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  1. Article: Hemolytic Anemia as a Provoking Factor for Recurrent Venous Thromboembolism: A Case Report.

    Demelo-Rodríguez, Pablo / Castañeda-Pérez, Sabela / Alonso-Gonzalo, Leyre / Moragón-Ledesma, Sergio / Galeano-Valle, Francisco

    Cureus

    2024  Volume 16, Issue 2, Page(s) e54361

    Abstract: Warm antibody autoimmune hemolytic anemia (WAIHA) is a rare disease that leads to the destruction of red blood cells in the reticuloendothelial system through the mediation of agglutinins (immunoglobulin G (IgG) type in most cases) that attach to the ... ...

    Abstract Warm antibody autoimmune hemolytic anemia (WAIHA) is a rare disease that leads to the destruction of red blood cells in the reticuloendothelial system through the mediation of agglutinins (immunoglobulin G (IgG) type in most cases) that attach to the erythrocyte wall at 37 °C. The association of WAIHA and venous thromboembolism (VTE) seems to be higher than other hemolytic disorders classically associated with VTE and there is a current investigation aimed at clarifying this association and establishing some criteria to use anticoagulant treatment in patients with WAIHA. Despite this, WAIHA is a rare cause for the development of recurrent VTE under secondary prophylactic anticoagulant treatment, with only a few cases described in the literature. We present the case of a patient who developed a recurrence of deep vein thrombosis during a WAIHA episode despite treatment with acenocoumarol and a review of the literature.
    Language English
    Publishing date 2024-02-17
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.54361
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A retrospective analysis of incidence and severity of COVID-19 among hypertensive patients: the other side.

    Oblitas, Crhistian-Mario / Torres-Do-Rego, Ana / García, Alejandra García / Mato-Jimeno, Víctor / Alonso Gonzalo, Leyre / Luis-García, Sara / Enríquez-Gómez, Andrés / Baltasar-López, Mercedes / Bello-Martínez, Elena

    Clinical and experimental hypertension (New York, N.Y. : 1993)

    2022  Volume 44, Issue 5, Page(s) 459–463

    Abstract: Objective: The role of hypertension in COVID-19 has not been clearly elucidated yet. The aim of this study was to evaluate the incidence and severity of COVID-19 in a hypertensive population and assess whether there is a link between blood pressure ... ...

    Abstract Objective: The role of hypertension in COVID-19 has not been clearly elucidated yet. The aim of this study was to evaluate the incidence and severity of COVID-19 in a hypertensive population and assess whether there is a link between blood pressure control and SARS-CoV-2 infection outcomes.
    Methods: This was a single-center retrospective observational study that evaluated the incidence and severity of COVID-19 in a chronic hypertensive population (n=1,637) from a specialized consultation of Hypertension and Cardiovascular Risk of Internal Medicine in a tertiary hospital in Madrid (Spain).
    Results: A total of 147 COVID-19 patients (9%) were found, with a median age of 59 (±14) years, where 77 (52.4%) patients were male. Forty patients required hospitalization (27.2%), 15 patients had severe COVID-19 (10.2%), and 6 patients died (4.1%). Among the causes of hypertension, 104 (70.7%) patients had essential hypertension and 22 (15%) patients presented primary hyperaldosteronism; and 66 (44.9%) patients presented RH. Severe COVID-19 was associated with age over 65 years (crude OR 4.43 [95% CI 1.3-14.2; p = .012]) and diabetes mellitus (crude OR 4.15 [95% CI 1.3-12.9; p = .014]).
    Conclusion: This study showed a lower rate of incidence, hospitalization, and severity of COVID-19 in the hypertensive population.
    MeSH term(s) Aged ; COVID-19/complications ; COVID-19/epidemiology ; Female ; Hospitalization ; Humans ; Hypertension/complications ; Hypertension/epidemiology ; Incidence ; Male ; Middle Aged ; Retrospective Studies ; Risk Factors ; SARS-CoV-2
    Language English
    Publishing date 2022-05-08
    Publishing country England
    Document type Journal Article ; Observational Study
    ZDB-ID 604757-9
    ISSN 1525-6006 ; 0730-0077
    ISSN (online) 1525-6006
    ISSN 0730-0077
    DOI 10.1080/10641963.2022.2071916
    Database MEDical Literature Analysis and Retrieval System OnLINE

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