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  1. Article ; Online: Mobile phones as fomites for pathogenic microbes: A cross-sectional survey of perceptions and sanitization habits of health care workers in Dubai, United Arab Emirates.

    Albastaki, Abdulla / Olsen, Matthew / Almulla, Hanan / Nassar, Rania / Boucherabine, Syrine / Mohamed, Lobna / Almheiri, Reem / Kachigunda, Barbara / McKirdy, Simon / Alghafri, Rashed / Tajouri, Lotti / Senok, Abiola

    Infection, disease & health

    2022  Volume 28, Issue 1, Page(s) 19–26

    Abstract: Backgrounds: In 2022, smartphone use continues to expand with the number of smartphone subscriptions surpassing 6 billion and forecasted to grow to 7.5 billion by 2026. The necessity of these 'high touch' devices as essential tools in professional ... ...

    Abstract Backgrounds: In 2022, smartphone use continues to expand with the number of smartphone subscriptions surpassing 6 billion and forecasted to grow to 7.5 billion by 2026. The necessity of these 'high touch' devices as essential tools in professional healthcare settings carries great risks of cross-contamination between mobile phones and hands. Current research emphasises mobile phones as fomites enhancing the risk of nosocomial disease dissemination as phone sanitisation is often overlooked. To assess and report via a large-scale E-survey the handling practices and the use of phones by healthcare workers.
    Methods: A total of 377 healthcare workers (HCWs) participated in this study to fill in an E-survey online consisting of 14 questions (including categorical, ordinal, and numerical data). Analysis of categorical data used non-parametric techniques such as Pearson's chi-squared test.
    Results: During an 8-h shift, 92.8% (n/N = 350/377) use their phone at work with 84.6% (n/N = 319/377) considering mobile phones as an essential tool for their job. Almost all HCWs who participated in this survey believe their mobile phones could potentially harbour microorganisms (97.1%; n/N = 366/377). Fifty-seven respondents (15.1%) indicated that they use their phones while wearing gloves and 10.3% (n/N = 39/377) have never cleaned their phones. The majority of respondents (89.3%; n/N = 337/377) agreed that contaminated mobile phones could contribute to dissemination of SARS-CoV-2.
    Conclusion: Mobile phone use is now almost universal and indispensable in healthcare. Medical staff believe mobile phones can act as fomites with a potential risk for dissemination of microbes including SARS-COV-2. There is an urgent call for the incorporation of mobile phone sanitisation in infection prevention protocol. Studies on the use of ultraviolet-C based phone sanitation devices in health care settings are needed.
    MeSH term(s) Humans ; Fomites ; Cross-Sectional Studies ; United Arab Emirates ; COVID-19 ; SARS-CoV-2 ; Cell Phone ; Health Personnel
    Language English
    Publishing date 2022-08-19
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2902143-1
    ISSN 2468-0869 ; 2468-0451
    ISSN (online) 2468-0869
    ISSN 2468-0451
    DOI 10.1016/j.idh.2022.07.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Design and development of novel single multiplex system incorporating 26 rapidly mutating Y-STRs; 26 RM Yplex.

    Albastaki, Abdulla / Naji, Mohammed / Lootah, Reem / Almheiri, Reem / Almulla, Hanan / Alreyami, Afra / Almarri, Iman / Yu, Zailiang / Zhang, Yueke / Shu, Chang / Alghafri, Rashed

    Electrophoresis

    2022  Volume 43, Issue 18-19, Page(s) 1911–1919

    Abstract: This article details the development of a single multiplex system amplifying 26 rapidly mutating Y-STR markers. A sequenced allelic ladder, constructed for calling alleles of all loci, is introduced. The multiplex system shows the ability to address the ... ...

    Abstract This article details the development of a single multiplex system amplifying 26 rapidly mutating Y-STR markers. A sequenced allelic ladder, constructed for calling alleles of all loci, is introduced. The multiplex system shows the ability to address the limitations of Y-STRs commercial kits in differentiating closely related males. The multiplex performed well in the prevalidation tests and showed great potential to be used in forensic casework.
    MeSH term(s) Alleles ; Chromosomes, Human, Y/genetics ; DNA Fingerprinting ; Forensic Medicine ; Haplotypes ; Humans ; Male ; Microsatellite Repeats/genetics
    Language English
    Publishing date 2022-08-08
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 619001-7
    ISSN 1522-2683 ; 0173-0835
    ISSN (online) 1522-2683
    ISSN 0173-0835
    DOI 10.1002/elps.202200099
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1868: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: First confirmed detection of SARS-COV-2 in untreated municipal and aircraft wastewater in Dubai, UAE: The use of wastewater based epidemiology as an early warning tool to monitor the prevalence of COVID-19.

    Albastaki, Abdulla / Naji, Mohammed / Lootah, Reem / Almeheiri, Reem / Almulla, Hanan / Almarri, Iman / Alreyami, Afra / Aden, Ahmed / Alghafri, Rashed

    The Science of the total environment

    2020  Volume 760, Page(s) 143350

    Abstract: Severe Acute Respiratory Syndrome - Coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China and spread to more than 114 countries resulting in a pandemic, which was declared by the WHO in March 2020. Tracking the spread of the virus raised a main concern in ... ...

    Abstract Severe Acute Respiratory Syndrome - Coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China and spread to more than 114 countries resulting in a pandemic, which was declared by the WHO in March 2020. Tracking the spread of the virus raised a main concern in every country. Many researches proved the presence of SARS-CoV-2 in stool samples of patients, where the genes of this virus gave a positive signal several days prior to the occurrence of symptoms. The fact of viral shedding in stools provides an advantage in utilizing wastewater systems as a tool to monitor the viral prevalence. We tested more than 2900 municipal wastewater samples coming from 49 distinctive area in Dubai, where 28.6% showed positive results. We also looked into the wastewater samples from 198 commercial aircrafts arriving at Dubai Airport, giving a positive result percentage of 13.6%. The presence of SARS-CoV-2 genes was confirmed using TaqPath™ Covid-19 RT-PCR kit, which targets ORF1ab, N gene and S gene. This project shows the significance of utilizing wastewater-based epidemiology (WBE) in monitoring the prevalence of various infectious diseases such as SARS-CoV-2, which can assist the decision makers to determine the level of precautionary measures according to the areas of the outbreak. With this in mind, pricewise, WBE is considered cost-effective when comparing to clinical nasal swabs.
    MeSH term(s) Aircraft ; COVID-19 ; China/epidemiology ; Humans ; Prevalence ; SARS-CoV-2 ; Wastewater ; Wastewater-Based Epidemiological Monitoring
    Chemical Substances Waste Water
    Keywords covid19
    Language English
    Publishing date 2020-10-29
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2020.143350
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 949: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: First confirmed detection of SARS-COV-2 in untreated municipal and aircraft wastewater in Dubai, UAE: The use of wastewater based epidemiology as an early warning tool to monitor the prevalence of COVID-19

    Albastaki, Abdulla / Naji, Mohammed / Lootah, Reem / Almeheiri, Reem / Almulla, Hanan / Almarri, Iman / Alreyami, Afra / Aden, Ahmed / Alghafri, Rashed

    Sci Total Environ

    Abstract: Severe Acute Respiratory Syndrome - Coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China and spread to more than 114 countries resulting in a pandemic, which was declared by the WHO in March 2020. Tracking the spread of the virus raised a main concern in ... ...

    Abstract Severe Acute Respiratory Syndrome - Coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China and spread to more than 114 countries resulting in a pandemic, which was declared by the WHO in March 2020. Tracking the spread of the virus raised a main concern in every country. Many researches proved the presence of SARS-CoV-2 in stool samples of patients, where the genes of this virus gave a positive signal several days prior to the occurrence of symptoms. The fact of viral shedding in stools provides an advantage in utilizing wastewater systems as a tool to monitor the viral prevalence. We tested more than 2900 municipal wastewater samples coming from 49 distinctive area in Dubai, where 28.6% showed positive results. We also looked into the wastewater samples from 198 commercial aircrafts arriving at Dubai Airport, giving a positive result percentage of 13.6%. The presence of SARS-CoV-2 genes was confirmed using TaqPath™ Covid-19 RT-PCR kit, which targets ORF1ab, N gene and S gene. This project shows the significance of utilizing wastewater-based epidemiology (WBE) in monitoring the prevalence of various infectious diseases such as SARS-CoV-2, which can assist the decision makers to determine the level of precautionary measures according to the areas of the outbreak. With this in mind, pricewise, WBE is considered cost-effective when comparing to clinical nasal swabs.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #894211
    Database COVID19

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  5. Article ; Online: First confirmed detection of SARS-COV-2 in untreated municipal and aircraft wastewater in Dubai, UAE

    Albastaki, Abdulla / Naji, Mohammed / Lootah, Reem / Almeheiri, Reem / Almulla, Hanan / Almarri, Iman / Alreyami, Afra / Aden, Ahmed / Alghafri, Rashed

    Science of The Total Environment

    The use of wastewater based epidemiology as an early warning tool to monitor the prevalence of COVID-19

    2020  , Page(s) 143350

    Keywords Environmental Engineering ; Waste Management and Disposal ; Pollution ; Environmental Chemistry ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2020.143350
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 949: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Roundup causes embryonic development failure and alters metabolic pathways and gut microbiota functionality in non-target species.

    Suppa, Antonio / Kvist, Jouni / Li, Xiaojing / Dhandapani, Vignesh / Almulla, Hanan / Tian, Antoine Y / Kissane, Stephen / Zhou, Jiarui / Perotti, Alessio / Mangelson, Hayley / Langford, Kyle / Rossi, Valeria / Brown, James B / Orsini, Luisa

    Microbiome

    2020  Volume 8, Issue 1, Page(s) 170

    Abstract: Background: Research around the weedkiller Roundup is among the most contentious of the twenty-first century. Scientists have provided inconclusive evidence that the weedkiller causes cancer and other life-threatening diseases, while industry-paid ... ...

    Abstract Background: Research around the weedkiller Roundup is among the most contentious of the twenty-first century. Scientists have provided inconclusive evidence that the weedkiller causes cancer and other life-threatening diseases, while industry-paid research reports that the weedkiller has no adverse effect on humans or animals. Much of the controversial evidence on Roundup is rooted in the approach used to determine safe use of chemicals, defined by outdated toxicity tests. We apply a system biology approach to the biomedical and ecological model species Daphnia to quantify the impact of glyphosate and of its commercial formula, Roundup, on fitness, genome-wide transcription and gut microbiota, taking full advantage of clonal reproduction in Daphnia. We then apply machine learning-based statistical analysis to identify and prioritize correlations between genome-wide transcriptional and microbiota changes.
    Results: We demonstrate that chronic exposure to ecologically relevant concentrations of glyphosate and Roundup at the approved regulatory threshold for drinking water in the US induce embryonic developmental failure, induce significant DNA damage (genotoxicity), and interfere with signaling. Furthermore, chronic exposure to the weedkiller alters the gut microbiota functionality and composition interfering with carbon and fat metabolism, as well as homeostasis. Using the "Reactome," we identify conserved pathways across the Tree of Life, which are potential targets for Roundup in other species, including liver metabolism, inflammation pathways, and collagen degradation, responsible for the repair of wounds and tissue remodeling.
    Conclusions: Our results show that chronic exposure to concentrations of Roundup and glyphosate at the approved regulatory threshold for drinking water causes embryonic development failure and alteration of key metabolic functions via direct effect on the host molecular processes and indirect effect on the gut microbiota. The ecological model species Daphnia occupies a central position in the food web of aquatic ecosystems, being the preferred food of small vertebrates and invertebrates as well as a grazer of algae and bacteria. The impact of the weedkiller on this keystone species has cascading effects on aquatic food webs, affecting their ability to deliver critical ecosystem services. Video Abstract.
    MeSH term(s) Animals ; Daphnia/drug effects ; Embryonic Development/drug effects ; Gastrointestinal Microbiome/drug effects ; Glycine/analogs & derivatives ; Glycine/toxicity ; Metabolic Networks and Pathways/drug effects ; Glyphosate
    Chemical Substances Glycine (TE7660XO1C)
    Language English
    Publishing date 2020-12-15
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2697425-3
    ISSN 2049-2618 ; 2049-2618
    ISSN (online) 2049-2618
    ISSN 2049-2618
    DOI 10.1186/s40168-020-00943-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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