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Article: Cardioprotective properties of Artemisia herba alba nanoparticles against heart attack in rats: A study of the antioxidant and hypolipidemic activities.

Alshehri, Mohammed Ali

2021 Volume 29, Issue 4, Page(s) 2336–2347

Abstract: Recently, pharmaceutical scientists' interest has increased to find novel pharmaceutical natural substances with potent antioxidant capacity and very low side effects to be used safely in preventive medicine. One of the most common types of diseases with ...

Abstract	Recently, pharmaceutical scientists' interest has increased to find novel pharmaceutical natural substances with potent antioxidant capacity and very low side effects to be used safely in preventive medicine. One of the most common types of diseases with a large spread globally is cardiovascular diseases, which cause a high rate of deaths annually. The present study evaluated the use of
Language	English
Publishing date	2021-12-13
Publishing country	Saudi Arabia
Document type	Journal Article
ZDB-ID	2515206-3
ISSN	2213-7106 ; 1319-562X
ISSN (online)	2213-7106
ISSN	1319-562X
DOI	10.1016/j.sjbs.2021.12.009
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Article: Evaluation of

Asiri, Saeed Ahmed / Shabnam, Madeeha / Zafar, Rehman / Alshehri, Osama M / Alshehri, Mohammed Ali / Sadiq, Abdul / Mahnashi, Mater H / Jan, Muhammad Saeed

Frontiers in chemistry

2024 Volume 12, Page(s) 1351827

Abstract: Habenaria ... ...

Abstract	Habenaria aitchisonii
Language	English
Publishing date	2024-03-19
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2711776-5
ISSN	2296-2646
ISSN	2296-2646
DOI	10.3389/fchem.2024.1351827
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Article ; Online: Larvicidal potential of Cipadessa baccifera leaf extract-synthesized zinc nanoparticles against three major mosquito vectors

Ramkumar Govindaraju / Shivakumar Muthugoundar Subramanian / Alshehri Mohammed Ali / Panneerselvam Chellasamy / Sayed Samy

Green Processing and Synthesis, Vol 11, Iss 1, Pp 757-

2022 Volume 765

Abstract: Mosquitoes are important vectors, which transmit many communicable diseases throughout the world. Synthetic insecticides, such as organophosphate and pyrethroids, are commonly used for their control in the vector control program. Insecticidal compounds ... ...

Abstract	Mosquitoes are important vectors, which transmit many communicable diseases throughout the world. Synthetic insecticides, such as organophosphate and pyrethroids, are commonly used for their control in the vector control program. Insecticidal compounds from natural sources, notably from plants and synthesized nanoparticles (NPs) are promising tools for managing such vectors. Hence, the study aimed to analyze the insecticidal potentiality of leaf extract of Cipadessa baccifera and synthesized ZnNPs against three major mosquito vectors. The results recorded from UV-Vis spectroscopy show the peak absorption spectrum at 420 nm. In FTIR, the maximum peak value is 562.85 cm−1 assigned to the N–H group (amide group). The EDAX analysis shows a peak around 63.29, which confirms the binding intensity of selenium. In the scanning electron microscopy analysis, the synthesized ZnNPs sizes were ranging from 49.21 to 65.43 nm. The synthesized ZnNPs produced high mortality against Culex quinquefasciatus LC50 = 0.049653 mg·mL−1; LC90 = 0.9842 mg·mL−1), Anopheles stephensi (LC50 = 0.053421 mg·mL−1 and LC90 = 0.027761 mg·mL−1), and Aedes aegypti LC50 = 0.55214 mg·mL−1 and LC90 = 0.7456 mg·mL−1). These results suggest that the C. baccifera leaf extract-mediated biosynthesis of ZnNPs has the potential to be used as an ideal eco-friendly approach toward the control of mosquito vectors at early stages.
Keywords	botanical extracts ; bionanopesticides ; cipadessa baccifera ; vector control ; Chemistry ; QD1-999
Subject code	540
Language	English
Publishing date	2022-08-01T00:00:00Z
Publisher	De Gruyter
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Efficacy of chitosan silver nanoparticles from shrimp-shell wastes against major mosquito vectors of public health importance

Alshehri Mohammed Ali / Aziz Al Thabiani / Trivedi Subrata / Panneerselvam Chellasamy

Green Processing and Synthesis, Vol 9, Iss 1, Pp 675-

2020 Volume 684

Abstract: Mosquito-borne diseases are causing serious damage to public health worldwide, and control of these deadly mosquito vectors is a major thrust area for epidemiologists and public health workers. Therefore, the present research reports an eco-friendly ... ...

Abstract	Mosquito-borne diseases are causing serious damage to public health worldwide, and control of these deadly mosquito vectors is a major thrust area for epidemiologists and public health workers. Therefore, the present research reports an eco-friendly solution with multipotency of silver nanoparticle fabricated from shrimp shell biowaste in controlling mosquitoes and bacterial pathogens. The biofabricated chitosan silver nanoparticles (Cs-AgNPs) were confirmed by UV-visible spectroscopy, transmission electron microscopy (TEM), Fourier transform infrared spectroscopy, energy dispersive X-ray spectroscopy, X-ray powder diffraction and zeta potential analysis. The TEM studies showed that the obtained Cs-AgNPs were mostly spherical in shape. Low doses of chitosan and Cs-AgNPs showed high mosquitocidal properties against both larvae and adult of Anopheles stephensi, Aedes aegypti, and Culex quinquefasciatus. The LC50 (lethal concentration 50%) of Cs-AgNPs was 10.240 ppm (fourth instar larvae) and 9.671 ppm (adult) for An. stephensi; 11.349 ppm (fourth instar) and 12.015 ppm (adult) for Ae. aegypti and 12.426 ppm (fourth instar) and 12.965 ppm (adult) for Cx. quinquefasciatus. The concerning part of antibacterial studies showed that Cs-AgNP had significant inhibition on tested bacterial pathogens. Overall, this study shows that chitosan extracted from the shrimp shell wastes can be used as a potential source for controlling major mosquito vectors.
Keywords	shrimp shells ; larvicidal ; adulticidal ; green synthesis ; antibacterial activity ; Chemistry ; QD1-999
Language	English
Publishing date	2020-11-01T00:00:00Z
Publisher	De Gruyter
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: An unusual case of gastric angiolipoma presenting with upper gastrointestinal bleeding.

Alghamdi, Saeed Abdulrahman / Alshammery, Sahar Matter / Alamari, Mahammad Saeed / Alshehri, Mohammed Ali / Alshahrani, Amer Saeed

Oxford medical case reports

2022 Volume 2022, Issue 11, Page(s) omac119

Abstract: Gastric angiolipomas (GA) are rare benign tumors that can present with gastrointestinal bleeding and anemia. We describe a 73-year-old woman who presented with a 3-day history of fatiguability, epigastric pain and melena. A computed tomography scan ... ...

Abstract	Gastric angiolipomas (GA) are rare benign tumors that can present with gastrointestinal bleeding and anemia. We describe a 73-year-old woman who presented with a 3-day history of fatiguability, epigastric pain and melena. A computed tomography scan revealed a hypodense lesion, measuring 6 × 6 × 5 cm, along the upper part of the stomach. An upper endoscopy revealed a large polypoid lesion, measuring 8 × 6 cm, between the cardia and body of the stomach. Multiple biopsy specimens were taken, and a histopathological examination showed an acute erosive helicobacter-associated reactive gastritis but no definitive atypia. A linear endoscopic ultrasound revealed a large, homogenous, hyperechoic lesion, consistent with a lipoma, in the body of the stomach. A fine needle aspiration was negative for malignancy. A laparoscopy was offered, and a wedge resection was performed. A histopathological examination revealed a well-circumscribed, encapsulated lipomatous tumor in the gastric submucosa with focal mucosal ulceration. The patient had an uneventful postoperative recovery and her hemoglobin level subsequently returned to normal. Overall, clinicians may be unfamiliar with GA because patients may present with signs and symptoms that can be confused with other gastrointestinal conditions. Physicians should be aware of the characteristic histopathological features to distinguish GA from other diseases of the gastrointestinal tract that may share similar clinical or radiologic features.
Language	English
Publishing date	2022-11-24
Publishing country	England
Document type	Case Reports
ZDB-ID	2766251-2
ISSN	2053-8855
ISSN	2053-8855
DOI	10.1093/omcr/omac119
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Article ; Online: Green synthesis of ZnO-NPs using endophytic fungal extract of

Nehru, Lavanya / Kandasamy, Gayathri Devi / Sekar, Vanaraj / Alshehri, Mohammed Ali / Panneerselvam, Chellasamy / Alasmari, Abdulrahman / Kathirvel, Preethi

Artificial cells, nanomedicine, and biotechnology

2023 Volume 51, Issue 1, Page(s) 318–333

Abstract: The biogenic manufacture of nanoparticles utilising endophytic fungus is an eco-friendly, cost-effective, and secure alternative to constructing chemical methods. The prime focus of the study was to fabricate ZnONPs using the biomass filtrate of ... ...

Abstract	The biogenic manufacture of nanoparticles utilising endophytic fungus is an eco-friendly, cost-effective, and secure alternative to constructing chemical methods. The prime focus of the study was to fabricate ZnONPs using the biomass filtrate of endophytic
MeSH term(s)	Zinc Oxide/pharmacology ; Antioxidants ; Ascomycota ; Asteraceae ; Plant Extracts/pharmacology
Chemical Substances	Zinc Oxide (SOI2LOH54Z) ; Antioxidants ; Plant Extracts
Language	English
Publishing date	2023-07-01
Publishing country	England
Document type	Journal Article
ZDB-ID	2723095-8
ISSN	2169-141X ; 2169-1401
ISSN (online)	2169-141X
ISSN	2169-1401
DOI	10.1080/21691401.2023.2232654
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Article ; Online: TiO

Subramanian, Rajaduraipandian / Ponnanikajamideen, Mohemedibrahim / Samuel Rajendran, Rapael / Alshehri, Mohammed Ali / Alasmari, Abdulrahman / Panneerselvam, Chellasamy / Periyasamy, Selvendiran

Drug and chemical toxicology

2023 Volume 47, Issue 1, Page(s) 90–100

Abstract: The present study was designed to green synthesize titanium dioxide nanoparticles (G- ... ...

Abstract	The present study was designed to green synthesize titanium dioxide nanoparticles (G-TiO
MeSH term(s)	Animals ; Zebrafish ; Metal Nanoparticles/toxicity ; Nanoparticles ; Anti-Infective Agents ; Anti-Bacterial Agents/toxicity ; Titanium/toxicity ; Hypoglycemic Agents ; Anti-Inflammatory Agents
Chemical Substances	Anti-Infective Agents ; Anti-Bacterial Agents ; Titanium (D1JT611TNE) ; Hypoglycemic Agents ; Anti-Inflammatory Agents
Language	English
Publishing date	2023-06-14
Publishing country	United States
Document type	Journal Article
ZDB-ID	548368-2
ISSN	1525-6014 ; 0148-0545
ISSN (online)	1525-6014
ISSN	0148-0545
DOI	10.1080/01480545.2023.2217697
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Zs.A 1380: Show issues

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Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Anticancer, anti-proliferative activity of

Albinhassan, Tahani H / Saleh, Kamel A / Barhoumi, Zouhaier / Alshehri, Mohammed Ali / Al-Ghazzawi, Adel M

Journal of cancer research and therapeutics

2021 Volume 17, Issue 4, Page(s) 879–886

Abstract: Purpose: Medical halophytes plants are potent sources of bioactive secondary metabolite components used against different diseases. Avicenniamarina one of the typical halophytes plant species used in folk medicine to treat smallpox, rheumatism, and ... ...

Abstract	Purpose: Medical halophytes plants are potent sources of bioactive secondary metabolite components used against different diseases. Avicenniamarina one of the typical halophytes plant species used in folk medicine to treat smallpox, rheumatism, and ulcer. Despite the richness of A.marina with polyphenolic, flavonoids, terpenoid, and terpene, contents remain poorly investigated against cancer types. Consequently, to explore the function-composition relationship of A.marina hexane leaves crude extract, the current study designed to investigate the cytotoxicity, apoptotic and antiproliferative impacts on the colon (HCT-116), liver (HepG2), and breast (MCF-7) cancer cell lines. Materials and methods: Therefore, the cytotoxicity impact screening carried out by Sulforhodamine-B assay. While, the initiation of the apoptosis evaluated by chromatin condensing, early apoptosis, late apoptosis and the formation and appearance of apoptotic bodies. On the other hand, the flow cytometry used to identify the phase of inhibition where the determined IC Results: Revealed that hexane extract showed a weak induction of apoptosis despite the formation of apoptotic bodies and the high cell inhibitory effect on all tested cell lines with IC Conclusion: In the light of these results, the current study suggests that A.marina leaves hexane extract may be considered as a candidate for further anticancer drug development investigations.
MeSH term(s)	Apoptosis ; Avicennia/chemistry ; Cell Cycle ; Cell Proliferation ; HCT116 Cells ; Hep G2 Cells ; Humans ; MCF-7 Cells ; Neoplasms/drug therapy ; Neoplasms/pathology ; Plant Extracts/pharmacology ; Plant Leaves/chemistry
Chemical Substances	Plant Extracts
Language	English
Publishing date	2021-09-08
Publishing country	India
Document type	Journal Article
ZDB-ID	2187633-2
ISSN	1998-4138 ; 0973-1482
ISSN (online)	1998-4138
ISSN	0973-1482
DOI	10.4103/jcrt.JCRT_659_19
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Article: Inhibition of HDACs Suppresses Cell Proliferation and Cell Migration of Gastric Cancer by Regulating E2F5 Targeting BCL2.

Ali, Arshad / Ali, Ayaz / Khan, Shaker / Ibrahim, Muhammad / Alshehri, Mohammed Ali / Thirupathi, Anand

Life (Basel, Switzerland)

2021 Volume 11, Issue 12

Abstract: 1) Background: Gastric cancer (GC) is the most common high death-rate cancer type worldwide, with an enhanced prevalence and increased rate of mortality. Although significant evidence on surgery strategy has been generated for the treatment of GC, ... ...

Abstract	(1) Background: Gastric cancer (GC) is the most common high death-rate cancer type worldwide, with an enhanced prevalence and increased rate of mortality. Although significant evidence on surgery strategy has been generated for the treatment of GC, conclusions are still uncertain regarding profound metastatic or persevering gastric cancer. Therefore, it is essential to develop novel and effective biomarkers or therapeutic targets for the diagnosis of GC. Histone deacetylations (HDACs) are important epigenetic regulators that control the aberrant transcription of critical genes that are mainly involved in cell proliferation, cell migration, regulation of the cell cycle, and different signal pathways. (2) Methods: Expression analysis of HDACs family members and E2F5 in gastric cancer cell lines was determined by RT-PCR and Western blotting. The cell proliferation was determined through an MTT assay. Cell migration was determined using a wound-healing assay. Flow cytometry experiments were used to determine cell-cycle analysis. The statistical software OriginPro 2015 (OriginLab, Northampton, MA, USA) was used to analyze data. A
Language	English
Publishing date	2021-12-17
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662250-6
ISSN	2075-1729
ISSN	2075-1729
DOI	10.3390/life11121425
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Article ; Online: Ameliorated antimicrobial, antioxidant, and anticancer properties by Plectranthus vettiveroides root extract-mediated green synthesis of chitosan nanoparticles

Venkatesan Kamalesh Balakumar / Alamelu Saravanan / Priya Sivamathi Rathna / Jayaseelan Nivedha / Kamaraj Sathish-Kumar / Srinivasan Manoj Kumar / Alshehri Mohammed Ali / Panneerselvam Chellasamy / Saif Ahmed / Periyasamy Selvendiran

Green Processing and Synthesis, Vol 12, Iss 1, Pp 61-

2023 Volume 9

Keywords	antibacterial ; anticancer ; antioxidant ; chitosan nanoparticles ; plectranthus vettiveroides ; Chemistry ; QD1-999
Language	English
Publishing date	2023-10-01T00:00:00Z
Publisher	De Gruyter
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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