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  1. Article ; Online: Should novice injectors treat every facial region in their first year of practice?

    Cotofana, Sebastian / Gold, Michael H / Biesman, Brian S / Alfertshofer, Michael

    Journal of cosmetic dermatology

    2024  Volume 23, Issue 6, Page(s) 2288–2289

    MeSH term(s) Humans ; Cosmetic Techniques ; Face ; Dermal Fillers/administration & dosage ; Clinical Competence ; Injections, Subcutaneous/instrumentation
    Language English
    Publishing date 2024-03-28
    Publishing country England
    Document type Letter
    ZDB-ID 2280551-5
    ISSN 1473-2165 ; 1473-2130
    ISSN (online) 1473-2165
    ISSN 1473-2130
    DOI 10.1111/jocd.16305
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6539: Show issues Location:
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  2. Article ; Online: Horizontal necklines correction with absorbable braided polydioxanone threads: Case series.

    Yi, Kyu-Ho / Kim, Soo-Bin / Chua, Deborah / Stefanelli, Matthieu Beustes / Alfertshofer, Michael / Vachiramon, Vasanop

    Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)

    2024  Volume 30, Issue 3, Page(s) e13617

    Abstract: Introduction: The prevalence of horizontal neck lines as a cosmetic concern is widely acknowledged, yet the available treatment options are limited, and no studies have investigated the use of polydioxanone-barbed threads. These threads, characterized ... ...

    Abstract Introduction: The prevalence of horizontal neck lines as a cosmetic concern is widely acknowledged, yet the available treatment options are limited, and no studies have investigated the use of polydioxanone-barbed threads. These threads, characterized by a finely braided structure, function as a scaffold to attract regenerative factors and facilitate the migration and proliferation of cells. This study aims to evaluate the outcomes of concurrent application of braided polydioxanone-barbed threads for addressing horizontal neck wrinkles.
    Methodology: A retrospective case series involving four female participants (aged 41, 43, 45, and 46) treated with polydioxanone-barbed threads for horizontal neck wrinkles between January 2023 and July 2023 was conducted. Adult patients were assessed at an 8-week follow-up, revealing a significant reduction in wrinkle intensity based on the Horizontal Neck Wrinkle Severity Scale.
    Results: The analysis of horizontal neck lines demonstrated a notable decrease in wrinkle intensity according to the Horizontal Neck Wrinkle Severity Scale at the 8-week mark, and this improvement maintained statistical significance. Both patient Global Aesthetic Improvement Scale (GAIS) scores (90%-100%) and physician GAIS scores (100%) were rated as excellent.
    Conclusion: The subdermal application of polydioxanone-barbed threads for horizontal neck lines proves to be a secure and efficacious approach for treating horizontal neck wrinkles, with no observed Tyndall effect. This technique shows promise for rejuvenating the skin in the horizontal neckline region.
    MeSH term(s) Adult ; Humans ; Female ; Polydioxanone ; Retrospective Studies ; Esthetics ; Skin ; Software
    Chemical Substances Polydioxanone (31621-87-1)
    Language English
    Publishing date 2024-02-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 1229160-2
    ISSN 1600-0846 ; 0909-752X ; 1397-1344
    ISSN (online) 1600-0846
    ISSN 0909-752X ; 1397-1344
    DOI 10.1111/srt.13617
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4278: Show issues Location:
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  3. Article ; Online: Commentary on: Anatomical Considerations for the Injection of Botulinum Neurotoxin in Shoulder and Arm Contouring.

    Cotofana, Sebastian / Knoedler, Samuel / Knoedler, Leonard / Alfertshofer, Michael G

    Aesthetic surgery journal

    2023  Volume 44, Issue 3, Page(s) 327–328

    MeSH term(s) Humans ; Shoulder ; Arm ; Botulinum Toxins, Type A ; Injections ; Upper Extremity
    Chemical Substances Botulinum Toxins, Type A (EC 3.4.24.69)
    Language English
    Publishing date 2023-09-22
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 2087022-X
    ISSN 1527-330X ; 1090-820X ; 1084-0761
    ISSN (online) 1527-330X
    ISSN 1090-820X ; 1084-0761
    DOI 10.1093/asj/sjad312
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    Zs.A 5721: Show issues Location:
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    Zs.MO 570: Show issues

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  4. Article ; Online: The Deep Columellar Approach for Liquid Rhinoplasty - A Case Series of 511 Procedures over 16 years.

    Magacho-Vieira, Fabiano Nadson / Alfertshofer, Michael G / Cotofana, Sebastian

    Facial plastic surgery clinics of North America

    2022  Volume 30, Issue 2, Page(s) 193–203

    Abstract: Injecting soft-tissue fillers in the nose requires a very specific approach, as vascular-related adverse events are a pivotal concern. This study describes a novel standardized 4-step treatment algorithm for safe, reproducible, and effective liquid ... ...

    Abstract Injecting soft-tissue fillers in the nose requires a very specific approach, as vascular-related adverse events are a pivotal concern. This study describes a novel standardized 4-step treatment algorithm for safe, reproducible, and effective liquid rhinoplasty procedures using a "deep columellar approach." Medical records of n = 511 treatments were retrospectively analyzed with respect to the occurrence and severity of adverse events. The low rate and severity reported for such incidents can be correlated to a precise and verifiable filler placement in the deep, supraperiosteal, and supraperichondrial layers, using blunt cannulas.
    MeSH term(s) Humans ; Nasal Septum ; Retrospective Studies ; Rhinoplasty/methods ; Skin
    Language English
    Publishing date 2022-02-23
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1315178-2
    ISSN 1558-1926 ; 1064-7406
    ISSN (online) 1558-1926
    ISSN 1064-7406
    DOI 10.1016/j.fsc.2022.01.005
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  5. Article ; Online: Clinical outcomes after lip injection procedures-Comparison of two hyaluronic acid gel fillers with different product properties.

    Hilton, Said / Frank, Konstantin / Alfertshofer, Michael / Cotofana, Sebastian

    Journal of cosmetic dermatology

    2022  Volume 22, Issue 1, Page(s) 119–127

    Abstract: Background: Transient swelling is common after lip injections with hyaluronic acid (HA) based fillers. Swelling and other injection-site reactions may relate to the injection procedure itself, or to gel properties, which differ between fillers due to ... ...

    Abstract Background: Transient swelling is common after lip injections with hyaluronic acid (HA) based fillers. Swelling and other injection-site reactions may relate to the injection procedure itself, or to gel properties, which differ between fillers due to differences in manufacturing methods.
    Objectives: To evaluate safety and effectiveness of lip injections with two HA fillers manufactured using different gel technologies.
    Methods: In a study sample of 40 subjects, treatment with two soft tissue filler product (HA
    Results: In subjects treated with HA
    Conclusions: The intensity of early-onset swelling, and other injection-site reactions was lower in subjects treated with HA
    MeSH term(s) Humans ; Cosmetic Techniques/adverse effects ; Dermal Fillers/adverse effects ; Edema/chemically induced ; Hyaluronic Acid/adverse effects ; Injection Site Reaction/etiology ; Injections/adverse effects ; Lip ; Pain/etiology ; Skin Aging ; Treatment Outcome
    Chemical Substances Dermal Fillers ; Hyaluronic Acid (9004-61-9)
    Language English
    Publishing date 2022-12-02
    Publishing country England
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 2280551-5
    ISSN 1473-2165 ; 1473-2130
    ISSN (online) 1473-2165
    ISSN 1473-2130
    DOI 10.1111/jocd.15548
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6539: Show issues Location:
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  6. Book ; Online ; Thesis: Multimodale Untersuchung der fazialen Gefäßtopographie in der Frontal- und Perioralregion

    Alfertshofer, Michael [Verfasser] / Schenck, Thilo [Akademischer Betreuer]

    2023  

    Author's details Michael Alfertshofer ; Betreuer: Thilo Schenck
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitätsbibliothek der Ludwig-Maximilians-Universität
    Publishing place München
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  7. Article ; Online: Introduction of the Lip Classification of Tubercles: A Novel Approach to Minimally Invasive Aesthetic Lip Treatments.

    Harris, Steven / Alfertshofer, Michael / Allen, Rory / Castellari, Fabrizio / Othoro, Don / Bran, Greg / Cotofana, Sebastian

    Aesthetic surgery journal. Open forum

    2023  Volume 5, Page(s) ojad007

    Language English
    Publishing date 2023-03-15
    Publishing country England
    Document type Journal Article
    ISSN 2631-4797
    ISSN (online) 2631-4797
    DOI 10.1093/asjof/ojad007
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  8. Article ; Online: Histological effects of a combined collagen stimulation procedure consisting of microfocused ultrasound, soft tissue filler, and Ca-HA injections.

    Casabona, Gabriela / Kaye, Kai / Cotofana, Sebastian / Davidovic, Kristina / Alfertshofer, Michael / Freytag, Lysander

    Journal of cosmetic dermatology

    2023  Volume 22, Issue 6, Page(s) 1724–1730

    Abstract: Background: An increasing demand for in-office aesthetic procedures aiming to improve collagen stimulation has been reported.: Objective: To analyze the effects of combinations of different aesthetic collagen stimulation procedures using histological ...

    Abstract Background: An increasing demand for in-office aesthetic procedures aiming to improve collagen stimulation has been reported.
    Objective: To analyze the effects of combinations of different aesthetic collagen stimulation procedures using histological analysis.
    Methods: Histological analysis was performed on skin samples of the excess skin of a 60-year-old patient after sub-superficial musculo-aponeurotic system facelift surgery. The excess skin before facelift surgery was divided into three areas per hemiface. Each area-with exception of area A as a control-received an isolated or combined treatment of microfocused ultrasound (MFU), injections of calcium-hydroxylapatite/hyaluronic-acid-based soft tissue filler, and microneedling. The effect of the treatments was analyzed using histological analysis with H&E coloration and PAS staining.
    Results: A threefold increase of epidermal and dermal thickness was achieved by treating the skin with the proposed combined treatment comprising MFU and injections of calcium-hydroxylapatite- and hyaluronic-acid-based soft tissue fillers.
    Conclusion: The investigated treatments act synergistically in the production of collagen and combining these treatments allows for an increase in collagen production.
    MeSH term(s) Humans ; Middle Aged ; Durapatite ; Calcium/pharmacology ; Skin ; Rhytidoplasty ; Collagen/pharmacology ; Hyaluronic Acid ; Dermal Fillers ; Skin Aging ; Cosmetic Techniques
    Chemical Substances Durapatite (91D9GV0Z28) ; Calcium (SY7Q814VUP) ; Collagen (9007-34-5) ; Hyaluronic Acid (9004-61-9) ; Dermal Fillers
    Language English
    Publishing date 2023-04-18
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2280551-5
    ISSN 1473-2165 ; 1473-2130
    ISSN (online) 1473-2165
    ISSN 1473-2130
    DOI 10.1111/jocd.15770
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6539: Show issues Location:
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  9. Article ; Online: Is constant needle motion during soft tissue filler injections a safer procedure? A theoretical mathematical model for evaluating patient safety.

    Gonchar, Ivan V / Alfertshofer, Michael / Nikolis, Andreas / Hong, Wei-Jin / Biesman, Brian / Cotofana, Sebastian

    Journal of cosmetic dermatology

    2023  Volume 22, Issue 11, Page(s) 2964–2970

    Abstract: Background: The safety rationale behind the constant needle motion injection technique is based on the assumption that due to the constant needle motion and simultaneous soft tissue filler material administration a smaller amount of product per area may ...

    Abstract Background: The safety rationale behind the constant needle motion injection technique is based on the assumption that due to the constant needle motion and simultaneous soft tissue filler material administration a smaller amount of product per area may be injected into an artery if an artery within the range of the moving needle is inadvertently entered.
    Objective: To perform mathematical calculations for determining the probability for causing intra-arterial product administration when constantly moving the needle during facial aesthetic soft tissue filler injections.
    Methods: This study was designed as a theoretical investigation into the probabilities for causing adverse events due to intravascular injection of soft tissue filler material when constantly moving a 27-G needle during facial soft tissue filler administration.
    Results: It was revealed that with a higher number of conducted injection passes a greater soft tissue area can be covered by the needle. The odds of encountering an artery within the covered soft tissue volume and the odds of injecting any volume greater than zero into the arterial blood stream increases with the number of performed injection passes. This increase is greatest between 1 and 10 performed injection passes.
    Conclusion: This model demonstrates that the constant needle motion technique increases the probability of encountering an artery within the treatment area and thus increases the odds for intra-arterial product administration. The constant needle motion technique does not increase safety but rather may increase the odds of causing intra-arterial product administration with the respective adverse consequences for the patient.
    Language English
    Publishing date 2023-09-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 2280551-5
    ISSN 1473-2165 ; 1473-2130
    ISSN (online) 1473-2165
    ISSN 1473-2130
    DOI 10.1111/jocd.15998
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    Zs.A 6539: Show issues Location:
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  10. Article ; Online: Commentary on: The Dorsal Nasal Complex in Asians: Anatomical Variations and Injection Guide for Botulinum Toxin Type A.

    Cotofana, Sebastian / Alfertshofer, Michael G / Frank, Konstantin / Freytag, Lysander / Moellhoff, Nicholas

    Aesthetic surgery journal

    2023  Volume 43, Issue 7, Page(s) 771–772

    MeSH term(s) Humans ; Botulinum Toxins, Type A ; Asian ; Nose ; Injections
    Chemical Substances Botulinum Toxins, Type A (EC 3.4.24.69)
    Language English
    Publishing date 2023-04-05
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 2087022-X
    ISSN 1527-330X ; 1090-820X ; 1084-0761
    ISSN (online) 1527-330X
    ISSN 1090-820X ; 1084-0761
    DOI 10.1093/asj/sjad091
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5721: Show issues Location:
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