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  1. Article ; Online: What's needed to rebuild Saudi Arabia's research reputation.

    Alkahtani, Theeb Ayedh

    Nature

    2024  Volume 626, Issue 7997, Page(s) 33

    MeSH term(s) Saudi Arabia ; Research/standards ; Research/trends
    Language English
    Publishing date 2024-01-31
    Publishing country England
    Document type Letter
    ZDB-ID 120714-3
    ISSN 1476-4687 ; 0028-0836
    ISSN (online) 1476-4687
    ISSN 0028-0836
    DOI 10.1038/d41586-024-00198-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 26: Show issues Location:
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  2. Article: The current reproduction number of COVID-19 in Saudi Arabia: is the disease controlled?

    Alkahtani, Theeb Ayedh / Alakeel, Abdullah / Alakeel, Reem Abdullah / Khorshid, Faten Abdulrahman / Alshammari, Hisham Hamoud / Alguwaihes, Abdullah M. / Almohideb, Mohammad / Ali, Eman Merghani / Bin-Jumah, May / Abdel-Daim, Mohamed M. / Jammah, Anwar Ali

    Environmental science and pollution research. 2021 Sept., v. 28, no. 33

    2021  

    Abstract: The infectiousness of COVID-19 is high among the susceptible population, making the calculation of the reproduction number (R) an essential step to implement preventive measures. We aim to estimate COVID-19 transmission to determine if the disease is ... ...

    Abstract The infectiousness of COVID-19 is high among the susceptible population, making the calculation of the reproduction number (R) an essential step to implement preventive measures. We aim to estimate COVID-19 transmission to determine if the disease is successfully controlled or extra measured should be adopted to attain this goal. The daily incidence data of COVID-19 in Saudi Arabia from March 2ⁿᵈ, 2020, to April 4ᵗʰ, 2021, were obtained from the continuously updated Saudi Ministry of Health COVID-19 repository. To get accurate estimation of the situation over the last 4 months (from December 1ˢᵗ, 2020, to April 4ᵗʰ, 2021), we calculated the weekly (every 7 days) R starting from March 2ⁿᵈ, 2020, and till the last week of the available data. The calculated values of R were represented as median, first quantile (Q1), and third quantile (Q3). As early as the first week of December 2020, the median R was 0.81 (0.80–0.83) which means that each existing infected case would transmit infection to only one person. This was followed by fluctuations over the next few weeks around R value of 1, reaching its highest level of 1.45 (1.42–1.47) between December 31ˢᵗ, 2020, and January 6ᵗʰ, 2021. This was followed by a relatively steady decline over the following weeks, with some till mid-March where the R values started to slightly rise again. Social distancing, protective precautions, avoiding abuse of the partial lifting, expanding the screening process, and other Saudi measures sound to be successful and should be replicated in similar communities. This measure should be continued till the vaccination process is completed, to reduce the number of contacts and to avoid uncontrolled transmission of the disease.
    Keywords COVID-19 infection ; at-risk population ; pollution ; reproduction ; research ; vaccination ; Saudi Arabia
    Language English
    Dates of publication 2021-09
    Size p. 44812-44817.
    Publishing place Springer Berlin Heidelberg
    Document type Article
    Note Review
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-021-14217-6
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    In stock of ZB MED Bonn / Germany

    Z 5915: Show issues

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  3. Article ; Online: The current reproduction number of COVID-19 in Saudi Arabia: is the disease controlled?

    Alkahtani, Theeb Ayedh / Alakeel, Abdullah / Alakeel, Reem Abdullah / Khorshid, Faten Abdulrahman / Alshammari, Hisham Hamoud / Alguwaihes, Abdullah M / Almohideb, Mohammad / Ali, Eman Merghani / Bin-Jumah, May / Abdel-Daim, Mohamed M / Jammah, Anwar Ali

    Environmental science and pollution research international

    2021  Volume 28, Issue 33, Page(s) 44812–44817

    Abstract: The infectiousness of COVID-19 is high among the susceptible population, making the calculation of the reproduction number (R) an essential step to implement preventive measures. We aim to estimate COVID-19 transmission to determine if the disease is ... ...

    Abstract The infectiousness of COVID-19 is high among the susceptible population, making the calculation of the reproduction number (R) an essential step to implement preventive measures. We aim to estimate COVID-19 transmission to determine if the disease is successfully controlled or extra measured should be adopted to attain this goal. The daily incidence data of COVID-19 in Saudi Arabia from March 2
    MeSH term(s) COVID-19 ; Humans ; Reproduction ; SARS-CoV-2 ; Saudi Arabia
    Language English
    Publishing date 2021-07-09
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-021-14217-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

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  4. Article ; Online: Efficacy and safety of doravirine in treatment-naive HIV-1-infected adults: a systematic review and meta-analysis.

    Afify, Marwa Adel / Ahmed, Iman Gamal Ghareeb / Alkahtani, Theeb Ayedh / Altulayhi, Raed Ibrahim / Alrowili, Amjad Saud Mhrb / Ghozy, Sherief / Bin-Jumah, May / Abdel-Daim, Mohamed M

    Environmental science and pollution research international

    2020  Volume 28, Issue 9, Page(s) 10576–10588

    Abstract: This research aims to study the safety and efficacy of doravirine in the treatment of HIV-1 (human immunodeficiency virus) patients. We conducted an electronic search in eight databases for the inclusion of eligible studies. We have only included ... ...

    Abstract This research aims to study the safety and efficacy of doravirine in the treatment of HIV-1 (human immunodeficiency virus) patients. We conducted an electronic search in eight databases for the inclusion of eligible studies. We have only included randomized controlled trials (RCTs) that study the safety and efficacy of doravirine in the treatment of HIV-1 adult patients. Six papers were included in this meta-analysis. For network (direct and indirect) estimates, the doravirine 100 mg treatment strategy found to have the highest efficacy (P score = 0.786) followed by doravirine 25 mg (P score = 0.684), efavirenz 600 mg (P score = 0.574), doravirine 200 mg (P score = 0.532), 100 mg ritonavir and plus 800 mg darunavir (P score = 0.416), and placebo (P score = 0.009), respectively. Regarding drug-related AE, the placebo group found to have the highest safety profile with the least AE rates (P score = 0.927) followed by doravirine 100 mg (P score = 0.720), 100 mg ritonavir and plus 800 mg darunavir (P score = 0.717), doravirine 25 mg (P score = 0.336), doravirine 200 mg (P score = 0.258), and efavirenz 600 mg (P score = 0.043), respectively. Nevertheless, there was no significant difference between DOR 100 mg in comparison with 100 mg ritonavir and plus 800 mg darunavir (OR = 1.14; 95% CI = 0.23-5.74), DOR 25 mg (OR = 0.37; 95% CI = 0.06-2.34), DOR 200 mg (OR = 0.89; 95% CI = 0.17-4.59), or efavirenz 600 mg (OR = 0.58; 95% CI = 0.17-1.98). Moreover, the pairwise (direct only) comparisons did not show a significant difference between doravirine (all doses) and other treatment groups. Doravirine could be counted as an efficacious, safe, and well-tolerated treatment option that is preferable to other regimens for the initial therapy of individuals with HIV-1 infection.
    MeSH term(s) Adult ; Anti-HIV Agents/therapeutic use ; HIV Infections/drug therapy ; HIV-1 ; Humans ; Pyridones ; Triazoles
    Chemical Substances Anti-HIV Agents ; Pyridones ; Triazoles ; doravirine (913P6LK81M)
    Language English
    Publishing date 2020-10-24
    Publishing country Germany
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-020-11267-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

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  5. Article ; Online: The Current Situation of COVID-19 in Saudi Arabia

    Alkahtani, Theeb Ayedh / Alakeel, Abdullah / Alakeel, Reem Abdullah / Khorshid, Faten Abdulrahman / Alshammari, Hisham Hamoud / Alguwaihes, Abdullah M / Almohideb, Mohammad / Ali, Eman Merghani / Shujaa, Asaad / Jammah, Anwar Ali

    SSRN Electronic Journal ; ISSN 1556-5068

    Overview and Future Forecasting for Cases and Deaths

    2020  

    Keywords covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    DOI 10.2139/ssrn.3591474
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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