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  1. Article ; Online: Robotic general surgery experience: a gradual progress from simple to more complex procedures.

    Al-Naami, M / Anjum, M N / Aldohayan, A / Al-Khayal, K / Alkharji, H

    The international journal of medical robotics + computer assisted surgery : MRCAS

    2013  Volume 9, Issue 4, Page(s) 486–491

    Abstract: Background: Robotic surgery was introduced at our institution in 2003, and we used a progressive approach advancing from simple to more complex procedures.: Methods: A retrospective chart review.: Results: Cases included totalled 129. Set-up and ... ...

    Abstract Background: Robotic surgery was introduced at our institution in 2003, and we used a progressive approach advancing from simple to more complex procedures.
    Methods: A retrospective chart review.
    Results: Cases included totalled 129. Set-up and operative times have improved over time and with experience. Conversion rates to standard laparoscopic or open techniques were 4.7% and 1.6%, respectively. Intraoperative complications (6.2%), blood loss and hospital stay were directly proportional to complexity. There were no mortalities and the postoperative complication rate (13.2%) was within accepted norms.
    Conclusion: Our findings suggest that robot technology is presently most useful in cases tailored toward its advantages, i.e. those confined to a single space, those that require performance of complex tasks, and re-do procedures.
    MeSH term(s) Adult ; Female ; General Surgery/statistics & numerical data ; Hospital Mortality ; Humans ; Incidence ; Length of Stay/statistics & numerical data ; Male ; Operative Time ; Postoperative Complications/mortality ; Risk Factors ; Robotics/utilization ; Saudi Arabia/epidemiology ; Surgery, Computer-Assisted/mortality ; Surgery, Computer-Assisted/utilization
    Language English
    Publishing date 2013-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 2151860-9
    ISSN 1478-596X ; 1478-5951
    ISSN (online) 1478-596X
    ISSN 1478-5951
    DOI 10.1002/rcs.1521
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Clinicopathological Features and Predictive Factors for Colorectal Cancer Outcome in the Kingdom of Saudi Arabia.

    Aldiab, Abdurrahman / Al Khayal, Khayal A / Al Obaid, Omar A / Alsheikh, Ahmed / Alsaleh, Khalid / Shahid, Mohamed / Alkharji, Hana

    Oncology

    2017  Volume 92, Issue 2, Page(s) 75–86

    Abstract: Background/aims: Colorectal cancer (CRC) is the most frequent cancer and a leading cause of cancer death in the Kingdom of Saudi Arabia (KSA). To date, no nationwide screening programs have been adopted. This prospective, longitudinal study investigated ...

    Abstract Background/aims: Colorectal cancer (CRC) is the most frequent cancer and a leading cause of cancer death in the Kingdom of Saudi Arabia (KSA). To date, no nationwide screening programs have been adopted. This prospective, longitudinal study investigated factors influencing the outcome of CRC in Saudi patients.
    Methods: Patients completed a CRC awareness questionnaire. Colonoscopy, CT/MRI, histopathology of tumor biopsies, and KRAS and BRAF testing were performed. Patients were treated according to their stage. All patients were followed until the end of the study and 3- and 5-year survival was assessed.
    Results: Sixty percent of study patients with sporadic CRC presented with significantly advanced disease (stages III and IV) with or without metastases at entry. Patients showed low levels of awareness of the risk factors and signs of CRC. Patients presented at a median age of 50 years. Family history of CRC and ulcerative colitis were positive in 11 and 6% of patients, respectively. Stage III/IV tumors with distant metastases at enrollment, right-sided tumors, mucinous tumors, lymphovascular invasion, and KRAS (51%) or BRAF (28%) mutations predicted poor prognosis and survival.
    Conclusion: CRC in KSA is usually diagnosed at advanced stages with metastases and KRAS/BRAF, and is associated with poor prognosis and short survival. Nationwide awareness campaigns and screening programs for CRC are critical for prevention, early detection and adequate management of CRC.
    MeSH term(s) Adult ; Colorectal Neoplasms/genetics ; Colorectal Neoplasms/pathology ; Colorectal Neoplasms/therapy ; Female ; Genes, ras ; Humans ; Male ; Middle Aged ; Prognosis ; Proto-Oncogene Proteins B-raf/genetics ; Saudi Arabia ; Survival Rate ; Treatment Outcome
    Chemical Substances BRAF protein, human (EC 2.7.11.1) ; Proto-Oncogene Proteins B-raf (EC 2.7.11.1)
    Language English
    Publishing date 2017
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 250101-6
    ISSN 1423-0232 ; 0030-2414
    ISSN (online) 1423-0232
    ISSN 0030-2414
    DOI 10.1159/000450857
    Database MEDical Literature Analysis and Retrieval System OnLINE

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