highly aminated and chelate moieties on the CQDs was appropriate for a copper (Cu 2+ ) cation sensor in the linear range from 1 × 10 −4 mg/mL to 10 mg/mL with a limit of detection at 0.00036 mg/mL by static fluorescence quenching effects. Furthermore, Amino-CQDs demonstrated stable fluorescence parameters for assays in diluted alkali metal solution (Na + and K + ) and sea water. Finally, a visual sensor, based on Amino-CQDs, was successfully created for the 0.01–100 mg/mL range to produce a colorimetric effect that can be registered by computer vision software (Open CV Python).
    Keywords carbon quantum dots ; fluorescence quenching ; amino derivatives ; water safety ; copper sensor ; seawater ; Chemistry ; QD1-999
    Subject code 333
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Article ; Online: INVESTIGATION OF THE KOLMOGOROV-WIENER FILTER FOR CONTINUOUS FRACTAL PROCESSES ON THE BASIS OF THE CHEBYSHEV POLYNOMIALS OF THE FIRST KIND

    Vyacheslav Gorev / Alexander Gusev / Valerii Korniienko

    Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska, Vol 10, Iss

    2020  Volume 1

    Abstract: This paper is devoted to the investigation of the Kolmogorov-Wiener filter weight function for continuous fractal processes with a power-law structure function. The corresponding weight function is sought as an approximate solution to the Wiener-Hopf ... ...

    Abstract This paper is devoted to the investigation of the Kolmogorov-Wiener filter weight function for continuous fractal processes with a power-law structure function. The corresponding weight function is sought as an approximate solution to the Wiener-Hopf integral equation. The truncated polynomial expansion method is used. The solution is obtained on the basis of the Chebyshev polynomials of the first kind. The results are compared with the results of the authors’ previous investigations devoted to the same problem where other polynomial sets were used. It is shown that different polynomial sets present almost the same behaviour of the solution convergence.
    Keywords continuous fractal processes ; Kolmogorov–Wiener filter weight function ; Chebyshev polynomials of the first kind ; Environmental engineering ; TA170-171 ; Environmental sciences ; GE1-350
    Language English
    Publishing date 2020-03-01T00:00:00Z
    Publisher Lublin University of Technology
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  7. Article ; Online: Evaluation of User Reactions and Verification of the Authenticity of the User’s Identity during a Long Web Survey

    Evgeny Nikulchev / Alexander Gusev / Dmitry Ilin / Nurziya Gazanova / Sergey Malykh

    Applied Sciences, Vol 11, Iss 11034, p

    2021  Volume 11034

    Abstract: Web surveys are very popular in the Internet space. Web surveys are widely incorporated for gathering customer opinion about Internet services, for sociological and psychological research, and as part of the knowledge testing systems in electronic ... ...

    Abstract Web surveys are very popular in the Internet space. Web surveys are widely incorporated for gathering customer opinion about Internet services, for sociological and psychological research, and as part of the knowledge testing systems in electronic learning. When conducting web surveys, one of the issues to consider is the respondents’ authenticity throughout the entire survey process. We took 20,000 responses to an online questionnaire as experimental data. The survey took about 45 min on average. We did not take into account the given answers; we only considered the response time to the first question on each page of the survey interface, that is, only the users’ reaction time was taken into account. Data analysis showed that respondents get used to the interface elements and want to finish a long survey as soon as possible, which leads to quicker reactions. Based on the data, we built two neural network models that identify the records in which the respondent’s authenticity was violated or the respondent acted as a random clicker. The amount of data allows us to conclude that the identified dependencies are widely applicable.
    Keywords reaction time to interface elements ; web surveys ; web polls ; random clickers ; long questionnaires ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
    Subject code 310
    Language English
    Publishing date 2021-11-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  8. Article ; Online: Somatic mutational profiles and germline polygenic risk scores in human cancer

    Yuxi Liu / Alexander Gusev / Yujing J. Heng / Ludmil B. Alexandrov / Peter Kraft

    Genome Medicine, Vol 14, Iss 1, Pp 1-

    2022  Volume 16

    Abstract: Abstract Background The mutational profile of cancer reflects the activity of the mutagenic processes which have been operative throughout the lineage of the cancer cell. These processes leave characteristic profiles of somatic mutations called ... ...

    Abstract Abstract Background The mutational profile of cancer reflects the activity of the mutagenic processes which have been operative throughout the lineage of the cancer cell. These processes leave characteristic profiles of somatic mutations called mutational signatures. Mutational signatures, including single-base substitution (SBS) signatures, may reflect the effects of exogenous or endogenous exposures. Methods We used polygenic risk scores (PRS) to summarize common germline variation associated with cancer risk and other cancer-related traits and examined the association between somatic mutational profiles and germline PRS in 12 cancer types from The Cancer Genome Atlas. Somatic mutational profiles were constructed from whole-exome sequencing data of primary tumors. PRS were calculated for the 12 selected cancer types and 9 non-cancer traits, including cancer risk determinants, hormonal factors, and immune-mediated inflammatory diseases, using germline genetic data and published summary statistics from genome-wide association studies. Results We found 17 statistically significant associations between somatic mutational profiles and germline PRS after Bonferroni correction (p < 3.15 × 10−5), including positive associations between germline inflammatory bowel disease PRS and number of somatic mutations attributed to signature SBS1 in prostate cancer and APOBEC-related signatures in breast cancer. Positive associations were also found between age at menarche PRS and mutation counts of SBS1 in overall and estrogen receptor-positive breast cancer. Consistent with prior studies that found an inverse association between the pubertal development PRS and risk of prostate cancer, likely reflecting hormone-related mechanisms, we found an inverse association between age at menarche PRS and mutation counts of SBS1 in prostate cancer. Inverse associations were also found between several cancer PRS and tumor mutation counts. Conclusions Our analysis suggests that there are robust associations between tumor somatic mutational profiles and germline PRS. These may reflect the mechanisms through hormone regulation and immune responses that contribute to cancer etiology and drive cancer progression.
    Keywords Somatic mutation ; Mutational signature ; Single-base substitution signature ; Polygenic risk score ; Cancer ; Medicine ; R ; Genetics ; QH426-470
    Subject code 610
    Language English
    Publishing date 2022-02-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Article ; Online: Optimized homomorphic encryption solution for secure genome-wide association studies

    Marcelo Blatt / Alexander Gusev / Yuriy Polyakov / Kurt Rohloff / Vinod Vaikuntanathan

    BMC Medical Genomics, Vol 13, Iss S7, Pp 1-

    2020  Volume 13

    Abstract: Abstract Background Genome-Wide Association Studies (GWAS) refer to observational studies of a genome-wide set of genetic variants across many individuals to see if any genetic variants are associated with a certain trait. A typical GWAS analysis of a ... ...

    Abstract Abstract Background Genome-Wide Association Studies (GWAS) refer to observational studies of a genome-wide set of genetic variants across many individuals to see if any genetic variants are associated with a certain trait. A typical GWAS analysis of a disease phenotype involves iterative logistic regression of a case/control phenotype on a single-neuclotide polymorphism (SNP) with quantitative covariates. GWAS have been a highly successful approach for identifying genetic-variant associations with many poorly-understood diseases. However, a major limitation of GWAS is the dependence on individual-level genotype/phenotype data and the corresponding privacy concerns. Methods We present a solution for secure GWAS using homomorphic encryption (HE) that keeps all individual data encrypted throughout the association study. Our solution is based on an optimized semi-parallel GWAS compute model, a new Residue-Number-System (RNS) variant of the Cheon-Kim-Kim-Song (CKKS) HE scheme, novel techniques to switch between data encodings, and more than a dozen crypto-engineering optimizations. Results Our prototype can perform the full GWAS computation for 1,000 individuals, 131,071 SNPs, and 3 covariates in about 10 minutes on a modern server computing node (with 28 cores). Our solution for a smaller dataset was awarded co-first place in iDASH’18 Track 2: “Secure Parallel Genome Wide Association Studies using HE”. Conclusions Many of the HE optimizations presented in our paper are general-purpose, and can be used in solving challenging problems with large datasets in other application domains.
    Keywords Cryptography ; Homomorphic encryption ; Genome-wide association studies ; Internal medicine ; RC31-1245 ; Genetics ; QH426-470
    Subject code 006
    Language English
    Publishing date 2020-07-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  10. Book ; Article ; Online: Die ungewissen Klimakosten von Erdgas

    Lorenzo Cremonese / Alexander Gusev

    IASS Working Paper

    Bewertung der Unstimmigkeiten in den Daten zu Methanlecks in Europa, Russland und den USA und deren Auswirkungen auf die Nachhaltigkeit

    2016  

    Abstract: Die vorliegende Studie beinhaltet einen Vergleich einiger diesbezüglich relevanter Länder: der USA, Deutschland, der Niederlande und Russland. Neben einer kritischen Überprüfung des jeweiligen nationalen Status quo (z. B. im Hinblick auf Datenbeschaffung, ...

    Abstract Die vorliegende Studie beinhaltet einen Vergleich einiger diesbezüglich relevanter Länder: der USA, Deutschland, der Niederlande und Russland. Neben einer kritischen Überprüfung des jeweiligen nationalen Status quo (z. B. im Hinblick auf Datenbeschaffung, Überwachung etc.) konzentriert sie sich auf die ausgeprägten Unstimmigkeiten bezüglich der in jedem einzelnen Gassegment gemeldeten Gasverluste. Von besonderer Bedeutung sind dabei die USA, wo die Schätzungen der Upstream-Gasleckraten (Exploration, Förderung, Produktion) wesentlich höher ausfallen als die entsprechenden Raten in Europa. An Überprüfungen dieser Art mangelt es nach wie vor weltweit, obwohl das Bewusstsein für dieses Problem zunimmt, was wiederum verschiedene Initiativen internationaler Institutionen [Wirtschaftskommission für Europa der Vereinten Nationen (United Nations Economic Commission for Europe, UNECE)], NGOs [Bündnis für Klima und saubere Luft (Oil & Gas Methane Partnership, Climate and Clean Air Coalition, CCAC)] und Gasbetreiber (Marcogaz) belegen. Um die ehrgeizigen internationalen Ziele zu erreichen, die im Pariser Klimaabkommen festgeschrieben wurden, müssen die politischen Entscheidungsträger in Zusammenarbeit mit der Erdgasindustrie zeitnah angemessene Maßnahmen ergreifen, die darauf abzielen, die Methanemissionen, deren Auswirkungen auf die globale Temperatur ähnlich besorgniserregend sind wie die von Kohlendioxid, empirisch zu überprüfen und zu reduzieren.
    Subject code 320
    Language German
    Publisher Institute for Advanced Sustainability Studies (IASS)
    Publishing country de
    Document type Book ; Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top