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  1. Article ; Online: A retrospective study of vector borne disease prevalence among anemic dogs in North Carolina

    Katie L. Anderson / Adam Birkenheuer / George E. Moore / Allison Kendall

    PLoS ONE, Vol 18, Iss

    2023  Volume 11

    Keywords Medicine ; R ; Science ; Q
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: A retrospective study of vector borne disease prevalence among anemic dogs in North Carolina.

    Katie L Anderson / Adam Birkenheuer / George E Moore / Allison Kendall

    PLoS ONE, Vol 18, Iss 11, p e

    2023  Volume 0293901

    Abstract: Background Anemia is an important cause of morbidity and mortality in dogs. Further understanding of the prevalence of vector borne diseases (VBD) in anemic dogs is needed. Objectives The objective of this retrospective study was to describe the rate of ... ...

    Abstract Background Anemia is an important cause of morbidity and mortality in dogs. Further understanding of the prevalence of vector borne diseases (VBD) in anemic dogs is needed. Objectives The objective of this retrospective study was to describe the rate of exposure to or infection with VBD among anemic dogs presented to a teaching hospital in North Carolina and to further characterize the anemia in dogs with VBD exposure. Animals A total of 597 anemic dogs that were concurrently tested for VBD were examined at a referral veterinary hospital between January 2012 and December 2018. Methods Retrospective descriptive study. Demographic, clinicopathologic, and VBD testing data were obtained from medical records. Results Of the 597 anemic dogs examined, 180 (30.15%; 95% CI: 26.49-34.01%) tested positive for one or more VBD. There was no difference in the severity of anemia or the proportion of dogs displaying a regenerative anemia between dogs testing positive and negative for VBD. Conclusions A large proportion of anemic dogs from this region test positive for exposure to or infection with VBD. Our study supported the use of PCR and serology run in parallel to maximize the chance of detecting exposure to or infection with VBD compared to either serology or PCR alone. At this time, it is unknown whether infection with VBD contributed to the development of anemia in these patients. However, given the prevalence of VBD exposure in anemic dogs, testing for VBD in anemic patients from this region of the United States is warranted.
    Keywords Medicine ; R ; Science ; Q
    Subject code 630
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Idiopathic functional urinary outflow tract obstruction in dogs, a retrospective case series (2010‐2021)

    Kathrina Mathews / Christine Toedebusch / Carrie Palm / Allison Kendall / Jodi L. Westropp

    Journal of Veterinary Internal Medicine, Vol 37, Iss 6, Pp 2211-

    31 cases

    2023  Volume 2218

    Abstract: Abstract Background Idiopathic functional urinary outflow tract obstruction (iFUOTO) is an uncommon but life‐limiting disease whose etiology and clinical course of disease remain poorly understood. Objective Characterize signalment, clinical signs, ... ...

    Abstract Abstract Background Idiopathic functional urinary outflow tract obstruction (iFUOTO) is an uncommon but life‐limiting disease whose etiology and clinical course of disease remain poorly understood. Objective Characterize signalment, clinical signs, clinicopathologic findings, treatments, and propose a standardized response score for dogs with iFUOTO. Animals Thirty‐one client‐owned dogs diagnosed with iFUOTO. Methods Retrospective case series. Medical records from 2010 to 2021 were reviewed and findings recorded. Dogs were categorized based on the presence or absence of overt signs of neurological disease. Response to treatment was scored. Results Thirty‐one dogs were included. All dogs had stranguria and 14 (45%) had overflow urinary incontinence. Mean age of onset for signs was 6.9 years±8 months. Twenty‐four dogs (77%) were castrated males, 5 (16%) intact males, and 2 (6%) spayed females. Eight (26%) of dogs had overt neurological deficits. Follow‐up data were available for 29 dogs (median 38 days, range: 2‐1277). Final outcome scores were not significantly different among dogs with overt signs of neurological disease (median score 2.5; range: 0‐3) and those without (median score 1; range; 0‐3; P = .35). Treatments included alpha antagonists, skeletal muscle relaxants, parasympathomimetics, anti‐inflammatories, castration, temporary placement of a urethral catheter, or a combination of these. Conclusions and Clinical Relevance Multimodal treatment was frequently prescribed, but a standard outcome score is needed to evaluate the effectiveness of these therapies. Serial neurological examinations and monitoring of the dogs' dysuria are warranted.
    Keywords renal/canine ; urethral obstruction ; urinary tract ; Veterinary medicine ; SF600-1100
    Subject code 630
    Language English
    Publishing date 2023-11-01T00:00:00Z
    Publisher Wiley
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Influence of three different closure techniques on leakage pressures and leakage location following partial cystectomies in normal dogs

    Jason M. Haas / Daniel J. Duffy / Allison Kendall / Yi‐Jen Chang / George E. Moore

    Veterinary Medicine and Science, Vol 9, Iss 4, Pp 1513-

    2023  Volume 1520

    Abstract: Abstract Background Transitional cell carcinoma (TCC) is the most common neoplasia affecting the canine urinary bladder. Partial cystectomy, when used adjuctively with medical management, has been shown to meaningfully extend medial survival time. ... ...

    Abstract Abstract Background Transitional cell carcinoma (TCC) is the most common neoplasia affecting the canine urinary bladder. Partial cystectomy, when used adjuctively with medical management, has been shown to meaningfully extend medial survival time. Surgical stapling devices have a wide variety of uses and advantages over traditional closure methods and, to date, investigation into their use in canine partial cystectomies has not been documented. Objective To determine the influence of three closure techniques on ex vivo leakage pressures and leakage location following canine partial cystectomy. Methods Specimens were assigned to one of three closure techniques: simple continuous appositional closure with 3‐0 suture, closure with a 60 mm gastrointestinal stapler with a 3.5 mm cartridge, and placement of a Cushing suture to augment the stapled closure, with each group containing 12 specimens. Mean initial leakage pressure (ILP), maximum leakage pressure (MLP), and leakage location at the time that ILP was recorded were compared between groups. Results Oversewn stapled constructs leaked at significantly higher ILP (28.5 mmHg) than those in the sutured (17 mmHg) or stapled (22.8 mmHg) group, respectively. MLP was greater in the oversewn stapled construct group compared to other groups. Leakage was detected in 97% partial cystectomies, with leakage occurring from the needle holes in 100% of the sutured closure group, from the staple holes in 100% of the stapled only group, and from the incisional line in 83% and from bladder wall rupture in 8% of the augmented staple closure group. All closure methods withstood normal physiologic cystic pressures. Conclusions Placement of a Cushing suture to augment stapled closures improved the ability of partial cystectomies to sustain higher intravesicular pressures compared with sutured or stapled bladder closures alone. Further in vivo studies are required to determine the clinical significance of these findings and the role of stapling equipment for partial cystectomy, as well ...
    Keywords canine ; closure techniques ; leakage pressures ; partial cystectomies ; Veterinary medicine ; SF600-1100
    Subject code 630
    Language English
    Publishing date 2023-07-01T00:00:00Z
    Publisher Wiley
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Three‐dimensional bladder ultrasound to measure daily urinary bladder volume in hospitalized dogs

    Edward J. Vasquez / Allison Kendall / Sarah Musulin / Shelly L. Vaden

    Journal of Veterinary Internal Medicine, Vol 35, Iss 5, Pp 2256-

    2021  Volume 2262

    Abstract: Abstract Background Urinary bladder volume (UBV) and urine residual volume (URV) provide important information for hospitalized dogs and might allow recognition of urine retention. Objective Using 3‐dimensional (3D) ultrasound to monitor daily URV is a ... ...

    Abstract Abstract Background Urinary bladder volume (UBV) and urine residual volume (URV) provide important information for hospitalized dogs and might allow recognition of urine retention. Objective Using 3‐dimensional (3D) ultrasound to monitor daily URV is a safe and effective way to recognize urinary retention. Animals Twenty‐five client‐owned hospitalized dogs. Methods Prospective, observational study. UBV and URV were measured using 3D ultrasound daily at approximately the same time. UBV was measured, the dog was taken for a 5‐minute controlled leash walk, then URV was estimated. Concurrent use of opioids, anesthetics, and fluids administered IV were recorded. Results Daily URVs were >0.4 mL/kg in 22 of 25 dogs on at least 1 day of hospitalization. Seventeen of 25 dogs had an abnormal URV at the time of discharge. Of 18 dogs that were anesthetized while hospitalized, 16 had a URV >0.4 mL/kg with a mean of 4.34 mL/kg (range, 0.5‐13.4 mL/kg). No statistical difference in degree of URV was found based on the use of anesthesia, administration of fluids IV, or opioids. Weight was significantly associated with URV; dogs <10 kg had a higher URV per unit mass than dogs >10 kg (P = .001). Conclusions and Clinical Importance Use of a 3D ultrasound device to measure daily UBV and URV in hospitalized dogs provides a safe estimate of bladder volume in real‐time. Monitoring daily URV might help in early identification of patients that are retaining urine, thereby preventing potential adverse effects of urethral catheterization or prolonged urinary retention.
    Keywords bladder volume ; dogs ; ultrasound ; urine ; urine residual volume ; Veterinary medicine ; SF600-1100
    Subject code 630
    Language English
    Publishing date 2021-09-01T00:00:00Z
    Publisher Wiley
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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