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  1. Article ; Online: Effect of potential microplastics in sewage effluent on Nile Tilapia and photocatalytic remediation with zinc oxide nanoparticles.

    Alanazi, Manal Qayyadh / Virk, Promy / Alterary, Seham Soliman / Awad, Manal / Ahmad, Zubair / Albadri, Abdulrehman M / Ortashi, KalidM / Ahmed, Mohieldeen Mahgoub A / Ali Yousef, Mohamed Ismail / Elobeid, Mai / Al-Qahtani, Ebtesam Abdullah

    Environmental pollution (Barking, Essex : 1987)

    2023  Volume 332, Page(s) 121946

    Abstract: The aim of the present study was a qualitative assessment of potential microplastics (MPs) in the sewage effluent collected from a local sewage treatment plant located in Riyadh City, Saudi Arabia. The composite samples of domestic sewage effluent were ... ...

    Abstract The aim of the present study was a qualitative assessment of potential microplastics (MPs) in the sewage effluent collected from a local sewage treatment plant located in Riyadh City, Saudi Arabia. The composite samples of domestic sewage effluent were subjected to UV (ultraviolet) light-induced zinc oxide nanoparticles (ZnONPs) mediated photocatalysis. The first phase of the study included the synthesis of the ZnONPs with an extensive characterization. The synthesized nanoparticles were 220 nm in size with a characteristic spherical/hexagonal shape. These NPs were then used at three different concentrations (10 mM, 20 mM, and 30 mM) for the UV light-induced photocatalysis. A shift in the Raman spectra on photodegradation mirrored the surface changes of the functional groups shown by the FTIR spectra; presence of functional groups containing oxygen and C-C bonds associated with oxidation and chain scission. SEM micrographs showed photodegraded particles. Complementary elemental maps from the EDS analysis showed the presence of C, O, and Cl suggesting the potential presence of MPs. The O/C ratio was used to assess potential oxidation degree. In addition, an evaluation of the toxicological effects of the potential MPs in the sewage effluent on Nile tilapia (Oreochromis niloticus) exposed to the effluent at two concentrations (50% and 75%) elicited a marked response in the endpoints evaluated; EROD activity, MDA (malondialdehyde), 8-oxo-2'-deoxyguanosine levels in and AChE (acetylcholinesterase) activity in the brain. Thus, the key results provide new insights into the use of clean technologies to combat global MP pollution in aquatic ecosystems.
    MeSH term(s) Animals ; Cichlids/metabolism ; Microplastics/metabolism ; Zinc Oxide/chemistry ; Plastics/metabolism ; Sewage ; Acetylcholinesterase/metabolism ; Ecosystem ; Nanoparticles
    Chemical Substances Microplastics ; Zinc Oxide (SOI2LOH54Z) ; Plastics ; Sewage ; Acetylcholinesterase (EC 3.1.1.7)
    Language English
    Publishing date 2023-06-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 280652-6
    ISSN 1873-6424 ; 0013-9327 ; 0269-7491
    ISSN (online) 1873-6424
    ISSN 0013-9327 ; 0269-7491
    DOI 10.1016/j.envpol.2023.121946
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Synthesis, Biological, and Molecular Docking Studies on 4,5,6,7-Tetrahydrobenzo[

    Kamal, Shimaa / Derbala, Hamed Ahmed / Alterary, Seham Soliman / Ben Bacha, Abir / Alonazi, Mona / El-Ashrey, Mohamed Kandeel / Eid El-Sayed, Nahed Nasser

    ACS omega

    2021  Volume 6, Issue 43, Page(s) 28992–29008

    Abstract: Initiation of colorectal carcinogenesis may be induced by chromosomal instability caused by oxidative stress or indirectly by bacterial infections. Moreover, proliferating tumor cells are characterized by reprogrammed glucose metabolism, which is ... ...

    Abstract Initiation of colorectal carcinogenesis may be induced by chromosomal instability caused by oxidative stress or indirectly by bacterial infections. Moreover, proliferating tumor cells are characterized by reprogrammed glucose metabolism, which is associated with upregulation of PDK1 and LDHA enzymes. In the present study, some 4,5,6,7-tetrahydrobenzo[
    Language English
    Publishing date 2021-10-25
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.1c04063
    Database MEDical Literature Analysis and Retrieval System OnLINE

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