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  1. Article: Severe acute hepatitis of unknown etiology in children in 2022: A Narrative Review.

    Namakin, Kosar / Naserghandi, Alvand / Allameh, Seyed Farshad

    New microbes and new infections

    2023  Volume 51, Page(s) 101087

    Abstract: Severe cases of acute hepatitis have been reported all around the world since 5 April 2022. Common viral hepatitis agents (HAV, HBV, HCV, HDV, and HEV) were ruled out by laboratory investigations, impelling the term "acute non-A-E hepatitis". Common ... ...

    Abstract Severe cases of acute hepatitis have been reported all around the world since 5 April 2022. Common viral hepatitis agents (HAV, HBV, HCV, HDV, and HEV) were ruled out by laboratory investigations, impelling the term "acute non-A-E hepatitis". Common manifestations consist of abdominal pain, jaundice, and vomiting. A highly elevated level of liver enzymes was a remarkable laboratory finding among the patients. Currently, there is no clear etiology and thus treatment for the condition. Adenovirus serotype 41 (ad-41) was detected in most of the patients even though there is no elucidated link between Adenovirus and acute hepatitis. Other viral agents such as SARS-CoV-2 tested positive in a few cases. Treatment strategies depend on the severity, complications, and sequela of acute hepatitis and can vary widely from supportive therapy to liver transplantation. As of 8 July 2022, 1010 probable cases were reported from 35 countries. More than half were from the European region and were mostly children under the age of 6 years. Among different hypotheses about the etiology of severe acute non-A-E hepatitis, adenovirus-41 is of great importance but further assessments are needed to prove any definite link between ad-41 and severe acute hepatitis.
    Language English
    Publishing date 2023-01-21
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2750179-6
    ISSN 2052-2975
    ISSN 2052-2975
    DOI 10.1016/j.nmni.2023.101087
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Corona virus and one step backward.

    Basirat, Vahid / Allameh, Seyed Farshad

    Iranian journal of microbiology

    2020  Volume 12, Issue 4, Page(s) 368–369

    Keywords covid19
    Language English
    Publishing date 2020-09-05
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2652849-6
    ISSN 2008-4447 ; 2008-3289
    ISSN (online) 2008-4447
    ISSN 2008-3289
    DOI 10.18502/ijm.v12i4.3942s
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Case series of papillectomy by endoscopic retrograde cholangiopancreatography (ERCP).

    Roushan, Nader / Allameh, Seyed Farshad / Eslami, Omid

    Medical journal of the Islamic Republic of Iran

    2018  Volume 32, Page(s) 43

    Abstract: Ampullary neoplasms are one of the causes of obstructive jaundice. Endoscopic retrograde cholangiopancreatography (ERCP) is useful procedure for diagnosing and tissue sampling of ampullary neoplasms. Ampullectomy by resecting entire ampulla provides ... ...

    Abstract Ampullary neoplasms are one of the causes of obstructive jaundice. Endoscopic retrograde cholangiopancreatography (ERCP) is useful procedure for diagnosing and tissue sampling of ampullary neoplasms. Ampullectomy by resecting entire ampulla provides whole lesion for pathologic evaluation and also is appropriate for real pathologic staging for further management decision but ampullectomy considered as a heroic endoscopic procedure. We share our experience in this field and explain our results.
    Language English
    Publishing date 2018-05-30
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 1095990-7
    ISSN 1016-1430
    ISSN 1016-1430
    DOI 10.14196/mjiri.32.43
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Disruption in Medical Care of Non-COVID Patients in COVID-19 Pandemic

    Allameh, Seyed Farshad / Shateri Amiri, Bahareh / Zarei Jalalabadi, Narjes

    Advanced Journal of Emergency Medicine; Vol 4 No 2s (2020): COVID-19 ; 2588-400X

    2020  

    Abstract: In December 2019, a novel coronavirus (2019-nCoV) was detected in Wuhan Hubei province, China. The virus has caused a global concern because of its high potential for transmission, high morbidity and mortality. COVID-19 spreads so rapidly across an ... ...

    Abstract In December 2019, a novel coronavirus (2019-nCoV) was detected in Wuhan Hubei province, China. The virus has caused a global concern because of its high potential for transmission, high morbidity and mortality. COVID-19 spreads so rapidly across an increasing number of countries worldwide that it has been found in more than 200 countries so far. The World Health Organization (WHO) has declared COVID-19 a pandemic and public health threat. In general, COVID-19 is an infectious disease caused bysevere acute respiratory syndrome coronavirus 2(SARS-CoV-2). A case fatality rate of approximately 2.3% has been reported for COVID-19. New fever, cough, lymphopenia and bilateral lung infiltrations are characteristic but not diagnostic for COVID-19. Sore throat, dyspnea, myalgia, diarrhea, and abdominal pain are other presentations of COVID-19. We should also be attentive to the probability of atypical presentations in patients who are immunocompromised. While the majority of cases result in mild respiratory tract symptoms like acute bronchitis, severe cases might end in severe pneumonia, acute respiratory distress syndrome (ARDS), septic shock and death due to multiorgan damage, so early recognition of patients with suspected COVID-19 infection is crucial. The burden of the virus is not limited to physical damage, but it also has a significant impact on the mental health of the public. It can lead to generalized anxiety disorders and depression during COVID-19 pandemic. Now many countries are in a state of crisis worldwide. Whenever the living environment changes, people feel unsafe. People's fear of COVID-19 makes them refrain from going to medical centers, which significantly impacts their access to medical care while they require acute treatment. COVID-19 outbreak in countries has pulled essential medical resources away from regular procedures. This has caused complications for patients who need treatment for other medical conditions that require timely and appropriate care. Cancer patients especially still require attention in curative or palliative settings, and women will still be delivering their infants. How can we care for these patients without exposing them to COVID-19?
    Keywords covid19
    Subject code 610
    Language English
    Publishing date 2020-05-17
    Publisher Tehran University of Medical Sciences
    Publishing country ir
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Disruption in Medical Care of Non-COVID Patients in COVID-19 Pandemic

    Allameh, Seyed Farshad / Shateri Amiri, Bahareh / Zarei Jalalabadi, Narjes

    Advanced Journal of Emergency Medicine; Vol 4 No 2s (2020): COVID-19; e45 ; 2588-400X ; 10.22114/ajem.v4i2s

    2020  

    Abstract: In December 2019, a novel coronavirus (2019-nCoV) was detected in Wuhan Hubei province, China. The virus has caused a global concern because of its high potential for transmission, high morbidity and mortality. COVID-19 spreads so rapidly across an ... ...

    Abstract In December 2019, a novel coronavirus (2019-nCoV) was detected in Wuhan Hubei province, China. The virus has caused a global concern because of its high potential for transmission, high morbidity and mortality. COVID-19 spreads so rapidly across an increasing number of countries worldwide that it has been found in more than 200 countries so far. The World Health Organization (WHO) has declared COVID-19 a pandemic and public health threat. In general, COVID-19 is an infectious disease caused bysevere acute respiratory syndrome coronavirus 2(SARS-CoV-2). A case fatality rate of approximately 2.3% has been reported for COVID-19. New fever, cough, lymphopenia and bilateral lung infiltrations are characteristic but not diagnostic for COVID-19. Sore throat, dyspnea, myalgia, diarrhea, and abdominal pain are other presentations of COVID-19. We should also be attentive to the probability of atypical presentations in patients who are immunocompromised. While the majority of cases result in mild respiratory tract symptoms like acute bronchitis, severe cases might end in severe pneumonia, acute respiratory distress syndrome (ARDS), septic shock and death due to multiorgan damage, so early recognition of patients with suspected COVID-19 infection is crucial. The burden of the virus is not limited to physical damage, but it also has a significant impact on the mental health of the public. It can lead to generalized anxiety disorders and depression during COVID-19 pandemic. Now many countries are in a state of crisis worldwide. Whenever the living environment changes, people feel unsafe. People's fear of COVID-19 makes them refrain from going to medical centers, which significantly impacts their access to medical care while they require acute treatment. COVID-19 outbreak in countries has pulled essential medical resources away from regular procedures. This has caused complications for patients who need treatment for other medical conditions that require timely and appropriate care. Cancer patients especially still require attention in curative or palliative settings, and women will still be delivering their infants. How can we care for these patients without exposing them to COVID-19?
    Keywords covid19
    Subject code 610
    Language English
    Publishing date 2020-05-17
    Publisher Tehran University of Medical Sciences
    Publishing country ir
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: Twelve Lessons on Hospital Leadership during COVID-19 Pandemic.

    Allameh, Seyed Farshad / Khajavirad, Nasim / Labaf, Ali / Mirzazadeh, Azim / Sadeghniiat-Haghighi, Khosro / Mortazavi, Sm Javad / Jafarian, Ali

    The archives of bone and joint surgery

    2020  Volume 8, Issue Suppl1, Page(s) 277–280

    Abstract: Coronavirus pandemic has been announced by World Health Organization Director General on March 11th, 2020. Imam Khomeini Hospital Complex, affiliated to Tehran University of Medical Sciences, was one the first referral hospitals in the capital city of ... ...

    Abstract Coronavirus pandemic has been announced by World Health Organization Director General on March 11th, 2020. Imam Khomeini Hospital Complex, affiliated to Tehran University of Medical Sciences, was one the first referral hospitals in the capital city of Tehran, I.R.Iran that entered the crisis and started a serious battle with the disease. The hospital had to change many routine operations to cope with the situation and during this journey, we used published leadership principles and reached to some new experiences. As this is probably the most severe health-related crisis in Iran in the past 100 years, we gathered our lessons learned in the first fifty days of epidemic from the leadership point of view to share those with all colleagues worldwide. We know that leadership is of pivotal role in such a massive crisis and focused leadership experiences can help health care providers to manage the crisis while we are in the middle of it.
    Keywords covid19
    Language English
    Publishing date 2020-06-23
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2782053-1
    ISSN 2345-461X ; 2345-4644
    ISSN (online) 2345-461X
    ISSN 2345-4644
    DOI 10.22038/abjs.2020.47829.2363
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Validity of a Serological Diagnostic Kit for SARS-CoV-2 Available in Iran.

    Shamsollahi, Hamid Reza / Amini, Mostafa / Alizadeh, Shaban / Nedjat, Saharnaz / Akbari-Sari, Ali / Rezaei, Mehdi / Allameh, Seyed Farshad / Fotouhi, Akbar / Yunesian, Masud

    Archives of Iranian medicine

    2020  Volume 23, Issue 9, Page(s) 629–632

    Abstract: Background: The Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic broke out in December 2019 and is now characterized as a pandemic. Effective control of this infectious disease requires access to diagnostic techniques, for both case ...

    Abstract Background: The Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic broke out in December 2019 and is now characterized as a pandemic. Effective control of this infectious disease requires access to diagnostic techniques, for both case finding and epidemic size estimation. The molecular technique is routinely used worldwide. Although it is the "standard" case detection and management method, it has its own shortcomings. Thus, some easy-to-use rapid serological tests have been developed.
    Methods: One hundred and fourteen positive RT-PCR-diagnosed patients were tested by VivaDiag Kit, a brand of rapid serological kits available in hospitals affiliated to Tehran University of Medical Sciences (TUMS), Tehran, Iran. Frozen serum specimens taken from healthy people in summer and fall 2019 were also tested as negative controls.
    Results: Test sensitivity was 47.9% (95% confidence interval [CI]: 38.8-56.9) for IgM and 47.0% (95% CI: 38.0-56.0) for IgG. There was no difference between IgG and IgM seropositivity except in one case. Specificity was calculated as 99.0% (95% CI: 96.4-99.9) for IgM and of 100.0% (95% CI: 0.98.2-100.0) for IgG. Sensitivity was higher in men and older participants.
    Conclusion: This test can be used for epidemiological investigations, especially for the estimation of the level of infection in the community, after it is properly corrected for sensitivity and specificity. The low sensitivity could be attributed to the technical limitations of the kit or low levels of antibodies after infection. The different sensitivity in age and sex groups supports the hypothesis that different people show different immune responses to this virus.
    MeSH term(s) Adult ; Antibodies, Viral/analysis ; Betacoronavirus/immunology ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques/methods ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Female ; Humans ; Incidence ; Iran/epidemiology ; Male ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/epidemiology ; SARS-CoV-2 ; Serologic Tests/methods
    Chemical Substances Antibodies, Viral
    Keywords covid19
    Language English
    Publishing date 2020-09-01
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2204979-4
    ISSN 1735-3947 ; 1029-2977
    ISSN (online) 1735-3947
    ISSN 1029-2977
    DOI 10.34172/aim.2020.75
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: EFFECTIVE DOSE FOR RADIOLOGICAL PROCEDURES IN AN EMERGENCY DEPARTMENT: A CROSS-SECTIONAL STUDY.

    Naseri, Maryam / Shahsavan, Mohammad / Salahshour, Faeze / Peiman, Soheil / Allameh, Seyed Farshad / Farzanehfar, Saeed / Emami-Ardekani, Ali Reza / Pouraliakbar, Hamidreza / Abbasi, Mehrshad

    Radiation protection dosimetry

    2020  Volume 189, Issue 1, Page(s) 63–68

    Abstract: The extent of radiation exposure in emergency settings is not well documented; here, the corresponding effective dose (ED) is provided. In 500 patients admitted in row to the emergency department, ED was compared in patients according to complaints and ... ...

    Abstract The extent of radiation exposure in emergency settings is not well documented; here, the corresponding effective dose (ED) is provided. In 500 patients admitted in row to the emergency department, ED was compared in patients according to complaints and their visiting physicians. Out of all, 220 patients aged 43.5 ± 22.2 years (admission: 2.0 ± 1.6 days) had at least an imaging. The main reasons for admission were trauma (10.5%) and then orthopedic problems (8.6%). EDs from CT and radiography were 1.66 ± 3.59 and 0.71 ± 1.67 mSv, respectively (from all 2.29 ± 4.12). Patients with abdominal (5.8 ± 5.2 mSv; p < 0.002) and pelvic (12.0 ± 6.3 mSv; p < 0.007) complaints received higher ED from CT and radiography and, also, patients visited by surgeons (7.94 ± 6.9 mSv). CT scan was the main source for ED to patients. Irrespective of the final diagnosis, patients with abdominopelvic complaints and those visited by surgeons are at higher exposure risk.
    MeSH term(s) Cross-Sectional Studies ; Emergency Service, Hospital ; Humans ; Radiation Dosage ; Radiation Exposure ; Tomography, X-Ray Computed
    Language English
    Publishing date 2020-01-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 225912-6
    ISSN 1742-3406 ; 0144-8420
    ISSN (online) 1742-3406
    ISSN 0144-8420
    DOI 10.1093/rpd/ncaa013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Positive Perspectives of the Predicament of COVID-19

    Abbaszadeh, Mahsa / Allameh, Seyed Farshad / Sadeghniiat Haghighi, Khosro / RaeesKarami, Seyed Reza / Karimpour Reihan, Sahar

    Advanced Journal of Emergency Medicine; Vol 4 No 2s (2020): COVID-19 ; 2588-400X

    2020  

    Abstract: Although crises such as pandemic can inflict cascading disasters on a health care system, they can provide opportunities for the emergence of new types of potential and their optimal use and manifesting the best kinds of altruism and philanthropy. The ... ...

    Abstract Although crises such as pandemic can inflict cascading disasters on a health care system, they can provide opportunities for the emergence of new types of potential and their optimal use and manifesting the best kinds of altruism and philanthropy. The COVID-19 crisis will undoubtedly entail great costs that are both economically and emotionally irretrievable; nevertheless, the present study seeks to highlight the new opportunities that are provided during this disaster and the optimal utilization of all capacities to alleviate this seemingly-terrible condition. This paper presents a brief report of the first weeks of the COVID-19 crisis in Imam Khomeini Hospital Complex (IKHC) affiliated to Tehran University of Medical Sciences as the largest hospital in Iran with approximately 1200 active beds. In addition to lots of problems during the battle for maintaining the treatment quality in this crisis, a strategy was devised to mitigate the challenges. The positive perspectives during the fight with the predicament of COVID-19 in this hospital are detailed in the following nine domains.
    Keywords covid19
    Subject code 360
    Language English
    Publishing date 2020-05-17
    Publisher Tehran University of Medical Sciences
    Publishing country ir
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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