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  1. Article ; Online: Integrated Treatment of Breast Cancer-related Lymphedema: A Descriptive Review of the State of the Art.

    Marchica, Paolo / D'Arpa, Salvatore / Magno, Stefano / Rossi, Cristina / Forcina, Luana / Capizzi, Vita / Oieni, Sebastiano / Amato, Carmela / Piazza, Dario / Gebbia, Vittorio

    Anticancer research

    2021  Volume 41, Issue 7, Page(s) 3233–3246

    Abstract: Background/aim: Upper limb breast cancer-related lymphedema (BCRL) is a chronic and severe condition affecting a significant percentage of breast cancer survivors. Even though its physiopathology is well-known, there is no worldwide consensus on BCRL ... ...

    Abstract Background/aim: Upper limb breast cancer-related lymphedema (BCRL) is a chronic and severe condition affecting a significant percentage of breast cancer survivors. Even though its physiopathology is well-known, there is no worldwide consensus on BCRL evaluation and a gold-standard treatment. This narrative review aims at providing a brief descriptive overview with regard to BCRL treatment modalities.
    Materials and methods: We conducted a literature search within the PubMed database, and 33 articles out of 56 were selected, including reviews, systematic reviews, and meta-analyses aiming find the most updated evidence regarding BCRL treatment modalities.
    Results: Physical exercise (aerobic exercise, resistance exercise, aquatic therapy), bandages, and intermittent pneumatic compression were shown to be most effective in BCRL patients, in terms of swelling reduction in the acute-intensive phase. Furthermore, physical exercise was beneficial also as a maintenance tool. Manual lymphatic drainage demonstrated efficacy in preventing secondary lymphedema if applied immediately after breast cancer surgery or in early phases of BCRL or as a maintenance tool. Complementary procedures such as acupuncture, reflexology, yoga and photo-biomodulation therapy did not show conclusive results in BCRL treatment. Surgery was shown effective in managing symptoms (liposuction), preventing (lymphaticovenular anastomosis) and treating BCRL (vascularized lymph node transfer).
    Conclusion: BCRL is still a challenging condition either for breast cancer survivors and clinicians, deeply impacting patient functioning and quality of life. Due to the lack of globally accepted criteria in evaluating BCRL, to date a gold standard treatment for this widespread issue is still needed.
    Language English
    Publishing date 2021-07-05
    Publishing country Greece
    Document type Journal Article ; Review
    ZDB-ID 604549-2
    ISSN 1791-7530 ; 0250-7005
    ISSN (online) 1791-7530
    ISSN 0250-7005
    DOI 10.21873/anticanres.15109
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1642: Show issues Location:
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  2. Article ; Online: Virtual Multidisciplinary Tumor Boards: A Narrative Review Focused on Lung Cancer.

    Gebbia, Vittorio / Guarini, Aurelia / Piazza, Dario / Bertani, Alessandro / Spada, Massimiliano / Verderame, Francesco / Sergi, Concetta / Potenza, Enrico / Fazio, Ivan / Blasi, Livio / La Sala, Alba / Mortillaro, Gianluca / Roz, Elena / Marchese, Roberto / Chiarenza, Maurizio / Soto-Parra, Hector / Valerio, Maria Rosaria / Agneta, Giuseppe / Amato, Carmela /
    Lipari, Helga / Baldari, Sergio / Ferraù, Francesco / Di Grazia, Alfio / Mancuso, Gianfranco / Rizzo, Sergio / Firenze, Alberto

    Pulmonary therapy

    2021  Volume 7, Issue 2, Page(s) 295–308

    Abstract: To date, the virtual multidisciplinary tumor boards (vMTBs) are increasingly used to achieve high-quality treatment recommendations across health-care regions, which expands and develops the local MTB team to a regional or national expert network. This ... ...

    Abstract To date, the virtual multidisciplinary tumor boards (vMTBs) are increasingly used to achieve high-quality treatment recommendations across health-care regions, which expands and develops the local MTB team to a regional or national expert network. This review describes the process of lung cancer-specific MTBs and the transition process from face-to-face tumor boards to virtual ones. The review also focuses on the project organization's description, advantages, and disadvantages. Semi-structured interviews identified five major themes for MTBs: current practice, attitudes, enablers, barriers, and benefits for the MTB. MTB teams exhibited positive responses to modeled data feedback. Virtualization reduces time spent for travel, allowing easier and timely patient discussions. This process requires a secure web platform to assure the respect of patients' privacy and presents the same unanswered problems. The implementation of vMTB also permits the implementation of networks especially in areas with geographical barriers facilitating interaction between large referral cancer centers and tertiary or community hospitals as well as easier access to clinical trial opportunities. Studies aimed to improve preparations, structure, and conduct of MTBs, research methods to monitor their performance, teamwork, and outcomes are also outlined in this article. Analysis of literature shows that MTB participants discuss 5-8 cases per meeting and that the use of a vMTB for lung cancer and in particular stage III NSCLC and complex stage IV cases is widely accepted by most health professionals. Despite still-existing gaps, overall vMTB represents a unique opportunity to optimize patient management in a patient-centered approach.
    Language English
    Publishing date 2021-06-04
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2364-1746
    ISSN (online) 2364-1746
    DOI 10.1007/s41030-021-00163-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Validity of needle core biopsy in the histological characterisation of mammary lesions.

    Cipolla, Calogero / Fricano, Salvatore / Vieni, Salvatore / Amato, Carmela / Napoli, Liborio / Graceffa, Giuseppa / Latteri, Stefania / Latteri, Mario Adelfio

    Breast (Edinburgh, Scotland)

    2006  Volume 15, Issue 1, Page(s) 76–80

    Abstract: Over the last few years, there has been an enormous increase in the use of needle core biopsy (CB) for the histopathological characterisation of suspect lesions of the breast. The aim of this study was to verify the diagnostic reliability of CB by ... ...

    Abstract Over the last few years, there has been an enormous increase in the use of needle core biopsy (CB) for the histopathological characterisation of suspect lesions of the breast. The aim of this study was to verify the diagnostic reliability of CB by comparing the histological results obtained with the use of this technique with those obtained from the whole of the surgically resected specimen. We studied 198 out of 426 patients with clinically and/or radiologically suspect breast lesions. We found correspondence between the histological examination of the whole of the excised specimen and that of the CB in 94.9% of the cases of infiltrating carcinoma and in 71.4% of those involving ductal carcinomas in situ. The predictive value of CB was 98.9%, sensitivity was 96.1% and specificity 93.3%. These results confirmed that CB is an extremely reliable diagnostic tool in the definition of breast lesions.
    MeSH term(s) Biopsy, Needle ; Breast Neoplasms/diagnosis ; Breast Neoplasms/pathology ; Breast Neoplasms/surgery ; Carcinoma, Ductal, Breast/diagnosis ; Carcinoma, Ductal, Breast/pathology ; Carcinoma, Ductal, Breast/surgery ; Carcinoma, Intraductal, Noninfiltrating/diagnosis ; Carcinoma, Intraductal, Noninfiltrating/pathology ; Carcinoma, Intraductal, Noninfiltrating/surgery ; Female ; Humans ; Reproducibility of Results ; Retrospective Studies ; Sensitivity and Specificity
    Language English
    Publishing date 2006-02
    Publishing country Netherlands
    Document type Comparative Study ; Journal Article ; Validation Studies
    ZDB-ID 1143210-x
    ISSN 1532-3080 ; 0960-9776
    ISSN (online) 1532-3080
    ISSN 0960-9776
    DOI 10.1016/j.breast.2005.01.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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    Zs.MO 588: Show issues

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  4. Article: Validità dello studio del linfonodo sentinella nel trattamento del carcinoma della mammella.

    Vieni, Salvatore / Cipolla, Calogero / Fricano, Salvatore / Amato, Carmela / Graceffa, Giuseppa / Sandonato, Luigi / Prinzi, Gabriele / Latteri, Stefania / Latteri, Mario Adelfio

    Chirurgia italiana

    2004  Volume 56, Issue 2, Page(s) 215–222

    Abstract: Since it was introduced in the 1990s, axillary sentinel lymph-node biopsy has been rapidly and widely adopted to avoid complete axillary dissection (though this is still the standard procedure). The aims of the study were two-fold: (i) to determine the ... ...

    Title translation Validity of the study of sentinel lymph nodes in the treatment of breast carcinoma.
    Abstract Since it was introduced in the 1990s, axillary sentinel lymph-node biopsy has been rapidly and widely adopted to avoid complete axillary dissection (though this is still the standard procedure). The aims of the study were two-fold: (i) to determine the value of different techniques of sentinel lymph-node identification and (ii) to verify the predictive value of such procedures through histological examination of the sentinel lymph node and axillary dissection in the same patients. Both sentinel lymph-node biopsy and axillary dissection were performed in 230 patients with T1 and T2 (< 3 cm) carcinoma of the breast. Preoperative lymphoscintigraphy was able to identify the sentinel lymph node in 97.4% of cases, but, with an intraoperative hand-held probe, it was possible to find the sentinel lymph node in 98.2% of cases (226/230 patients). The sentinel lymph node was metastatic in 49.1% of cases (111/226 patients) and negative in 50.9% (115/226). The incidence of false-negative cases was 2.6% (2/115 patients). The predictive value of the sentinel lymph node was 98.7%. Finally, lymph-mode mapping is possible is a very high percentage of patients and therefore it is always advisable to use all three methods of identification together. The diagnostic reliability of sentinel lymph-node status is equally high. At present there no studies are available with a long-term follow-up to confirm these findings, and therefore axillary dissection is still the standard surgical treatment for breast cancer.
    MeSH term(s) Adult ; Aged ; Breast Neoplasms/pathology ; Breast Neoplasms/surgery ; Carcinoma/pathology ; Carcinoma/surgery ; Female ; Humans ; Middle Aged ; Predictive Value of Tests ; Prospective Studies ; Reproducibility of Results ; Sentinel Lymph Node Biopsy
    Language Italian
    Publishing date 2004-03
    Publishing country Italy
    Document type English Abstract ; Journal Article ; Validation Studies
    ZDB-ID 603591-7
    ISSN 0009-4773
    ISSN 0009-4773
    Database MEDical Literature Analysis and Retrieval System OnLINE

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