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Article ; Online: Comment on 'The positive HIV result in a routine systemics screening in a dermatology clinic'.

Altunisik Toplu, Sibel / Altunisik, Nihal

2024

Language	English
Publishing date	2024-04-16
Publishing country	England
Document type	Journal Article
ZDB-ID	195504-4
ISSN	1365-2230 ; 0307-6938
ISSN (online)	1365-2230
ISSN	0307-6938
DOI	10.1093/ced/llae137
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Article ; Online: Commentary on "Potential risk factors for Varicella-zoster virus reactivation after COVID-19 vaccination".

Turkmen, Dursun / Altunisik, Nihal / Altunisik Toplu, Sibel

Journal of cosmetic dermatology

2022 Volume 21, Issue 8, Page(s) 3627–3628

MeSH term(s)	COVID-19/prevention & control ; COVID-19 Vaccines/adverse effects ; Herpesvirus 3, Human ; Humans ; Risk Factors ; Vaccination/adverse effects ; Varicella Zoster Virus Infection
Chemical Substances	COVID-19 Vaccines
Language	English
Publishing date	2022-04-12
Publishing country	England
Document type	Letter ; Comment
ZDB-ID	2280551-5
ISSN	1473-2165 ; 1473-2130
ISSN (online)	1473-2165
ISSN	1473-2130
DOI	10.1111/jocd.14976
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Article ; Online: Relationship between hand hygiene and cutaneous findings during COVID-19 pandemic.

Altunisik Toplu, Sibel / Altunisik, Nihal / Turkmen, Dursun / Ersoy, Yasemin

Journal of cosmetic dermatology

2020 Volume 19, Issue 10, Page(s) 2468–2473

Abstract: Background: In the current situation of the COVID-19 pandemic, healthcare workers (HCWs) have to comply with hygiene conditions and use gloves more frequently and for a longer period of time than they would previously to avoid infection and prevent ... ...

Abstract	Background: In the current situation of the COVID-19 pandemic, healthcare workers (HCWs) have to comply with hygiene conditions and use gloves more frequently and for a longer period of time than they would previously to avoid infection and prevent transmission. Aims: We aimed to characterize the adverse skin reactions occurring after hand hygiene and glove use in HCWs in a tertiary university hospital to determine the possible causative factors and whether the use of these measures is affected. Methods: Between April 15 and May 1, 2020, a cross-sectional survey was conducted, using online questionnaire, answered by HCWs in a tertiary university hospital. Results: The increase in general hand-skin problems during the pandemic period was statistically significant (P = .004). The most common symptom was dryness. During the pandemic period, 67 (24.3%) HCWs thought that the conditions were caused by glove use, and 197 (71.4%) thought that they were due to alcohol-based hand antiseptics. The incidence of other hand-skin conditions except for vesicles was statistically higher in women than in men (P < .001). Conclusions: Increased number of hand-skin conditions during the pandemic should not be ignored, since hand hygiene and glove use are expected to increase.
MeSH term(s)	Adult ; COVID-19/prevention & control ; Cross-Sectional Studies ; Dermatitis, Occupational/epidemiology ; Dermatitis, Occupational/etiology ; Female ; Gloves, Protective/adverse effects ; Hand Dermatoses/epidemiology ; Hand Dermatoses/etiology ; Hand Hygiene ; Health Personnel ; Humans ; Male
Keywords	covid19
Language	English
Publishing date	2020-08-26
Publishing country	England
Document type	Journal Article
ZDB-ID	2280551-5
ISSN	1473-2165 ; 1473-2130
ISSN (online)	1473-2165
ISSN	1473-2130
DOI	10.1111/jocd.13656
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Article: Multisystem Inflammatory Syndrome in Adults (MIS-A) Associated with SARS-CoV-2 Infection in a Young Adult Case from Turkey.

Altunisik Toplu, Sibel / Ersoy, Yasemin / Bayindir, Yasar / Kilic, Talat / Bayazit, Volkan

Medeniyet medical journal

2021 Volume 36, Issue 2, Page(s) 180–184

Abstract: Weeks and even months after recovering from the SARS-CoV-2 infection, clinically more severe cases are being reported, which are suggestive of COVID-19- related multisystemic inflammatory syndromes (MIS). Firstly on March 2020, this condition was ... ...

Abstract	Weeks and even months after recovering from the SARS-CoV-2 infection, clinically more severe cases are being reported, which are suggestive of COVID-19- related multisystemic inflammatory syndromes (MIS). Firstly on March 2020, this condition was reported to be COVID-19 related to children (MIS-C). Since June 2020, a syndrome similar to multisystem inflammatory syndrome in adults (MIS-A) came to be noticed in adults as well. We reported here a case of 24-year-old young woman who had gone to a hospital with abdominal pain and later developed a severe cough, followed by development of subconjunctival bleeding, pericardial effusion, pleural effusion, and intra-abdominal fluid that we deemed them to be acute multisystemic clinical symptoms, 47 days after she had undergone a COVID-19 infection of mild clinical severity. It should be kept in mind that a multisystemic inflammatory syndrome along with a delayed immune response during COVID-19 disease can be seen not only in children but also in young adults, and seemingly severe clinical and laboratory findings can improve by controlling the inflammatory process.
Language	English
Publishing date	2021-06-18
Publishing country	Turkey
Document type	Case Reports
ZDB-ID	3035195-9
ISSN	2149-4606 ; 2149-2042
ISSN (online)	2149-4606
ISSN	2149-2042
DOI	10.5222/MMJ.2021.95422
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Article: A silent outbreak due to

Duman, Yucel / Ersoy, Yasemin / Gursoy, Nafia Canan / Altunisik Toplu, Sibel / Otlu, Baris

Iranian journal of basic medical sciences

2020 Volume 23, Issue 1, Page(s) 46–50

Abstract: Objectives: Infections due to carbapenemase-producing : Materials and methods: Once an outbreak was suspected at the end of December 2017 in our intensive care unit (ICU), carbapenem resistance : Results: We investigate 21 carbapenem-resistant : ...

Abstract	Objectives: Infections due to carbapenemase-producing Materials and methods: Once an outbreak was suspected at the end of December 2017 in our intensive care unit (ICU), carbapenem resistance Results: We investigate 21 carbapenem-resistant Conclusion: The interventions that successfully controlled this outbreak were hand hygiene, tight contact prevention, good clean-up of the hospital environment and medical devices. As a result, we believe that it would be beneficial to take infection control measures to prevent the spread of these strains to the community and hospital settings.
Language	English
Publishing date	2020-04-25
Publishing country	Iran
Document type	Journal Article
ZDB-ID	2500485-2
ISSN	2008-3874 ; 2008-3866
ISSN (online)	2008-3874
ISSN	2008-3866
DOI	10.22038/IJBMS.2019.35269.8400
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Article: Relationship between hand hygiene and cutaneous findings during COVID-19 pandemic

Altunisik Toplu, Sibel / Altunisik, Nihal / Turkmen, Dursun / Ersoy, Yasemin

Abstract: BACKGROUND: In the current situation of the COVID-19 pandemic, healthcare workers (HCWs) have to comply with hygiene conditions and use gloves more frequently and for a longer period of time than they would previously to avoid infection and prevent ... ...

Abstract	BACKGROUND: In the current situation of the COVID-19 pandemic, healthcare workers (HCWs) have to comply with hygiene conditions and use gloves more frequently and for a longer period of time than they would previously to avoid infection and prevent transmission. AIMS: We aimed to characterize the adverse skin reactions occurring after hand hygiene and glove use in HCWs in a tertiary university hospital to determine the possible causative factors and whether the use of these measures is affected. METHODS: Between April 15 and May 1, 2020, a cross-sectional survey was conducted, using online questionnaire, answered by HCWs in a tertiary university hospital. RESULTS: The increase in general hand-skin problems during the pandemic period was statistically significant (P = .004). The most common symptom was dryness. During the pandemic period, 67 (24.3%) HCWs thought that the conditions were caused by glove use, and 197 (71.4%) thought that they were due to alcohol-based hand antiseptics. The incidence of other hand-skin conditions except for vesicles was statistically higher in women than in men (P < .001). CONCLUSIONS: Increased number of hand-skin conditions during the pandemic should not be ignored, since hand hygiene and glove use are expected to increase.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #693686
Database	COVID19

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Article ; Online: Relationship between hand hygiene and cutaneous findings during COVID‐19 pandemic

Altunisik Toplu, Sibel / Altunisik, Nihal / Turkmen, Dursun / Ersoy, Yasemin

Journal of Cosmetic Dermatology

2020 Volume 19, Issue 10, Page(s) 2468–2473

Keywords	Dermatology ; covid19
Language	English
Publisher	Wiley
Publishing country	us
Document type	Article ; Online
ZDB-ID	2280551-5
ISSN	1473-2130
ISSN	1473-2130
DOI	10.1111/jocd.13656
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Zs.A 6539: Show issues

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Article ; Online: Evaluation of chronic hepatitis B patients who voluntarily discontinued oral antiviral therapy: is there an answer to the controversial topic?

European journal of gastroenterology & hepatology

2024 Volume 36, Issue 4, Page(s) 438–444

Abstract: Objective: The uncertain treatment duration for nucleos(t)ide analogues (NA) used in the treatment of chronic hepatitis B (CHB) is an important problem for both patients and physicians. The aim of this study was to evaluate the determinants of virologic ...

Abstract	Objective: The uncertain treatment duration for nucleos(t)ide analogues (NA) used in the treatment of chronic hepatitis B (CHB) is an important problem for both patients and physicians. The aim of this study was to evaluate the determinants of virologic relapse (VR) and the optimum time of treatment discontinuation in the follow-up of CHB patients who voluntarily discontinued treatment after virological suppression was achieved under NA use. Methods: Data from 138 patients from 11 centers were included in this registry-based study. Factors associated with VR were investigated using multivariate Cox regression analysis. Results: Ninety-nine (71.7%) of the patients were HBeAg (Hepatitis B e antigen) negative. During the 24-month follow-up period after treatment discontinuation, VR occurred in 58.7% (n = 81) of all patients and 57.6% (n = 57) of HBeAg-negative patients. The duration of NA treatment was significantly shorter (cutoff 60 months) in HBeAg-negative patients who later developed VR. In addition, the duration of virologic remission achieved under NA treatment was significantly shorter (cutoff 52 months) in those who later developed VR. In the Cox multivariate regression model of HBeAg-negative patients, having less than 60 months of NA treatment (HR = 2.568; CI:1.280-5.148; P = 0.008) and the levels of alanine aminotransferase being equal to or higher than twice the upper level of normal at the beginning of treatment (HR = 3.753; CI:1.551-9.081; P = 0.003) were found to be statistically significant and independently associated with VR. Conclusion: The findings of this study may provide clinical guidance in terms of determining the most appropriate discontinuation time for NA.
MeSH term(s)	Humans ; Hepatitis B, Chronic/diagnosis ; Hepatitis B, Chronic/drug therapy ; Hepatitis B e Antigens ; Antiviral Agents/adverse effects ; Recurrence ; DNA, Viral ; Hepatitis B virus/genetics ; Hepatitis B Surface Antigens ; Treatment Outcome
Chemical Substances	Hepatitis B e Antigens ; Antiviral Agents ; DNA, Viral ; Hepatitis B Surface Antigens
Language	English
Publishing date	2024-02-23
Publishing country	England
Document type	Journal Article
ZDB-ID	1034239-4
ISSN	1473-5687 ; 0954-691X
ISSN (online)	1473-5687
ISSN	0954-691X
DOI	10.1097/MEG.0000000000002722
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Zs.A 2932: Show issues

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Article: Is peritoneal dialysis prior to kidney transplantation a risk factor for ureteral stenosis after adult to adult live kidney transplantation.

Kutlutürk, Koray / Şahin, Tevfik Tolga / Çimen, Serhan / Dalda, Yasin / Gönültaş, Fatih / Doğan, Sait Murat / Altunışık Toplu, Sibel / Ünal, Bülent / Pişkin, Turgut

Turkish journal of surgery

2020 Volume 36, Issue 1, Page(s) 33–38

Abstract: Objectives: Major urinary complications such as urinary leaks, stenosis or urinary tract infections after kidney transplantation can lead to graft or patient loss. The effect of peritoneal dialysis on post-kidney transplantation complications have been ... ...

Abstract	Objectives: Major urinary complications such as urinary leaks, stenosis or urinary tract infections after kidney transplantation can lead to graft or patient loss. The effect of peritoneal dialysis on post-kidney transplantation complications have been discussed but its effect on ureteral stenosis is unknown. In this study, it was aimed to analyze factors effecting major ureteral complications after living donor kidney transplantation and impact of peritoneal dialysis and double J-stents (JJ stents). Material and methods: This study included 116 adult to adult living donor kidney transplant patients. Factors effecting major urologic complications after living donor kidney transplantation were analyzed. The donors were primary relatives of the recipients. Results: Major urologic complications after living donor kidney transplantation was 8/116 (6.9%). Urinary leak was present in 2 (1.7%) patients. Ureteral stenosis was encountered in 6 (5.2%) patients. Double J stents were used in 84 (72.4%) of the cases. The effect of JJ ureteral stent was not statistically significant for urinary leak, ureteral stenosis (p= 0.074, p= 0.470, respectively). A total of 29 (25%) patients had peritoneal dialysis before kidney transplantation. Preoperative peritoneal dialyses and bacteriuria after kidney transplantation were independent risk factors for ureteral stenosis in multivariate analysis (p= 0.013, and p= 0.010 respectively). Conclusion: In the guidance of the results of the present study, peritoneal dialysis prior to kidney transplantation and bacteriuria are independent risk factors for ureteral stenosis after living donor kidney transplantation. JJ stents have no effect on urologic complications after living donor kidney transplantation.
Language	English
Publishing date	2020-03-18
Publishing country	Turkey
Document type	Journal Article
ISSN	2564-6850
ISSN	2564-6850
DOI	10.5578/turkjsurg.4605
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Article ; Online: Evaluation of clinical characteristics and outcomes of postoperative ınfections in living liver donors.

Kose, Adem / Altunisik Toplu, Sibel / Akbulut, Sami / Yasar, Seyma / Sarici, Kemal Baris / Duman, Yucel / Kutlu, Ramazan / Isik, Burak / Colak, Yusuf Ziya / Yilmaz, Sezai / Bayindir, Yasar

International journal of clinical practice

2021 Volume 75, Issue 8, Page(s) e14324

Abstract: Aim: To analyze developing infections after living donor hepatectomy (LDH) in living liver donors (LLDs).: Methods: Demographic and clinical characteristics of 1106 LLDs were retrospectively analyzed in terms of whether postoperative infection ... ...

Abstract	Aim: To analyze developing infections after living donor hepatectomy (LDH) in living liver donors (LLDs). Methods: Demographic and clinical characteristics of 1106 LLDs were retrospectively analyzed in terms of whether postoperative infection development. Therefore, LLDs were divided into two groups: with (n = 190) and without (n = 916) antimicrobial agent use. Results: The median age was 29.5 (min-max: 18-55). A total of 257 (23.2%) infection attacks (min-max: 1-8) was developed in 190 (17.2%) LLDs. The patients with the infection that were longer intensive care unit (ICU) and hospital stays, higher hospital admissions, emergency transplantation, invasive procedures for ERCP, PTC biloma, and abscess drainage, and the presence of relaparatomies and transcystic catheters. Infection attacks are derived from a 58.3% hepatobiliary system, 13.2% urinary system, 6.6% surgical site, and 5.8% respiratory system. The most common onset symptoms were fever, abdominal pain, nausea, and vomiting. A total of 125 positive results was detected from 77 patients with culture positivity. The most detected microorganisms from the cultures taken are Extended-Spectrum β-lactamases (ESBL) producing Klebsiella pneumonia (16.8%) and Escherichia coli (16%), Methicillin-Resistant Staphylococcus aureus [(MRSA) (9.6%)], Methicillin-susceptible S aureus [(MSSA) (9.6%)], and Pseudomonas aeruginosa (8.8%), respectively. The average number of ICU hospitalization days was 3 ± 2 (min 1-max 30, IQR:1) and hospitalization days was 14 ± 12 (min 3-max 138, IQR: 8). All infection attacks were successfully treated. No patients died because of infection or another surgical complication. Conclusion: Infections commonly observed infected biloma, cholangitis, and abscess arising from the biliary system and other nosocomial infections are the feared complications in LLDs. These infections should be managed multidisciplinary without delay and carefully.
MeSH term(s)	Adult ; Anti-Bacterial Agents/therapeutic use ; Cross Infection/drug therapy ; Humans ; Liver ; Living Donors ; Methicillin-Resistant Staphylococcus aureus ; Retrospective Studies ; Staphylococcal Infections/drug therapy
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2021-05-21
Publishing country	England
Document type	Journal Article
ZDB-ID	1386246-7
ISSN	1742-1241 ; 1368-5031
ISSN (online)	1742-1241
ISSN	1368-5031
DOI	10.1111/ijcp.14324
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