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Article ; Online: Impact of annual TB screening on stone quarry workers in high-incidence Portuguese municipalities.

Sousa, S / Santos, S / Alves, C M / Gonçalves, G / Carvalho, C / Duarte, R

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease

2024 Volume 28, Issue 3, Page(s) 136–141

Abstract: ... SETTING ... The Portuguese municipalities of Penafiel and Marco de Canaveses are high TB incidence areas, where stone quarry workers represent a vulnerable population ... OBJECTIVE ... To assess the ... ...

Abstract	<sec id="st1"><title>SETTING</title>The Portuguese municipalities of Penafiel and Marco de Canaveses are high TB incidence areas, where stone quarry workers represent a vulnerable population.</sec><sec id="st2"><title>OBJECTIVE</title>To assess the annual rate of TB infection (ARI) in stone quarry workers and to compare it with the TB notification rate in the general community.</sec><sec id="st3"><title>DESIGN</title>An annual TB infection screening strategy using interferon-gamma release assay (IGRA) was implemented in 2018 for workers from high-risk stone quarries. A prospective cohort was enrolled and workers screened in periods of 2 years were included. IGRA-positive workers were referred for preventive treatment. ARI was calculated as the proportion of workers with IGRA conversion.</sec><sec id="st4"><title>RESULTS</title>Of the 232 IGRA-negative workers in 2018, 20 tested positive in 2019 (8.6% ARI). Of 171 IGRA-negative workers in 2019, eight tested positive in 2021 (4.7% in 2 years). Two of the 150 IGRA-negative workers in 2021 tested positive in 2022 (1.3% ARI). ARI decreased by 84.9% between 2019 and 2022. In the two municipalities, the TB notification rate declined 23.9% between 2018 and 2021.</sec><sec id="st5"><title>CONCLUSION</title>A more pronounced reduction in ARI was observed among stone quarry workers regularly screened for TB infection compared to the notification rate among the general population in high-incidence municipalities. A screening strategy for high-risk populations, together with enforced community measures, could foster risk reduction in the community.</sec>.
MeSH term(s)	Humans ; Tuberculosis/epidemiology ; Prospective Studies ; Incidence ; Cities ; Portugal/epidemiology ; Interferon-gamma Release Tests ; Mass Screening ; Latent Tuberculosis/diagnosis
Language	English
Publishing date	2024-03-07
Publishing country	France
Document type	Journal Article
ZDB-ID	1385624-8
ISSN	1815-7920 ; 1027-3719
ISSN (online)	1815-7920
ISSN	1027-3719
DOI	10.5588/ijtld.23.0350
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Article ; Online: An investigation of TB infection and reinfection among stone quarry workers.

Sousa, S / Alves, C M / Macedo, R / Carvalho, C / Gonçalves, G / Duarte, R

Pulmonology

2023 Volume 29, Issue 6, Page(s) 570–572

MeSH term(s)	Humans ; Reinfection ; Tuberculosis ; Occupational Health
Language	English
Publishing date	2023-05-31
Publishing country	Spain
Document type	Letter
ZDB-ID	3009651-0
ISSN	2531-0437 ; 2531-0429
ISSN (online)	2531-0437
ISSN	2531-0429
DOI	10.1016/j.pulmoe.2023.05.004
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Article ; Online: Coffee shops, a hub for TB clusters?

Sousa, S / Macedo, R / Alves, C M / Carvalho, C / Gonçalves, G / Duarte, R

Pulmonology

2023 Volume 30, Issue 1, Page(s) 71–74

Language	English
Publishing date	2023-05-24
Publishing country	Spain
Document type	Letter
ZDB-ID	3009651-0
ISSN	2531-0437 ; 2531-0429
ISSN (online)	2531-0437
ISSN	2531-0429
DOI	10.1016/j.pulmoe.2023.04.007
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Article: Contextual and individual determinants of tooth loss in the Afro-descendant older adult populations of different countries: a scoping review.

Dos Santos, L R / Hugo, F N / Costa, C M / Brondani, M A / Coelho Alves, C M

Community dental health

2023 Volume 40, Issue 1, Page(s) 30–36

Abstract: Background: The Black population has poorer oral health than other racial groups; however, little is known about the mechanisms that explain this difference.: Objective: To study the association between race and tooth loss and map the evidence on ... ...

Abstract	Background: The Black population has poorer oral health than other racial groups; however, little is known about the mechanisms that explain this difference. Objective: To study the association between race and tooth loss and map the evidence on factors associated with tooth loss in Black older populations. Methods: Scoping review following the PRISMA Extension for Scoping Reviews conducted according to the recommendations of the Joanna Briggs Institute. A three-step search strategy was applied, and data were collected between April and July 2021. Searches were performed in the PubMed, Lilacs, and SciELO databases. The grey literature was searched using Google Scholar (https://www.scholar.google.com/). The reference lists of included studies were used as additional sources. Studies published in English and Portuguese of the association between tooth loss and different racial groups and the factors associated with tooth loss and tooth retention in Black older adult populations were included. Results: Twenty-one of 913 original articles published between 1995 and 2020 were included. Of these, 75% were research articles, 15% were reports, and 10% dissertations. Eighty per cent reported cross-sectional and 20% longitudinal data. African ancestry was associated with increased odds of tooth loss in older adult populations. Periodontal disease, female sex, and advanced age were the exposures most frequently associated with tooth loss. Conclusion: Race, educational level, advanced age, and oral diseases such as periodontitis are associated with increased tooth loss in Afro-descendant older populations.
MeSH term(s)	Aged ; Female ; Humans ; Cross-Sectional Studies ; Ethnicity ; Periodontal Diseases ; Periodontitis ; Tooth Loss/epidemiology
Language	English
Publishing date	2023-02-28
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	631156-8
ISSN	0265-539X
ISSN	0265-539X
DOI	10.1922/CDH_00121dosSantos07
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Article ; Online: Fusobacterium nucleatum and Prevotella in women with periodontitis and preterm birth.

Lima, K-M / Alves, C-M / Vidal, F-C / Gomes-Filho, I-S / Costa, J-C / Coletta, R-D / Rodrigues, V-P / Lopes, F-F

Medicina oral, patologia oral y cirugia bucal

2023 Volume 28, Issue 5, Page(s) e450–e456

Abstract: Background: Studies try to explain the hypothesis that maternal periodontitis may be associated with preterm birth.: Material and methods: This is a case-control study with 120, 40 cases (gestational age <37 weeks) and 80 controls (gestational age ≥ ... ...

Abstract	Background: Studies try to explain the hypothesis that maternal periodontitis may be associated with preterm birth. Material and methods: This is a case-control study with 120, 40 cases (gestational age <37 weeks) and 80 controls (gestational age ≥37 weeks), that were submitted to the clinical periodontal examination and subgingival biofilm collection. Bacterial DNA of subgingival biofilm was performed and processed by qPCR. Results: Periodontitis was statistically significant in the Case group (35%) when compared to the Control group (11.2%) and Gingival Bleeding Index (GBI), sites with PS ≥ 4mm and sites with CAL ≥ 5mm were statistically higher in the Case group (p < 0.05). The proportions of Pi (p = 0.026) and Fn (p = 0.041) of subgingival biofilm were higher in the Case group. A greater number of sites with PS ≥ 4mm (r = -0.202; p = 0.026) and CAL ≥ 5mm (r = -0.322; p < 0.001) were correlated to lower gestational age. Conclusions: Periodontitis, preterm delivery, and/or low birth weight may have a possible relationship based on clinical parameters and the ratio of Pi and Fn at periodontal sites.
MeSH term(s)	Infant, Newborn ; Humans ; Female ; Infant ; Fusobacterium nucleatum ; Prevotella ; Case-Control Studies ; Premature Birth ; Periodontitis/complications
Language	English
Publishing date	2023-09-01
Publishing country	Spain
Document type	Journal Article
ZDB-ID	2171573-7
ISSN	1698-6946 ; 1698-4447
ISSN (online)	1698-6946
ISSN	1698-4447
DOI	10.4317/medoral.25874
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Article ; Online: Systemic circulating inflammatory burden and periodontitis in adolescents.

Ribeiro, Cecilia C C / Carmo, Cadidja D S / Benatti, Bruno B / Casarin, Renato V C / Alves, C M C / Nascimento, Gustavo G / Moreira, A R O

Clinical oral investigations

2021 Volume 25, Issue 10, Page(s) 5855–5865

Abstract: Objectives: To analyze the association between systemic inflammatory burden of cardiovascular disease (CVD) risk and periodontitis in adolescents, including mediating pathways triggered by their common risk factors.: Materials and methods: Using a ... ...

Abstract	Objectives: To analyze the association between systemic inflammatory burden of cardiovascular disease (CVD) risk and periodontitis in adolescents, including mediating pathways triggered by their common risk factors. Materials and methods: Using a population-based sample study (n = 405) of Brazilian adolescents (17-18 years old), direct and mediation pathways triggered by "Socioeconomic Status," "Adiposity," Smoking, and "Blood Pressure" were modelled for the association between the "Systemic Circulating Inflammatory Burden of CVD Risk" (IL-1β, IL-6, IL-8, TNF-α) and the "Initial Periodontitis" (bleeding on probing (BoP), probing depth (PD) ≥ 4 mm, clinical attachment loss (CAL) ≥ 4 mm), both as continuous latent variables, using structural equation modeling. Sensitivity analysis was performed for the outcomes "Gingivitis" (visible plaque; BoP); "Moderate Periodontitis" (PD ≥ 5 mm and CAL ≥ 5 mm) and periodontitis (CDC-AAP case definition). Results: Higher "Systemic Circulating Inflammatory Burden of CVD Risk" was directly associated with higher "Initial Periodontitis" (standardized coefficient [SC] = 0.178, P value < 0.001). Lower "Socioeconomic Status" (SC = - 0.022, P value = 0.015) and Smoking (SC = 0.030, P value = 0.021) triggered the "Initial Periodontitis", mediated by "Systemic Circulating Inflammatory Burden of CVD Risk". Sensitivity analysis showed a dose-response relationship between "Systemic Circulating Inflammatory Burden of CVD Risk" and "Moderate Periodontitis" (SC = 0.323, P value = 0.021). Conclusions: "Systemic Circulating Inflammatory Burden of CVD Risk" appeared as an underlying mechanism of early periodontal breakdown in adolescents, also triggered by social vulnerability and smoking. Clinical relevance: The association between periodontitis and CVD in adulthood seems to establish much earlier in life than had been previously studied, giving impetus to preventive approaches focused on their common risk factors.
MeSH term(s)	Adolescent ; Adult ; Dental Plaque ; Gingivitis ; Humans ; Periodontal Attachment Loss ; Periodontitis/epidemiology ; Tumor Necrosis Factor-alpha
Chemical Substances	Tumor Necrosis Factor-alpha
Language	English
Publishing date	2021-03-24
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1364490-7
ISSN	1436-3771 ; 1432-6981
ISSN (online)	1436-3771
ISSN	1432-6981
DOI	10.1007/s00784-021-03891-y
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Zs.A 4788: Show issues

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Article: Socioeconomic inequalities and temporomandibular joint disorders in adolescents: contributions from a Maranhão cohort.

de Sousa, F S / Costa, E M / Alves, C M C / Queiroz, R C D S / Tonello, A S / Ribeiro, C C C / Thomaz, E B A F

Community dental health

2021 Volume 38, Issue 3, Page(s) 192–197

Abstract: Aim: To assess the prevalence of temporomandibular disorder (TMD) in adolescents and estimate possible associations with poverty.: Basic research design: A cross-sectional study nested within a prospective birth cohort study conducted in São Luís, ... ...

Abstract	Aim: To assess the prevalence of temporomandibular disorder (TMD) in adolescents and estimate possible associations with poverty. Basic research design: A cross-sectional study nested within a prospective birth cohort study conducted in São Luís, Maranhão, Brazil. Participants: 2,412 adolescents aged 18-19 years. Material and methods: The presence of TMD, classified according to the Fonseca Anamnestic Index, was used as the outcome. The following explanatory variables were assessed: gender, household head, paved/asphalted street, piped water, and socioeconomic background, based on the Brazilian Association of Market Research criteria and the poverty income ratio (PIR). Logistic regression analysis was performed with the estimation of odds ratios (OR) and 95% confidence intervals. Results: TMD was common (51.4%) and was associated with poverty, as it was more frequent among adolescents from social classes D-E (OR=2.60; 95% CI: 1.48-4.55) and C (OR=1.82; 95% CI: 1.12-2.99) compared to A/B, and among poor adolescents using the PIR (OR=1.50; 95% CI: 1.02-2.33). Conclusions: The prevalence of TMD in socioeconomically disadvantaged adolescents in São Luís is high, and these data allow the early identification of at-risk groups. We recommend carrying out other population-based studies, using diagnostic strategies with greater accuracy.
MeSH term(s)	Adolescent ; Brazil/epidemiology ; Cohort Studies ; Cross-Sectional Studies ; Humans ; Prevalence ; Prospective Studies ; Socioeconomic Factors ; Temporomandibular Joint Disorders/epidemiology
Language	English
Publishing date	2021-08-31
Publishing country	England
Document type	Journal Article
ZDB-ID	631156-8
ISSN	0265-539X
ISSN	0265-539X
DOI	10.1922/CDH_deSousa0028506
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Article ; Online: Detection of periodontal pathogens in mothers of preterm birth and/or low weight.

Calixto, N-R / Alves, C-M / Abreu, L-M / Thomaz, E-B / Vidal, F-C / Filho, I-S / Lopes, F-F

Medicina oral, patologia oral y cirugia bucal

2019 Volume 24, Issue 6, Page(s) e776–e781

Abstract: Background: The present study aims to estimate the possible relationship between periodontal pathogens in the oral cavity and the birth of Preterm Birth (PTB) and/or Low Birth Weight (LBW).: Material and methods: It's a case- control study with the ... ...

Abstract	Background: The present study aims to estimate the possible relationship between periodontal pathogens in the oral cavity and the birth of Preterm Birth (PTB) and/or Low Birth Weight (LBW). Material and methods: It's a case- control study with the subgengival biofilm samples were collected from four sites up deeper until 48 hours postpartum and were processes by Polymerase Chain Reaction (PCR) for presence the periodontal pathogens Prevotella intermedia (Pi), Fusobacterium nucleatum (Fn), Porphyromonas gingivalis (Pg), Treponema denticola (Td), Tannerella forsythia (Tf) e Aggregatibacter actinomycetemcomitans (Aa). The mothers were divided into case grup (babies weighing < 2500g and/or gestational age < 37 weeks) and control group (babies weighing ≥ 2500g and gestational age ≥ 37 weeks). Chi-square test and the measure of association obtained by Odds Ratio (OR) were used to estimate the association between the variables. Results: Microbial analyses results showed no significant association between PTB and LBW with most periodontal pathogens in the oral cavity, even with association with the clinical presence of periodontitis. Conclusions: given the high presence of periodontal pathogens in the biofilm subgengival of recent mothers, it is suggested that the findings of this research serve as the basis for future studies on the pathophysiology involved in the relationship between periodontitis and PTB and/or LBW.
MeSH term(s)	Aggregatibacter actinomycetemcomitans ; Female ; Humans ; Infant, Newborn ; Mothers ; Porphyromonas gingivalis ; Pregnancy ; Premature Birth ; Prevotella intermedia ; Treponema denticola
Language	English
Publishing date	2019-11-01
Publishing country	Spain
Document type	Journal Article
ZDB-ID	2171573-7
ISSN	1698-6946 ; 1698-4447
ISSN (online)	1698-6946
ISSN	1698-4447
DOI	10.4317/medoral.23135
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Article ; Online: Are sickle cell anaemia and sickle cell trait predictive factors for periodontal disease? A cohort study.

de Carvalho, H L C C / Thomaz, E B A F / Alves, C M C / Souza, S F C

Journal of periodontal research

2016 Volume 51, Issue 5, Page(s) 622–629

Abstract: Background and objective: Periodontal diseases are associated with bacterial challenge and the host immune response, and are also modulated by genetic factors. There is evidence that sickle cell anaemia (SCA) does not represent a risk factor for ... ...

Abstract	Background and objective: Periodontal diseases are associated with bacterial challenge and the host immune response, and are also modulated by genetic factors. There is evidence that sickle cell anaemia (SCA) does not represent a risk factor for periodontal diseases. However, it is still unclear whether the heterozygous condition [sickle cell trait (SCT)] is associated with periodontal diseases. SCT is a genetic condition that can cause vaso-occlusive events, which may be associated with a propensity to bacterial infections. The aim of this study was to investigate the association of SCA and SCT with periodontal diseases by evaluating clinical and radiographic characteristics. Material and methods: The sample (n = 369) was selected and divided into two groups: exposed groups [HbSS (SCA genotype) and HbAS (SCT genotype) = 246] and a nonexposed group (HbAA = 123). HbAA consisted of individuals without SCA and SCT. The clinical parameters evaluated were plaque index, gingival index, calculus index, clinical probing depth, clinical attachment level, gingival recession, tooth mobility and furcation involvement. The percentage of alveolar bone loss was measured using a Schei ruler. Binomial and Poisson regressions were used to estimate correlations of interest (α = 0.05). Results: None of the periodontal parameters was associated with SCA. SCT was associated with gingivitis (p = 0.041) and periodontitis (p = 0.002). Individuals with SCT had a lower plaque index (p = 0.044) but a higher calculus index (p = 0.003) and greater alveolar bone loss (p = 0.010) compared with subjects in the HbAA group. Conclusions: SCT can act as a predictor for establishment of periodontal diseases. There was no correlation between SCA and periodontal diseases.
Language	English
Publishing date	2016-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	390953-0
ISSN	1600-0765 ; 0022-3484
ISSN (online)	1600-0765
ISSN	0022-3484
DOI	10.1111/jre.12342
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Article ; Online: Lower birthweight, shorter breastfeeding and lack of primary health care contributed to higher pacifier use in a birth cohort.

Martins, R F M / Lima, A A S J / Ribeiro, C C C / Alves, C M C / da Silva, A A M / Thomaz, E B A F

Acta paediatrica (Oslo, Norway : 1992)

2018

Language	English
Publishing date	2018-05-11
Publishing country	Norway
Document type	Journal Article
ZDB-ID	203487-6
ISSN	1651-2227 ; 0365-1436 ; 0803-5253
ISSN (online)	1651-2227
ISSN	0365-1436 ; 0803-5253
DOI	10.1111/apa.14392
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