Article ; Online: Exploring the untapped pharmacological potential of imidazopyridazines.
RSC advances
2024 Volume 14, Issue 6, Page(s) 3972–3984
Abstract: Imidazopyridazines are fused heterocycles, like purines, with a pyridazine ring replacing the pyrimidine ring in purines. Imidazopyridazines have been primarily studied for their kinase inhibition activity in the development of new anticancer and ... ...
| Abstract | Imidazopyridazines are fused heterocycles, like purines, with a pyridazine ring replacing the pyrimidine ring in purines. Imidazopyridazines have been primarily studied for their kinase inhibition activity in the development of new anticancer and antimalarial agents. In addition to this, they have also been investigated for their anticonvulsant, antiallergic, antihistamine, antiviral, and antitubercular properties. Herein, we review the background and development of different imidazopyridazines as potential pharmacological agents. Moreover, the scope of this relatively less charted heterocyclic scaffold is also highlighted. |
|---|---|
| Language | English |
| Publishing date | 2024-01-29 |
| Publishing country | England |
| Document type | Journal Article ; Review |
| ISSN | 2046-2069 |
| ISSN (online) | 2046-2069 |
| DOI | 10.1039/d3ra07280k |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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