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  1. Article ; Online: Análise da influência do momento do ingresso em creches no desenvolvimento infantil

    Christyann Lima Campos Batista / Alexandra Valéria Maria Brentani

    Cadernos de Saúde Pública, Vol 39, Iss

    2023  Volume 4

    Abstract: Este estudo objetivou analisar a relação entre a idade de ingresso nos programas de educação na primeira infância (EPI) e o desenvolvimento infantil. Trata-se de um estudo transversal com dados oriundos da Coorte de Nascimentos da Região Oeste de São ... ...

    Abstract Este estudo objetivou analisar a relação entre a idade de ingresso nos programas de educação na primeira infância (EPI) e o desenvolvimento infantil. Trata-se de um estudo transversal com dados oriundos da Coorte de Nascimentos da Região Oeste de São Paulo, Brasil. Realizou-se o acompanhamento de crianças nascidas no Hospital Universitário da Universidade de São Paulo durante 36 meses, entre os anos de 2012 e 2014, e de seus cuidadores respondentes durante a onda de seguimentos dos 36 meses de idade (realizada entre os anos de 2015 e 2017). O desenvolvimento infantil foi mensurado pelo instrumento Engle Scale do Projeto Regional de Indicadores de Desenvolvimento Infantil (PRIDI). Os programas de EPI foram avaliados em relação a sua qualidade. Foram utilizadas como variáveis expositivas as características sociais das crianças e dos seus cuidadores, bem como as características do contexto econômico e familiar. A amostra foi composta por 472 crianças e cuidadores. Observou-se que o ingresso na creche entre 13 e 29 meses foi o mais frequente. Quando considerados isoladamente, observou-se que uma maior idade de ingresso esteve associada com maior escore de desenvolvimento [β = 0,21, IC95%: 0,02; 0,40, p = 0,027]. Após a inclusão das variáveis de ajuste nos modelos de regressão, observou-se que estar inscrito em instituição do tipo privada, tempo total de aleitamento materno, horas trabalhadas fora de casa pelo cuidador principal e o controle inibitório foram determinantes para explicar o desenvolvimento infantil aos 36 meses na amostra. A idade de ingresso mais tardia nos programas de EPI pode ter efeito positivo sobre o desenvolvimento infantil aos 36 meses de idade, porém esses achados precisam ser ponderados.
    Keywords Desenvolvimento Infantil ; Creches ; Cuidadores ; Criança ; Medicine ; R ; Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2023-04-01T00:00:00Z
    Publisher Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Association between community noise and children’s cognitive and behavioral development

    Michelle Raess / Alexandra Valeria Maria Brentani / Benjamin Flückiger / Bartolomeu Ledebur de Antas de Campos / Günther Fink / Martin Röösli

    Environment International, Vol 158, Iss , Pp 106961- (2022)

    A prospective cohort study

    1479  

    Abstract: Background: Noise exposure has been associated with adverse cognitive and behavioral outcomes in children, but evidence on longitudinal associations between community noise and child development in low- and middle-income countries is rare. We ... ...

    Abstract Background: Noise exposure has been associated with adverse cognitive and behavioral outcomes in children, but evidence on longitudinal associations between community noise and child development in low- and middle-income countries is rare. We investigated associations between community noise and behavioral and cognitive development in preschool children in São Paulo. Methods: We linked child development data from the São Paulo Western Region Birth Cohort with average (Lden) and night-time (Lnight) community noise exposure at children's home, estimated by means of a land use regression model using various predictors (roads, schools, greenness, residential and informal settlements). Outcomes were the Strengths and Difficulties Questionnaire (SDQ) and Regional Project on Child Development Indicators (PRIDI) at 3 years of age and the Child Behavior Checklist (CBCL) and International Development and Early Learning Assessment (IDELA) at 6 years of age. We investigated the relationship between noise exposure and development using cross-sectional and longitudinal regression models. Results: Data from 3385 children at 3 years of age and 1546 children at 6 years of age were analysed. Mean Lden and Lnight levels were 70.3 dB and 61.2 dB, respectively. In cross-sectional analyses a 10 dB increase of Lden above 70 dB was associated with a 32% increase in the odds of borderline or abnormal SDQ total difficulties score (OR = 1.32, 95% CI: 1.04; 1.68) and 0.72 standard deviation (SD) increase in the CBCL total problems z-score (95% CI: 0.55; 0.88). No cross-sectional association was found for cognitive development. In longitudinal analyses, each 10 dB increase was associated with a 0.52 SD increase in behavioral problems (95% CI: 0.28; 0.77) and a 0.27 SD decrease in cognition (95%-CI: 0.55; 0.00). Results for Lnight above 60 dB were similar. Discussion: Our findings suggest that community noise exposure above Lden of 70 dB and Lnight of 60 dB may impair behavioral and cognitive development of preschool children.
    Keywords Noise exposure ; Community noise ; São Paulo ; Cognitive development ; behavioral problems ; Environmental sciences ; GE1-350
    Subject code 360
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: The Intergenerational Effects on Birth Weight and Its Relations to Maternal Conditions, São Paulo, Brazil

    Leide Irislayne Macena da Costa e Silva / Filumena Maria da Silva Gomes / Maria Helena Valente / Ana Maria de Ulhôa Escobar / Alexandra Valéria Maria Brentani / Sandra J. F. E. Grisi

    BioMed Research International, Vol

    2015  Volume 2015

    Abstract: Background and Objectives. Parents’ birth weight acts as a predictor for the descendant birth weight, with the correlation more strongly transmitted through maternal line. The present research aims to study the correlation between the child’s low or ... ...

    Abstract Background and Objectives. Parents’ birth weight acts as a predictor for the descendant birth weight, with the correlation more strongly transmitted through maternal line. The present research aims to study the correlation between the child’s low or increased birth weight, the mother’s birth weight, and maternal conditions. Methods. 773 mother-infant binomials were identified with information on both the baby’s and the mother’s birth weight recorded. Group studies were constituted, dividing the sample according to birth weight (<2,500 grams (g) and ≥3,500 grams (g)). The length at birth was also studied in children ≤47.5 cm (lower quartile). Chi2 test or Fisher’s exact test, Spearman’s Rho, and odds ratio were performed in order to investigate the relation between the children’s weight and length at birth and the mothers’ and children’s variables. Results. The girls were heavier at birth than their mothers, with an average increase at birth weight between the generations of 79 g. The child’s birth weight <2,500 g did not show any correlation with maternal birth weight <2,500 g (Fisher 0.264; Spearman’s Rho 0.048; OR 2.1 and OR lower 0.7) or with maternal stature below the lower quartile (<157 cm) (Chi2 sig 0.323; with Spearman’s Rho 0.036; OR 1.5 and OR lower 0.7). The child’s low birth weight (<2,500 g) was lightly correlated with drug use by the mother during pregnancy (Fisher 0.083; Spearman’s Rho 0.080; OR 4.9 and OR lower 1.0). The child’s birth weight <2,500 g showed increased correlation with gestational age lower than 38 weeks and 3 days (Chi2 sig 0.002; Spearman’s Rho 0.113; OR 3.2 and OR lower 1.5). The child’s weight at birth ≥3,500 g showed strong correlation with maternal weight at birth ≥3,500 g (Chi2 sig 0; Spearman’s Rho +0.142; OR 0.5 and OR upper 0.7). It was also revealed that the higher the maternal prepregnancy BMI, the stronger the correlation with child’s birth weight ≥3,500 g ((maternal prepregnancy BMI>25.0 with Chi2 sig 0.013; Spearman’s Rho 0.09; OR 1.54 and OR ...
    Keywords Medicine ; R
    Subject code 630
    Language English
    Publishing date 2015-01-01T00:00:00Z
    Publisher Hindawi Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Relation between Birth Weight, Growth, and Subclinical Atherosclerosis in Adulthood

    Maria Helena Valente / Filumena Maria da Silva Gomes / Isabela Judith Martins Benseñor / Alexandra Valéria Maria Brentani / Ana Maria de Ulhôa Escobar / Sandra J. F. E. Grisi

    BioMed Research International, Vol

    2015  Volume 2015

    Abstract: Background and Objectives. Adverse conditions in the prenatal environment and in the first years of life are independently associated with increased risk for cardiovascular disease. This paper aims to study the relation between birthweight, growth in the ...

    Abstract Background and Objectives. Adverse conditions in the prenatal environment and in the first years of life are independently associated with increased risk for cardiovascular disease. This paper aims to study the relation between birthweight, growth in the first year of life, and subclinical atherosclerosis in adults. Methods. 88 adults aged between 20 and 31 were submitted to sociodemographic qualities, anthropometric data, blood pressure measurements, metabolic profile, and evaluation of subclinical atherosclerosis. Results. Birthweight <2,500 grams (g) was negatively correlated with (a) increased waist-to-hip ratio (WHR), according to regression coefficient (RC) equal to −0.323, 95% CI [−0.571, −0.075] P<0.05; (b) diastolic blood pressure (RC = −4.744, 95% CI [−9.017, −0.470] P<0.05); (c) low HDL-cholesterol (RC = −0.272, 95% CI [−0.516, −0.029] P<0.05); (d) frequency of intima-media thickness (IMT) of left carotid >75th percentile (RC = −0.242, 95% CI [−0.476, −0.008] P<0.05). Birthweight >3,500 g was associated with (a) BMI >25.0 kg/m2, (RC = 0.317, 95% CI [0.782, 0.557] P<0.05); (b) increased waist circumference (RC = 0.284, 95% CI [0.054, 0.513] P<0.05); (c) elevated WHR (RC = 0.280, 95% CI [0.054, 0.505] P<0.05); (d) minimum subcutaneous adipose tissue (SAT) (RC = 4.354, 95% CI [0.821, 7.888] P<0.05); (e) maximum SAT (RC = 7.095, 95% CI [0.608, 13.583] P<0.05); (f) right lobe of the liver side (RC = 6.896, 95% CI [1.946, 11.847] P<0.001); (g) frequency’s right lobe of the liver >75th percentile (RC = 0.361, 95% CI [0.169, 0.552] P<0.001). Weight gain in the first year of life was inversely correlated with (a) mean IMT of left carotid (RC = −0.046, 95% CI [−0.086, −0.006] P<0.05; (b) frequency IMT of left carotid >75th percentile (RC = −0.253, 95% CI [−0.487, −0.018] P<0.05); (c) mean IMT (RC = −0.038, 95% CI [0.073, −0.002] P<0.05); (d) the frequency of the mean IMT >75th percentile (RC = −0.241, 95% CI [−0.442, −0.041] P<0.05). Conclusions. ...
    Keywords Medicine ; R
    Subject code 616
    Language English
    Publishing date 2015-01-01T00:00:00Z
    Publisher Hindawi Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Differences in children and adolescents with SARS-CoV-2 infection

    Heloisa Helena de Sousa Marques / Maria Fernanda Badue Pereira / Angélica Carreira dos Santos / Thais Toledo Fink / Camila Sanson Yoshino de Paula / Nadia Litvinov / Claudio Schvartsman / Artur Figueiredo Delgado / Maria Augusta Bento Cicaroni Gibelli / Werther Brunow de Carvalho / Vicente Odone Filho / Uenis Tannuri / Magda Carneiro-Sampaio / Sandra Grisi / Alberto José da Silva Duarte / Leila Antonangelo / Rossana Pucineli Vieira Francisco / Thelma Suely Okay / Linamara Rizzo Batisttella /
    Carlos Roberto Ribeiro de Carvalho / Alexandra Valéria Maria Brentani / Clovis Artur Silva / Adriana Pasmanik Eisencraft / Alfio Rossi Junior / Alice Lima Fante / Aline Pivetta Cora / Amelia Gorete A. de Costa Reis / Ana Paula Scoleze Ferrer / Anarella Penha Meirelles de Andrade / Andreia Watanabe / Angelina Maria Freire Gonçalves / Aurora Rosaria Pagliara Waetge / Camila Altenfelder Silva / Carina Ceneviva / Carolina dos Santos Lazari / Deipara Monteiro Abellan / Emilly Henrique dos Santos / Ester Cerdeira Sabino / Fabíola Roberta Marim Bianchini / Flávio Ferraz de Paes Alcantara / Gabriel Frizzo Ramos / Gabriela Nunes Leal / Isadora Souza Rodriguez / João Renato Rebello Pinho / Jorge David Avaizoglou Carneiro / Jose Albino Paz / Juliana Carvalho Ferreira / Juliana Ferreira Ferranti / Juliana de Oliveira Achili Ferreira / Juliana Valéria de Souza Framil

    Clinics, Vol

    a cohort study in a Brazilian tertiary referral hospital

    2021  Volume 76

    Abstract: OBJECTIVES: To compare demographic/clinical/laboratory/treatments and outcomes among children and adolescents with laboratory-confirmed coronavirus disease 2019 (COVID-19). METHODS: This was a cross-sectional study that included patients diagnosed with ... ...

    Abstract OBJECTIVES: To compare demographic/clinical/laboratory/treatments and outcomes among children and adolescents with laboratory-confirmed coronavirus disease 2019 (COVID-19). METHODS: This was a cross-sectional study that included patients diagnosed with pediatric COVID-19 (aged <18 years) between April 11, 2020 and April 22, 2021. During this period, 102/5,951 (1.7%) of all admissions occurred in neonates, children, and adolescents. Furthermore, 3,962 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection samples were processed in patients aged <18 years, and laboratory-confirmed COVID-19 occurred in 155 (4%) inpatients and outpatients. Six/155 pediatric patients were excluded from the study. Therefore, the final group included 149 children and adolescents (n=97 inpatients and 52 outpatients) with positive SARS-CoV-2 results. RESULTS: The frequencies of sore throat, anosmia, dysgeusia, headache, myalgia, nausea, lymphopenia, pre-existing chronic conditions, immunosuppressive conditions, and autoimmune diseases were significantly reduced in children and adolescents (p<0.05). Likewise, the frequencies of enoxaparin use (p=0.037), current immunosuppressant use (p=0.008), vasoactive agents (p=0.045), arterial hypotension (p<0.001), and shock (p=0.024) were significantly lower in children than in adolescents. Logistic regression analysis showed that adolescents with laboratory-confirmed COVID-19 had increased odds ratios (ORs) for sore throat (OR 13.054; 95% confidence interval [CI] 2.750-61.977; p=0.001), nausea (OR 8.875; 95% CI 1.660-47.446; p=0.011), and lymphopenia (OR 3.575; 95% CI 1.355-9.430; p=0.010), but also had less hospitalizations (OR 0.355; 95% CI 0.138-0.916; p=0.032). The additional logistic regression analysis on patients with preexisting chronic conditions (n=108) showed that death as an outcome was significantly associated with pediatric severe acute respiratory syndrome (SARS) (OR 22.300; 95% CI 2.341-212.421; p=0.007) and multisystem inflammatory syndrome in children ...
    Keywords COVID-19 ; Children ; Adolescent ; Outcome ; Chronic Disease ; Multisystem Inflammatory Syndrome ; Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2021-11-01T00:00:00Z
    Publisher Elsevier España
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Association between maternal lifestyle and preschool nutrition

    Érica Bezerra Nobre / Alexandra Valéria Maria Brentani / Alexandre Archanjo Ferraro

    Revista da Associação Médica Brasileira, Vol 62, Iss 6, Pp 494-505

    Abstract: Summary Introduction: Many of the health behaviors involved in the emergence of chronic non-communicable diseases (CNCD) are originated in childhood under parental influence. Mothers are the ones most involved in the education and health care of children. ...

    Abstract Summary Introduction: Many of the health behaviors involved in the emergence of chronic non-communicable diseases (CNCD) are originated in childhood under parental influence. Mothers are the ones most involved in the education and health care of children. Lifestyle (LS) is a social determinant of health. Very few studies tried to understand the influence of maternal LS on child nutrition. Objective: To verify the association between maternal behavioral and non-behavioral LS and nutritional aspects in preschool children. Method: From January 2010 to December 2010, we performed a cross-sectional study with 255 mothers of preschool children who were residents of five different sub-districts in southwestern São Paulo. A proportional stratified random sample was selected using two layers (“schools” and “children”). From the mother, sociodemographic and LS information were collected. From the child, data on anthropometry, sedentary behavior and food intake were collected. The association was calculated using chi-square test and logistic regression. Results: Children who ate minimally processed food were born from mothers with more socially aware non-behavioral LS, while children that ate more processed food were born from mothers with more consumerist non-behavioral LS. No association was found between nutritional characteristics of preschoolers and types of maternal behavioral LS. Children presenting “sedentary behavior” and the habit of eating “ultra-processed foods” had 113% and 84% higher chances, respectively, of being born to mothers that belonged to the “consumerist” cluster. Conclusion: Mothers living a consumerist lifestyle can promote negative influences on child nutrition.
    Keywords mother-child relations ; lifestyle ; preschool child ; nutritional status ; motor activity ; child nutrition ; Medicine (General) ; R5-920
    Subject code 360
    Language English
    Publisher Associação Médica Brasileira
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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