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  1. Article ; Online: Impact of booster vaccination on the control of COVID-19 Delta wave in the context of waning immunity: application to France in the winter 2021/22.

    Bosetti, Paolo / Tran Kiem, Cécile / Andronico, Alessio / Paireau, Juliette / Levy-Bruhl, Daniel / Alter, Lise / Fontanet, Arnaud / Cauchemez, Simon

    Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

    2022  Volume 27, Issue 1

    Abstract: Europe has experienced a large COVID-19 wave caused by the Delta variant in winter 2021/22. Using mathematical models applied to Metropolitan France, we find that boosters administered to ≥ 65, ≥ 50 or ≥ 18 year-olds may reduce the hospitalisation peak ... ...

    Abstract Europe has experienced a large COVID-19 wave caused by the Delta variant in winter 2021/22. Using mathematical models applied to Metropolitan France, we find that boosters administered to ≥ 65, ≥ 50 or ≥ 18 year-olds may reduce the hospitalisation peak by 25%, 36% and 43% respectively, with a delay of 5 months between second and third dose. A 10% reduction in transmission rates might further reduce it by 41%, indicating that even small increases in protective behaviours may be critical to mitigate the wave.
    MeSH term(s) COVID-19/prevention & control ; COVID-19 Vaccines/administration & dosage ; France/epidemiology ; Humans ; Immunization, Secondary ; SARS-CoV-2 ; Seasons ; Vaccination
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2022-01-06
    Publishing country Sweden
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1338803-4
    ISSN 1560-7917 ; 1025-496X
    ISSN (online) 1560-7917
    ISSN 1025-496X
    DOI 10.2807/1560-7917.ES.2022.27.1.2101125
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Rapid access to innovative medicinal products while ensuring relevant health technology assessment. Position of the French National Authority for Health.

    Vanier, Antoine / Fernandez, Judith / Kelley, Sophie / Alter, Lise / Semenzato, Patrick / Alberti, Corinne / Chevret, Sylvie / Costagliola, Dominique / Cucherat, Michel / Falissard, Bruno / Gueyffier, François / Lambert, Jérôme / Lengliné, Etienne / Locher, Clara / Naudet, Florian / Porcher, Raphael / Thiébaut, Rodolphe / Vray, Muriel / Zohar, Sarah /
    Cochat, Pierre / Le Guludec, Dominique

    BMJ evidence-based medicine

    2024  Volume 29, Issue 1, Page(s) 1–5

    MeSH term(s) Humans ; Technology Assessment, Biomedical ; Drug Industry
    Language English
    Publishing date 2024-01-19
    Publishing country England
    Document type Journal Article
    ISSN 2515-4478
    ISSN (online) 2515-4478
    DOI 10.1136/bmjebm-2022-112091
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Benefits and risks associated with different uses of the COVID-19 vaccine Vaxzevria: a modelling study, France, May to September 2021.

    Tran Kiem, Cécile / Andronico, Alessio / Bosetti, Paolo / Paireau, Juliette / Alter, Lise / Boëlle, Pierre-Yves / Fontanet, Arnaud / Lévy-Bruhl, Daniel / Cauchemez, Simon

    Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

    2021  Volume 26, Issue 26

    Abstract: Thrombosis with thrombocytopenia (TTS) has been identified as a rare adverse event following COVID-19 vaccination with Vaxzevria. We modelled the benefits and risks of Vaxzevria distribution from May to September 2021 in metropolitan France where other ... ...

    Abstract Thrombosis with thrombocytopenia (TTS) has been identified as a rare adverse event following COVID-19 vaccination with Vaxzevria. We modelled the benefits and risks of Vaxzevria distribution from May to September 2021 in metropolitan France where other vaccines are available, considering French hospitalisation data and European data on TTS. Across different scenarios, benefits of Vaxzevria distribution in people 55 years and older exceeded the risk of death from COVID-19. In young adults, risks were at least of similar magnitude as benefits.
    MeSH term(s) COVID-19 ; COVID-19 Vaccines ; France/epidemiology ; Humans ; Risk Assessment ; SARS-CoV-2 ; Young Adult
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2021-07-01
    Publishing country Sweden
    Document type Journal Article
    ZDB-ID 1338803-4
    ISSN 1560-7917 ; 1025-496X
    ISSN (online) 1560-7917
    ISSN 1025-496X
    DOI 10.2807/1560-7917.ES.2021.26.26.2100533
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Place of patient-reported outcomes & experiences measurements (PROMS/PREMS) in the assessment and pricing of Health technologies in France.

    Roussel, Christophe / Chassany, Olivier / Durand-Zaleski, Isabelle / Josseran, Anne / Alter, Lise / Auquier, Pascal / Bourguignon, Sandrine / Cachoux, Joude / Desforges, Claire / Fernandez, Judith / Gaudin, Anne-Françoise / Germe, Anne-Françoise / Haenel, Estelle / Olivier, Patrick / Maillard, Nicolas / Naïditch, Nicolas / Nguyen, Thao / Péan, Clarisse / Rumeau-Pichon, Catherine /
    Sales, Jean-Patrick / Schmidely, Nathalie / Tuppin, Philippe / Vray, Muriel

    Therapie

    2022  Volume 77, Issue 1, Page(s) 103–115

    Abstract: In the context of health technologies assessment, patient-reported outcome measures (PROMs) have become assessment criteria that are expected by evaluation agencies along with the other usual clinical criteria. PROMs instruments measure all aspects of ... ...

    Abstract In the context of health technologies assessment, patient-reported outcome measures (PROMs) have become assessment criteria that are expected by evaluation agencies along with the other usual clinical criteria. PROMs instruments measure all aspects of patient experience in connection with their health: symptoms, activities of daily living (physical function, sleep, etc.), various aspects of health-related quality of life (QoL), compliance, global impression of change in wellbeing. PROMs are useful both as 1) a primary or secondary efficacy endpoints, and 2) a tolerability criterion to supplement vigilance data reported by clinicians. Measurement of PROMs must be subject to methodological rigor that is identical to that of other assessment criteria measured by an observer. Scales must be validated, suitable for the objective, and where possible specific to a disease. In addition to standard measures of quality of life, PROMs are taken into consideration in the assessments performed by the HAS, even if their impact on the conclusions is difficult to isolate, as assessments are multifactorial and take into account all data available with regard to the medical context. The CEPS will indirectly take into account PROMs in the fixing of the price or tariff only if they have contributed to the award of the ASA/ASMR by the ad hoc committee of the HAS. The working group has formulated three recommendations which aim to further the implementation of patient-reported outcome measures: (1) Better information for all parties involved in a dossier for technology assessment, (2) Systematization of the collection of PROMs for evaluation of health products, (3) Improved quality of dossiers thanks to the use of relevant and validated tools.
    MeSH term(s) Activities of Daily Living ; Costs and Cost Analysis ; France ; Humans ; Patient Reported Outcome Measures ; Quality of Life
    Language English
    Publishing date 2022-01-31
    Publishing country France
    Document type Journal Article
    ZDB-ID 603474-3
    ISSN 1958-5578 ; 0040-5957
    ISSN (online) 1958-5578
    ISSN 0040-5957
    DOI 10.1016/j.therap.2022.01.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: [No title information]

    Roussel, Christophe / Chassany, Olivier / Durand-Zaleski, Isabelle / Josseran, Anne / Alter, Lise / Auquier, Pascal / Bourguignon, Sandrine / Cachoux, Joude / Desforges, Claire / Fernandez, Judith / Gaudin, Anne-Françoise / Germe, Anne-Françoise / Haenel, Estelle / Olivier, Patrick / Maillard, Nicolas / Naïditch, Nicolas / Nguyen, Thao / Péan, Clarisse / Rumeau-Pichon, Catherine /
    Sales, Jean-Patrick / Schmidely, Nathalie / Tuppin, Philippe / Vray, Muriel

    Therapie

    2022  Volume 77, Issue 1, Page(s) 89–102

    Title translation Place des mesures rapportées par les patients (PROMS/PREMS) dans l’évaluation et la valorisation des technologies de santé en France.
    MeSH term(s) Biomedical Technology ; France ; Health Promotion ; Humans ; Quality of Life
    Language French
    Publishing date 2022-01-13
    Publishing country France
    Document type Journal Article
    ZDB-ID 603474-3
    ISSN 1958-5578 ; 0040-5957
    ISSN (online) 1958-5578
    ISSN 0040-5957
    DOI 10.1016/j.therap.2022.01.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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