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  1. Article: The Role of Neoadjuvant Therapy in a Giant Gastric Gastrointestinal Stromal Tumour: A Case Report and Review of the Literature.

    Alsaud, Jolan S / Alruqayi, Saja / Alomair, Abdulaziz

    Cureus

    2024  Volume 16, Issue 3, Page(s) e55655

    Abstract: Gastric gastrointestinal stromal tumour (GIST) is a rare disease with an annual incidence of 10 cases per million. Herein, we present the case of a 45-year-old man who visited our clinic with complaints of weight loss and anorexia, without changes in ... ...

    Abstract Gastric gastrointestinal stromal tumour (GIST) is a rare disease with an annual incidence of 10 cases per million. Herein, we present the case of a 45-year-old man who visited our clinic with complaints of weight loss and anorexia, without changes in bowel habits or vomiting, for four months. On physical examination, all vital signs were normal. The abdomen was distended without tenderness and had a giant upper abdominal mass. Tumour marker investigation revealed high levels of cancer antigen 125 with normal levels of alpha-1-fetoprotein, carcinoembryonic antigen, and carbohydrate antigen. A computed tomography (CT) scan showed a mass measuring 35 × 25 × 20 cm, likely originating from the fundus of the stomach. Upper gastrointestinal endoscopy indicated external compression of the stomach and a fundal submucosal mass. Ultrasound-guided biopsy demonstrated the presence of a GIST. There was a severe danger of both the tumour rupturing during surgery and the combined excision of adjacent organs if the surgery was performed with the massive tumour. Therefore, daily neoadjuvant therapy with imatinib 400 mg was administered for three months. Post-therapeutic CT indicated a significant reduction in the size of the mass, which now measured 17 × 14 × 21 cm. The patient underwent surgical resection a month after the completion of neoadjuvant therapy, and the post-operative period was uneventful. He was followed up regularly at the general surgery department for 24 months without recurrence. This case asserts the benefit of neoadjuvant therapy in reducing the tumour size pre-operatively, which enhances the complete resection rate, prevents the need for multi-organ resection, and lowers the risk of surgery.
    Language English
    Publishing date 2024-03-06
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.55655
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Optimization of Mordenite Membranes Using Sucrose Precursor for Pervaporation of Water-Ethanol Mixtures.

    Alomair, Abdulaziz A / Alqaheem, Yousef

    Membranes

    2021  Volume 11, Issue 3

    Abstract: Post-treated mordenite membranes were prepared using sucrose ( ... ...

    Abstract Post-treated mordenite membranes were prepared using sucrose (C
    Language English
    Publishing date 2021-02-25
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2077-0375
    ISSN 2077-0375
    DOI 10.3390/membranes11030160
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Pancreatic Arteriovenous Malformations: A Case From Saudi Arabia.

    Alharbi, Ohud T / Salem, Mayar M / Alotaibi, Daliyah / Alsaud, Jolan S / Almohaimeed, Rayan / Alomair, Abdulaziz

    Cureus

    2024  Volume 16, Issue 3, Page(s) e55340

    Abstract: Arteriovenous malformation (AVM) of the gastrointestinal tract is a rare anomaly, mostly due to congenital reasons. Patients with pancreatic AVM can live without experiencing symptoms. It can present with gastrointestinal bleeding or portal hypertension, ...

    Abstract Arteriovenous malformation (AVM) of the gastrointestinal tract is a rare anomaly, mostly due to congenital reasons. Patients with pancreatic AVM can live without experiencing symptoms. It can present with gastrointestinal bleeding or portal hypertension, and diagnosis can be made by computed tomography (CT) or angiography. CT findings include multiple discrete intrapancreatic vessels. A 48-year-old man complained of abdominal pain with a sensation of fullness that radiated to the back for a month, associated with shortness of breath, loss of appetite, and unintentional weight loss of 33% in one month without nausea or vomiting. On physical examination, the abdomen was soft and lax with epigastric tenderness and a negative Murphy sign. Laboratory investigations showed high amylase with normal liver and kidney functions. CT showed pancreatic AVM. He underwent partial pancreatectomy and splenectomy. After the surgery, the patient reported an improvement in symptoms. All follow-up visits were uneventful. Pancreatic AVM is a rare disease, and the most significant chief complaint of most patients is gastrointestinal tract bleeding. It requires imaging depending on the signs and symptoms. The primary imaging modality is CT, with subtraction angiography for confirmation. Surgical treatment is the standard of management for most patients when tolerable. Additionally, early detection of these rare anomalies can avoid massive gastrointestinal tract bleeding and the development of resistance portal hypertension and can save patients' lives if bleeding occurs.
    Language English
    Publishing date 2024-03-01
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.55340
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Minimizing Solvent Toxicity in Preparation of Polymeric Membranes for Gas Separation.

    Alqaheem, Yousef / Alomair, Abdulaziz A

    ACS omega

    2020  Volume 5, Issue 12, Page(s) 6330–6335

    Abstract: Toxic solvents such as dimethylformamide (DMF) are widely used for the preparation of polymeric membranes due to the strong dissolving power. Environmentally friendly solvents are available, but the developed membranes suffered from low performance due ... ...

    Abstract Toxic solvents such as dimethylformamide (DMF) are widely used for the preparation of polymeric membranes due to the strong dissolving power. Environmentally friendly solvents are available, but the developed membranes suffered from low performance due to the poor solubility of the polymer in the solvent. In this work, polyetherimide membranes were prepared using DMF with the addition of the biodegradable solvent γ-butyrolactone (GBL). Results show that mixing 75 wt % of DMF with 25 wt % GBL enhanced the membrane gas permeability toward hydrogen, methane, helium, carbon dioxide, and nitrogen. The overall permeability was increased by 9.6% compared to the permeability of the membrane made by 100 wt % DMF. Hydrogen-to-methane selectivity was also raised from 26.3 to 29.3.
    Language English
    Publishing date 2020-03-21
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.9b03656
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Microscopy and Spectroscopy Techniques for Characterization of Polymeric Membranes.

    Alqaheem, Yousef / Alomair, Abdulaziz A

    Membranes

    2020  Volume 10, Issue 2

    Abstract: Polymeric membrane is a proven technology for water purification and wastewater treatment. The membrane is also commercialized for gas separation, mainly for carbon dioxide removal and hydrogen recovery. Characterization techniques are excellent tools ... ...

    Abstract Polymeric membrane is a proven technology for water purification and wastewater treatment. The membrane is also commercialized for gas separation, mainly for carbon dioxide removal and hydrogen recovery. Characterization techniques are excellent tools for exploring the membrane structure and the chemical properties. This information can be then optimized to improve the membrane for better performance. In this paper, characterization techniques for studying the physical structure such as scanning electron microscopy (SEM), transmission electron microscopy (TEM), and atomic force microscopy (AFM) are discussed. Techniques for investigating the crystal structure such as X-ray diffraction (XRD), small-angle X-ray scattering (SAXS), and wide-angle X-ray scattering (WAXS) are also considered. Other tools for determining the functional groups such Fourier transform infrared spectroscopy (FTIR), Raman spectroscopy, and nuclear magnetic resonance (NMR) are reviewed. Methods for determining the elemental composition such as energy-dispersion X-ray spectroscopy (EDS), X-ray fluorescent (XRF), and X-ray photoelectron spectroscopy (XPS) are explored. The paper also gives general guidelines for sample preparation and data interpretation for each characterization technique.
    Language English
    Publishing date 2020-02-24
    Publishing country Switzerland
    Document type Journal Article ; Review
    ISSN 2077-0375
    ISSN 2077-0375
    DOI 10.3390/membranes10020033
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Mucinous Cystic Neoplasm of the Pancreas in a Pregnant Woman: A Case Report and Review of the Literature.

    Alomair, Abdulaziz A / Almohaimeed, Rayan A / Alsaud, Jolan S / Alotaibi, Daliyah F / Alharbi, Ohud T

    Cureus

    2023  Volume 15, Issue 4, Page(s) e37787

    Abstract: Mucinous cystic neoplasms of the pancreas are rare tumors that represent 10% of cystic pancreatic tumors. They are potentially sex hormone-sensitive. However, mucinous cystic neoplasms occurring during pregnancy are relatively uncommon. A 33-year-old ... ...

    Abstract Mucinous cystic neoplasms of the pancreas are rare tumors that represent 10% of cystic pancreatic tumors. They are potentially sex hormone-sensitive. However, mucinous cystic neoplasms occurring during pregnancy are relatively uncommon. A 33-year-old woman in her ninth week of gestation was referred to us due to abdominal pain for two months. Magnetic resonance imaging revealed a well-defined unilocular cystic lesion at the tail of the pancreas, measuring 7x6.4 cm. The patient underwent tumor resection with distal pancreatectomy and splenectomy during the second trimester to prevent the potential risk of rupture of the neoplasm, rapid growth, and/or intrauterine growth restriction. Histopathological examination revealed a mucinous cystadenoma with no atypia or malignancy. The patient completely recovered from the surgery and had a healthy full-term baby. This case shows the benefit of performing the surgery during the second trimester compared to the potential risk of delaying the surgery.
    Language English
    Publishing date 2023-04-18
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.37787
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The Implementation of a Carbon Precursor to Produce ZSM-5 Membranes for the Separation of Isomers in the Pervaporation System.

    Alomair, Abdulaziz A / Alqaheem, Yousef

    ACS omega

    2019  Volume 4, Issue 21, Page(s) 19005–19010

    Abstract: The separation ... ...

    Abstract The separation of
    Language English
    Publishing date 2019-11-05
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.9b01871
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: The use of a sucrose precursor to prepare a carbon membrane for the separation of hydrogen from methane

    Alomair, Abdulaziz / Yousef Alqaheem / Stuart M. Holmes

    RSC advances. 2019 Apr. 03, v. 9, no. 19

    2019  

    Abstract: In this study, we present the use of sucrose (C₁₂H₂₂O₁₁), which exists in abundance in nature, to prepare a carbon membrane without any preceding treatments. The preparation procedure was conducted using a low pyrolysis temperature, i.e., in the range of ...

    Abstract In this study, we present the use of sucrose (C₁₂H₂₂O₁₁), which exists in abundance in nature, to prepare a carbon membrane without any preceding treatments. The preparation procedure was conducted using a low pyrolysis temperature, i.e., in the range of 300–500 °C, followed by complete formation of the structure of the carbon membrane. The gas separation characteristics of the resulting membranes were assessed by evaluating both hydrogen and methane permeation. The highest selectivity obtained for H₂/CH₄ was 31.34 with H₂ permeability of 459.24 GPU. The entire fabrication procedure was designed to be economical in order to facilitate any future commercialization.
    Keywords carbon ; commercialization ; hydrogen ; methane ; permeability ; pyrolysis ; sucrose ; temperature
    Language English
    Dates of publication 2019-0403
    Size p. 10437-10444.
    Publishing place The Royal Society of Chemistry
    Document type Article
    ISSN 2046-2069
    DOI 10.1039/c9ra01312a
    Database NAL-Catalogue (AGRICOLA)

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  9. Article ; Online: The use of a sucrose precursor to prepare a carbon membrane for the separation of hydrogen from methane.

    Alomair, Abdulaziz / Alqaheem, Yousef / Holmes, Stuart M

    RSC advances

    2019  Volume 9, Issue 19, Page(s) 10437–10444

    Abstract: In this study, we present the use of sucrose ( ... ...

    Abstract In this study, we present the use of sucrose (C
    Language English
    Publishing date 2019-04-03
    Publishing country England
    Document type Journal Article
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/c9ra01312a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: A novel approach to fabricate zeolite membranes for pervaporation processes

    Alomair, Abdulaziz A / Al-Jubouri, Sama M / Holmes, Stuart M

    Journal of materials chemistry A. 2015 Apr. 28, v. 3, no. 18

    2015  

    Abstract: The conventional methods used in preparing zeolite membranes, such as the secondary growth and in situ crystallization methods, involve long and complex procedures that require the preparation of the zeolite aluminosilicate gel prior to the fabrication ... ...

    Abstract The conventional methods used in preparing zeolite membranes, such as the secondary growth and in situ crystallization methods, involve long and complex procedures that require the preparation of the zeolite aluminosilicate gel prior to the fabrication process and often result in membranes which contain pin holes. Here we report a simple, cheap, and less time-consuming technique to fabricate zeolite A and mordenite membranes on a porous stainless steel support. In addition, the technique makes it possible to fabricate types of zeolite membranes that have been previously difficult to synthesise. A clinoptilolite membrane was fabricated to demonstrate the ability to manufacture a zeolite membrane from an existing crystalline zeolite (natural or synthetic). All three membranes were subjected to separation tests, (ethanol dehydration, ethanol–cyclohexane and phenol removal from water) to demonstrate the efficacy of membrane synthesis. The fluxes obtained and separation factors which were achieved are comparable with literature values but as with most zeolite membranes there is a trade-off between high flux and separation.
    Keywords aluminum silicates ; crystallization ; ethanol ; gels ; manufacturing ; pervaporation ; phenol ; stainless steel ; zeolites
    Language English
    Dates of publication 2015-0428
    Size p. 9799-9806.
    Publishing place The Royal Society of Chemistry
    Document type Article
    ZDB-ID 2702232-8
    ISSN 2050-7496 ; 2050-7488
    ISSN (online) 2050-7496
    ISSN 2050-7488
    DOI 10.1039/c5ta00124b
    Database NAL-Catalogue (AGRICOLA)

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