LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 7 of total 7

Search options

  1. Article ; Online: Physician's Burnout during the COVID-19 Pandemic: A Systematic Review and Meta-Analysis.

    Alkhamees, Abdulmajeed A / Aljohani, Moath S / Kalani, Simindokht / Ali, Amira Mohammed / Almatham, Fahad / Alwabili, Afnan / Alsughier, Naif Abdullah / Rutledge, Thomas

    International journal of environmental research and public health

    2023  Volume 20, Issue 5

    Abstract: The burnout rate among physicians is expected to be higher during COVID-19 period due to the additional sources of physical and emotional stressors. Throughout the current COVID-19 pandemic, numerous studies have evaluated the impacts of COVID-19 on ... ...

    Abstract The burnout rate among physicians is expected to be higher during COVID-19 period due to the additional sources of physical and emotional stressors. Throughout the current COVID-19 pandemic, numerous studies have evaluated the impacts of COVID-19 on physicians' burnout, but the reported results have been inconsistent. This current systematic review and meta-analysis aims to assess and estimate the epidemiology of burnout and the associated risk factors during the COVID-19 pandemic among physicians. A systematic search for studies targeting physicians' burnout was conducted using PubMed, Scopus, ProQuest, Cochrane COVID-19 registry, and pre-print services (PsyArXiv and medRχiv) for English language studies published within the time period of 1 January 2020 to 1 September 2021. Search strategies resulted in 446 possible eligible studies. The titles and abstracts of these studies were screened, which resulted in 34 probable studies for inclusion, while 412 studies were excluded based on the predetermined inclusion criteria. These 34 studies went through a full-text screening for eligibility, which resulted in 30 studies being included in the final reviews and subsequent analyses. Among them, the prevalence of physicians' burnout rate ranged from 6.0-99.8%. This wide variation could be due to the heterogeneity among burnout definitions, different applied assessment tools, and even cultural factors. Further studies may consider other factors when assessing burnout (e.g., the presence of a psychiatric disorders, other work-related and cultural factors). In conclusion, a consistent diagnostic indices for the assessment of burnout is required to enable consistent methods of scoring and interpretation.
    MeSH term(s) Humans ; Pandemics ; COVID-19/epidemiology ; Burnout, Professional/epidemiology ; Physicians/psychology ; Prevalence
    Language English
    Publishing date 2023-03-05
    Publishing country Switzerland
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Review
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph20054598
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Corrigendum to "Cognitive impairment as measured by the THINC-integrated tool (THINC-it): The association with self-reported anxiety in major depressive disorder" [J. Affect. Disord.. 238, 2018, pages 228-232].

    Cha, Danielle S / Carmona, Nicole E / Rodrigues, Nelson B / Mansur, Rodrigo B / Lee, Yena / Subramaniapillai, Mehala / Phan, Lee / Cha, Rebekah H / Pan, Zihang / Lee, Jae Hon / Lee, JungGoo / Almatham, Fahad / Alageel, Asem / Rosenblat, Joshua D / Shekotikhina, Margarita / Rong, Carola / Harrison, John / McIntyre, Roger S

    Journal of affective disorders

    2023  Volume 340, Page(s) 71

    Language English
    Publishing date 2023-08-07
    Publishing country Netherlands
    Document type Published Erratum
    ZDB-ID 135449-8
    ISSN 1573-2517 ; 0165-0327
    ISSN (online) 1573-2517
    ISSN 0165-0327
    DOI 10.1016/j.jad.2023.07.062
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1485: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Drug-drug interactions as a result of co-administering Δ

    Rong, Carola / Carmona, Nicole E / Lee, Yena L / Ragguett, Renee-Marie / Pan, Zihang / Rosenblat, Joshua D / Subramaniapillai, Mehala / Shekotikhina, Margarita / Almatham, Fahad / Alageel, Asem / Mansur, Rodrigo / Ho, Roger C / McIntyre, Roger S

    Expert opinion on drug safety

    2017  Volume 17, Issue 1, Page(s) 51–54

    Abstract: Introduction: To determine, via narrative, non-systematic review of pre-clinical and clinical studies, whether the effect of cannabis on hepatic biotransformation pathways would be predicted to result in clinically significant drug-drug interactions ( ... ...

    Abstract Introduction: To determine, via narrative, non-systematic review of pre-clinical and clinical studies, whether the effect of cannabis on hepatic biotransformation pathways would be predicted to result in clinically significant drug-drug interactions (DDIs) with commonly prescribed psychotropic agents.
    Areas covered: A non-systematic literature search was conducted using the following databases: PubMed, PsycInfo, and Scopus from inception to January 2017. The search term cannabis was cross-referenced with the terms drug interactions, cytochrome, cannabinoids, cannabidiol, and medical marijuana. Pharmacological, molecular, and physiologic studies evaluating the pharmacokinetics of Δ
    Expert opinion: Δ
    MeSH term(s) Cannabidiol/administration & dosage ; Cannabidiol/adverse effects ; Cannabidiol/pharmacology ; Cytochrome P-450 Enzyme Inhibitors/administration & dosage ; Cytochrome P-450 Enzyme Inhibitors/adverse effects ; Cytochrome P-450 Enzyme Inhibitors/pharmacology ; Cytochrome P-450 Enzyme System/drug effects ; Cytochrome P-450 Enzyme System/metabolism ; Dronabinol/administration & dosage ; Dronabinol/adverse effects ; Dronabinol/pharmacology ; Drug Interactions ; Humans ; Psychotropic Drugs/administration & dosage ; Psychotropic Drugs/adverse effects ; Psychotropic Drugs/pharmacology
    Chemical Substances Cytochrome P-450 Enzyme Inhibitors ; Psychotropic Drugs ; Cannabidiol (19GBJ60SN5) ; Dronabinol (7J8897W37S) ; Cytochrome P-450 Enzyme System (9035-51-2)
    Language English
    Publishing date 2017-10-31
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2088728-0
    ISSN 1744-764X ; 1474-0338
    ISSN (online) 1744-764X
    ISSN 1474-0338
    DOI 10.1080/14740338.2017.1397128
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6096: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Perceived sleep quality predicts cognitive function in adults with major depressive disorder independent of depression severity.

    Cha, Danielle S / Carmona, Nicole / Cha, Rebekah H / Zhou, Aileen J / Subramaniapillai, Mehala / Mansur, Rodrigo B / Lee, Yena / Lee, Jae Hon / Lee, JungGoo / Almatham, Fahad / Alageel, Asem / Rosenblat, Joshua D / Shekotikhina, Margarita / Rong, Carola / Harrison, John / McIntyre, Roger S

    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists

    2018  Volume 31, Issue 1, Page(s) 17–26

    Abstract: Background: The aim of this study was to examine the role of perceived sleep quality in predicting subjective as well as objective cognitive function in adults with major depressive disorder (MDD).: Methods: Adults with recurrent MDD (n = 100) ... ...

    Abstract Background: The aim of this study was to examine the role of perceived sleep quality in predicting subjective as well as objective cognitive function in adults with major depressive disorder (MDD).
    Methods: Adults with recurrent MDD (n = 100) experiencing a major depressive episode of at least moderate severity and age-, sex-, and education-matched healthy controls (HC) (n = 100) were recruited to participate in a clinical trial validating the THINC-integrated tool (THINC-it; NCT02508493) for cognitive function. The THINC-it includes subjective and objective measures of cognitive function. Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI).
    Results: Compared with HC, individuals with MDD reported significantly poorer sleep quality, as assessed by domain and global PSQI scores (all
    Conclusions: The results indicate that the subjective and objective cognitive impairments are differentially related to perceived sleep quality and depression severity and emphasize the importance of treating sleep disturbances in MDD.
    MeSH term(s) Adult ; Cognition/physiology ; Depressive Disorder, Major/psychology ; Female ; Humans ; Male ; Neuropsychological Tests/statistics & numerical data ; Recurrence ; Sleep Initiation and Maintenance Disorders/psychology ; Surveys and Questionnaires
    Language English
    Publishing date 2018-10-29
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 1025337-3
    ISSN 1547-3325 ; 1040-1237
    ISSN (online) 1547-3325
    ISSN 1040-1237
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2779: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Characterizing, Assessing, and Treating Cognitive Dysfunction in Major Depressive Disorder.

    McIntyre, Roger S / Lee, Yena / Carmona, Nicole E / Subramaniapillai, Mehala / Cha, Danielle S / Lee, JungGoo / Lee, Jae-Hon / Alageel, Asem / Rodrigues, Nelson B / Park, Caroline / Ragguett, Renee-Marie / Rosenblat, Joshua E / Almatham, Fahad / Pan, Zihang / Rong, Carola / Mansur, Rodrigo B

    Harvard review of psychiatry

    2018  Volume 26, Issue 5, Page(s) 241–249

    Abstract: Learning objectives: After participating in this activity, learners should be better able to:• Characterize cognitive dysfunction in patients with major depressive disorder.• Evaluate approaches to treating cognitive dysfunction in patients with major ... ...

    Abstract Learning objectives: After participating in this activity, learners should be better able to:• Characterize cognitive dysfunction in patients with major depressive disorder.• Evaluate approaches to treating cognitive dysfunction in patients with major depressive disorder.
    Abstract: Cognitive dysfunction is a core psychopathological domain in major depressive disorder (MDD) and is no longer considered to be a pseudo-specific phenomenon. Cognitive dysfunction in MDD is a principal determinant of patient-reported outcomes, which, hitherto, have been insufficiently targeted with existing multimodal treatments for MDD. The neural structures and substructures subserving cognitive function in MDD overlap with, yet are discrete from, those subserving emotion processing and affect regulation. Several modifiable factors influence the presence and extent of cognitive dysfunction in MDD, including clinical features (e.g., episode frequency and illness duration), comorbidity (e.g., obesity and diabetes), and iatrogenic artefact. Screening and measurement tools that comport with the clinical ecosystem are available to detect and measure cognitive function in MDD. Notwithstanding the availability of select antidepressants capable of exerting procognitive effects, most have not been sufficiently studied or rigorously evaluated. Promising pharmacological avenues, as well as psychosocial, behavioral, chronotherapeutic, and complementary alternative approaches, are currently being investigated.
    MeSH term(s) Cognitive Dysfunction/diagnosis ; Cognitive Dysfunction/etiology ; Cognitive Dysfunction/physiopathology ; Cognitive Dysfunction/therapy ; Depressive Disorder, Major/complications ; Depressive Disorder, Major/diagnosis ; Depressive Disorder, Major/physiopathology ; Depressive Disorder, Major/therapy ; Humans
    Language English
    Publishing date 2018-09-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1174775-4
    ISSN 1465-7309 ; 1067-3229
    ISSN (online) 1465-7309
    ISSN 1067-3229
    DOI 10.1097/HRP.0000000000000171
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 3888: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Cognitive impairment as measured by the THINC-integrated tool (THINC-it): The association with self-reported anxiety in Major Depressive Disorder.

    Cha, Danielle S / Carmona, Nicole E / Rodrigues, Nelson B / Mansur, Rodrigo B / Lee, Yena / Subramaniapillai, Mehala / Phan, Lee / Cha, Rebekah H / Pan, Zihang / Lee, Jae Hon / Lee, JungGoo / Almatham, Fahad / Alageel, Asem / Rosenblat, Joshua D / Shekotikhina, Margarita / Rong, Carola / Harrison, John / McIntyre, Roger S

    Journal of affective disorders

    2018  Volume 238, Page(s) 228–232

    Abstract: Background and objectives: This study evaluated the association between self-reported anxiety and objective/subjective measures of cognitive performance in adults with Major Depressive Disorder (MDD).: Methods: Acutely depressed subjects with ... ...

    Abstract Background and objectives: This study evaluated the association between self-reported anxiety and objective/subjective measures of cognitive performance in adults with Major Depressive Disorder (MDD).
    Methods: Acutely depressed subjects with recurrent MDD (n = 100) and age-, sex-, and education-matched healthy controls (HC; n = 100) between the ages of 18 and 65 completed the cross-sectional validation study of the THINC-integrated tool (THINC-it; ClinicalTrials.gov: NCT02508493). Objective cognitive performance was assessed using the THINC-it, and subjective cognitive impairment with the Perceived Deficits Questionnaire for Depression-5-item. Subjects also completed the Generalized Anxiety Disorder-7-item (GAD-7) questionnaire.
    Results: Subjects with MDD reported significantly more anxiety symptoms, as assessed by the GAD-7, compared to HC (p < 0.001). Linear regression analysis determined that anxiety symptoms significantly accounted for 70.4% of the variability in subjective cognitive impairment, adjusting for depression severity. Moreover, subjects' ratings of the difficulties caused by their anxiety were reported as significantly more severe among subjects with MDD when compared to HC (p < 0.001). Likewise, greater self-reported difficulties with anxiety significantly predicted 57.8% of the variability in subjective cognitive impairment, adjusting for depression severity. Neither anxiety symptoms nor impairment due to anxiety symptoms predicted objective cognitive performance.
    Limitations: Subjects were not prospectively verified to have a clinical diagnosis of GAD. Rather, this study examined the relationships between symptoms of generalized anxiety, assessed using a brief screening tool, and subjective and objective cognitive function.
    Conclusions: Results from the current study indicate that adults with MDD and high levels of self-reported anxiety are significantly more likely to report experiencing subjective cognitive dysfunction.
    MeSH term(s) Adult ; Aged ; Anxiety/psychology ; Cognition ; Cognitive Dysfunction/psychology ; Cross-Sectional Studies ; Depressive Disorder, Major/psychology ; Female ; Humans ; Male ; Mass Screening ; Middle Aged ; Recurrence ; Regression Analysis ; Self Report ; Surveys and Questionnaires ; Young Adult
    Language English
    Publishing date 2018-06-01
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 135449-8
    ISSN 1573-2517 ; 0165-0327
    ISSN (online) 1573-2517
    ISSN 0165-0327
    DOI 10.1016/j.jad.2018.05.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1485: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Pain and major depressive disorder: Associations with cognitive impairment as measured by the THINC-integrated tool (THINC-it).

    Cha, Danielle S / Carmona, Nicole E / Mansur, Rodrigo B / Lee, Yena / Park, Hyun Jung / Rodrigues, Nelson B / Subramaniapillai, Mehala / Rosenblat, Joshua D / Pan, Zihang / Lee, Jae Hon / Lee, JungGoo / Almatham, Fahad / Alageel, Asem / Shekotikhina, Margarita / Zhou, Aileen J / Rong, Carola / Harrison, John / McIntyre, Roger S

    Scandinavian journal of pain

    2017  Volume 15, Page(s) 62–67

    Abstract: Objectives: To examine the role of pain on cognitive function in adults with major depressive disorder (MDD).: Methods: Adults (18-65) with a Diagnostic and Statistical Manual - Fifth Edition (DSM-5)-defined diagnosis of MDD experiencing a current ... ...

    Abstract Objectives: To examine the role of pain on cognitive function in adults with major depressive disorder (MDD).
    Methods: Adults (18-65) with a Diagnostic and Statistical Manual - Fifth Edition (DSM-5)-defined diagnosis of MDD experiencing a current major depressive episode (MDE) were enrolled (n
    Results: A significant between-group differences on the VAS was observed (p<0.001), with individuals with MDD reporting higher pain severity as evidenced by higher scores on the VAS than HC. Significant interaction effects were observed between self -rated cognitive deficits and pain ratings (p<0.001) on objective cognitive performance (after adjusting for MADRS total score), suggesting that pain moderates the association between self-rated and objective cognitive function.
    Conclusions: Results indicated that pain is associated with increased self-rated and objective cognitive deficits in adults with MDD.
    Implications: The study herein provides preliminary evidence demonstrating that adults with MDD reporting pain symptomatology and poorer subjective cognitive function is predictive of poorer objective cognitive performance. THINC-it is capable of detecting cognitive dysfunction amongst adults with MDD and pain.
    MeSH term(s) Adolescent ; Adult ; Aged ; Cognition ; Cognitive Dysfunction/diagnosis ; Cognitive Dysfunction/etiology ; Depressive Disorder, Major/complications ; Depressive Disorder, Major/psychology ; Female ; Humans ; Male ; Middle Aged ; Neuropsychological Tests ; Pain/complications ; Pain/psychology ; Prospective Studies ; Young Adult
    Language English
    Publishing date 2017-01-10
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2515451-5
    ISSN 1877-8879 ; 1877-8860
    ISSN (online) 1877-8879
    ISSN 1877-8860
    DOI 10.1016/j.sjpain.2016.12.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top