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  1. Article ; Online: Comparison of Caregiver and Provider Food Insecurity Screening Preferences Within a Health System.

    Alvis, Courtney E / Mosha, Maua / Amankwah, Ernest K / Hernandez, Raquel G / Morrison, John M

    Clinical pediatrics

    2023  Volume 63, Issue 5, Page(s) 650–658

    Abstract: Food insecurity is a public health concern associated with poor health. Evidence guiding how to best implement screening for food insecurity across a pediatric health care system is lacking. We performed a single-center, multi-department, cross-sectional ...

    Abstract Food insecurity is a public health concern associated with poor health. Evidence guiding how to best implement screening for food insecurity across a pediatric health care system is lacking. We performed a single-center, multi-department, cross-sectional study of caregivers and health care providers in outpatient and inpatient settings to describe the beliefs, barriers, preferences, and preferred food insecurity screening location. Most providers and caregivers underestimated the pervasiveness of food insecurity while acknowledging the benefit of screening. Caregivers are overall receptive to food insecurity screening and disagree with feelings of discomfort or shame when disclosing food insecurity status. Providers acknowledged perceived caregiver discomfort, lack of community food resources, and lack of a validated screening tool as barriers to screening. Both caregivers and providers identified the primary care setting as the preferred screening setting.
    MeSH term(s) Humans ; Food Insecurity ; Cross-Sectional Studies ; Caregivers/psychology ; Caregivers/statistics & numerical data ; Female ; Male ; Mass Screening/methods ; Mass Screening/statistics & numerical data ; Adult ; Child ; Attitude of Health Personnel ; Health Personnel/psychology ; Health Personnel/statistics & numerical data
    Language English
    Publishing date 2023-08-09
    Publishing country United States
    Document type Journal Article ; Comparative Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 207678-0
    ISSN 1938-2707 ; 0009-9228
    ISSN (online) 1938-2707
    ISSN 0009-9228
    DOI 10.1177/00099228231191926
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  2. Article ; Online: Heliox Prescribing Trends for Pediatric Critical Asthma.

    Lew, Alicia / Morrison, John M / K Amankwah, Ernest / Sochet, Anthony A

    Respiratory care

    2022  Volume 67, Issue 5, Page(s) 510–519

    Abstract: Background: Children with asthma exacerbations requiring pediatric ICU (PICU) admission, known as critical asthma (CA), are prescribed a variety of therapeutic interventions including heliox. Delivered invasively and noninvasively, heliox is employed to ...

    Abstract Background: Children with asthma exacerbations requiring pediatric ICU (PICU) admission, known as critical asthma (CA), are prescribed a variety of therapeutic interventions including heliox. Delivered invasively and noninvasively, heliox is employed to enhance deposition of aerosolized medications, improve obstructive pulmonary pathophysiology, and avoid complications associated with invasive mechanical ventilation. We used the Virtual Pediatric Systems database to update estimates of heliox prescription and explore for relationships between heliox and mechanical ventilation frequency and duration.
    Methods: We performed a retrospective cohort study using data from 97 PICUs among children 3-17 y of age admitted for CA from 2013-2019. The primary outcome was heliox prescribing rates and trends. Subgroup analyses assessed mechanical ventilation rates and duration by heliox exposure.
    Results: Of 43,238 subjects studied, 1,070 (2.5%) were prescribed heliox. Mean heliox prescribing rates fell from 4.11% in 2013 to 2.37% in 2019. Heliox use was greater from centers in the South (2.6%) and Midwest (3.3%) as compared to the West (1.6%) and Northeast United States (1.6%,
    Conclusions: Heliox as adjunctive therapy for children with CA is uncommon (2.5%) and not associated with mechanical ventilation or decreased mechanical ventilation duration in adjusted models. Updated estimates provided herein inform prospective controlled trial development to better define the role of heliox for CA.
    MeSH term(s) Asthma/drug therapy ; Child ; Helium/therapeutic use ; Humans ; Oxygen ; Prospective Studies ; Retrospective Studies
    Chemical Substances Helium (206GF3GB41) ; heliox (58933-55-4) ; Oxygen (S88TT14065)
    Language English
    Publishing date 2022-04-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603252-7
    ISSN 1943-3654 ; 0098-9142 ; 0020-1324
    ISSN (online) 1943-3654
    ISSN 0098-9142 ; 0020-1324
    DOI 10.4187/respcare.09385
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    Zs.B 2285: Show issues Location:
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  3. Article ; Online: Association between cumulative exposure to adverse childhood experiences and childhood obesity.

    Purswani, Pooja / Marsicek, Sarah M / Amankwah, Ernest K

    PloS one

    2020  Volume 15, Issue 9, Page(s) e0239940

    Abstract: Background: Exposure to adverse childhood experiences (ACEs) is associated with many childhood diseases and poor health outcomes in adulthood. However, the association with childhood obesity is inconsistent. We investigated the association between ... ...

    Abstract Background: Exposure to adverse childhood experiences (ACEs) is associated with many childhood diseases and poor health outcomes in adulthood. However, the association with childhood obesity is inconsistent. We investigated the association between reported cumulative ACE score and body mass index (BMI) in a large sample of patients at a single institution.
    Methods: This cross-sectional study included children aged 2-20 years that were screened in a general pediatrics clinic for ACEs utilizing the Center for Youth Wellness ACEs questionnaire between July 2017 and July 2018. Overall ACE score was categorized as 'no exposure' (score = 0), 'low exposure' (score = 1), and 'high exposure' (score≥ 2). BMI was categorized as overweight/obese (BMI percentile ≥ 85) or non-obese (BMI percentile < 85). The association between ACEs score and obesity was determined using univariate and multivariable logistic regression.
    Results: Of the 948 patients included in the study, 30% (n = 314) were overweight/obese and 53% (n = 504) had no ACE exposure, 19% (n = 179) had low ACE exposure, and 28% (n = 265) had high ACE exposure. High ACE exposure was associated with increased odds of obesity (OR = 1.47, 95%CI = 1.07-2.03, p = 0.026). However, after adjusting for age, race/ethnicity, insurance type, and birth weight, the association attenuated and was null (OR = 1.01, 95%CI = 0.70-1.46, p = 0.97).
    Conclusion: The study findings may suggest an association between ACE and childhood obesity. However, the association attenuated after adjusting for age, race/ethnicity, insurance type, and birth weight. Larger prospective studies are warranted to better understand the association.
    MeSH term(s) Adolescent ; Adverse Childhood Experiences/statistics & numerical data ; Child ; Child, Preschool ; Female ; Humans ; Male ; Pediatric Obesity/epidemiology ; Pediatric Obesity/psychology ; Socioeconomic Factors ; Young Adult
    Language English
    Publishing date 2020-09-29
    Publishing country United States
    Document type Journal Article
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0239940
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  4. Article ; Online: Enhancing Collaboration between Clinician-Researchers and Methodologists in Clinical Research.

    Amuah, Joseph / Mutasingwa, Donatus R / Amankwah, Ernest K

    The Journal of pediatrics

    2020  Volume 221S, Page(s) S58–S61

    MeSH term(s) Biomedical Research/organization & administration ; Communication ; Cooperative Behavior ; Data Analysis ; Data Collection ; Data Interpretation, Statistical ; Humans ; Organizational Culture ; Research Personnel
    Language English
    Publishing date 2020-06-16
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 3102-1
    ISSN 1097-6833 ; 0022-3476
    ISSN (online) 1097-6833
    ISSN 0022-3476
    DOI 10.1016/j.jpeds.2020.02.035
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  5. Article ; Online: Measuring the Validity and Reliability of the Vascular Access Complication Staging and Treatment Instrument in a Pediatric Population.

    Cline, Genieveve J / Pohlod, Virginia / Burger, Kristina J / Amankwah, Ernest K

    Journal of infusion nursing : the official publication of the Infusion Nurses Society

    2021  Volume 44, Issue 4, Page(s) 225–243

    Abstract: A multiphase study designed with Delphi and observational components was conducted to establish the preliminary validity and reliability of the 2018 Vascular Access Complication Staging and Treatment Instrument in pediatric and neonatal populations from ... ...

    Abstract A multiphase study designed with Delphi and observational components was conducted to establish the preliminary validity and reliability of the 2018 Vascular Access Complication Staging and Treatment Instrument in pediatric and neonatal populations from a single, free-standing academic children's hospital. The instrument uses objective measurement criterion to determine the severity of swelling and tissue damage to inform treatment decisions. The results of the study provided preliminary empirical evidence to support a pediatric and neonatal intravenous complication staging instrument to assess degree of swelling and severity of tissue injury. The study also offered preliminary evidence that the instrument was perceived by the nurses who participated in the study to be efficient and easy to use.
    MeSH term(s) Child ; Humans ; Infant, Newborn ; Pediatrics ; Reproducibility of Results ; Vascular Access Devices
    Language English
    Publishing date 2021-07-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2192558-6
    ISSN 1539-0667 ; 1533-1458
    ISSN (online) 1539-0667
    ISSN 1533-1458
    DOI 10.1097/NAN.0000000000000431
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    Zs.A 6128: Show issues Location:
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  6. Article ; Online: Heliox for Pediatric Critical Asthma: A Multicenter, Retrospective, Registry-Based Descriptive Study.

    Lew, Alicia / Morrison, John M / Amankwah, Ernest / Sochet, Anthony A

    Journal of intensive care medicine

    2021  Volume 37, Issue 6, Page(s) 776–783

    Abstract: Background: In cases of critical asthma (CA), heliox may be applied as an adjunctive rescue therapy to avoid invasive mechanical ventilation (MV), improve deposition of aerosolized medications, and enhance laminar airflow through obstructed airways. ... ...

    Abstract Background: In cases of critical asthma (CA), heliox may be applied as an adjunctive rescue therapy to avoid invasive mechanical ventilation (MV), improve deposition of aerosolized medications, and enhance laminar airflow through obstructed airways. Using the Pediatric Health Information System (PHIS) registry, we evaluate heliox prescribing and explored for differences in MV rates and hospital length of stay (LOS) among children with and without heliox exposure.
    Methods: We performed a retrospective cohort study using PHIS data from 42 pediatric intensive care units among children 5-17 years of age admitted for CA from 2010 through 2019. Primary outcomes were heliox prescribing rates and trends. Secondary outcomes were invasive MV rates and LOS assessed in a subgroup of children receiving ≥ 1 adjunctive intervention(s).
    Results: Of the 19,780 studied, heliox was prescribed in 12.5% and linearly declined from 16.1% in 2010 to 5.6% in 2019. The overall MV rate was 12.8% and was lower in subjects receiving heliox alone (4.9%) compared to heliox plus alternative adjunctive therapies [31.2%] or children receiving non-heliox adjunctive therapies [22.1%],
    Conclusions: In this multicenter retrospective study from 42 children's hospitals, heliox prescribing for CA declined over the last decade. Subjects receiving multiple adjunctive therapies more commonly required invasive MV perhaps indicating a greater severity of illness. At this time, prospective trials needed to identify the role of heliox for pediatric CA.
    MeSH term(s) Asthma/drug therapy ; Child ; Helium ; Humans ; Oxygen ; Prospective Studies ; Registries ; Retrospective Studies
    Chemical Substances Helium (206GF3GB41) ; heliox (58933-55-4) ; Oxygen (S88TT14065)
    Language English
    Publishing date 2021-06-22
    Publishing country United States
    Document type Journal Article ; Multicenter Study
    ZDB-ID 632828-3
    ISSN 1525-1489 ; 0885-0666
    ISSN (online) 1525-1489
    ISSN 0885-0666
    DOI 10.1177/08850666211026550
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    Zs.A 2158: Show issues Location:
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  7. Article ; Online: Prevalence of Gastroesophageal Reflux Disease in Infants With Congenital Muscular Torticollis: A Prospective Cohort Study.

    Bess, Laura K / Costa, Jessica / Nguygen, Anh Thy H / Amankwah, Ernest / Wilsey, Michael J

    Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association

    2022  Volume 34, Issue 2, Page(s) 180–183

    Abstract: Purpose: Clinical experience suggests that gastroesophageal reflux disease (GERD) occurs commonly in infants with congenital muscular torticollis (CMT). However, this is an understudied topic and prospective studies are absent. We determine the ... ...

    Abstract Purpose: Clinical experience suggests that gastroesophageal reflux disease (GERD) occurs commonly in infants with congenital muscular torticollis (CMT). However, this is an understudied topic and prospective studies are absent. We determine the prevalence of GERD in infants with CMT, comparing clinical characteristics between CMT infants with and without GERD, and identifying infants with potentially undiagnosed GERD.
    Methods: A prospective cohort study of 155 infants with CMT younger than 12 months with and without GERD was evaluated by pediatric physical therapists.
    Results: GERD prevalence was 30.3%, including 6 (3.9%) infants with undiagnosed GERD. Demographic and clinical characteristics were similar in CMT infants with and without GERD.
    Conclusions: This is the first prospective cohort study determining the prevalence of GERD in infants referred for evaluation of CMT. Further prospective studies are needed to determine whether early intervention and treatment of GERD improves outcomes in infants with CMT (see Supplemental Digital Content 1, available at: http://links.lww.com/PPT/A369).
    MeSH term(s) Child ; Gastroesophageal Reflux/diagnosis ; Gastroesophageal Reflux/epidemiology ; Humans ; Infant ; Prevalence ; Prospective Studies ; Torticollis/congenital
    Language English
    Publishing date 2022-04-06
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1036679-9
    ISSN 1538-005X ; 0898-5669
    ISSN (online) 1538-005X
    ISSN 0898-5669
    DOI 10.1097/PEP.0000000000000883
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    Zs.A 2712: Show issues Location:
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  8. Article ; Online: Hispanic Ethnicity and the Risk of Pediatric Leukemia Relapse.

    Amankwah, Ernest K / Hale, Greg A

    Clinical pediatrics

    2017  Volume 57, Issue 6, Page(s) 656–659

    Abstract: Limited knowledge currently exists on the disparity in pediatric leukemia relapse. This study compared the risk of pediatric leukemia relapse between Hispanic and non-Hispanic Whites. Study participants were children (<20 years) diagnosed with leukemia ... ...

    Abstract Limited knowledge currently exists on the disparity in pediatric leukemia relapse. This study compared the risk of pediatric leukemia relapse between Hispanic and non-Hispanic Whites. Study participants were children (<20 years) diagnosed with leukemia from January 2006 to December 2014 at the Johns Hopkins All Children's Hospital, St. Petersburg, Florida. Hazard ratios and 95% confidence intervals for relapse-free survival were calculated using adjusted Cox regression. The study included 35 Hispanic and 94 non-Hispanic Whites. Among patients <10 years old, there was a significantly higher risk of relapse in Hispanic compared to non-Hispanic Whites (hazard ratio = 6.19, 95% confidence interval = 1.15-33.27). No association was observed for patients aged ≥10 years nor all participants combined. Although the finding of this study may suggest that ethnic disparity in pediatric leukemia relapse may exist in younger children, our finding is limited by the small sample size from a single institution. Therefore, future larger multiinstitutional studies are warranted.
    MeSH term(s) Child ; Ethnic Groups ; Florida/epidemiology ; Hispanic Americans/statistics & numerical data ; Humans ; Leukemia/epidemiology ; Recurrence ; Risk
    Language English
    Publishing date 2017-09-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 207678-0
    ISSN 1938-2707 ; 0009-9228
    ISSN (online) 1938-2707
    ISSN 0009-9228
    DOI 10.1177/0009922817732147
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    Zs.A 454: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  9. Article ; Online: Effects of Cumulative Head Impact Exposure in Adolescent Male Contact and Collision Sport Student Athletes.

    Ransom, Danielle M / Ahumada, Luis / Amankwah, Ernest K / Katzenstein, Jennifer M / Goldenberg, Neil A / Bauer, Timothy A / Mularoni, P Patrick

    The Journal of head trauma rehabilitation

    2023  

    Abstract: Objective: This prospective cohort study aimed to investigate the association between head impact exposure (HIE) and neuropsychological sequelae in high school football and ice hockey players over 1 year.: Setting: Community sample.: Participants: ...

    Abstract Objective: This prospective cohort study aimed to investigate the association between head impact exposure (HIE) and neuropsychological sequelae in high school football and ice hockey players over 1 year.
    Setting: Community sample.
    Participants: A cohort of 52 adolescent American football and ice hockey players were enrolled in the study, with a final study sample of 35 included in analyses.
    Design: The study followed a prospective cohort design, with participants undergoing neuropsychological screening and accelerometer-based measurement of HIE over 1 season.
    Main measures: Changes in cognition, emotions, behavior, and reported symptoms were assessed using standardized neuropsychological tests and self-reported questionnaires.
    Results: Cumulative HIE was not consistently associated with changes in cognition, emotions, behavior, or reported symptoms. However, it was linked to an isolated measure of processing speed, showing inconsistent results based on the type of HIE. History of previous concussion was associated with worsened verbal memory recognition (ImPACT Verbal Memory) but not on a more robust measure of verbal memory (California Verbal Learning Test [CVLT]). Reported attention-deficit/hyperactivity disorder history predicted improved neurocognitive change scores. No associations were found between reported history of anxiety/depression or headaches/migraines and neuropsychological change scores.
    Conclusion: Overall, our findings do not support the hypothesis that greater HIE is associated with an increase in neuropsychological sequelae over time in adolescent football and ice hockey players. The results align with the existing literature, indicating that HIE over 1 season of youth sports is not consistently associated with significant neuropsychological changes. However, the study is limited by a small sample size, attrition over time, and the absence of performance validity testing for neurocognitive measures. Future studies with larger and more diverse samples, longer follow-up, and integration of advanced imaging and biomarkers are needed to comprehensively understand the relationship between HIE and neurobehavioral outcomes. Findings can inform guidelines for safe youth participation in contact sports while promoting the associated health and psychosocial benefits.
    Language English
    Publishing date 2023-10-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639221-0
    ISSN 1550-509X ; 0885-9701
    ISSN (online) 1550-509X
    ISSN 0885-9701
    DOI 10.1097/HTR.0000000000000915
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  10. Article ; Online: A Look Back at Healthy Lifestyle Behavioral Patterns among School-Age Children: Are We Neglecting Healthy Weight for Overweight Kids?

    Hernandez, Raquel G / Garcia, Janelle T / Amankwah, Ernest K

    Childhood obesity (Print)

    2019  Volume 15, Issue 4, Page(s) 271–279

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Body Mass Index ; Body Weight ; Child ; Cohort Studies ; Exercise ; Female ; Health Behavior ; Health Promotion/methods ; Healthy Lifestyle ; Humans ; Longitudinal Studies ; Male ; Meals ; Pediatric Obesity/therapy ; Screen Time ; Sleep
    Language English
    Publishing date 2019-03-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2639910-6
    ISSN 2153-2176 ; 2153-2168
    ISSN (online) 2153-2176
    ISSN 2153-2168
    DOI 10.1089/chi.2018.0334
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