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  1. Article ; Online: Pediatric donor heart acceptance practices in the United States: What is really being considered?

    McCulloch, M A / Alonzi, L P / White, S C / Haregu, F / Porter, M D

    Pediatric transplantation

    2023  Volume 28, Issue 1, Page(s) e14649

    Abstract: Background: Recent studies demonstrate high offer decline and organ non-utilization rates are associated with increased pediatric heart transplant waitlist mortality. We sought to determine which donor, candidate, and offer specific variables most ... ...

    Abstract Background: Recent studies demonstrate high offer decline and organ non-utilization rates are associated with increased pediatric heart transplant waitlist mortality. We sought to determine which donor, candidate, and offer specific variables most importantly influenced these decisions using only data available at the time of each offer.
    Methods: Retrospective review of pediatric (<18 years) heart donor offers made to pediatric candidates in the United States between 2010 and 2020. In addition to standard donor, candidate, and offer data available in UNOS, we extracted objective and qualitative valvar and myocardial function data from all available donor echocardiogram reports.
    Results: During the study period, 5625 pediatric donor hearts produced 30 156 offers to 4905 unique candidates, of which 88.7% of all offers were declined and 39.2% of organs were not utilized by pediatric waitlisted candidates. Of the 60.8% utilized hearts, 89.7% had a 'cumulatively' normal echocardiogram at the time of offer acceptance; 62.9% of hearts not utilized for a pediatric candidate also had a cumulatively normal final echocardiogram. Random forest and logistic regression modeling demonstrated good predictive performance (AUROC ≥0.83) of likelihood to accept when utilizing donor, candidate, and offer specific variables. SHAP variable importance scores demonstrated number of prior offer declines and candidate institution's prior year acceptance rates as the two most important variables influencing offer decisions.
    Conclusions: Behavioral economics appear to play a significant role in pediatric heart transplant candidate institutions' acceptance practices, even when considering the arguably healthier pediatric donor population. Removal of prior institution's decisions from DonorNet may help increase donor utilization.
    MeSH term(s) Humans ; Child ; United States ; Tissue Donors ; Heart Transplantation ; Donor Selection ; Retrospective Studies ; Waiting Lists ; Tissue and Organ Procurement
    Language English
    Publishing date 2023-11-27
    Publishing country Denmark
    Document type Journal Article
    ZDB-ID 1390284-2
    ISSN 1399-3046 ; 1397-3142
    ISSN (online) 1399-3046
    ISSN 1397-3142
    DOI 10.1111/petr.14649
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Online: New studies of allowed pion and muon decays

    Pocanic, D. / Palladino, A. / Alonzi, L. P. / Baranov, V. A. / Bertl, W. / Bychkov, M. / Bystritsky, Yu. M. / Frlez, E. / Kalinnikov, V. A. / Khomutov, N. V. / Korenchenko, A. S. / Korenchenko, S. M. / Korolija, M. / Kozlowski, T. / Kravchuk, N. P. / Kuchinsky, N. A. / Lehman, M. C. / Mekterovic, D. / Munyangabe, E. /
    Mzhavia, D. / Robmann, P. / Rozhdestvensky, A. M. / Shkarovskiy, S. N. / Straumann, U. / Supek, I. / Truöl, P. / Tsamalaidze, Z. / van der Schaaf, A. / Velicheva, E. P. / Volnykh, V. P.

    2012  

    Abstract: Building on the rare pion and muon decay results of the PIBETA experiment, the PEN collaboration has undertaken a precise measurement of B_{\pi e2} = R^\pi_{e/\mu}, the \pi^+ -> e^+\nu(\gamma) decay branching ratio, at the Paul Scherrer Institute, to ... ...

    Abstract Building on the rare pion and muon decay results of the PIBETA experiment, the PEN collaboration has undertaken a precise measurement of B_{\pi e2} = R^\pi_{e/\mu}, the \pi^+ -> e^+\nu(\gamma) decay branching ratio, at the Paul Scherrer Institute, to reduce the present 40\times experimental precision lag behind theory to ~ 6-7\times. Because of large helicity suppression, R^\pi_{e/\mu} is uniquely sensitive to contributions from non-(V-A) physics, making this decay a particularly suitable subject of study. Even at current precision, the experimental value of B_{\pi e2} provides the most accurate test of lepton universality available. During runs in 2008-10, PEN has accumulated over 2\times 10^7 \pi_{e2} events; a comprehensive maximum-likelihood analysis is currently under way. The new data will also lead to improved precision of the earlier PIBETA results on radiative \pi and \mu decays.

    Comment: 3 pages, 3 figures, to appear in Proceedings, 11th Conference on the Intersections of Particle and Nuclear Physics (CIPANP 2012), held at St. Petersburg, Florida, 29 May - 3 June 2012
    Keywords High Energy Physics - Experiment ; Nuclear Experiment
    Subject code 612
    Publishing date 2012-10-18
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Measurement of the Positive Muon Anomalous Magnetic Moment to 0.46 ppm.

    Abi, B / Albahri, T / Al-Kilani, S / Allspach, D / Alonzi, L P / Anastasi, A / Anisenkov, A / Azfar, F / Badgley, K / Baeßler, S / Bailey, I / Baranov, V A / Barlas-Yucel, E / Barrett, T / Barzi, E / Basti, A / Bedeschi, F / Behnke, A / Berz, M /
    Bhattacharya, M / Binney, H P / Bjorkquist, R / Bloom, P / Bono, J / Bottalico, E / Bowcock, T / Boyden, D / Cantatore, G / Carey, R M / Carroll, J / Casey, B C K / Cauz, D / Ceravolo, S / Chakraborty, R / Chang, S P / Chapelain, A / Chappa, S / Charity, S / Chislett, R / Choi, J / Chu, Z / Chupp, T E / Convery, M E / Conway, A / Corradi, G / Corrodi, S / Cotrozzi, L / Crnkovic, J D / Dabagov, S / De Lurgio, P M / Debevec, P T / Di Falco, S / Di Meo, P / Di Sciascio, G / Di Stefano, R / Drendel, B / Driutti, A / Duginov, V N / Eads, M / Eggert, N / Epps, A / Esquivel, J / Farooq, M / Fatemi, R / Ferrari, C / Fertl, M / Fiedler, A / Fienberg, A T / Fioretti, A / Flay, D / Foster, S B / Friedsam, H / Frlež, E / Froemming, N S / Fry, J / Fu, C / Gabbanini, C / Galati, M D / Ganguly, S / Garcia, A / Gastler, D E / George, J / Gibbons, L K / Gioiosa, A / Giovanetti, K L / Girotti, P / Gohn, W / Gorringe, T / Grange, J / Grant, S / Gray, F / Haciomeroglu, S / Hahn, D / Halewood-Leagas, T / Hampai, D / Han, F / Hazen, E / Hempstead, J / Henry, S / Herrod, A T / Hertzog, D W / Hesketh, G / Hibbert, A / Hodge, Z / Holzbauer, J L / Hong, K W / Hong, R / Iacovacci, M / Incagli, M / Johnstone, C / Johnstone, J A / Kammel, P / Kargiantoulakis, M / Karuza, M / Kaspar, J / Kawall, D / Kelton, L / Keshavarzi, A / Kessler, D / Khaw, K S / Khechadoorian, Z / Khomutov, N V / Kiburg, B / Kiburg, M / Kim, O / Kim, S C / Kim, Y I / King, B / Kinnaird, N / Korostelev, M / Kourbanis, I / Kraegeloh, E / Krylov, V A / Kuchibhotla, A / Kuchinskiy, N A / Labe, K R / LaBounty, J / Lancaster, M / Lee, M J / Lee, S / Leo, S / Li, B / Li, D / Li, L / Logashenko, I / Lorente Campos, A / Lucà, A / Lukicov, G / Luo, G / Lusiani, A / Lyon, A L / MacCoy, B / Madrak, R / Makino, K / Marignetti, F / Mastroianni, S / Maxfield, S / McEvoy, M / Merritt, W / Mikhailichenko, A A / Miller, J P / Miozzi, S / Morgan, J P / Morse, W M / Mott, J / Motuk, E / Nath, A / Newton, D / Nguyen, H / Oberling, M / Osofsky, R / Ostiguy, J-F / Park, S / Pauletta, G / Piacentino, G M / Pilato, R N / Pitts, K T / Plaster, B / Počanić, D / Pohlman, N / Polly, C C / Popovic, M / Price, J / Quinn, B / Raha, N / Ramachandran, S / Ramberg, E / Rider, N T / Ritchie, J L / Roberts, B L / Rubin, D L / Santi, L / Sathyan, D / Schellman, H / Schlesier, C / Schreckenberger, A / Semertzidis, Y K / Shatunov, Y M / Shemyakin, D / Shenk, M / Sim, D / Smith, M W / Smith, A / Soha, A K / Sorbara, M / Stöckinger, D / Stapleton, J / Still, D / Stoughton, C / Stratakis, D / Strohman, C / Stuttard, T / Swanson, H E / Sweetmore, G / Sweigart, D A / Syphers, M J / Tarazona, D A / Teubner, T / Tewsley-Booth, A E / Thomson, K / Tishchenko, V / Tran, N H / Turner, W / Valetov, E / Vasilkova, D / Venanzoni, G / Volnykh, V P / Walton, T / Warren, M / Weisskopf, A / Welty-Rieger, L / Whitley, M / Winter, P / Wolski, A / Wormald, M / Wu, W / Yoshikawa, C

    Physical review letters

    2021  Volume 126, Issue 14, Page(s) 141801

    Abstract: We present the first results of the Fermilab National Accelerator Laboratory (FNAL) Muon g-2 Experiment for the positive muon magnetic anomaly a_{μ}≡(g_{μ}-2)/2. The anomaly is determined from the precision measurements of two angular frequencies. ... ...

    Abstract We present the first results of the Fermilab National Accelerator Laboratory (FNAL) Muon g-2 Experiment for the positive muon magnetic anomaly a_{μ}≡(g_{μ}-2)/2. The anomaly is determined from the precision measurements of two angular frequencies. Intensity variation of high-energy positrons from muon decays directly encodes the difference frequency ω_{a} between the spin-precession and cyclotron frequencies for polarized muons in a magnetic storage ring. The storage ring magnetic field is measured using nuclear magnetic resonance probes calibrated in terms of the equivalent proton spin precession frequency ω[over ˜]_{p}^{'} in a spherical water sample at 34.7 °C. The ratio ω_{a}/ω[over ˜]_{p}^{'}, together with known fundamental constants, determines a_{μ}(FNAL)=116 592 040(54)×10^{-11} (0.46 ppm). The result is 3.3 standard deviations greater than the standard model prediction and is in excellent agreement with the previous Brookhaven National Laboratory (BNL) E821 measurement. After combination with previous measurements of both μ^{+} and μ^{-}, the new experimental average of a_{μ}(Exp)=116 592 061(41)×10^{-11} (0.35 ppm) increases the tension between experiment and theory to 4.2 standard deviations.
    Language English
    Publishing date 2021-04-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.126.141801
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    In stock of ZB MED Bonn / Germany

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