Article ; Online: Evaluating the Effect of Maternal Opioid Maintenance Dose on the NOWS-COS Outcome Criteria: A Pilot Study.
2024 , Page(s) 99228241246647
Abstract: This retrospective cohort study included 77 mother-infant dyads that delivered term pregnancies at a single tertiary care institution. The primary objective was to investigate whether maternal dose of opioid maintenance therapy during pregnancy affects ... ...
Abstract | This retrospective cohort study included 77 mother-infant dyads that delivered term pregnancies at a single tertiary care institution. The primary objective was to investigate whether maternal dose of opioid maintenance therapy during pregnancy affects infant outcomes. All infants had prenatal exposure to opioid maintenance therapies. Maternal dose was converted into morphine milligram equivalents (MMEs) and stratified into high- (MME >1000 mg) and low-dose groups (MME ≤1000 mg). Associations between infant outcomes and MME dosage were examined using Wilcoxon rank-sum and Fisher's Exact tests. Days to symptom control were significantly higher in the high MME group (5 days vs 2.8 days, |
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Language | English |
Publishing date | 2024-04-17 |
Publishing country | United States |
Document type | Journal Article |
ZDB-ID | 207678-0 |
ISSN | 1938-2707 ; 0009-9228 |
ISSN (online) | 1938-2707 |
ISSN | 0009-9228 |
DOI | 10.1177/00099228241246647 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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