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  1. Article ; Online: Outcomes of Patients With Cardiogenic Shock in Hub and Spoke Centers: The importance of Protocol Standardization at a Network Level.

    Alviar, Carlos L / Hall, Sylvie / Mebazaa, Alexandre

    Journal of cardiac failure

    2024  Volume 30, Issue 4, Page(s) 576–579

    MeSH term(s) Humans ; Shock, Cardiogenic/diagnosis ; Shock, Cardiogenic/therapy ; Heart Failure ; Stroke
    Language English
    Publishing date 2024-02-16
    Publishing country United States
    Document type Editorial
    ZDB-ID 1281194-4
    ISSN 1532-8414 ; 1071-9164
    ISSN (online) 1532-8414
    ISSN 1071-9164
    DOI 10.1016/j.cardfail.2024.01.007
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4340: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  2. Article ; Online: Sedation strategies in patients undergoing extracorporeal cardiopulmonary resuscitation.

    Alviar, Carlos L / van Diepen, Sean

    European heart journal. Acute cardiovascular care

    2023  Volume 12, Issue 4, Page(s) 257–259

    MeSH term(s) Humans ; Cardiopulmonary Resuscitation ; Heart Arrest/therapy ; Treatment Outcome ; Retrospective Studies
    Language English
    Publishing date 2023-03-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 2663340-1
    ISSN 2048-8734 ; 2048-8726
    ISSN (online) 2048-8734
    ISSN 2048-8726
    DOI 10.1093/ehjacc/zuad028
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  3. Article ; Online: A case report of sodium azide-induced myopericarditis.

    Tarabanis, Constantine / Banco, Darcy / Keller, Norma M / Bangalore, Sripal / Alviar, Carlos L

    European heart journal. Case reports

    2024  Volume 8, Issue 4, Page(s) ytae134

    Abstract: Background: Sodium azide exposures are rare but can be lethal as the substance inhibits complex IV in the electron transport chain, blocking adenosine-triphosphate (ATP) synthesis. Sodium azide is mostly used as a propellant in vehicular airbags but is ... ...

    Abstract Background: Sodium azide exposures are rare but can be lethal as the substance inhibits complex IV in the electron transport chain, blocking adenosine-triphosphate (ATP) synthesis. Sodium azide is mostly used as a propellant in vehicular airbags but is also used in laboratory, pharmacy, and industrial settings. No known antidote exists and its cardiotoxic effects are poorly described in the literature.
    Case summary: We describe the case of a 31-year-old patient with major depressive disorder presenting with altered mental status after ingestion of an unknown amount of sodium azide. Although initially chest pain free, she developed pleuritic chest pain 48 h after ingestion. This was accompanied by new diffuse ST elevations on the electrocardiogram and serum troponin elevations concerning for myopericarditis. Treatment was pursued with a 14-day course of colchicine resulting in complete symptom resolution within 4 days of treatment initiation. The patient's transthoracic echocardiogram was only notable for a preserved left ventricular ejection fraction (LVEF).
    Discussion: Cardiac toxicity after sodium azide ingestion usually occurs days after ingestion and has been previously described in the forms of heart failure with reduced ejection fraction complicated by cardiogenic shock. We describe the first case of sodium azide-induced myopericarditis with a preserved LVEF treated with colchicine. Colchicine is an established treatment for pericarditis, but its inhibition of endocytosis, an ATP-dependent cellular function, could be mechanistically relevant to this case.
    Language English
    Publishing date 2024-03-20
    Publishing country England
    Document type Case Reports
    ISSN 2514-2119
    ISSN (online) 2514-2119
    DOI 10.1093/ehjcr/ytae134
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  4. Article ; Online: Multimodality imaging in cardiogenic shock: state-of-the art.

    Tavazzi, Guido / Corradi, Francesco / Vandenbriele, Christophe / Alviar, Carlos L

    Current opinion in critical care

    2023  Volume 29, Issue 4, Page(s) 381–391

    Abstract: Purpose of review: There is emerging evidence on the role of the multimodality imaging in the setting of cardiogenic shock. The utility of different imaging modalities, along with their pitfalls and limitations, and their integration in a ... ...

    Abstract Purpose of review: There is emerging evidence on the role of the multimodality imaging in the setting of cardiogenic shock. The utility of different imaging modalities, along with their pitfalls and limitations, and their integration in a multiparametric approach are discussed in the current review.
    Recent findings: The evaluation of congestion and perfusion in patients with shock has allowed a better understanding of the underlying physiopathological mechanisms. Integration of echocardiography, using more physiological parameters, with lung ultrasound, as well as the Doppler evaluation of abdominal blood flow dynamics, has led to a better stratification in patinas with hemodynamic instability.
    Summary: Although validation of the integrated approaches and single parameters are needed, the physiopathological-driven approach using ultrasound in patients with cardiogenic shock on top of the clinical and biochemical evaluation, may aid to a quicker and more detailed evaluation of patient's phenotype.
    MeSH term(s) Humans ; Shock, Cardiogenic/diagnostic imaging ; Shock ; Hemodynamics/physiology ; Echocardiography
    Language English
    Publishing date 2023-06-22
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 1235629-3
    ISSN 1531-7072 ; 1070-5295
    ISSN (online) 1531-7072
    ISSN 1070-5295
    DOI 10.1097/MCC.0000000000001068
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4999: Show issues Location:
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  5. Article ; Online: Intracardiac Versus Transesophageal Echocardiography Guided Percutaneous Debulking of Tricuspid Endocarditis.

    Zhang, Robert S / Bailey, Eric / Maqsood, Muhammad H / Harari, Rafael / Bernard, Samuel / Xia, Yuhe / Keller, Norma / Alviar, Carlos L / Bangalore, Sripal

    The American journal of cardiology

    2024  Volume 217, Page(s) 141–143

    MeSH term(s) Humans ; Echocardiography, Transesophageal ; Cytoreduction Surgical Procedures ; Endocarditis/diagnosis ; Endocarditis/surgery ; Heart ; Endocarditis, Bacterial/diagnosis ; Endocarditis, Bacterial/surgery
    Language English
    Publishing date 2024-02-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80014-4
    ISSN 1879-1913 ; 0002-9149
    ISSN (online) 1879-1913
    ISSN 0002-9149
    DOI 10.1016/j.amjcard.2024.01.036
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    Ui IV Zs.73: Show issues Location:
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  6. Article ; Online: Explainable SHAP-XGBoost models for in-hospital mortality after myocardial infarction.

    Tarabanis, Constantine / Kalampokis, Evangelos / Khalil, Mahmoud / Alviar, Carlos L / Chinitz, Larry A / Jankelson, Lior

    Cardiovascular digital health journal

    2023  Volume 4, Issue 4, Page(s) 126–132

    Abstract: Background: A lack of explainability in published machine learning (ML) models limits clinicians' understanding of how predictions are made, in turn undermining uptake of the models into clinical practice.: Objective: The purpose of this study was to ...

    Abstract Background: A lack of explainability in published machine learning (ML) models limits clinicians' understanding of how predictions are made, in turn undermining uptake of the models into clinical practice.
    Objective: The purpose of this study was to develop explainable ML models to predict in-hospital mortality in patients hospitalized for myocardial infarction (MI).
    Methods: Adult patients hospitalized for an MI were identified in the National Inpatient Sample between January 1, 2012, and September 30, 2015. The resulting cohort comprised 457,096 patients described by 64 predictor variables relating to demographic/comorbidity characteristics and in-hospital complications. The gradient boosting algorithm eXtreme Gradient Boosting (XGBoost) was used to develop explainable models for in-hospital mortality prediction in the overall cohort and patient subgroups based on MI type and/or sex.
    Results: The resulting models exhibited an area under the receiver operating characteristic curve (AUC) ranging from 0.876 to 0.942, specificity 82% to 87%, and sensitivity 75% to 87%. All models exhibited high negative predictive value ≥0.974. The SHapley Additive exPlanation (SHAP) framework was applied to explain the models. The top predictor variables of increasing and decreasing mortality were age and undergoing percutaneous coronary intervention, respectively. Other notable findings included a decreased mortality risk associated with certain patient subpopulations with hyperlipidemia and a comparatively greater risk of death among women below age 55 years.
    Conclusion: The literature lacks explainable ML models predicting in-hospital mortality after an MI. In a national registry, explainable ML models performed best in ruling out in-hospital death post-MI, and their explanation illustrated their potential for guiding hypothesis generation and future study design.
    Language English
    Publishing date 2023-06-14
    Publishing country United States
    Document type Journal Article
    ISSN 2666-6936
    ISSN (online) 2666-6936
    DOI 10.1016/j.cvdhj.2023.06.001
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  7. Article ; Online: How to unload the left ventricle during veno-arterial extracorporeal membrane oxygenation.

    Tavazzi, Guido / Alviar, Carlos L / Colombo, Costanza Natalia Julia / Dammassa, Valentino / Price, Susanna / Vandenbriele, Christophe

    European heart journal. Cardiovascular Imaging

    2023  Volume 24, Issue 6, Page(s) 696–698

    MeSH term(s) Humans ; Extracorporeal Membrane Oxygenation ; Heart Ventricles/diagnostic imaging ; Shock, Cardiogenic/diagnostic imaging ; Shock, Cardiogenic/therapy
    Language English
    Publishing date 2023-04-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 2638345-7
    ISSN 2047-2412 ; 2047-2404
    ISSN (online) 2047-2412
    ISSN 2047-2404
    DOI 10.1093/ehjci/jead061
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5614: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  8. Article ; Online: Network meta-analysis of temporary mechanical circulatory support in acute myocardial infarction cardiogenic shock.

    Jentzer, Jacob C / Watanabe, Atsuyuki / Kuno, Toshiki / Bangalore, Sripal / Alviar, Carlos L

    American heart journal

    2023  Volume 266, Page(s) 184–187

    Abstract: We performed a network meta-analysis of 11 published randomized clinical trials examining the use of temporary mechanical circulatory support (MCS) devices in adults with acute myocardial infarction cardiogenic shock, including 1,053 total patients with ... ...

    Abstract We performed a network meta-analysis of 11 published randomized clinical trials examining the use of temporary mechanical circulatory support (MCS) devices in adults with acute myocardial infarction cardiogenic shock, including 1,053 total patients with an observed in-hospital or 30-day mortality of 40.4%. None of the temporary MCS devices was associated with lower in-hospital or 30-day mortality compared with initial medical therapy or any other MCS device, either individually or in combination. These data do not support the routine use of temporary MCS devices for the purpose of reducing short-term mortality in unselected patients with acute myocardial infarction cardiogenic shock.
    MeSH term(s) Adult ; Humans ; Shock, Cardiogenic/therapy ; Shock, Cardiogenic/complications ; Network Meta-Analysis ; Heart-Assist Devices ; Myocardial Infarction/complications ; Myocardial Infarction/therapy ; Intra-Aortic Balloon Pumping ; Treatment Outcome
    Language English
    Publishing date 2023-08-15
    Publishing country United States
    Document type Meta-Analysis ; Journal Article
    ZDB-ID 80026-0
    ISSN 1097-6744 ; 0002-8703
    ISSN (online) 1097-6744
    ISSN 0002-8703
    DOI 10.1016/j.ahj.2023.08.002
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    Ui IV Zs.15: Show issues Location:
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  9. Article ; Online: Tricuspid valve vegetation debulking using the AngioVac system.

    Bangalore, Sripal / Alviar, Carlos L / Vlahakis, Susan / Keller, Norma

    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

    2021  Volume 98, Issue 3, Page(s) E475–E477

    Abstract: Tricuspid valve endocarditis with recurrent septic pulmonary emboli is an indication for surgery. We present the case of a 36-year old man with tricuspid valve endocarditis and septic pulmonary emboli with percutaneous extraction of the vegetation. We ... ...

    Abstract Tricuspid valve endocarditis with recurrent septic pulmonary emboli is an indication for surgery. We present the case of a 36-year old man with tricuspid valve endocarditis and septic pulmonary emboli with percutaneous extraction of the vegetation. We discuss the nuances of such an approach and the need for more evidence in the management of these complex patients.
    MeSH term(s) Adult ; Cytoreduction Surgical Procedures ; Endocarditis/diagnostic imaging ; Endocarditis/surgery ; Endocarditis, Bacterial/diagnostic imaging ; Endocarditis, Bacterial/surgery ; Humans ; Male ; Treatment Outcome ; Tricuspid Valve/diagnostic imaging ; Tricuspid Valve/surgery
    Language English
    Publishing date 2021-02-10
    Publishing country United States
    Document type Case Reports
    ZDB-ID 1459995-8
    ISSN 1522-726X ; 1522-1946
    ISSN (online) 1522-726X
    ISSN 1522-1946
    DOI 10.1002/ccd.29519
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    Zs.A 1226: Show issues Location:
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  10. Article ; Online: Resource use among patients with transcatheter cardiac valve procedures admitted to contemporary cardiac intensive care units: insights from CCCTN.

    Bhatt, Ankeet S / Berg, David D / Palazzolo, Michael G / Alviar, Carlos L / Bohula, Erin A / Morrow, David A

    European heart journal. Acute cardiovascular care

    2023  Volume 13, Issue 2, Page(s) 245–246

    MeSH term(s) Humans ; Intensive Care Units ; Hospitalization ; Cardiac Surgical Procedures ; Heart Valves ; Aortic Valve Stenosis ; Treatment Outcome
    Language English
    Publishing date 2023-10-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 2663340-1
    ISSN 2048-8734 ; 2048-8726
    ISSN (online) 2048-8734
    ISSN 2048-8726
    DOI 10.1093/ehjacc/zuad118
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