LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 8 of total 8

Search options

  1. Article ; Online: Does Inclusion of Emergency Medicine (EM) Residents in ECG Screening for STEMI Change the Time to Catheterization Lab Activation?

    Aly, Sarah / Coolahan, Kelsey / Tomlinson, Kirk / Grossman, Duncan / Bove, Joseph / Hochman, Steven

    Critical pathways in cardiology

    2023  Volume 22, Issue 2, Page(s) 50–53

    Abstract: Background: Emergency medicine physicians must rapidly obtain and interpret an electrocardiogram (ECG) to quickly identify life-threatening cardiac emergencies such as ST-elevation myocardial infarction (STEMI). Although ECG interpretation is a critical ...

    Abstract Background: Emergency medicine physicians must rapidly obtain and interpret an electrocardiogram (ECG) to quickly identify life-threatening cardiac emergencies such as ST-elevation myocardial infarction (STEMI). Although ECG interpretation is a critical component of residency education, few high-powered studies exploring the accuracy of resident ECG interpretation exist.
    Objectives: This study aims to evaluate whether or not the inclusion of Third Year Emergency Medicine Resident ECG interpretations is noninferior to attending-only ECG interpretations in regard to time to STEMI activation.
    Methods: This was a retrospective noninferiority study of STEMI activation times before and after the inclusion of Third Year Emergency Medicine Resident resident ECG interpretations into the workflow at an academic, urban tertiary care center between November 2020 and April 2022, excluding prehospital activations. The primary outcome was the proportion of successful STEMI activations initiated within 5 minutes of ECG completion. An absolute decrease of 10% between groups was chosen as the noninferiority margin.
    Results: In the attending-only group, 26 (66.7%) cases resulted in successful STEMI activations compared to 31 cases (77.5%) in the combined group. The proportion of successful STEMI activations did not differ with resident screening, X 2 = 1.15, P = 0.28. The absolute difference between groups' successful activations was an increase of 11%, which lies within the noninferiority margin (+11%, 95% confidence interval, -8.68% to 30.7%). Average times to STEMI activation in the attending-only and combined groups were 7.59 minutes (Standard Deviation [SD], 10.19) and 5.13 minutes (SD, 6.95), respectively. Average door-to-balloon times for those undergoing Percutaneous Coronary Intervention were 72.74 minutes (SD, 20.76) in the attending-only group and 89.90 minutes (SD, 67.74) in the combination group. Two sample t-test showed no statistically significant difference between the 2 groups for average time to STEMI activation (difference = 2.46 minutes, 95% CI, -1.46 to 6.38) and average door-to-balloon time (difference = 17.16, 95% CI, -39.73 to 5.41).
    Conclusion: The inclusion of emergency medicine PGY-3 residents in the ECG screening workflow is noninferior to attending-only interpretation of ECGs with regard to STEMI activation time.
    MeSH term(s) Humans ; ST Elevation Myocardial Infarction ; Emergency Medical Services ; Retrospective Studies ; Myocardial Infarction/diagnosis ; Angioplasty, Balloon, Coronary ; Time Factors ; Electrocardiography ; Emergency Medicine
    Language English
    Publishing date 2023-04-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2079676-6
    ISSN 1535-2811 ; 1535-282X
    ISSN (online) 1535-2811
    ISSN 1535-282X
    DOI 10.1097/HPC.0000000000000320
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 5660: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Health services access, utilization, and barriers for Arabic-speaking refugees resettled in Connecticut, USA.

    Elreichouni, Ali / Aly, Sarah / Maciejewski, Kaitlin / Salem, Islam / Ghossein, Noah / Mankash, M Salah / Dziura, James / Mowafi, Hani

    BMC health services research

    2022  Volume 22, Issue 1, Page(s) 1337

    Abstract: Background: Arabic-speaking refugees are the largest group of refugees arriving in the United States since 2008, yet little is known about their rates of healthcare access, utilization, and satisfaction after the end of the Refugee Medical Assistance ( ... ...

    Abstract Background: Arabic-speaking refugees are the largest group of refugees arriving in the United States since 2008, yet little is known about their rates of healthcare access, utilization, and satisfaction after the end of the Refugee Medical Assistance (RMA) period.
    Methods: This study was a cross-sectional observational study. From January to December 2019, a household survey was conducted of newly arrived Arabic-speaking refugees in Connecticut between 2016 and 2018. Households were interviewed in Arabic either in person or over the phone by one of five researchers. Descriptive statistics were generated for information collected on demographics, prevalence of chronic conditions, patterns of health seeking behavior, insurance status and patient satisfaction using the Patient Satisfaction Questionnaire (PSQ-18).
    Results: Sixty-five households responded to the survey representing 295 Arabic-speaking refugees - of which 141 (48%) were children. Forty-seven households (72%) reported 142 chronic medical conditions among 295 individuals, 62 persons (21%) needed daily medication, 285 (97%) persons were insured. Median patient satisfaction was > 4.0 out of 5 for 6 of 7 domains of the PSQ-18 but wide variation (scores from 1.0 - 5.0).
    Conclusion: Arabic-speaking refugees in Connecticut participating in this study were young. The majority remained insured after their Refugee Medical Assistance lapsed. They expressed median high satisfaction with health services but with wide variation. Inaccessibility of health services in Arabic and difficulty obtaining medications remain areas in need of improvement.
    MeSH term(s) Child ; United States ; Humans ; Refugees ; Cross-Sectional Studies ; Connecticut ; Health Services ; Health Services Accessibility
    Language English
    Publishing date 2022-11-11
    Publishing country England
    Document type Observational Study ; Journal Article
    ZDB-ID 2050434-2
    ISSN 1472-6963 ; 1472-6963
    ISSN (online) 1472-6963
    ISSN 1472-6963
    DOI 10.1186/s12913-022-08733-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Pubertal consumption of R. badensis subspecies acadiensis modulates LPS-induced immune responses and gut microbiome dysbiosis in a sex-specific manner.

    Yahfoufi, Nour / Kadamani, Anthony K / Aly, Sarah / Al Sharani, Sara / Liang, Jacky / Butcher, James / Stintzi, Alain / Matar, Chantal / Ismail, Nafissa

    Brain, behavior, and immunity

    2022  Volume 107, Page(s) 62–75

    Abstract: Puberty is a critical period of development characterized by significant brain remodeling and increased vulnerability to immune challenges. Exposure to an immune challenge such as LPS during puberty can result in inflammation and gut dysbiosis which may ... ...

    Abstract Puberty is a critical period of development characterized by significant brain remodeling and increased vulnerability to immune challenges. Exposure to an immune challenge such as LPS during puberty can result in inflammation and gut dysbiosis which may lead to altered brain functioning and psychiatric illnesses later in life. However, treatment with probiotics during puberty has been found to mitigate LPS-induced peripheral and central inflammation, prevent LPS-induced changes to the gut microbiota and protect against enduring behavioural disorders in a sex-specific manner. Recent findings from our laboratory revealed that pubertal R. badensis subspecies acadiensis (R. badensis subsp. acadiensis) treatment prevents LPS-induced depression-like behavior and alterations in 5HT1A receptor expression in a sex-specific manner. However, the underlying mechanism remains unclear. Thus, the aim of this study was to gain mechanistic insights and to investigate the ability of R. badensis subsp. acadiensis consumption during puberty to mitigate the effects of LPS treatment on the immune system and the gut microbiome. Our results revealed that pubertal treatment with R. badensis subsp. acadiensis reduced sickness behaviors in females more than males in a time-specific manner. It also mitigated LPS-induced increases in pro-inflammatory cytokines in the blood and in TNFα mRNA expression in the prefrontal cortex and the hippocampus of female mice. There were sex-dependent differences in microbiome composition that persisted after LPS injection or R. badensis subsp. acadiensis consumption. R. badensis subsp. acadiensis had greater impact on the microbiota of male mice but female microbiota's were more responsive to LPS treatment. This suggested that female mice microbiota's may be more prone to modulation by this probiotic. These findings emphasize the sex-specific effects of probiotic use during puberty on the structure of the gut microbiome and the immune system and highlight the critical role of gut colonization with probiotics during adolescence on immunomodulation and prevention of the enduring effects of infections.
    MeSH term(s) Female ; Male ; Mice ; Animals ; Illness Behavior ; Lymphatic System ; Immunity
    Language English
    Publishing date 2022-09-26
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639219-2
    ISSN 1090-2139 ; 0889-1591
    ISSN (online) 1090-2139
    ISSN 0889-1591
    DOI 10.1016/j.bbi.2022.09.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2276: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 327: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Adolescent use of potential novel probiotic

    Yahfoufi, Nour / Ah-Yen, Emily G / Chandrasegaram, Rajini / Aly, Sarah / Murack, Michael / Kadamani, Anthony K / Matar, Chantal / Ismail, Nafissa

    Comprehensive psychoneuroendocrinology

    2021  Volume 7, Page(s) 100063

    Abstract: Adolescence is a critical period of development during which the brain undergoes significant remodeling that impacts behavior later in life. Exposure to stress, and especially immune challenge, during this period triggers changes in brain function ... ...

    Abstract Adolescence is a critical period of development during which the brain undergoes significant remodeling that impacts behavior later in life. Exposure to stress, and especially immune challenge, during this period triggers changes in brain function resulting in the development of mental disorders in adulthood, such as depression and anxiety. Previous studies from our laboratory have shown that a single exposure to LPS (lipopolysaccharide) during puberty causes enduring depression-like behaviour in females and anxiety-like behaviours in males. However, administration of probiotics during puberty blocked the enduring effects of LPS on depression-like and anxiety-like behaviors in female and male mice, respectively. These results suggest that the gut microbiome is a mediator of the effects of stress on mental health. The objective of the current study is to examine the effectiveness of a novel probiotic
    Language English
    Publishing date 2021-06-05
    Publishing country England
    Document type Journal Article
    ISSN 2666-4976
    ISSN (online) 2666-4976
    DOI 10.1016/j.cpnec.2021.100063
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Article ; Online: Breast and Cervical Cancer Screening among US and non US Born African American Muslim Women in New York City.

    Zorogastua, Karent / Sriphanlop, Pathu / Reich, Alyssa / Aly, Sarah / Cisse, Aminata / Jandorf, Lina

    AIMS public health

    2017  Volume 4, Issue 1, Page(s) 78–93

    Abstract: Purpose: Health disparities related to breast and cervical cancer among African American and African-born Muslim women in the United States have been identified in previous literature. Our study aimed at exploring the breast and cervical screening rates ...

    Abstract Purpose: Health disparities related to breast and cervical cancer among African American and African-born Muslim women in the United States have been identified in previous literature. Our study aimed at exploring the breast and cervical screening rates and factors that influence this population's disposition to adhere to cancer screening exams.
    Methods: Mixed methods were used to collect data with African American and African-born Muslim women in New York City. Data were collected from a total of 140 women; among them, 40 participated in four focus groups.
    Findings: Focus groups revealed nine themes: healthcare practices; lack of knowledge/misconceptions; negative perceptions and fear; time; modesty; role of religion; role of men; role of community; stigma and shame. Among 130 women who reported their cancer screening status, 72.3% of those age 21 and over were adherent to cervical cancer screening; 20.0% never had a Pap test. Among women age 40 and over, 80.2% reported adherence to recommended mammogram; 12.8% never had one. Among women under age 40, 52.2% had their last clinical breast exam (CBE) less than three years ago. Among women age 40 and over, 75.0% were adherent to yearly CBE.
    Conclusions: While rates of screenings were above the national average and higher than expected, specific barriers and facilitators related to religious and health beliefs and attitudes that influence the decision to adhere to screening were revealed. These factors should be further explored and addressed to inform future research and strategies for promoting regular breast and cervical cancer screenings.
    Language English
    Publishing date 2017-02-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2777115-5
    ISSN 2327-8994 ; 2327-8994
    ISSN (online) 2327-8994
    ISSN 2327-8994
    DOI 10.3934/publichealth.2017.1.78
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Book ; Article ; Online: Disaggregating faf2 data for California

    Aly, Sarah E. / Regan, Amelia

    2009  

    Abstract: The Freight Analysis Framework Version 2 (FAF2) data estimates commodity flows and related freight transportation activity among states, sub-state regions, and major international gateways (FHWA 2006). The FAF2 commodity flow origin-destination database ... ...

    Abstract The Freight Analysis Framework Version 2 (FAF2) data estimates commodity flows and related freight transportation activity among states, sub-state regions, and major international gateways (FHWA 2006). The FAF2 commodity flow origin-destination database includes tons and value of commodity movements among regions by mode of transportation and type of commodity. The FAF2 data for the State of California is represented through a Commodity Origin-Destination Database comprising aggregated data for five major FAF2 zones. These zones are: Los Angeles, San Diego, Sacramento, San Jose, and “the remainder of California” and they encompass a total of 58 counties. Disaggregating such data from a 5 zone level to a 58 county level can significantly enhance the understanding of freight flow volume and distribution in California which can be used to improve state freight flow planning. A variety of methods for the disaggregation of the FAF2 data have been developed. Some techniques use socioeconomic factors such as employment and population as a basis for their disaggregation procedures, while others use a Truck Vehicle Miles Traveled (TVMT) approach. This paper presents an analysis of a revised Truck Vehicle Miles Traveled (TVMT) based method (Rowinski et al 2007) to disaggregate the FAF2 data pertaining to California for the year 2002. This work is part of a larger project aimed towards developing a freight analysis framework for the State of California. The main factor used for this disaggregation is the ratio of TVMT within the county level to the TVMT within the respective FAF2 zone level. The analysis was carried out using this factor for both the Origins and Destinations as illustrated in a numerical example. The results of this work provide a unique insight to freight flow volume and distribution within the State of California. The methodology has proven to be an efficient approach to disaggregating FAF2 data and can be easily applied to future projections.
    Keywords Research Methods/ Statistical Methods ; Resource /Energy Economics and Policy
    Subject code 333
    Language English
    Publishing country us
    Document type Book ; Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  7. Article ; Online: Relation between Zinc Level and One Year Mortality among Elderly Patients with Heart Failure

    Nora Abdel-Khalek Abdel-Salam*, Walaa Wessam Aly*, Sarah Ahmed Hamza*, Hossam Mosfata Fahmy**, Ahmed Kamel Mortagy*

    Egyptian Journal of Hospital Medicine , Vol 54, Pp 11-

    2014  Volume 14

    Abstract: Background: Zinc (Zn) deficiency in endothelial cells potentiates the inflammatory response mediated by certain lipids and cytokines, possibly via mechanisms associated with increased cellular oxidative stress. Objectives: To assess the relation between ... ...

    Abstract Background: Zinc (Zn) deficiency in endothelial cells potentiates the inflammatory response mediated by certain lipids and cytokines, possibly via mechanisms associated with increased cellular oxidative stress. Objectives: To assess the relation between zinc level and one year mortality among elderly patients with heart failure. Patients and Methods: Serum zinc level was measured in 100 elderly patients with heart failure diagnosed by Criteria of New York Heart Association (NYHA). Patients were followed by telephone for one year to assess relation between Zinc level and one year mortality among elderly patients with heart failure. Results: Higher mortality percentage was found among patients with high level of zinc but there was no statistical significant difference. (P-value >0.05). And non significant relation was found between mean level of zinc and mortality, between age and Zn, and between Ejection Fraction (EF) and Zn. Zn level was lower among patients with EF >45 but the difference was not significant (P-value >0.05). Conclusion: Patients who had high level of zinc had greater risk for mortality. Zn level was lower among patients with EF >45 but the difference was not significant and the least mean of zinc was among patients with left ventricular (LV) systolic dysfunction.
    Keywords Medicine (General) ; R5-920 ; Medicine ; R ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Subject code 610 ; 616
    Language English
    Publishing date 2014-01-01T00:00:00Z
    Publisher Pan Arab League of Continuous Medical Education
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  8. Article ; Online: Gut microbiota density influences host physiology and is shaped by host and microbial factors.

    Contijoch, Eduardo J / Britton, Graham J / Yang, Chao / Mogno, Ilaria / Li, Zhihua / Ng, Ruby / Llewellyn, Sean R / Hira, Sheela / Johnson, Crystal / Rabinowitz, Keren M / Barkan, Revital / Dotan, Iris / Hirten, Robert P / Fu, Shih-Chen / Luo, Yuying / Yang, Nancy / Luong, Tramy / Labrias, Philippe R / Lira, Sergio /
    Peter, Inga / Grinspan, Ari / Clemente, Jose C / Kosoy, Roman / Kim-Schulze, Seunghee / Qin, Xiaochen / Castillo, Anabella / Hurley, Amanda / Atreja, Ashish / Rogers, Jason / Fasihuddin, Farah / Saliaj, Merjona / Nolan, Amy / Reyes-Mercedes, Pamela / Rodriguez, Carina / Aly, Sarah / Santa-Cruz, Kenneth / Peters, Lauren / Suárez-Fariñas, Mayte / Huang, Ruiqi / Hao, Ke / Zhu, Jun / Zhang, Bin / Losic, Bojan / Irizar, Haritz / Song, Won-Min / Di Narzo, Antonio / Wang, Wenhui / Cohen, Benjamin L / DiMaio, Christopher / Greenwald, David / Itzkowitz, Steven / Lucas, Aimee / Marion, James / Maser, Elana / Ungaro, Ryan / Naymagon, Steven / Novak, Joshua / Shah, Brijen / Ullman, Thomas / Rubin, Peter / George, James / Legnani, Peter / Telesco, Shannon E / Friedman, Joshua R / Brodmerkel, Carrie / Plevy, Scott / Cho, Judy H / Colombel, Jean-Frederic / Schadt, Eric E / Argmann, Carmen / Dubinsky, Marla / Kasarskis, Andrew / Sands, Bruce / Faith, Jeremiah J

    eLife

    2019  Volume 8

    Abstract: To identify factors that regulate gut microbiota density and the impact of varied microbiota density on health, we assayed this fundamental ecosystem property in fecal samples across mammals, human disease, and therapeutic interventions. Physiologic ... ...

    Abstract To identify factors that regulate gut microbiota density and the impact of varied microbiota density on health, we assayed this fundamental ecosystem property in fecal samples across mammals, human disease, and therapeutic interventions. Physiologic features of the host (carrying capacity) and the fitness of the gut microbiota shape microbiota density. Therapeutic manipulation of microbiota density in mice altered host metabolic and immune homeostasis. In humans, gut microbiota density was reduced in Crohn's disease, ulcerative colitis, and ileal pouch-anal anastomosis. The gut microbiota in recurrent
    Editorial note: This article has been through an editorial process in which the authors decide how to respond to the issues raised during peer review. The Reviewing Editor's assessment is that all the issues have been addressed (see decision letter).
    MeSH term(s) Adiposity ; Adult ; Aged ; Aged, 80 and over ; Animals ; Clostridioides difficile ; Clostridium Infections/microbiology ; Crohn Disease/microbiology ; Fecal Microbiota Transplantation ; Female ; Gastrointestinal Microbiome ; Homeostasis ; Humans ; Ileum/microbiology ; Immune System ; Inflammatory Bowel Diseases ; Male ; Mice ; Mice, Inbred C57BL ; Microbiota ; Middle Aged ; Mucous Membrane/microbiology ; Phenotype ; RNA, Ribosomal, 16S/metabolism ; Species Specificity ; Young Adult
    Chemical Substances RNA, Ribosomal, 16S
    Language English
    Publishing date 2019-01-22
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2687154-3
    ISSN 2050-084X ; 2050-084X
    ISSN (online) 2050-084X
    ISSN 2050-084X
    DOI 10.7554/eLife.40553
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top