LIVIVO - Search results -

Search results

Result 1 - 10 of total 21

Search options

Article ; Online: Combining Molecular Quantum Mechanical Modeling and Machine Learning for Accelerated Reaction Screening and Discovery.

Casetti, Nicholas / Alfonso-Ramos, Javier E / Coley, Connor W / Stuyver, Thijs

Chemistry (Weinheim an der Bergstrasse, Germany)

2023 Volume 29, Issue 60, Page(s) e202301957

Abstract: Molecular quantum mechanical modeling, accelerated by machine learning, has opened the door to high-throughput screening campaigns of complex properties, such as the activation energies of chemical reactions and absorption/emission spectra of materials ... ...

Abstract	Molecular quantum mechanical modeling, accelerated by machine learning, has opened the door to high-throughput screening campaigns of complex properties, such as the activation energies of chemical reactions and absorption/emission spectra of materials and molecules; in silico. Here, we present an overview of the main principles, concepts, and design considerations involved in such hybrid computational quantum chemistry/machine learning screening workflows, with a special emphasis on some recent examples of their successful application. We end with a brief outlook of further advances that will benefit the field.
Language	English
Publishing date	2023-09-14
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1478547-X
ISSN	1521-3765 ; 0947-6539
ISSN (online)	1521-3765
ISSN	0947-6539
DOI	10.1002/chem.202301957
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- Full text online
- Order with fees

Article ; Online: Is epilepsy related to psychiatric disorders in people with intellectual disability? A systematic review.

Peña-Salazar, Carlos / Alfonso-Ramos, Miqueu / Arroyo-Uriarte, Paula / Serrano-Blanco, Antoni / Aznar-Lou, Ignacio

Journal of intellectual disabilities : JOID

2022 , Page(s) 17446295221116506

Abstract: The prevalence of psychiatric disorders in people with Intellectual Disability (ID) is statistically higher than in the general population. There is a lack of consensus on the role that epilepsy plays in psychiatric disorders in people with ID. We ... ...

Abstract	The prevalence of psychiatric disorders in people with Intellectual Disability (ID) is statistically higher than in the general population. There is a lack of consensus on the role that epilepsy plays in psychiatric disorders in people with ID. We carried out a systematic review of articles published between 1960 and 2022, focusing on high-quality, case-control original research studies that only included adult populations. The primary outcome was the prevalence of psychiatric disorders in people with intellectual disability with and without epilepsy. Six articles were finally included. Results were varied; some reported a statistical increase, whereas others did not find any statistical difference. Due to the current controversy on the role of epilepsy in psychiatric disorders in people with ID and the small number of publications on the topic, we cannot affirm a relationship between epilepsy and psychiatric disorders in people with ID.
Language	English
Publishing date	2022-08-04
Publishing country	England
Document type	Journal Article
ZDB-ID	2071898-6
ISSN	1744-6309 ; 1469-0047 ; 1744-6295
ISSN (online)	1744-6309
ISSN	1469-0047 ; 1744-6295
DOI	10.1177/17446295221116506
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Turismo deportivo

Pedro Alfonso Ramos Sanchez / Amgelica Ruth Terrazas Juarez

Expresión Económica, Iss 42, Pp 79-

Consideraciones conceptuales y actores para fomentar el desarrollo territorial en destinos turísticos

2019 Volume 97

Abstract: Este trabajo se centra en describir el turismo deportivo desde sus antecedentes y relevancia, como herramienta para el desarrollo. Mediante un estudio exploratorio, la investigación documental permitió la descripción histórica de la evolución del turismo ...

Abstract	Este trabajo se centra en describir el turismo deportivo desde sus antecedentes y relevancia, como herramienta para el desarrollo. Mediante un estudio exploratorio, la investigación documental permitió la descripción histórica de la evolución del turismo deportivo y de su importancia en el contexto mundial y nacional; se analizaron conceptos de turismo deportivo y se propuso un concepto propio que considera la orientación aplicada al desarrollo; todo esto, mediante la utilización de metodología de la Organización Internacional de Estandarización, iso 10241, y recomendaciones para la redacción de definiciones. También se identificaron los actores involucrados, así como su importancia para fomentar el desarrollo territorial en los destinos. Las principales conclusiones apuntan a destacar la importancia de esta actividad para generar desarrollo.
Keywords	sports ; gambling ; restaurants ; recreation ; tourism ; Economic history and conditions ; HC10-1085 ; Finance ; HG1-9999 ; Economics as a science ; HB71-74
Language	English
Publishing date	2019-05-01T00:00:00Z
Publisher	Universidad de Guadalajara
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Remote monitoring as a surveillance method in patients on automated peritoneal dialysis for preventing complications and COVID-19 contagion

Miguel A. Cuevas-Budhart / Miguel A. Trejo-Villeda / Miriam Cabrera Delgado / Beatriz Hernandez-Franco / Marcela Ávila Díaz / Alfonso Ramos-Sanchez / Ramón Paniagua

Journal of Infection and Public Health, Vol 16, Iss 10, Pp 1619-

2023 Volume 1624

Abstract: Background: Due to the health emergency of COVID-19, telemedicine has become more relevant. Remote monitoring conspicuous as a valuable tool for the clinical follow-up of kidney patients, in this case, who are treated with automated peritoneal dialysis. ... ...

Abstract	Background: Due to the health emergency of COVID-19, telemedicine has become more relevant. Remote monitoring conspicuous as a valuable tool for the clinical follow-up of kidney patients, in this case, who are treated with automated peritoneal dialysis. This study aims to describe the use of remote monitoring as a surveillance method in a cohort of patients on automated peritoneal dialysis prevent complications and COVID-19 contagion. Methods: Study of a cohort of patients who initially participated in a randomized block clinical trial in which the use of Automated Peritoneal Dialysis with Remote Monitoring (APD-RM) was compared with conventional treatment. A descriptive analysis was performed of the rates of infection by COVID-19, the time of incidence until this, mortality, and rates of transfer to hemodialysis. In addition, survival was measured by survival curves. Results: Of the 509 patients, 19 were positive for COVID-19 (incidence rate of 7.0 episodes/100 patient-year), and only six patients recovered from the infection; the death rate was 2.6 % compared to all-cause death of 9.8 %. The most affected group of patients were those over 50 years old, with 71.4 % mortality, in contrast to younger patients infected, with a mortality of 60 %. During the follow-up period, 21 patients were transferred to HD: six due to peritonitis, five due to UF failure, seven due to catheter dysfunction, one due to uremic syndrome, one due to COVID-19, and one by surgical intervention. Conclusion: APD-RM patients have a significant advantage over other dialysis therapies because the use of telemedicine not only provides continuity in the patient's clinical treatment but also favors the prevention of COVID-19 infection, the management and prevention of complications inherent to therapy and the preservation of the life of Peritoneal Dialysis patients.
Keywords	Covid-19 ; Automated peritoneal dialysis ; Telemedicine ; Remote Monitoring ; Infectious and parasitic diseases ; RC109-216 ; Public aspects of medicine ; RA1-1270
Subject code	616 ; 610
Language	English
Publishing date	2023-10-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Combination with Annual Deworming Treatments Does Not Enhance the Effects of PCV2 Vaccination on the Development of TB in Wild Boar Populations

Javier Galapero / Alfonso Ramos / José Manuel Benítez-Medina / Remigio Martínez / Alfredo García / Javier Hermoso de Mendoza / Rocío Holgado-Martín / David Risco / Luis Gómez

Animals, Vol 13, Iss 24, p

2023 Volume 3833

Abstract: Vaccination against PCV2 has been proven to be an effective measure to reduce the severity of TB in wild boar. The combination of this measure with strategies focused on treating other key concomitant pathogens, such as nematodes, could be a useful ... ...

Abstract	Vaccination against PCV2 has been proven to be an effective measure to reduce the severity of TB in wild boar. The combination of this measure with strategies focused on treating other key concomitant pathogens, such as nematodes, could be a useful strategy. This study assesses whether a combination of deworming treatments and PCV2 vaccination may reduce the prevalence and severity of TB in wild boar. The study was conducted on five game estates in mid-western Spain where four groups of wild boar were produced: control, vaccinated, dewormed and vaccinated-dewormed. Wild boars from all groups were hunted between 2017 and 2020, and all of them received a TB diagnosis based on pathological and microbiological tests. Generalised linear models were used to explore the effect of deworming and PCV2 vaccination on TB prevalence and severity. PCV2-vaccinated animals showed lower probabilities of suffering severe TB lesions. However, no differences regarding TB severity were found between dewormed and non-dewormed wild boar. PCV2 vaccination reduces TB severity in wild boar. However, annual deworming does not produce a long-term parasitological reduction that can influence the development of TB in wild boar, nor does it improve the effect of PCV2 vaccination on TB.
Keywords	tuberculosis ; wild boar ; porcine circovirus ; deworming ; vaccination ; Veterinary medicine ; SF600-1100 ; Zoology ; QL1-991
Subject code	630
Language	English
Publishing date	2023-12-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Statistical inference in two-sex biological populations with reproduction in a random environment

Molina, Manuel / Alfonso Ramos / Manuel Mota

Ecological complexity. 2017 June, v. 30

2017

Abstract: We mathematically model the demographic dynamics of biological populations with sexual reproduction where mating and reproduction can be influenced by the current number of couples in the population. We assume the more realistic situation where the ... ...

Abstract	We mathematically model the demographic dynamics of biological populations with sexual reproduction where mating and reproduction can be influenced by the current number of couples in the population. We assume the more realistic situation where the reproduction process occurs in a non-predictable environment. We also consider the immigration/emigration of couples in the population. In this work, we continue the research about the class of two-sex models introduced in Ma et al. (2016) where the offspring distribution changes over time in a random environment influenced by the number of progenitor couples in the population. By considering the more general non-parametric statistical setting, we study several inferential problems of ecological interest. As illustration, we present an application to Pacific salmon populations.
Keywords	immigration ; models ; progeny ; salmon ; sexual reproduction
Language	English
Dates of publication	2017-06
Size	p. 63-69.
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	2160288-8
ISSN	1476-945X
ISSN	1476-945X
DOI	10.1016/j.ecocom.2016.09.005
Database	NAL-Catalogue (AGRICOLA)

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Bonn / Germany

Z 7555: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

Article ; Online: Peritoneal dialysis modality transition and impact on phosphate and potassium serum levels.

Daniela Peruzzo / Murilo Guedes / John W Larkin / Guilherme Yokoyama / Taynara Lopes Dos Santos / Roberto Pecoits-Filho / Silvia Carreira Ribeiro / Alfonso Ramos / Pasqual Barretti / Thyago Proença de Moraes / BRAZPD Investigators

PLoS ONE, Vol 16, Iss 10, p e

2021 Volume 0257140

Abstract: Peritoneal dialysis (PD) modalities affect solute removal differently. However, the impacts of switching PD modalities on serum levels of biomarkers of different sizes are not known. Our objective was to analyze whether a change in the PD modality ... ...

Abstract	Peritoneal dialysis (PD) modalities affect solute removal differently. However, the impacts of switching PD modalities on serum levels of biomarkers of different sizes are not known. Our objective was to analyze whether a change in the PD modality associates with the levels of two routine biochemical laboratories. In this multicentric prospective cohort study. we selected all patients who remained on a PD modality for at least 6 months and switched PD modality. Patients were also required to be treated with the same PD modality for at least 3 months before and after the modality change. The primary outcome was change in potassium and phosphate serum levels. We identified 737 eligible patients who switched their PD modality during the study. We found mean serum phosphate levels increased during the 3 months after switching from CAPD to APD and conversely decreased after switching to from APD to CAPD. In contrast, for potassium the difference in the mean serum levels was comparable between groups switching from CAPD to APD, and vice versa. In conclusion, CAPD seems to be as efficient as APD for the control of potassium serum levels, but more effective for the control of phosphate serum levels. The effect of a higher removal of middle size molecules as result of PD modalities in terms of clinical and patient-reported outcomes should be further explored.
Keywords	Medicine ; R ; Science ; Q
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Pulmonary Hypertension in Patients Starting Peritoneal Dialysis.

Orihuela, Oscar / de Jesus Ventura, Ma / Carmona-Ruiz, Héctor A / Santos-Martinez, Luis-Efren / Sánchez, Alfonso Ramos / Paniagua, Ramon

Archives of medical research

2020 Volume 51, Issue 3, Page(s) 254–260

Abstract: Background: Cardiovascular complications are the major cause of morbidity and mortality in patients with chronic kidney disease (CKD). One such complication is pulmonary hypertension (PH). Its prevalence in patients in peritoneal dialysis (PD) varies ... ...

Abstract	Background: Cardiovascular complications are the major cause of morbidity and mortality in patients with chronic kidney disease (CKD). One such complication is pulmonary hypertension (PH). Its prevalence in patients in peritoneal dialysis (PD) varies from 12.6-41.7% and its related factors are not well known. The main objective of this multicenter study was to determine the prevalence of PH and its risk factors in patients starting in PD. Methods: Patients incident in PD were studied. Clinical, biochemical, and PD parameters were evaluated. A transthoracic echocardiography was performed and the evaluated according to the American Society of Echocardiography. Systolic pulmonary artery pressure (sPAP) was calculated with tricuspid regurgitation gradient and PH considered if pulmonary artery pressure was ≥35 mmHg. Results: There were 105 men and 72 women included in the study (aged 53.7 ± 12.8 vs. 52.9 ± 15.5 years). PH was found in 69 patients (38.98%), they had sPAP of 49.05 ± 13.80 vs. 18.81 ± 11.15 mmg, in patients without PH (p <0.001). Patients with PH tend to be more frequently men than women (42 vs. 35%, p = 0.33), and were younger (51.0 ± 14.9 vs. 55,1 ± 12.8 years; p = 0.05). Risk factor for PH were diastolic dysfunction of the left ventricle (LV) (OR = 1.46, 95% CI 1.094-1.973), left ventricular hypertrophy (LVF) (OR = 2.56, 95% CI 1.29-5.09); and residual renal function (RRF) was a protector factor (OR = 0.78, 95% CI 0.068-0.915). Conclusions: Prevalence of PH in patient's incident in PD was 38%. The factors associated with PH were diastolic dysfunction of the LV and LV hypertrophy. RRF was a protector factor.
MeSH term(s)	Blood Pressure/physiology ; Echocardiography/adverse effects ; Female ; Heart Ventricles/pathology ; Humans ; Hypertension, Pulmonary/complications ; Hypertension, Pulmonary/epidemiology ; Hypertension, Pulmonary/etiology ; Hypertrophy, Left Ventricular/pathology ; Kidney/pathology ; Male ; Middle Aged ; Peritoneal Dialysis/statistics & numerical data ; Prevalence ; Pulmonary Artery/physiology ; Renal Insufficiency, Chronic/complications ; Renal Insufficiency, Chronic/therapy ; Risk Factors
Language	English
Publishing date	2020-02-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	1156844-6
ISSN	1873-5487 ; 0188-4409 ; 0188-0128
ISSN (online)	1873-5487
ISSN	0188-4409 ; 0188-0128
DOI	10.1016/j.arcmed.2020.02.004
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.B 1001: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Peritoneal dialysis modality transition and impact on phosphate and potassium serum levels

Daniela Peruzzo / Murilo Guedes / John W. Larkin / Guilherme Yokoyama / Taynara Lopes dos Santos / Roberto Pecoits-Filho / Silvia Carreira Ribeiro / Alfonso Ramos / Pasqual Barretti / Thyago Proença de Moraes / on behalf of the BRAZPD Investigators

PLoS ONE, Vol 16, Iss

2021 Volume 10

Abstract	Peritoneal dialysis (PD) modalities affect solute removal differently. However, the impacts of switching PD modalities on serum levels of biomarkers of different sizes are not known. Our objective was to analyze whether a change in the PD modality associates with the levels of two routine biochemical laboratories. In this multicentric prospective cohort study. we selected all patients who remained on a PD modality for at least 6 months and switched PD modality. Patients were also required to be treated with the same PD modality for at least 3 months before and after the modality change. The primary outcome was change in potassium and phosphate serum levels. We identified 737 eligible patients who switched their PD modality during the study. We found mean serum phosphate levels increased during the 3 months after switching from CAPD to APD and conversely decreased after switching to from APD to CAPD. In contrast, for potassium the difference in the mean serum levels was comparable between groups switching from CAPD to APD, and vice versa. In conclusion, CAPD seems to be as efficient as APD for the control of potassium serum levels, but more effective for the control of phosphate serum levels. The effect of a higher removal of middle size molecules as result of PD modalities in terms of clinical and patient-reported outcomes should be further explored.
Keywords	Medicine ; R ; Science ; Q
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Pituitary macroadenoma apoplexy in a severe acute respiratory syndrome-coronavirus-2-positive testing: Causal or casual?

Solorio-Pineda, Saúl Almendárez-Sánchez César Adán Tafur-Grandett / Abrahan Alfonso, Ramos-Martínez Gabriel Arturo / Huato-Reyes, Raúl Ruiz-Flores / Milton Inocencio, Sosa-Najera / Antonio,

Surgical Neurology International

Abstract: Background: In December 2019, in Wuhan, a new virus emerged, causing severe acute respiratory syndrome (SARS) secondary to infection by a type of coronavirus, causing coronavirus disease (COVID-19) The pandemic caused by the new coronavirus has had ... ...

Abstract	Background: In December 2019, in Wuhan, a new virus emerged, causing severe acute respiratory syndrome (SARS) secondary to infection by a type of coronavirus, causing coronavirus disease (COVID-19) The pandemic caused by the new coronavirus has had implications in the central nervous system COVID-19 is known to be characterized by coagulation activation and endothelial dysfunction, causing ischemic and hemorrhagic vascular syndromes Case Description: A 27-year-old male patient case with progressive decrease in visual acuity, associated with respiratory symptoms and intense headache Multilobar infiltrate with a reticulonodular pattern is evident on chest CT scan Brain CT scan with pituitary macroadenoma apoplexy was shown SARS-Cov2 was confirmed, and respiratory support initiated However, the patient died shortly afterward, secondary to pulmonary complications Conclusion: The angiotensin-converting enzyme (ACE) II receptor is expressed in circumventricular organs and in cerebrovascular endothelial cells, which play a role in vascular autoregulation and cerebral blood flow For this reason, is rational the hypothesize that brain ACE II could be involved in COVID-19 infection Underlying mechanisms require further elucidation in the future [ABSTRACT FROM AUTHOR] Copyright of Surgical Neurology International is the property of Scientific Scholar LLC and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission However, users may print, download, or email articles for individual use This abstract may be abridged No warranty is given about the accuracy of the copy Users should refer to the original published version of the material for the full abstract (Copyright applies to all Abstracts )
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #831631
Database	COVID19

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

To top

Full text online

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Kategorien

Inter-library loan at ZB MED