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  1. Article ; Online: Value of different CTO scoring systems in predicting procedural success in coronary chronic total occlusion intervention in Egyptian patients.

    AlAshry, Ahmed Mohammed Ali / Nagiub, Muhammed Nagy / Ismael, Magdy Farouk Ahmed / Alghonaimy, Wesam

    The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology

    2024  Volume 76, Issue 1, Page(s) 30

    Abstract: Background: Chronic total occlusion (CTO) lesions in coronary arteries pose a significant challenge for coronary interventionists, often leading to referrals for coronary artery bypass graft surgery (CABG). Successful percutaneous coronary intervention ( ...

    Abstract Background: Chronic total occlusion (CTO) lesions in coronary arteries pose a significant challenge for coronary interventionists, often leading to referrals for coronary artery bypass graft surgery (CABG). Successful percutaneous coronary intervention (PCI) for CTOs requires accurate assessment of procedural potential. This study, comprising 100 Egyptian patients aged 37-81, compares the predictive efficacy of various CTO scoring systems in PCI success determination. Patients with CTO in at least one coronary artery, planned for elective PCI based on objective evidence of ischemia, were included. Experienced operators performed PCI, recording procedural variables, and assessing complications. Logistic regression analysis revealed an inverse linear relationship between success rates and score values across all systems.
    Results: Although, the predictive capacity of the scores was similar, with slight differences. The Euro CTO (CASTLE) score
    Conclusion: The CASTLE score
    Language English
    Publishing date 2024-03-05
    Publishing country Germany
    Document type Journal Article
    ISSN 2090-911X
    ISSN (online) 2090-911X
    DOI 10.1186/s43044-024-00458-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Detection of positively remodeled coronary artery lesions by multislice CT and its impact on cardiovascular future events.

    Galal, Haitham / Rashid, Tarek / Alghonaimy, Wesam / Kamal, Diaa

    The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology

    2019  Volume 71, Issue 1, Page(s) 26

    Abstract: Background: Positive arterial remodeling may be a characteristic of early proliferative lesions. The study was done to identify the different morphological characteristics of the positively remodeled coronary lesions, and causing non-significant ... ...

    Abstract Background: Positive arterial remodeling may be a characteristic of early proliferative lesions. The study was done to identify the different morphological characteristics of the positively remodeled coronary lesions, and causing non-significant arterial stenosis, as detected by multislice computed tomography coronary angiography (MSCT CA) and its predictors of cardiovascular clinical events at 90-day follow-up. The study included 55 patients who were candidate for MSCT CA and found to have a single-vessel disease with less than 70% stenosis positively remodeled lesions. The most expansive or solitary lesion was selected for each patient. Positive remodeling defined as remodeling index (RI) > 1.05. We followed the patients clinically for 90 days.
    Results: Twenty-four patients had a history of acute coronary syndrome at initial presentation with normal LV systolic function for all studied patients. Dyslipidemia was found in 37 patients (67.3%) while diabetes was found in 29 patients (52.7%). The majority of the lesions were found in the proximal LAD (43.6%). The mean calculated remodeling index was 1.41 ± 0.25. At the end of 90 days, 25 patients had clinical events in the form of unstable coronary syndromes, coronary interventions, or coronary angiography related to the index lesion. The predictors of clinical events were duration of DM, higher degree of luminal narrowing, calculated wall/lumen area percentage, plaque burden, plaque-specific calcification, and total calcium score at remodeling site as well as a lower percentage of low-attenuation plaque area. The mean calculated wall/lumen area percentage was 263.72 ± 122.71%. A cut-off value of > 226% was found a predictor for clinical events. The mean plaque burden percentage was 69.72 ± 9.71%, a value of > 69% was found a predictor for clinical events. Both values had a sensitivity of 68% and specificity of 86.6% and PPV of 81%. Positively remodeled lesions with a high RI > 1.4 were correlated with patients who had acute coronary syndrome on their initial presentation.
    Conclusion: Different morphological characteristics of positively remodeled non-occlusive atherosclerotic plaques as detected by multislice CT coronary angiography may be good potential predictors of future cardiovascular events.
    Language English
    Publishing date 2019-11-21
    Publishing country Germany
    Document type Journal Article
    ISSN 2090-911X
    ISSN (online) 2090-911X
    DOI 10.1186/s43044-019-0029-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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