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Article: Using mass spectrometry imaging to visualize age-related subcellular disruption.

Hogan, Kelly A / Zeidler, Julianna D / Beasley, Heather K / Alsaadi, Abrar I / Alshaheeb, Abdulkareem A / Chang, Yi-Chin / Tian, Hua / Hinton, Antentor O / McReynolds, Melanie R

Frontiers in molecular biosciences

2023  Volume 10, Page(s) 906606

Abstract: Metabolic homeostasis balances the production and consumption of energetic molecules to maintain active, healthy cells. Cellular stress, which disrupts metabolism and leads to the loss of cellular homeostasis, is important in age-related diseases. We ... ...

Abstract Metabolic homeostasis balances the production and consumption of energetic molecules to maintain active, healthy cells. Cellular stress, which disrupts metabolism and leads to the loss of cellular homeostasis, is important in age-related diseases. We focus here on the role of organelle dysfunction in age-related diseases, including the roles of energy deficiencies, mitochondrial dysfunction, endoplasmic reticulum (ER) stress, changes in metabolic flux in aging (e.g., Ca
Language English
Publishing date 2023-03-08
Publishing country Switzerland
Document type Journal Article ; Review
ZDB-ID 2814330-9
ISSN 2296-889X
ISSN 2296-889X
DOI 10.3389/fmolb.2023.906606
Database MEDical Literature Analysis and Retrieval System OnLINE

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