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  1. Article ; Online: The Feasibility of Breast-Conserving Surgery for Multiple Ipsilateral Breast Cancer: An Initial Report from the ACOSOG Z11102 (Alliance) Trial: A Comment.

    Alser, Osaid

    Annals of surgical oncology

    2023  Volume 30, Issue 6, Page(s) 3281

    MeSH term(s) Humans ; Female ; Breast Neoplasms/surgery ; Mastectomy, Segmental ; Feasibility Studies ; Breast ; Neoplasm Recurrence, Local/surgery
    Language English
    Publishing date 2023-04-01
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-023-13373-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Urgent call for protecting health-care workers in Palestine.

    Alser, Osaid / Alser, Muath

    Lancet (London, England)

    2023  Volume 402, Issue 10414, Page(s) 1746–1747

    Language English
    Publishing date 2023-10-31
    Publishing country England
    Document type Letter
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(23)02404-2
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  3. Article ; Online: Inclusivity at surgical meetings: Can we do better through food?

    Mansour, Rania / Alser, Osaid

    American journal of surgery

    2023  Volume 230, Page(s) 108–110

    MeSH term(s) Humans ; Food
    Language English
    Publishing date 2023-11-28
    Publishing country United States
    Document type Editorial
    ZDB-ID 2953-1
    ISSN 1879-1883 ; 0002-9610
    ISSN (online) 1879-1883
    ISSN 0002-9610
    DOI 10.1016/j.amjsurg.2023.11.029
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  4. Article ; Online: Morphine for Gaza? Limits of care during genocidal violence.

    Coghlan, Rachel / Smith, James / Alser, Osaid

    Lancet (London, England)

    2024  Volume 403, Issue 10424, Page(s) 350–351

    MeSH term(s) Humans ; Morphine ; Violence/prevention & control ; Genocide
    Chemical Substances Morphine (76I7G6D29C)
    Language English
    Publishing date 2024-01-16
    Publishing country England
    Document type Letter
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(24)00014-X
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  5. Article ; Online: Health Care Workers and War in the Middle East.

    Alser, Osaid / Gilbert, Mads / Loubani, Tarek

    JAMA

    2023  Volume 331, Issue 1, Page(s) 77

    MeSH term(s) Humans ; Health Personnel ; Middle East ; Warfare
    Language English
    Publishing date 2023-12-04
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0254-9077 ; 0002-9955 ; 0098-7484
    DOI 10.1001/jama.2023.26407
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  6. Article: Treatment Options for Dupuytren's Disease: Tips and Tricks.

    Denkler, Keith A / Park, Keon Min / Alser, Osaid

    Plastic and reconstructive surgery. Global open

    2022  Volume 10, Issue 1, Page(s) e4046

    Abstract: Dupuytren's disease (DD) is a common fibroproliferative condition of the hand.: Methods: Management of DD includes observation, non-operative management, and operative management. Operative treatments include percutaneous needle fasciotomy (PNF), open ...

    Abstract Dupuytren's disease (DD) is a common fibroproliferative condition of the hand.
    Methods: Management of DD includes observation, non-operative management, and operative management. Operative treatments include percutaneous needle fasciotomy (PNF), open fasciotomy (OF), Clostridium collagenase histolyticum (CCH) injections, limited fasciectomy (LF) and dermofasciectomy (DF). The various methods of DD treatment are reviewed.
    Results: We summarize the highlights of each treatment option as well as the strengths and weaknesses. PNF has an immediate improvement, but a higher recurrence rate, potential problematic skin tears, and rare tendon or nerve complications. Limited fasciectomy removes the thickened, diseased tissue but has a more prolonged recovery and has a higher rate of significant complications. Dermofasciectomy has the highest complication rate, and the lowest recurrence. Also, secondary fasciectomy after a previous dermofasciectomy has an unexpected amputation rate as high as 8%. Collagenase injections require two visits, have an increased number of minor side effects such as skin tears, and have rare but significant side effects such as tendon rupture.
    Conclusions: This article gives an overview of different treatment options for DD and each of their strengths and weaknesses and provides procedural tips.
    Language English
    Publishing date 2022-01-27
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2851682-5
    ISSN 2169-7574 ; 2169-7574
    ISSN (online) 2169-7574
    ISSN 2169-7574
    DOI 10.1097/GOX.0000000000004046
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 7091: Show issues Location:
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  7. Article ; Online: Indications and Outcomes of Completion Cholecystectomy: A 5-year Experience From a Rural Tertiary Center.

    Alser, Osaid / Dissanaike, Sharmila / Shrestha, Kripa / Alghoul, Heba / Onkendi, Edwin

    The American surgeon

    2022  Volume 89, Issue 11, Page(s) 4584–4589

    Abstract: Background: Completion cholecystectomy (CC) is performed for recurrent or persistent biliary symptoms following subtotal cholecystectomy (STC) or incomplete cholecystectomy (IC). Due to its complexity, cases are often referred to hepato-pancreato- ... ...

    Abstract Background: Completion cholecystectomy (CC) is performed for recurrent or persistent biliary symptoms following subtotal cholecystectomy (STC) or incomplete cholecystectomy (IC). Due to its complexity, cases are often referred to hepato-pancreato-biliary (HBP) surgeons. There is little published literature on indications or outcomes of CC.
    Methods: Completion cholecystectomy cases performed between 2016 and 2021 by the sole HPB surgeon covering a rural referral base of >250-mile radius in West Texas were included. Primary variables of interest include indications and outcomes of CC.
    Results: Of the eleven patients included, 5 (45.5%) had laparoscopic STC, 3 patients (27.3%) had laparoscopic converted to open STC, and 2 (18.2%) had laparoscopic IC. Most STC cases (6/9, 66.6%) were reconstituting, while 3 STC cases were fenestrating (all had persistent bile leak). For reconstituting STC, indications were symptomatic cholelithiasis in 5 patients (45.5%), and choledocholithiasis in 3 patients (27.3%). The median (IQR) duration between index procedure and subsequent CC was 15 (1.4-92) months. The median (IQR) remnant gallbladder length was 4 (3-4.5) cm. Completion cholecystectomy was performed robotically in 8 cases (72.7%). Post-CC complications occurred in 3 patients (27.3%); these were 1 superficial surgical site infection, 1 hepatic abscess requiring percutaneous drainage, and lastly atrial fibrillation.
    Conclusions: All patients requiring CC had residual gallbladder remnant >2.5 cm; this is longer than recommended for STC. Completion cholecystectomy is a complex operation that carries significant morbidity, even when performed using minimally invasive techniques. As bailout procedures become more common in severely inflamed cholecystitis, it is important to collate more data on the outcomes of requiring CC.
    MeSH term(s) Humans ; Treatment Outcome ; Cholecystectomy/methods ; Cholecystectomy, Laparoscopic/adverse effects ; Cholecystitis/surgery ; Choledocholithiasis/surgery
    Language English
    Publishing date 2022-08-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 202465-2
    ISSN 1555-9823 ; 0003-1348
    ISSN (online) 1555-9823
    ISSN 0003-1348
    DOI 10.1177/00031348221124331
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Palliative Reconstructive Surgery for Advanced Maxillofacial Osteosarcoma in the Peak of COVID-19 Pandemic: A Matter of Ethical Decision-making.

    Gasteratos, Konstantinos / Alser, Osaid / Hart, Justin / Chaiyasate, Kongkrit

    Plastic and reconstructive surgery. Global open

    2021  Volume 9, Issue 3, Page(s) e3545

    Abstract: The coronavirus disease 2019 posed an unprecedented strain to plastic surgery services. The scarcity of validated guidelines-at the beginning of this healthcare crisis-to direct clinical, ethical, transparent decision-making for head and neck cancer ... ...

    Abstract The coronavirus disease 2019 posed an unprecedented strain to plastic surgery services. The scarcity of validated guidelines-at the beginning of this healthcare crisis-to direct clinical, ethical, transparent decision-making for head and neck cancer patients requiring palliative reconstructive surgery was a difficult situation. We report a 15-year-old girl with an advanced chemoresistant rare radiotherapy-induced mandibular osteosarcoma during the early phase of the pandemic in the United States in mid-March 2020, when official recommendations for triage were still developing. Local guidelines suggested canceling all elective procedures, and allowed operating emergency and/or nonelective cases only. Many surgeons declined surgery due to patient's poor prognosis and high perioperative risk, but her mother pursued different professional opinions elsewhere. However, upon Beaumont hospital approval, the patient underwent radical en bloc resection of the tumor, hemimandibulectomy, zygomatic resection, maxillectomy, and hemipalate resection followed by reconstruction with free fibula osteocutaneous and anterolateral thigh flaps. The challenging decision to proceed with surgery was based on evidence-based and objective risk-stratifying scores, available at the time, and ethical recommendations from emerging reliable published literature. Despite a favorable postoperative outcome, the patient expired due to cardiac complications of the disease. Our patient taught us that ethical decision-making, sound clinical judgment, and a patient-centered individualized approach remain pivotal aspects of the medical profession. Although the surgery will not provide a cure for the disease, we have found that palliative reconstructive surgery can greatly improve patient's quality of life, and help family cope with the advancing stages of disease.
    Language English
    Publishing date 2021-03-29
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2851682-5
    ISSN 2169-7574 ; 2169-7574
    ISSN (online) 2169-7574
    ISSN 2169-7574
    DOI 10.1097/GOX.0000000000003545
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Rebuilding Global Plastic Surgery Services and Safeguarding Workforce Density after COVID-19.

    Kadhum, Murtaza / Alser, Osaid / Bandyopadhyay, Soham / Khundkar, Roba

    Plastic and reconstructive surgery

    2021  Volume 148, Issue 1, Page(s) 167e–168e

    MeSH term(s) COVID-19/mortality ; COVID-19/prevention & control ; COVID-19/transmission ; Global Burden of Disease ; Health Personnel/organization & administration ; Health Personnel/statistics & numerical data ; Health Services Accessibility/organization & administration ; Health Services Accessibility/statistics & numerical data ; Health Services Accessibility/trends ; Health Workforce/organization & administration ; Health Workforce/statistics & numerical data ; Humans ; Infectious Disease Transmission, Patient-to-Professional/prevention & control ; Infectious Disease Transmission, Patient-to-Professional/statistics & numerical data ; Pandemics/prevention & control ; Pandemics/statistics & numerical data ; Safety ; Surgery, Plastic/organization & administration ; Surgery, Plastic/statistics & numerical data ; Surgery, Plastic/trends
    Language English
    Publishing date 2021-06-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208012-6
    ISSN 1529-4242 ; 0032-1052 ; 0096-8501
    ISSN (online) 1529-4242
    ISSN 0032-1052 ; 0096-8501
    DOI 10.1097/PRS.0000000000008027
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The evidence behind the use of platelet-rich plasma (PRP) in scar management: a literature review.

    Alser, Osaid H / Goutos, Ioannis

    Scars, burns & healing

    2018  Volume 4, Page(s) 2059513118808773

    Abstract: Introduction: Autologous platelet-based concentrates represent increasingly popular adjuncts to a variety of medical, surgical and aesthetic interventions. Their beneficial potential rests on the ability to deliver a high concentration of growth factors ...

    Abstract Introduction: Autologous platelet-based concentrates represent increasingly popular adjuncts to a variety of medical, surgical and aesthetic interventions. Their beneficial potential rests on the ability to deliver a high concentration of growth factors to the target tissues. There are currently no reports in the literature appraising the evidence behind the use of platelet-rich plasma (PRP) in scar management.
    Methods: A detailed English literature review was conducted using PubMed Medline, Embase and Web of Science; the manuscripts were appraised and classified according to the Joanna Briggs Institute Levels of evidence. The results are presented in descending order of evidence separately for atrophic, keloid, surgical and traumatic scars.
    Discussion: On the basis of level 1 evidence currently available, it appears that PRP can improve the quality of atrophic acne scars treated with ablative fractional CO2 laser and decrease the duration of laser-related side effects including oedema and erythema. Regarding surgical scars, the current data suggest that PRP may improve wound healing and early scar quality; furthermore, incorporation of PRP in fat-grafting procedures undertaken in conjunction with non-ablative, fractional laser can contribute to better wound healing as well as a significant improvement in texture, colour and contour in traumatic scar resurfacing. There are no high level studies at present to support the incorporation of autologous platelet-based concentrates in the management of keloid scars.
    Conclusion: PRP is a promising adjunct in scar management practice. Further research with long-term follow-up is warranted to delineate the value of this modality in different subtypes of scars.
    Language English
    Publishing date 2018-11-18
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2837910-X
    ISSN 2059-5131 ; 2059-5131
    ISSN (online) 2059-5131
    ISSN 2059-5131
    DOI 10.1177/2059513118808773
    Database MEDical Literature Analysis and Retrieval System OnLINE

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