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Article ; Online: The impact of a prolonged lockdown and use of telemedicine on glycemic control in people with type 1 diabetes during the COVID-19 outbreak in Saudi Arabia.

Alharthi, Sahar K / Alyusuf, Ebtihal Y / Alguwaihes, Abdullah M / Alfadda, Assim / Al-Sofiani, Mohammed E

Diabetes research and clinical practice

2021  Volume 173, Page(s) 108682

Abstract: Background: To minimize the spread of Coronavirus Disease-2019, Saudi Arabia imposed a nationwide lockdown for over 6 weeks. We examined the impact of lockdown on glycemic control in individuals with type 1 diabetes (T1D) using continuous glucose ... ...

Abstract Background: To minimize the spread of Coronavirus Disease-2019, Saudi Arabia imposed a nationwide lockdown for over 6 weeks. We examined the impact of lockdown on glycemic control in individuals with type 1 diabetes (T1D) using continuous glucose monitoring (CGM); and assessed whether changes in glycemic control differ between those who attended a telemedicine visit during lockdown versus those who did not.
Materials and methods: Flash CGM data from 101 individuals with T1D were retrospectively evaluated. Participants were categorized into two groups: Attended a telemedicine visit during lockdown (n = 61) or did not attend (n = 40). Changes in CGM metrics from the last 2 weeks pre-lockdown period (Feb 25 - March 9, 2020) to the last 2 weeks of complete lockdown period (April 7-20, 2020) were examined in the two groups.
Results: Those who attended a telemedicine visit during the lockdown period had a significant improvement in the following CGM metrics by the end of lockdown: Average glucose (from 180 to 159 mg/dl, p < 0.01), glycemic management indicator (from 7.7 to 7.2%, p = 0.03), time in range (from 46 to 55%, p < 0.01), and time above range (from 48 to 35%, p < 0.01) without significant changes in time below range, number of daily scans or hypoglycemic events, and other indices. In contrast, there were no significant changes in any of the CGM metrics during lockdown in those who did not attend telemedicine.
Conclusions: A six-week lockdown did not worsen, nor improve, glycemic control in individuals with T1D who did not attend a telemedicine visit. Whereas those who attended a telemedicine visit had a significant improvement in glycemic metrics; supporting the clinical effectiveness of telemedicine in diabetes care.
MeSH term(s) Adolescent ; Adult ; Blood Glucose/metabolism ; Blood Glucose Self-Monitoring/methods ; COVID-19/epidemiology ; Communicable Disease Control/methods ; Communicable Disease Control/statistics & numerical data ; Diabetes Mellitus, Type 1/blood ; Diabetes Mellitus, Type 1/drug therapy ; Diabetes Mellitus, Type 1/epidemiology ; Disease Outbreaks ; Female ; Glycemic Control/methods ; Glycemic Control/standards ; Humans ; Hypoglycemic Agents/therapeutic use ; Male ; Program Evaluation ; Quarantine/methods ; Quarantine/statistics & numerical data ; Retrospective Studies ; SARS-CoV-2 ; Saudi Arabia/epidemiology ; Telemedicine/organization & administration ; Telemedicine/statistics & numerical data ; Young Adult
Chemical Substances Blood Glucose ; Hypoglycemic Agents
Language English
Publishing date 2021-02-02
Publishing country Ireland
Document type Journal Article
ZDB-ID 632523-3
ISSN 1872-8227 ; 0168-8227
ISSN (online) 1872-8227
ISSN 0168-8227
DOI 10.1016/j.diabres.2021.108682
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