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  1. Article ; Online: Improving health literacy through group antenatal care: results from a cluster randomized controlled trial in Ghana.

    Lori, Jody R / Kukula, Vida Ami / Liu, Liya / Apetorgbor, Veronica E A / Ghosh, Bidisha / Awini, Elizabeth / Lockhart, Nancy / Amankwah, Georgina / Zielinski, Ruth / Moyer, Cheryl A / Williams, John

    BMC pregnancy and childbirth

    2024  Volume 24, Issue 1, Page(s) 37

    Abstract: Background: Although the majority of Ghanaian women receive antenatal care (ANC), many exhibit low health literacy by misinterpreting and incorrectly operationalizing ANC messages, leading to poor maternal and newborn health outcomes. Prior research in ... ...

    Abstract Background: Although the majority of Ghanaian women receive antenatal care (ANC), many exhibit low health literacy by misinterpreting and incorrectly operationalizing ANC messages, leading to poor maternal and newborn health outcomes. Prior research in low-resource settings has found group antenatal care (G-ANC) feasible for women and providers. This study aims to determine the effect of G-ANC on increasing maternal health literacy. We hypothesized that pregnant women randomized into G-ANC would exhibit a greater increase in maternal health literacy than women in routine, individual ANC.
    Methods: A 5-year cluster randomized controlled trial was conducted in 14 rural and peri-urban health facilities in the Eastern Region of Ghana. Facilities were paired based on patient volume and average gestational age at ANC enrollment and then randomized into intervention (G-ANC) vs. control (routine, individual ANC); 1761 pregnant women were recruited. Data collection occurred at baseline (T0) and post-birth (T2) using the Maternal Health Literacy scale, a 12-item composite scale to assess maternal health literacy. Logistic regression compared changes in health literacy from T0 to T2.
    Results: Overall, women in both the intervention and control groups improved their health literacy scores over time (p < 0.0001). Women in the intervention group scored significantly higher on 3 individual items and on overall composite scores (p < 0.0001) and were more likely to attend 8 or more ANC visits.
    Conclusion: While health literacy scores improved for all women attending ANC, women randomized into G-ANC exhibited greater improvement in overall health literacy post-birth compared to those receiving routine individual care. Life-saving information provided during ANC must be presented in an understandable format to prevent women and newborns from dying of preventable causes.
    Trial registry: Ethical approval for the study was obtained from the Institutional Review Boards of the University of Michigan (HUM#00161464) and the Ghana Health Service (GHS-ERC: 016/04/19).
    MeSH term(s) Infant, Newborn ; Pregnancy ; Female ; Humans ; Health Literacy ; Prenatal Care ; Ghana ; Data Collection ; Family
    Language English
    Publishing date 2024-01-05
    Publishing country England
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 2059869-5
    ISSN 1471-2393 ; 1471-2393
    ISSN (online) 1471-2393
    ISSN 1471-2393
    DOI 10.1186/s12884-023-06224-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Sexual behaviours and their associated factors among young people in the Dodowa Health and Demographic Surveillance Site (DHDSS) in Ghana.

    Agyekum, Mary P / Agyekum, Enoch O / Adjei, Alexander / Asare, Kwabena / Akpakli, David E / Asiamah, Sabina / Tsey, Irene / Amankwah, Georgina / Manyeh, Alfred K / Williams, John E O / Ross, David A

    Ghana medical journal

    2024  Volume 56, Issue 3 Suppl, Page(s) 43–50

    Abstract: Objective: This paper describes sexual behaviours and their associated factors among young people.: Design: The study design is cross-sectional.: Setting: Dodowa Health and Demographic Surveillance Site (DHDSS) in Ghana's Shai-Osudoku and Ningo ... ...

    Abstract Objective: This paper describes sexual behaviours and their associated factors among young people.
    Design: The study design is cross-sectional.
    Setting: Dodowa Health and Demographic Surveillance Site (DHDSS) in Ghana's Shai-Osudoku and Ningo Prampram districts.
    Participants: Young people aged 10 to 24 years, median age 17 years.
    Outcome measures: Self-reported to have ever had sex, non-use of a condom at last sex, and ever been pregnant or gotten someone pregnant.
    Results: Of the 1689 young people; 42% reported having ever had sex, not using a condom at last sexual activity (64%), and ever been pregnant or gotten someone pregnant (41%). The proportion of non-use of condoms at last sex was high across all age groups but was highest (93%) in a small proportion of 10 to 14-year-olds who have ever had sex. Higher proportions of females than males; were reported to have ever had sex (46%), not using a condom at their last sex (66%) and ever been pregnant or getting someone pregnant (56%). Age group (20 to 24), females, primary or junior high school, living alone and lower household socio-economic status were risk factors associated with all three outcome measures.
    Conclusion: Risky sexual behaviour is high among young people in the Dodowa HDSS. Therefore, interventions that promote safer sexual practices and help young people make timely decisions on their sexual and reproductive health care needs are required.
    Funding: No funding was obtained for this paper.
    MeSH term(s) Male ; Pregnancy ; Female ; Humans ; Adolescent ; Cross-Sectional Studies ; Ghana ; Sexual Behavior ; Condoms ; Demography
    Language English
    Publishing date 2024-01-24
    Publishing country Ghana
    Document type Journal Article
    ZDB-ID 2259233-7
    ISSN 2616-163X ; 2616-163X
    ISSN (online) 2616-163X
    ISSN 2616-163X
    DOI 10.4314/gmj.v56i3s.6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Group Antenatal Care in Ghana: Protocol for a Cluster Randomized Controlled Trial.

    Lori, Jody R / Williams, John E O / Kukula, Vida A / Apetorgbor, Veronica E A / Awini, Elizabeth A / Amankwah, Georgina / Zielinski, Ruth / Lockhart, Nancy / James, Katherine H / Moyer, Cheryl A

    JMIR research protocols

    2022  Volume 11, Issue 9, Page(s) e40828

    Abstract: Background: While group antenatal care (ANC) has been delivered and studied in high-income countries for over a decade, it has only recently been introduced as an alternative to individual care in sub-Saharan Africa. Although the experimental design of ... ...

    Abstract Background: While group antenatal care (ANC) has been delivered and studied in high-income countries for over a decade, it has only recently been introduced as an alternative to individual care in sub-Saharan Africa. Although the experimental design of the studies from high-resource countries have been scientifically rigorous, findings cannot be generalized to low-resource countries with low literacy rates and high rates of maternal and newborn morbidity and mortality. The Group Antenatal Care Delivery Project (GRAND) is a collaboration between the University of Michigan in the United States and the Dodowa Health Research Centre in Ghana. GRAND is a 5-year, cluster randomized controlled trial (RCT). Our intervention-group ANC-consists of grouping women by similar gestational ages of pregnancy into small groups at the first ANC visit. They then meet with the same group and the same midwife at the recommended intervals for care.
    Objective: This study aims to improve health literacy, increase birth preparedness and complication readiness, and optimize maternal and newborn outcomes among women attending ANC at seven rural health facilities in the Eastern Region of Ghana.
    Methods: Quantitative data will be collected at four time points using a secure web application for data collection and a database management tool. Data will be analyzed on an intention-to-treat basis to test the differences between the two arms: women randomized to group-based ANC and women randomized to routine individual ANC. We will conduct a process evaluation concurrently to identify and document patient, provider, and system barriers and facilitators to program implementation.
    Results: The study was funded in September 2018. Recruitment and enrollment of participants and data collection started in July 2019. In November 2021, we completed participant enrollment in the study (n=1761), and we completed data collection at the third trimester in May 2022 (n=1284). Data collection at the additional three time points is ongoing: 6 weeks postpartum, 6 months postpartum, and 1 year postpartum.
    Conclusions: This study is significant and timely because it is among the first RCTs to be conducted to examine the effects of group ANC among low-literacy and nonliterate participants. Our findings have the potential to impact how clinical care is delivered to low-literacy populations, both globally and domestically, to improve maternal and newborn outcomes.
    Trial registration: ClinicalTrials.gov NCT04033003; https://clinicaltrials.gov/ct2/show/NCT04033003.
    International registered report identifier (irrid): DERR1-10.2196/40828.
    Language English
    Publishing date 2022-09-09
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 2719222-2
    ISSN 1929-0748
    ISSN 1929-0748
    DOI 10.2196/40828
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Community-based antibiotic access and use in six low-income and middle-income countries: a mixed-method approach.

    Do, Nga T T / Vu, Huong T L / Nguyen, Chuc T K / Punpuing, Sureeporn / Khan, Wasif Ali / Gyapong, Margaret / Asante, Kwaku Poku / Munguambe, Khatia / Gómez-Olivé, F Xavier / John-Langba, Johannes / Tran, Toan K / Sunpuwan, Malee / Sevene, Esperanca / Nguyen, Hanh H / Ho, Phuc D / Matin, Mohammad Abdul / Ahmed, Sabeena / Karim, Mohammad Mahbubul / Cambaco, Olga /
    Afari-Asiedu, Samuel / Boamah-Kaali, Ellen / Abdulai, Martha Ali / Williams, John / Asiamah, Sabina / Amankwah, Georgina / Agyekum, Mary Pomaa / Wagner, Fezile / Ariana, Proochista / Sigauque, Betuel / Tollman, Stephen / van Doorn, H Rogier / Sankoh, Osman / Kinsman, John / Wertheim, Heiman F L

    The Lancet. Global health

    2021  Volume 9, Issue 5, Page(s) e610–e619

    Abstract: Background: Antimicrobial misuse is common in low-income and middle-income countries (LMICs), and this practice is a driver of antibiotic resistance. We compared community-based antibiotic access and use practices across communities in LMICs to identify ...

    Abstract Background: Antimicrobial misuse is common in low-income and middle-income countries (LMICs), and this practice is a driver of antibiotic resistance. We compared community-based antibiotic access and use practices across communities in LMICs to identify contextually specific targets for interventions to improve antibiotic use practices.
    Methods: We did quantitative and qualitative assessments of antibiotic access and use in six LMICs across Africa (Mozambique, Ghana, and South Africa) and Asia (Bangladesh, Vietnam, and Thailand) over a 2·5-year study period (July 1, 2016-Dec 31, 2018). We did quantitative assessments of community antibiotic access and use through supplier mapping, customer exit interviews, and household surveys. These quantitative assessments were triangulated with qualitative drug supplier and consumer interviews and discussions.
    Findings: Vietnam and Bangladesh had the largest proportions of non-licensed antibiotic dispensing points. For mild illness, drug stores were the most common point of contact when seeking antibiotics in most countries, except South Africa and Mozambique, where public facilities were most common. Self-medication with antibiotics was found to be widespread in Vietnam (55·2% of antibiotics dispensed without prescription), Bangladesh (45·7%), and Ghana (36·1%), but less so in Mozambique (8·0%), South Africa (1·2%), and Thailand (3·9%). Self-medication was considered to be less time consuming, cheaper, and overall, more convenient than accessing them through health-care facilities. Factors determining where treatment was sought often involved relevant policies, trust in the supplier and the drug, disease severity, and whether the antibiotic was intended for a child. Confusion regarding how to identify oral antibiotics was revealed in both Africa and Asia.
    Interpretation: Contextual complexities and differences between countries with different incomes, policy frameworks, and cultural norms were revealed. These contextual differences render a single strategy inadequate and instead necessitate context-tailored, integrated intervention packages to improve antibiotic use in LMICs as part of global efforts to combat antibiotic resistance.
    Funding: Wellcome Trust and Volkswagen Foundation.
    MeSH term(s) Africa ; Anti-Bacterial Agents/administration & dosage ; Asia ; Bangladesh ; Developing Countries ; Drug Misuse/statistics & numerical data ; Evaluation Studies as Topic ; Female ; Ghana ; Health Knowledge, Attitudes, Practice ; Health Services Accessibility/statistics & numerical data ; Humans ; Male ; Mozambique ; Poverty ; Qualitative Research ; Residence Characteristics ; South Africa ; Surveys and Questionnaires ; Thailand ; Vietnam
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2021-03-10
    Publishing country England
    Document type Evaluation Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2723488-5
    ISSN 2214-109X ; 2214-109X
    ISSN (online) 2214-109X
    ISSN 2214-109X
    DOI 10.1016/S2214-109X(21)00024-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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