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  1. Article: Radiographic case report of a heart transplanted patient suffering from COVID-19.

    Alizadeh, Leona S / Albrecht, Moritz H / Booz, Christian

    Heliyon

    2021  Volume 7, Issue 4, Page(s) e06688

    Abstract: In context of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), patients with certain comorbidities and high age, as well as male sex are considered to represent the risk group for severe course of disease. Corona-virus disease 2019 (COVID-19) ...

    Abstract In context of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), patients with certain comorbidities and high age, as well as male sex are considered to represent the risk group for severe course of disease. Corona-virus disease 2019 (COVID-19) typical CT-patterns include bilateral, peripheral ground glass opacity (GGO), septal thickening, bronchiectasis, consolidation as well as associated pleural effusion. We report a 77-year-old heart transplanted patient with confirmed COVID-19 infection and coronary heart disease, diabetes type II and other risk factors. Notably, only slight clinical symptoms were reported and repeated computed tomography (CT) scans showed an atypical course of CT findings during his hospitalization.
    Language English
    Publishing date 2021-04-03
    Publishing country England
    Document type Case Reports
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2021.e06688
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Magnetic Resonance Angiography for Prostatic Artery Embolization: Origin of a Prostatic Artery from the Accessory Obturator Artery.

    Chen, Kueian / Booz, Christian / Fouad, Mohamed E M / Alizadeh, Leona S / Mackrodt, Sophie / Vogl, Thomas J

    Journal of vascular and interventional radiology : JVIR

    2023  Volume 34, Issue 5, Page(s) 933–935

    MeSH term(s) Male ; Humans ; Prostate/diagnostic imaging ; Prostate/blood supply ; Magnetic Resonance Angiography ; Embolization, Therapeutic ; Prostatic Hyperplasia/diagnostic imaging ; Prostatic Hyperplasia/therapy ; Prostatic Hyperplasia/pathology ; Arteries/diagnostic imaging ; Arteries/pathology ; Treatment Outcome
    Language English
    Publishing date 2023-01-24
    Publishing country United States
    Document type Letter
    ZDB-ID 1137756-2
    ISSN 1535-7732 ; 1051-0443
    ISSN (online) 1535-7732
    ISSN 1051-0443
    DOI 10.1016/j.jvir.2023.01.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Advancing Differentiation of Hepatic Metastases in Malignant Melanoma through Dual-Energy Computed Tomography Rho/Z Maps.

    Yel, Ibrahim / Koch, Vitali / Gruenewald, Leon D / Mahmoudi, Scherwin / Alizadeh, Leona S / Goekduman, Aynur / Eichler, Katrin / Vogl, Thomas J / Dimitrova, Mirela / Booz, Christian

    Diagnostics (Basel, Switzerland)

    2024  Volume 14, Issue 7

    Abstract: Objectives: The aim of this study is to evaluate the diagnostic accuracy of dual-energy computed tomography (DECT)-based Rho/Z maps in differentiating between metastases and benign liver lesions in patients diagnosed with malignant melanoma compared to ... ...

    Abstract Objectives: The aim of this study is to evaluate the diagnostic accuracy of dual-energy computed tomography (DECT)-based Rho/Z maps in differentiating between metastases and benign liver lesions in patients diagnosed with malignant melanoma compared to conventional CT value measurements.
    Methods: This retrospective study included 73 patients (mean age, 70 ± 13 years; 43 m/30 w) suffering from malignant melanoma who had undergone third-generation DECT as part of tumor staging between December 2017 and December 2021. For this study, we measured Rho (electron density) and Z (effective atomic number) values as well as Hounsfield units (HUs) in hypodense liver lesions. Values were compared, and diagnostic accuracy for differentiation was computed using receiver operating characteristic (ROC) curve analyses. Additional performed MRI or biopsies served as a standard of reference.
    Results: A total of 136 lesions (51 metastases, 71 cysts, and 14 hemangiomas) in contrast-enhanced DECT images were evaluated. The most notable discrepancy (
    Conclusions: Rho and Z measurements derived from DECT allow for improved differentiation of liver metastases and benign liver cysts in patients with malignant melanoma compared to conventional CT value measurements. In contrast, in differentiation between liver hemangiomas and metastases, Rho/Z maps show inferior diagnostic accuracy. Therefore, differentiation between these two lesions remains a challenge for CT imaging.
    Language English
    Publishing date 2024-03-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics14070742
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: A case of myocarditis after COVID-19 vaccination: incidental or consequential?

    Alizadeh, Leona S / Koch, Vitali / Yel, Ibrahim / Grünewald, Leon D / Mathies, Daniel / Martin, Simon / Vogl, Thomas J / Rauschning, Dominic / Booz, Christian

    Heliyon

    2022  Volume 8, Issue 6, Page(s) e09537

    Abstract: Vaccination represents one of the fundamentals in the fight against SARS-CoV-2. Myocarditis has been reported as a rare but possible adverse consequence of different vaccines, and its clinical presentation can range from mild symptoms to acute heart ... ...

    Abstract Vaccination represents one of the fundamentals in the fight against SARS-CoV-2. Myocarditis has been reported as a rare but possible adverse consequence of different vaccines, and its clinical presentation can range from mild symptoms to acute heart failure. We report a case of a 29-year-old man who presented with fever and retrosternal pain after receiving SARS-CoV-2 vaccine. Cardiac magnetic resonance imaging and laboratory data revealed typical findings of acute myocarditis.
    Language English
    Publishing date 2022-05-28
    Publishing country England
    Document type Case Reports
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2022.e09537
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Case report of rare congenital cardiovascular anomalies associated with truncus arteriosus type 2.

    Alizadeh, Leona S / Koch, Vitali / Grünewald, Leon D / Yel, Ibrahim / Mathies, Daniel / Rauschning, Dominic / Vogl, Thomas J / Booz, Christian

    Heliyon

    2022  Volume 8, Issue 10, Page(s) e11033

    Abstract: Truncus arteriosus (TA) is a very rare congenital anomaly with complex cardiovascular anatomy and high lethality also due to severe associated anatomical variants and pathologies. As TA has a massive impact on the survival of a newborn and usually has to ...

    Abstract Truncus arteriosus (TA) is a very rare congenital anomaly with complex cardiovascular anatomy and high lethality also due to severe associated anatomical variants and pathologies. As TA has a massive impact on the survival of a newborn and usually has to be surgically treated. Thus, it is of high importance to understand this congenital cardiovascular disease and associated complications, to improve life expectancy and outcome of these patients. We recently came across a newborn female patient with a rare complex case of persistent TA type 2 associated with further complex cardiovascular anomalies, who received a contrast enhanced CT scan on the 3 rd day post-partum, showing complex cardiovascular abnormalities that were ultimately incompatible with life.
    Language English
    Publishing date 2022-10-12
    Publishing country England
    Document type Case Reports
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2022.e11033
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: A case of Myocarditis after COVID-19 vaccination: Incidental or Consequential?

    Alizadeh, Leona S. / Koch, Vitali / Yel, Ibrahim / Grünewald, Leon D. / Mathies, Daniel / Martin, Simon / Vogl, Thomas J. / Rauschning, Dominic / Booz, Christian

    Heliyon. 2022 May 19,

    2022  

    Abstract: Vaccination represents one of the fundamentals in the fight against SARS-CoV-2. Myocarditis has been reported as a rare but possible adverse consequence of different vaccines, and its clinical presentation can range from mild symptoms to acute heart ... ...

    Abstract Vaccination represents one of the fundamentals in the fight against SARS-CoV-2. Myocarditis has been reported as a rare but possible adverse consequence of different vaccines, and its clinical presentation can range from mild symptoms to acute heart failure. We report a case of a 29-year-old man who presented with fever and retrosternal pain after receiving SARS-CoV-2 vaccine. Cardiac magnetic resonance imaging and laboratory data revealed typical findings of acute myocarditis.
    Keywords COVID-19 infection ; Severe acute respiratory syndrome coronavirus 2 ; fever ; heart failure ; magnetism ; myocarditis ; pain ; vaccination ; vaccines
    Language English
    Dates of publication 2022-0519
    Publishing place Elsevier Ltd
    Document type Article
    Note Pre-press version
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2022.e09537
    Database NAL-Catalogue (AGRICOLA)

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  7. Article ; Online: Case report of rare congenital cardiovascular anomalies associated with truncus arteriosus type 2

    Alizadeh, Leona S. / Koch, Vitali / Grünewald, Leon D. / Yel, Ibrahim / Mathies, Daniel / Rauschning, Dominic / Vogl, Thomas J. / Booz, Christian

    Heliyon. 2022 Oct., v. 8, no. 10 p.e11033-

    2022  

    Abstract: Truncus arteriosus (TA) is a very rare congenital anomaly with complex cardiovascular anatomy and high lethality also due to severe associated anatomical variants and pathologies. As TA has a massive impact on the survival of a newborn and usually has to ...

    Abstract Truncus arteriosus (TA) is a very rare congenital anomaly with complex cardiovascular anatomy and high lethality also due to severe associated anatomical variants and pathologies. As TA has a massive impact on the survival of a newborn and usually has to be surgically treated. Thus, it is of high importance to understand this congenital cardiovascular disease and associated complications, to improve life expectancy and outcome of these patients. We recently came across a newborn female patient with a rare complex case of persistent TA type 2 associated with further complex cardiovascular anomalies, who received a contrast enhanced CT scan on the 3 rd day post-partum, showing complex cardiovascular abnormalities that were ultimately incompatible with life.
    Keywords cardiovascular diseases ; case studies ; computed tomography ; congenital abnormalities ; death ; females ; longevity ; neonates ; patients ; Truncus arteriosus ; Fetal heart ; Heart defects ; Congenital
    Language English
    Dates of publication 2022-10
    Publishing place Elsevier Ltd
    Document type Article ; Online
    Note Use and reproduction
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2022.e11033
    Database NAL-Catalogue (AGRICOLA)

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  8. Article: Diagnosis of Uric Acid-Based Urine Sedimentation in the Bladder Using Dual-Energy CT.

    Booz, Christian / Yel, Ibrahim / Wichmann, Julian L / Martin, Simon S / Koch, Vitali / Gruenewald, Leon D / Alizadeh, Leona S / Vogl, Thomas J / D'Angelo, Tommaso

    Diagnostics (Basel, Switzerland)

    2023  Volume 13, Issue 3

    Abstract: Urine sedimentation in the bladder can occur in various circumstances and can lead to urinary obstruction/stasis with associated pain. It is usually diagnosed with an ultrasound; however, CT is also used to assess the amount and to further check for ... ...

    Abstract Urine sedimentation in the bladder can occur in various circumstances and can lead to urinary obstruction/stasis with associated pain. It is usually diagnosed with an ultrasound; however, CT is also used to assess the amount and to further check for urinary stones. Depending on the composition, urine sedimentation and stones can be treated medically by alkalinisation of the urine with potassium sodium hydrogen citrate in the case of uric acid-based sedimentation/stones. Due to technical developments and improved material differentiation and characterisation in CT imaging, dual-energy CT allows for differentiation of uric acid from calcium, which can be used for sedimentation/stone composition analysis. Subsequently, treatment decisions can be made based on the findings in dual-energy CT.
    Language English
    Publishing date 2023-02-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics13030542
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Diagnosis of an Acute Anterior Wall Infarction in Dual-Energy CT.

    Gökduman, Aynur / Yel, Ibrahim / Vogl, Thomas J / Dimitrova, Mirela / Grünewald, Leon D / Koch, Vitali / Alizadeh, Leona S / Brendlin, Andreas S / Othman, Ahmed E / Martin, Simon S / D'Angelo, Tommaso / Blandino, Alfredo / Mazziotti, Silvio / Booz, Christian

    Diagnostics (Basel, Switzerland)

    2023  Volume 13, Issue 4

    Abstract: Due to its high morbidity and mortality, myocardial infarction is the leading cause of death worldwide. Against this background, rapid diagnosis is of immense importance. Especially in case of an atypical course, the correct diagnosis may be delayed and ... ...

    Abstract Due to its high morbidity and mortality, myocardial infarction is the leading cause of death worldwide. Against this background, rapid diagnosis is of immense importance. Especially in case of an atypical course, the correct diagnosis may be delayed and thus lead to increased mortality rates. In this report, we present a complex case of acute coronary syndrome. A triple-rule-out CT examination was performed in dual-energy CT (DECT) mode. While pulmonary artery embolism and aortic dissection could be ruled out with conventional CT series, the presence of anterior wall infarction was only detectable on DECT reconstructions. Subsequently, adequate and rapid therapy was then initiated leading to survival of the patient.
    Language English
    Publishing date 2023-02-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics13040761
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Dual-Energy CT in Cardiothoracic Imaging: Current Developments.

    Alizadeh, Leona S / Vogl, Thomas J / Waldeck, Stephan S / Overhoff, Daniel / D'Angelo, Tommaso / Martin, Simon S / Yel, Ibrahim / Gruenewald, Leon D / Koch, Vitali / Fulisch, Florian / Booz, Christian

    Diagnostics (Basel, Switzerland)

    2023  Volume 13, Issue 12

    Abstract: This article describes the technical principles and clinical applications of dual-energy computed tomography (DECT) in the context of cardiothoracic imaging with a focus on current developments and techniques. Since the introduction of DECT, different ... ...

    Abstract This article describes the technical principles and clinical applications of dual-energy computed tomography (DECT) in the context of cardiothoracic imaging with a focus on current developments and techniques. Since the introduction of DECT, different vendors developed distinct hard and software approaches for generating multi-energy datasets and multiple DECT applications that were developed and clinically investigated for different fields of interest. Benefits for various clinical settings, such as oncology, trauma and emergency radiology, as well as musculoskeletal and cardiovascular imaging, were recently reported in the literature. State-of-the-art applications, such as virtual monoenergetic imaging (VMI), material decomposition, perfused blood volume imaging, virtual non-contrast imaging (VNC), plaque removal, and virtual non-calcium (VNCa) imaging, can significantly improve cardiothoracic CT image workflows and have a high potential for improvement of diagnostic accuracy and patient safety.
    Language English
    Publishing date 2023-06-19
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics13122116
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