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  1. AU="Alexandra Griffith"
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  1. Article ; Online: Cells and material-based strategies for regenerative endodontics

    Zain Siddiqui / Amanda M. Acevedo-Jake / Alexandra Griffith / Nurten Kadincesme / Kinga Dabek / Dana Hindi / Ka Kyung Kim / Yoshifumi Kobayashi / Emi Shimizu / Vivek Kumar

    Bioactive Materials, Vol 14, Iss , Pp 234-

    2022  Volume 249

    Abstract: The carious process leads to inflammation of pulp tissue. Current care options include root canal treatment or apexification. These procedures, however, result in the loss of tooth vitality, sensitivity, and healing. Pulp capping and dental pulp ... ...

    Abstract The carious process leads to inflammation of pulp tissue. Current care options include root canal treatment or apexification. These procedures, however, result in the loss of tooth vitality, sensitivity, and healing. Pulp capping and dental pulp regeneration are continually evolving techniques to regenerate pulp tissue, avoiding necrosis and loss of vitality. Many studies have successfully employed stem/progenitor cell populations, revascularization approaches, scaffolds or material-based strategies for pulp regeneration. Here we outline advantages and disadvantages of different methods and techniques which are currently being used in the field of regenerative endodontics. We also summarize recent findings on efficacious peptide-based materials which target the dental niche.
    Keywords Regenerative endodontics ; Pulp regeneration ; Tissue engineering ; Stem cells ; Scaffolds ; Materials of engineering and construction. Mechanics of materials ; TA401-492 ; Biology (General) ; QH301-705.5
    Subject code 670
    Language English
    Publishing date 2022-08-01T00:00:00Z
    Publisher KeAi Communications Co., Ltd.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: WASP-mediated regulation of anti-inflammatory macrophages is IL-10 dependent and is critical for intestinal homeostasis

    Amlan Biswas / Dror S. Shouval / Alexandra Griffith / Jeremy A. Goettel / Michael Field / Yu Hui Kang / Liza Konnikova / Erin Janssen / Naresh Singh Redhu / Adrian J. Thrasher / Talal Chatila / Vijay K. Kuchroo / Raif S Geha / Luigi D. Notarangelo / Sung-Yun Pai / Bruce H. Horwitz / Scott B. Snapper

    Nature Communications, Vol 9, Iss 1, Pp 1-

    2018  Volume 15

    Abstract: Deficiency in Wiskott-Aldrich syndrome protein (WASP) has been associated with autoimmune colitis, but the underlying mechanism is still unclear. Here the authors show that WASP deficiency is associated with defective WASP/DOCK8 complex formation, ... ...

    Abstract Deficiency in Wiskott-Aldrich syndrome protein (WASP) has been associated with autoimmune colitis, but the underlying mechanism is still unclear. Here the authors show that WASP deficiency is associated with defective WASP/DOCK8 complex formation, altered IL-10 signalling, and impaired anti-inflammatory macrophage functions.
    Keywords Science ; Q
    Language English
    Publishing date 2018-05-01T00:00:00Z
    Publisher Nature Publishing Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: WASP-mediated regulation of anti-inflammatory macrophages is IL-10 dependent and is critical for intestinal homeostasis

    Amlan Biswas / Dror S. Shouval / Alexandra Griffith / Jeremy A. Goettel / Michael Field / Yu Hui Kang / Liza Konnikova / Erin Janssen / Naresh Singh Redhu / Adrian J. Thrasher / Talal Chatila / Vijay K. Kuchroo / Raif S Geha / Luigi D. Notarangelo / Sung-Yun Pai / Bruce H. Horwitz / Scott B. Snapper

    Nature Communications, Vol 9, Iss 1, Pp 1-

    2018  Volume 15

    Abstract: Deficiency in Wiskott-Aldrich syndrome protein (WASP) has been associated with autoimmune colitis, but the underlying mechanism is still unclear. Here the authors show that WASP deficiency is associated with defective WASP/DOCK8 complex formation, ... ...

    Abstract Deficiency in Wiskott-Aldrich syndrome protein (WASP) has been associated with autoimmune colitis, but the underlying mechanism is still unclear. Here the authors show that WASP deficiency is associated with defective WASP/DOCK8 complex formation, altered IL-10 signalling, and impaired anti-inflammatory macrophage functions.
    Keywords Science ; Q
    Language English
    Publishing date 2018-05-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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