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  1. Article ; Online: Situación actual y perspectivas de la Comunidad Andina

    Alfredo Fuentes

    OASIS, Iss

    2007  Volume 12

    Abstract: La Comunidad Andina de Naciones ha presentado avances particularmente importantes en lo que respecta al comercio de bienes y servicios, y la creación de un patrimonio institucional y jurídico sólido. En cuanto a la libre movilidad de personas y de ... ...

    Abstract La Comunidad Andina de Naciones ha presentado avances particularmente importantes en lo que respecta al comercio de bienes y servicios, y la creación de un patrimonio institucional y jurídico sólido. En cuanto a la libre movilidad de personas y de capitales los avances han sido significativos, pero aún persiste la necesidad de redactar un estatuto común que favorezca en especial el movimiento de capitales. A pesar del retiro de Venezuela, las perspectivas son alentadoras: los efectos de tal situación han sido atenuados por las disposiciones del artículo 135 del Acuerdo de Cartagena. Por otro lado, los avances en la concertación política con la Unión Europea y la manifestación del interés de Chile de volver a la Comunidad Andina
    Keywords Unión Europea ; Comunidad Andina de Naciones ; sistema jurídico ; orden legal ; Political science ; J ; International relations ; JZ2-6530
    Language English
    Publishing date 2007-11-01T00:00:00Z
    Publisher Universidad Externado de Colombia
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Contexto histórico y avances de la integración en la Comunidad Andina

    Alfredo Fuentes Fernández

    OASIS, Iss

    2008  Volume 13

    Abstract: Este artículo aborda el tema de la integración económica, política y social de los países que integran la Comunidad Andina y de las vicisitudes que se han vivido desde que se adoptó el Acuerdo de Cartagena en 1969. Se hace un análisis de las cambiantes ... ...

    Abstract Este artículo aborda el tema de la integración económica, política y social de los países que integran la Comunidad Andina y de las vicisitudes que se han vivido desde que se adoptó el Acuerdo de Cartagena en 1969. Se hace un análisis de las cambiantes concepciones sobre el desarrollo y de la inserción internacional de las economías andinas durante estos años y como ellas han incidido en los cambios de la Comunidad y de cada uno de los países miembros. Así, es interesante tener en cuenta esos modelos de integración que en principio se basaron en la sustitución subregional, que enfatizó en la promoción deliberada de la industrialización, frente a las frustraciones derivadas de la distribución inequitativa de los beneficios obtenidos bajo el esquema de la Asociación Latinoamericana de Libre Comercio, alac. Luego veremos cómo estos países se adaptan a los cambios en las políticas nacionales y en las transformaciones de la economía internacional.
    Keywords Comunidad Andina ; alalc ; integración ; apertura ; Acuerdo de Cartagena ; desarrollo ; Political science ; J ; International relations ; JZ2-6530
    Language English
    Publishing date 2008-11-01T00:00:00Z
    Publisher Universidad Externado de Colombia
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: N -Heterocycles Scaffolds as Quorum Sensing Inhibitors. Design, Synthesis, Biological and Docking Studies

    Alfredo Fuentes-Gutiérrez / Everardo Curiel-Quesada / José Correa-Basurto / Alberto Martínez-Muñoz / Alicia Reyes-Arellano

    International Journal of Molecular Sciences, Vol 21, Iss 9512, p

    2020  Volume 9512

    Abstract: Quorum sensing is a communication system among bacteria to sense the proper time to express their virulence factors. Quorum sensing inhibition is a therapeutic strategy to block bacterial mechanisms of virulence. The aim of this study was to synthesize ... ...

    Abstract Quorum sensing is a communication system among bacteria to sense the proper time to express their virulence factors. Quorum sensing inhibition is a therapeutic strategy to block bacterial mechanisms of virulence. The aim of this study was to synthesize and evaluate new bioisosteres of N -acyl homoserine lactones as Quorum sensing inhibitors in Chromobacterium violaceum CV026 by quantifying the specific production of violacein. Five series of compounds with different heterocyclic scaffolds were synthesized in good yields: thiazoles, 16a – c , thiazolines 17a – c , benzimidazoles 18a – c , pyridines 19a – c and imidazolines 32a – c . All 15 compounds showed activity as Quorum sensing inhibitors except 16a . Compounds 16b , 17a – c , 18a , 18c , 19c and 32b exhibited activity at concentrations of 10 µM and 100 µM, highlighting the activity of benzimidazole 18a (IC 50 = 36.67 µM) and 32b (IC 50 = 85.03 µM). Pyridine 19c displayed the best quorum sensing inhibition activity (IC 50 = 9.66 µM). Molecular docking simulations were conducted for all test compounds on the Chromobacterium violaceum CviR protein to gain insight into the process of quorum sensing inhibition. The in-silico data reveal that all 15 the compounds have higher affinity for the protein than the native AHL ligand ( 1 ). A strong correlation was found between the theoretical and experimental results.
    Keywords heterocycles synthesis ; new AHL bioisosteres ; π–π interactions ; quorum sensing ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
    Subject code 540
    Language English
    Publishing date 2020-12-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: The role of niche overlap, environmental heterogeneity, landscape roughness and productivity in shaping species abundance distributions along the Amazon–Andes gradient

    Arellano, Gabriel / María N. Umaña / Manuel J. Macía / M. Isabel Loza / Alfredo Fuentes / Victoria Cala / Peter M. Jørgensen

    Global ecology and biogeography. 2017 Feb., v. 26, no. 2

    2017  

    Abstract: AIM: Statistical and ecological mechanisms shape species abundance distributions (SADs). A lack of correlation between ecological gradients and SAD shape would suggest that SADs are caused by purely statistical reasons. We evaluated the variation in the ... ...

    Abstract AIM: Statistical and ecological mechanisms shape species abundance distributions (SADs). A lack of correlation between ecological gradients and SAD shape would suggest that SADs are caused by purely statistical reasons. We evaluated the variation in the shape of SADs for communities in landscapes of differing variable connectivity, environmental heterogeneity, species niches overlap and productivity. LOCATION: Rainforests in the Madidi region (Bolivia). METHODS: We compiled biological and environmental information on 65 sites (a site being a group of two to six 0.1‐ha plots where woody plants of a diameter at breast height ≥ 2.5 cm were inventoried). We built unveiled (complete) SADs for each site and fitted Gambin models to those SADs. The Gambin α parameter served as a metric of SAD shape. Low α values characterize logseries‐like SADs, while high α values characterize lognormal‐like SADs. For each site, we estimated landscape roughness, environmental heterogeneity, species niche overlap and productivity. These variables were related to SAD shape by means of variation partitioning. RESULTS: SADs changed from logseries‐like to lognormal‐like along the elevational gradient. Many of our predictor variables were correlated: 40.4% of the variation in SAD shape could not be attributed to specific factors. However, 50.62% of the variation in the SAD shape could be assigned to individual predictor matrices: 28.4% was explained exclusively by niche overlap, 15.41% exclusively by environmental heterogeneity, 5.20% exclusively by landscape roughness and 1.6% exclusively by productivity. MAIN CONCLUSIONS: Ecological processes related to the topographical/environmental complexities that vary across the elevational gradient are correlated with the SAD shape. Purely statistical mechanisms are apparently not sufficient to explain the changes in SAD shape. The most important factor is the mean overlap of the niches of the species of an assemblage: avoiding competition with co‐occurring species could be the most important mechanism driving species relative success at the ≤100 km² scale.
    Keywords landscapes ; models ; niches ; rain forests ; roughness ; tree and stand measurements ; woody plants ; Bolivia
    Language English
    Dates of publication 2017-02
    Size p. 191-202.
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note JOURNAL ARTICLE
    ZDB-ID 2021283-5
    ISSN 1466-8238 ; 1466-822X ; 0960-7447
    ISSN (online) 1466-8238
    ISSN 1466-822X ; 0960-7447
    DOI 10.1111/geb.12531
    Database NAL-Catalogue (AGRICOLA)

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  5. Article ; Online: Presentación atípica de piomiositis tropical difusa de psoas por Staphylococcus aureus meticilino resistente Atypical presentation of diffuse tropical pyomiositis of the psoas due to methicillin resistant Staphylococcus aureus

    Ray Ticse / Weymar Melgarejo / Alfredo Fuentes-Dávila / Jesús Ortíz / Jaime Zegarra

    Revista Peruana de Medicina Experimental y Salud Pública, Vol 29, Iss 1, Pp 135-

    2012  Volume 138

    Abstract: La piomiositis tropical difusa primaria es una enfermedad de presentación infrecuente en nuestro medio, con pocos casos asociados a Staphylococcus aureus meticilino resistente, adquirido en la comunidad (MRSA-AC). Se presenta el caso de un paciente de 70 ...

    Abstract La piomiositis tropical difusa primaria es una enfermedad de presentación infrecuente en nuestro medio, con pocos casos asociados a Staphylococcus aureus meticilino resistente, adquirido en la comunidad (MRSA-AC). Se presenta el caso de un paciente de 70 años, con tratamiento irregular para diabetes mellitus tipo 2, que fue hospitalizado por presentar un cuadro de diez días de evolución, con dolor lumbar irradiado a miembro inferior izquierdo, fiebre y flexión forzada de la cadera derecha por dolor a la movilización. El diagnóstico de piomiositis difusa de ambos psoas se realizó con resonancia magnética. Del cultivo de una colección paravertebral posterior se aisló Staphylococcus aureus resistente a oxacilina, penicilina y dicloxacilina. Diffuse tropical primary pyomyositis is an infrequent entity in our country, with few cases associated to communityacquired Methicillin- resistant Staphylococcus aureus. There are no reported cases of Community-Acquired Methicillin- Resistant Staphylococcus aureus (CA- MRSA) in Peru. We present the case of a 70 year old male with a previous diagnosis of type 2 diabetes mellitus, receiving irregular treatment, who was admitted to the hospital with a history of 10 days of low back pain radiating to the left leg, fever and forced flexion of the right hip due to pain during movement. The diagnosis of diffuse pyomyositis of both psoas muscles was performed with MRI and culture of a posterior paravertebral collection, from which Staphylococcus aureus resistant to oxacillin, penicillin and dicloxacillin was isolated.
    Keywords Piomiositis ; Músculos psoas ; Diabetes mellitus ; Staphylococcus aureus resistente a meticilina ; Pyomyositis ; Psoas muscles ; Methicillin-resistant Staphylococcus aureus ; Medicine ; R ; Medicine (General) ; R5-920
    Language Spanish
    Publishing date 2012-03-01T00:00:00Z
    Publisher Instituto Nacional de Salud
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Mature Andean forests as globally important carbon sinks and future carbon refuges

    Alvaro Duque / Miguel A. Peña / Francisco Cuesta / Sebastián González-Caro / Peter Kennedy / Oliver L. Phillips / Marco Calderón-Loor / Cecilia Blundo / Julieta Carilla / Leslie Cayola / William Farfán-Ríos / Alfredo Fuentes / Ricardo Grau / Jürgen Homeier / María I. Loza-Rivera / Yadvinder Malhi / Agustina Malizia / Lucio Malizia / Johanna A. Martínez-Villa /
    Jonathan A. Myers / Oriana Osinaga-Acosta / Manuel Peralvo / Esteban Pinto / Sassan Saatchi / Miles Silman / J. Sebastián Tello / Andrea Terán-Valdez / Kenneth J. Feeley

    Nature Communications, Vol 12, Iss 1, Pp 1-

    2021  Volume 10

    Abstract: Here, the authors investigate the aboveground carbon sink efficiency of Andean forests. The study shows the high potential of these forests to serve as future carbon refuges, and urges to reduce deforestation and increase restoration. ...

    Abstract Here, the authors investigate the aboveground carbon sink efficiency of Andean forests. The study shows the high potential of these forests to serve as future carbon refuges, and urges to reduce deforestation and increase restoration.
    Keywords Science ; Q
    Language English
    Publishing date 2021-04-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Author Correction

    Alvaro Duque / Miguel A. Peña / Francisco Cuesta / Sebastián González-Caro / Peter Kennedy / Oliver L. Phillips / Marco Calderón-Loor / Cecilia Blundo / Julieta Carilla / Leslie Cayola / William Farfán-Ríos / Alfredo Fuentes / Ricardo Grau / Jürgen Homeier / María I. Loza-Rivera / Yadvinder Malhi / Agustina Malizia / Lucio Malizia / Johanna A. Martínez-Villa /
    Jonathan A. Myers / Oriana Osinaga-Acosta / Manuel Peralvo / Esteban Pinto / Sassan Saatchi / Miles Silman / J. Sebastián Tello / Andrea Terán-Valdez / Kenneth J. Feeley

    Nature Communications, Vol 12, Iss 1, Pp 1-

    Mature Andean forests as globally important carbon sinks and future carbon refuges

    2021  Volume 1

    Keywords Science ; Q
    Language English
    Publishing date 2021-06-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Ecología, tecnología e innovación para la sustentabilidad: retos y perspectivas en México

    Gavito, Mayra E / Aída Atenea Bullén / Alejandro Casas-Fernández / Alfredo Fuentes / Bárbara Ayala-Orozco / Carlos González-Esquivel / Diego R. Pérez-Salicrup / E. Miriam Aldasoro / Fermín Pascual / Gilberto Villanueva / Hans van der Wal / Ilse Ruiz-Mercado / Manuel Cach-Pérez / Omar Masera-Cerruti / Pablo Jaramillo-López / Pablo Martínez / Ramiro Robles

    Universidad Nacional Autónoma de México, Instituto de Biología Revista mexicana de biodiversidad. 2017 Dec., v. 88

    2017  

    Abstract: In Mexico and in the world, the incorporation of the scientific community (among them ecologists) to the generation of knowledge that contributes to solving the serious environmental problems, and advancing towards the sustainability, requires a ... ...

    Abstract In Mexico and in the world, the incorporation of the scientific community (among them ecologists) to the generation of knowledge that contributes to solving the serious environmental problems, and advancing towards the sustainability, requires a different research vision. Moreover, innovative tools are needed to couple the work of the scientific community with the rest of the society. Ecologists are challenged to become innovators and creators of new models, collaborative processes, methods and research tools, basic and applied, in topics such as agriculture, forestry, livestock and the use of natural resources. To meet this challenge, ecologists in Mexico need to amalgamate their work with other academic and non-academic actors to jointly promote environmental improvement processes with social benefits. This contribution examines challenges and perspectives of ecotechnological innovation in Mexico. We suggest to foster the research work in this field in laboratories without walls, in which flexible groups of actors design, test, and evaluate ecotechnological innovations that respond to specific local and regional socio-ecological and environmental problems.
    Keywords ecologists ; forestry ; livestock ; models ; natural resources ; social benefit ; society ; vision ; Mexico
    Language English
    Dates of publication 2017-12
    Size p. 150-160.
    Publishing place Elsevier España, S.L.U.
    Document type Article
    ZDB-ID 2230783-7
    ISSN 1870-3453
    ISSN 1870-3453
    DOI 10.1016/j.rmb.2017.09.001
    Database NAL-Catalogue (AGRICOLA)

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  9. Article ; Online: El Pacto Andino

    Alfredo Fuentes Hernández. / María Mercedes de Martínez.

    Colombia Internacional, Iss 12, Pp 10-

    Hacia un nuevo modelo de integración.

    1990  Volume 20

    Keywords International relations ; JZ2-6530 ; Political science (General) ; JA1-92
    Language English
    Publishing date 1990-10-01T00:00:00Z
    Publisher Universidad de los Andes
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Mal de Pott en niños

    Patricia Campos / Eduardo Chaparro / Federico Valença / Alfredo Fuentes-Davila

    Arquivos de Neuro-Psiquiatria, Vol 47, Iss 3, Pp 303-

    1989  Volume 307

    Abstract: Se presentan 27 casos de mal de Pott en niños entre 6 meses y 14 años de edad vistos durante un período de 2 años con tiempo de seguimiento hasta de 18 meses, 67% menores de 6 años y de ellos 2 pacientes menores de 1 año. Hubo predominio de pacientes de ... ...

    Abstract Se presentan 27 casos de mal de Pott en niños entre 6 meses y 14 años de edad vistos durante un período de 2 años con tiempo de seguimiento hasta de 18 meses, 67% menores de 6 años y de ellos 2 pacientes menores de 1 año. Hubo predominio de pacientes de sexo masculino. El síntoma "jiba" fue el mas frecuente. La localización mas frecuente de la lesión fue el nivel dorsal. Todos recibieron tratamiento médico con 4 drogas, 14 de ellos necesitaron de métodos ortopédicos y solo 6 fueron sometidos a corrección quirúrgica. En mas del 50% hubo una evolución favorable hacia la curación o la mejoría con secuelas.
    Keywords Neurosciences. Biological psychiatry. Neuropsychiatry ; RC321-571 ; Internal medicine ; RC31-1245 ; Medicine ; R
    Language English
    Publishing date 1989-09-01T00:00:00Z
    Publisher Academia Brasileira de Neurologia - ABNEURO
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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