LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 10

Search options

  1. Article: Nurses job satisfaction identified by personal preferences and perceived saturation divergence: a comparative cross-sectional study in Czech hospitals between 2011 and 2021.

    Vevoda, Jiri / Navratilova, Daniela / Machaczka, Ondrej / Ambroz, Petr / Vevodova, Sarka / Tomietto, Marco

    BMC nursing

    2023  Volume 22, Issue 1, Page(s) 422

    Abstract: Background: The perception of the quality of care provided by the medical institution to patients is directly affected by the job satisfaction of nurses. The feeling of job satisfaction is caused besides other things by the subjective expectations of ... ...

    Abstract Background: The perception of the quality of care provided by the medical institution to patients is directly affected by the job satisfaction of nurses. The feeling of job satisfaction is caused besides other things by the subjective expectations of employees about what their work should provide them with in return. The aim of the study is to evaluate and compare job satisfaction of hospital nurses in the Czech Republic in 2011 and 2021 by identifying differences between their personal preferences and perceived saturation.
    Methods: The respondents are hospital nurses in the Czech Republic in 2011 and 2021. A developed questionnaire was used to determine the job satisfaction factors. The order of factors of personal preferences, perceived saturation and differences between them was compiled. For evaluation was used the Euclidean distance model that enables to capture the order and determine the significance given by the distance in which the factors are located.
    Results: At the top of personal preferences of hospital nurses, the factors salary and patient care are in the first two places with a similar distance. The salary factor is the most preferred by hospital nurses in both evaluated periods, and at the same time there is the greatest discrepancy between personal preferences and perceived saturation. By contrast, image of profession and working conditions were sufficiently saturated by the employer in both periods, but nurses do not significantly prefer these factors.
    Conclusions: The salary and patient care (i.e. the mission of the nurse's work itself) are at the top of personal preferences of hospital nurses, with an exclusive position among other factors. We consider it important that the hospital management emphasizes them in the management of hospital nurses. At the same time, the patient care is perceived by the hospital nurses as one of the most saturated factors - in contrast to salary, which is located at the complete opposite pole as the least saturated factor and therefore emerges from the mutual comparison as the factor with the greatest degree of divergence. The stated conclusions are valid for both compared periods. New method of data evaluation was successfully tested.
    Language English
    Publishing date 2023-11-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 2091496-9
    ISSN 1472-6955
    ISSN 1472-6955
    DOI 10.1186/s12912-023-01586-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Risk Factors for Alzheimer's Disease: An Epidemiological Study.

    Janoutová, Jana / Kovalová, Martina / Machaczka, Ondřej / Ambroz, Petr / Zatloukalová, Anna / Němček, Kateřina / Janout, Vladimír

    Current Alzheimer research

    2021  Volume 18, Issue 5, Page(s) 372–379

    Abstract: Introduction: Dementia becomes a major public health challenge in both the Czech Republic and worldwide. The most common form of dementia is Alzheimer's disease (AD).: Objective: We conducted two successive epidemiological projects in 2012-2015 and ... ...

    Abstract Introduction: Dementia becomes a major public health challenge in both the Czech Republic and worldwide. The most common form of dementia is Alzheimer's disease (AD).
    Objective: We conducted two successive epidemiological projects in 2012-2015 and 2016-2019. Their aim was to study the effect of selected potential genetic, vascular and psychosocial risk factors on the development of AD by comparing their frequencies in AD patients and controls.
    Methods: Epidemiological case-control studies were conducted. In total, data from 2106 participants (1096 cases, 1010 controls) were analyzed.
    Results: Three times more females than males suffered from AD. The highest proportion of cases were those with primary education, unlike controls. There were statistically significantly more manual workers among cases than among controls. Of selected vascular risk factors, coronary heart disease was found to be statistically significantly more frequent in cases than in controls. The onset of hypertension and diabetes mellitus was earlier in controls than in cases. As for hobbies and interests, there were statistically significant differences in physical activity, reading and solving crosswords between the groups, with these activities being more common in controls.
    Conclusion: The prevalence of chronic neurodegenerative diseases, in particular AD, is currently increasing. Given the aging of the population, these conditions may be expected to rise in prevalence. Potential risk of AD needs to be studied, analyzed and confirmed; a detailed knowledge of the risks of AD and early detection of the pathology may therefore be very beneficial for prevention and early treatment of this condition.
    MeSH term(s) Aged ; Aging/physiology ; Alzheimer Disease/epidemiology ; Alzheimer Disease/genetics ; Case-Control Studies ; Coronary Disease/epidemiology ; Czech Republic/epidemiology ; Epidemiologic Studies ; Female ; Humans ; Male ; Prevalence ; Risk Factors
    Language English
    Publishing date 2021-08-19
    Publishing country United Arab Emirates
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2205170-3
    ISSN 1875-5828 ; 1567-2050
    ISSN (online) 1875-5828
    ISSN 1567-2050
    DOI 10.2174/1567205018666210820124135
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Neuropsychological tests and prediction of dementia in association with the degree of carotid stenosis.

    Machaczka, Ondrej / Skoloudik, David / Janoutova, Jana / Roubec, Martin / Reiterova, Eva / Kovalova, Martina / Zatloukalova, Anna / Ambroz, Petr / Janout, Vladimir

    Journal of applied biomedicine

    2022  Volume 20, Issue 4, Page(s) 115–123

    Abstract: This study constitutes a cross sectional analysis of the association between cognitive impairment defined by neuropsychological tests and carotid stenosis. The main objective was to compare the results of the Mini-Mental State Examination (MMSE) and ... ...

    Abstract This study constitutes a cross sectional analysis of the association between cognitive impairment defined by neuropsychological tests and carotid stenosis. The main objective was to compare the results of the Mini-Mental State Examination (MMSE) and Addenbrooke's Cognitive Examination-Revised (ACE-R) with regard to the degree of carotid stenosis. The sample comprised 744 patients who underwent a carotid duplex ultrasound and cognitive function testing (by ACE-R and MMSE). A multivariable analysis of potential confounding factors was completed. The significance of the different number of positive (MMSE ≤ 27, ACE-R ≤ 88) and negative (MMSE ≥ 28, ACE-R ≥ 89) results of the neuropsychological tests was analysed with regard to the degree of carotid stenosis (50-99%). Neuropsychological test results were also compared between carotid stenosis of 50-69%, 70-89%, and 90-99%. For both the MMSE and ACE-R, a difference was observed between positive and negative test results when higher degrees of stenosis were present. However, for the ACE-R only, more severe stenosis (80-89%, 90-99%) was predominantly associated with positive test results (p-value < 0.017). The same dependence for ACE-R (although not statistically significant) was observed in the group of patients without an ischemic stroke (confounding factor). In the case of the MMSE and more severe stenosis, negative results predominated, regardless of the confounding factor. There were no statistically significant differences in test results between carotid stenosis of 50-69%, 70-89%, and 90-99%. The results suggest that for assessing the early risk of cognitive impairment in patients with carotid atherosclerosis, the ACE-R appears more suitable than the MMSE.
    MeSH term(s) Humans ; Carotid Stenosis/diagnosis ; Carotid Stenosis/diagnostic imaging ; Constriction, Pathologic ; Cross-Sectional Studies ; Neuropsychological Tests ; Dementia/diagnosis ; Dementia/etiology ; Dementia/psychology
    Language English
    Publishing date 2022-12-15
    Publishing country Poland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2171142-2
    ISSN 1214-0287 ; 1214-0287
    ISSN (online) 1214-0287
    ISSN 1214-0287
    DOI 10.32725/jab.2022.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article: The relationship between atherosclerosis and dementia.

    Janoutová, Jana / Machaczka, Ondřej / Kovalová, Martina / Zatloukalová, Anna / Ambroz, Petr / Koutná, Veronika / Mrázková, Eva / Bar, Michal / Roubec, Martin / Bártová, Petra / Novobilský, Richard / Sabela, Martin / Kušnierová, Pavlína / Stejskal, David / Faldynová, Lucie / Walczysková, Sylwia / Vališ, Martin / Školoudík, Lukáš / Šolínová, Petra /
    Školoudík, David / Janout, Vladimír

    Central European journal of public health

    2024  Volume 32, Issue 1, Page(s) 9–15

    Abstract: Objective: The main objective is to confirm a hypothesis that atherosclerosis, through various mechanisms, considerably influences cognitive impairment and significantly increases the risk for developing dementia. Complete sample should be 920 ... ...

    Abstract Objective: The main objective is to confirm a hypothesis that atherosclerosis, through various mechanisms, considerably influences cognitive impairment and significantly increases the risk for developing dementia. Complete sample should be 920 individuals. The present study aimed to analyse epidemiological data from a questionnaire survey.
    Methods: The work was carried out in the form of an epidemiological case control study. Subjects are enrolled in the study based on results of the following examinations carried out in neurology departments and outpatient centres during the project NU20-09-00119 from 2020 to 2023. Respondents were divided into four research groups according to the results of clinical examination for the presence of atherosclerosis and dementia. The survey was mainly concerned with risk factors for both atherosclerosis and dementia. It contained questions on lifestyle factors, cardiovascular risk factors, leisure activities, and hobbies.
    Results: Analysis of the as yet incomplete sample of 877 subjects has yielded the following selected results: on average, 16% of subjects without dementia had primary education while the proportion was 45.2% in the group with both dementia and atherosclerosis. Subjects with dementia did mainly physical work. Low physical activity was more frequently noted in dementia groups (Group 2 - 54.4% and Group 3 - 47.2%) than in subjects without dementia (Group 1 - 19.6% and Group 4 - 25.8%). Coronary heart disease was more frequently reported by dementia patients (33.95%) than those without dementia (16.05%).
    Conclusion: Cognitively impaired individuals, in particular those with vascular cognitive impairment, have poorer quality of life and shorter survival. Risk factors contributing to such impairment are similar to those for ischaemic or haemorrhagic stroke. It may be concluded that most of the analysed risk factors play a role in the development of both atherosclerosis and dementia.
    MeSH term(s) Humans ; Female ; Dementia/epidemiology ; Male ; Atherosclerosis/epidemiology ; Aged ; Risk Factors ; Case-Control Studies ; Middle Aged ; Surveys and Questionnaires ; Aged, 80 and over ; Life Style
    Language English
    Publishing date 2024-04-26
    Publishing country Czech Republic
    Document type Journal Article
    ZDB-ID 1176053-9
    ISSN 1803-1048 ; 1210-7778 ; 0022-1732
    ISSN (online) 1803-1048
    ISSN 1210-7778 ; 0022-1732
    DOI 10.21101/cejph.a7848
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article: Epidemiology and risk factors of schizophrenia.

    Janoutová, Jana / Janácková, Petra / Serý, Omar / Zeman, Tomás / Ambroz, Petr / Kovalová, Martina / Varechová, Katerina / Hosák, Ladislav / Jirík, Vitezslav / Janout, Vladimír

    Neuro endocrinology letters

    2016  Volume 37, Issue 1, Page(s) 1–8

    Abstract: Schizophrenia is a severe mental disorder that affects approximately one percent of the general population. The pathogenesis of schizophrenia is influenced by many risk factors, both environmental and genetic. The environmental factors include the date ... ...

    Abstract Schizophrenia is a severe mental disorder that affects approximately one percent of the general population. The pathogenesis of schizophrenia is influenced by many risk factors, both environmental and genetic. The environmental factors include the date of birth, place of birth and seasonal effects, infectious diseases, complications during pregnancy and delivery, substance abuse and stress. At the present time, in addition to environmental factors, genetic factors are assumed to play a role in the development of the schizophrenia. The heritability of schizo- phrenia is up to 80%. If one parent suffers from the condition, the probability that it will be passed down to the offspring is 13%. If it is present in both parents, the risk is more than 20%. The opinions are varied as to the risk factors affecting the development of schizophrenia. Knowing these factors may greatly contribute to prevention of the condition.
    MeSH term(s) Environment ; Female ; Genetic Predisposition to Disease ; Humans ; Infant, Newborn ; Parturition/physiology ; Pregnancy ; Prevalence ; Risk Factors ; Schizophrenia/epidemiology ; Schizophrenia/etiology ; Substance-Related Disorders/complications ; Substance-Related Disorders/epidemiology
    Language English
    Publishing date 2016
    Publishing country Sweden
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 135951-4
    ISSN 0172-780X
    ISSN 0172-780X
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Arachidonate 5-lipoxygenase (ALOX5) gene polymorphism is associated with Alzheimer's disease and body mass index.

    Šerý, Omar / Hlinecká, Lýdia / Povová, Jana / Bonczek, Ondřej / Zeman, Tomáš / Janout, Vladimír / Ambroz, Petr / Khan, Naim A / Balcar, Vladimir J

    Journal of the neurological sciences

    2016  Volume 362, Page(s) 27–32

    Abstract: Dementias of old age, in particular Alzheimer's disease (AD), pose a growing threat to the longevity and quality of life of individuals as well as whole societies world-wide. The risk factors are both genetic and environmental (life-style) and there is ... ...

    Abstract Dementias of old age, in particular Alzheimer's disease (AD), pose a growing threat to the longevity and quality of life of individuals as well as whole societies world-wide. The risk factors are both genetic and environmental (life-style) and there is an overlap with similar factors predisposing to cardiovascular diseases (CVD). Using a case-control genetic approach, we have identified a SNP (rs10507391) in ALOX5 gene, previously associated with an increased risk of stroke, as a novel genetic risk factor for AD. ALOX5 gene encodes a 5'-lipoxygenase (5'-LO) activating protein (FLAP), a crucial component of the arachidonic acid/leukotriene inflammatory cascade. A-allele of rs4769874 polymorphism increases the risk of AD 1.41-fold (p<0.0001), while AA genotype does so 1.79-fold (p<0.0001). In addition, GG genotype of rs4769874 polymorphism is associated with a modest increase in body mass index (BMI). We discuss potential biochemical mechanisms linking the SNP to AD and suggest possible preventive pharmacotherapies some of which are based on commonly available natural products. Finally, we set the newly identified AD risk factors into a broader context of similar CVD risk factors to generate a more comprehensive picture of interacting genetics and life-style habits potentially leading to the deteriorating mental health in the old age.
    MeSH term(s) Aged ; Aged, 80 and over ; Alzheimer Disease/genetics ; Alzheimer Disease/physiopathology ; Alzheimer Disease/psychology ; Arachidonate 5-Lipoxygenase/genetics ; Body Mass Index ; Body Weight/genetics ; Czech Republic ; Female ; Genetic Association Studies ; Genotype ; Humans ; Life Style ; Male ; Polymorphism, Single Nucleotide/genetics ; Surveys and Questionnaires
    Chemical Substances Arachidonate 5-Lipoxygenase (EC 1.13.11.34) ; ALOX5 protein, human (EC 1.3.11.34)
    Language English
    Publishing date 2016-03-15
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80160-4
    ISSN 1878-5883 ; 0022-510X ; 0374-8642
    ISSN (online) 1878-5883
    ISSN 0022-510X ; 0374-8642
    DOI 10.1016/j.jns.2016.01.022
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Corrigendum to 'Arachidonate 5-Lipoxygenase (ALOX5) gene polymorphism is associated with Alzheimer's disease and body mass index [Šerý et al., J. Neurol. Sci. 362 (2016) 27-32].

    Šerý, Omar / Hlinecká, Lydia / Povová, Jana / Bonczek, Ondřej / Zeman, Tomáš / Janout, Vladimír / Ambroz, Petr / Khan, Naim A / Balcar, Vladimir J

    Journal of the neurological sciences

    2016  Volume 366, Page(s) 135

    Language English
    Publishing date 2016--15
    Publishing country Netherlands
    Document type Journal Article ; Published Erratum
    ZDB-ID 80160-4
    ISSN 1878-5883 ; 0022-510X ; 0374-8642
    ISSN (online) 1878-5883
    ISSN 0022-510X ; 0374-8642
    DOI 10.1016/j.jns.2016.05.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Book ; Online: Proceedings 8th International Conference Words 2011

    Ambrož, Petr / Holub, Štěpán / Masáková, Zuzana

    2011  

    Abstract: WORDS is the main international event in Combinatorics on Words. It is a biannual conference devoted to research of words (i.e., finite or infinite sequences of symbols over a finite alphabet) from combinatorial, algebraic and algorithmic points of view. ...

    Abstract WORDS is the main international event in Combinatorics on Words. It is a biannual conference devoted to research of words (i.e., finite or infinite sequences of symbols over a finite alphabet) from combinatorial, algebraic and algorithmic points of view. The emphasis of the conference is on mathematical theory of words but the conference is also open to applications, mainly in computer science, biology, linguistics and physics, gaining from the fact that words arise as a natural object in many areas. The eighth edition of the conference was organized in Prague from 12th to 16th September 2011 as a joint undertaking of the Czech Technical University and the Charles University. This volume consists of contributed papers accepted for presentation at the conference and summaries of invited lectures.

    Comment: EPTCS 63, 2011
    Keywords Computer Science - Formal Languages and Automata Theory
    Publishing date 2011-08-17
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  9. Article: Epidemiological of and risk factors for Alzheimer's disease: a review.

    Povova, Jana / Ambroz, Petr / Bar, Michal / Pavukova, Veronika / Sery, Omar / Tomaskova, Hana / Janout, Vladimir

    Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia

    2012  Volume 156, Issue 2, Page(s) 108–114

    Abstract: Background: Alzheimer's disease (AD) is the most common form of dementia. It is a degenerative, incurable and terminal disease. The increasing prevalence of AD is, among other reasons, due to population aging, which is, to a certain extent, seen ... ...

    Abstract Background: Alzheimer's disease (AD) is the most common form of dementia. It is a degenerative, incurable and terminal disease. The increasing prevalence of AD is, among other reasons, due to population aging, which is, to a certain extent, seen worldwide. Continuous advances in health care keep increasing life expectancy. Official statistics are likely to significantly underestimate the actual prevalence of AD. Alzheimer's disease represents an important public health problem. Its aetiology is still unknown and for this reason, it is necessary to study all potential risk factors which may contribute to the development of this disease.
    Methods: We searched original and review articles addressing Alzheimer's disease using key words Alzheimer's disease, epidemiology, risk factors and prevention. We found and used one hundred and four references.
    Conclusions: Based on epidemiological studies, genetic studies, neuroimaging methods and neuropathology research, three basic etiological hypotheses of the development of AD have been formulated: genetic, vascular and psychosocial. At present, the level of evidence is insufficient for the etiological role of other factors, such as nutrition, occupational exposure to various substances and inflammation. From the point of view of early diagnosis and application of primary or secondary prevention principles, genetic factors are the most important.
    MeSH term(s) Alzheimer Disease/epidemiology ; Alzheimer Disease/etiology ; Alzheimer Disease/prevention & control ; Humans ; Incidence ; Prevalence ; Risk Factors
    Language English
    Publishing date 2012-06
    Publishing country Czech Republic
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 17196-7
    ISSN 1804-7521 ; 1213-8118 ; 0231-5599 ; 0862-481X
    ISSN (online) 1804-7521
    ISSN 1213-8118 ; 0231-5599 ; 0862-481X
    DOI 10.5507/bp.2012.055
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article: Combined exposure of carps (Cyprinus carpio L.) to cyanobacterial biomass and white spot disease.

    Palikova, Miroslava / Navratil, Stanislav / Papezikova, Ivana / Ambroz, Petr / Vesely, Tomas / Pokorova, Dagmar / Mares, Jan / Adamovsky, Ondrej / Navratil, Lukas / Kopp, Radovan

    Neuro endocrinology letters

    2012  Volume 33 Suppl 3, Page(s) 77–83

    Abstract: Objectives: Under environmental conditions, fish can be exposed to multiple stressors including natural toxins and infectious agents at the same time. This study brings new knowledge on the effects of controlled exposure to multiple stressors in fish. ... ...

    Abstract Objectives: Under environmental conditions, fish can be exposed to multiple stressors including natural toxins and infectious agents at the same time. This study brings new knowledge on the effects of controlled exposure to multiple stressors in fish. The aim of this study was to test the hypothesis that influence of cyanobacterial biomass and an infection agent represented by the white spot disease can combine to enhance the effects on fish.
    Methods: Common carps were divided into four groups, each with 40 specimens for 20 days: control group, cyanobacterial biomass exposed group, Ichthyophthirius multifiliis-infected fish (Ich) and cyanobacterial biomass-exposed fish + Ichthyophthirius multifiliis-infected fish. During the experiment we evaluated the clinical signs, mortality, selected haematological parameters, immune parameters and toxin accumulation.
    Results: There was no mortality in control fish and cyanobacterial biomass-exposed fish. One specimen died in Ichthyophthirius multifiliis-infected fish and the combined exposure resulted in the death of 13 specimens. The whole leukocyte counts (WBC) of the control group did not show any significant differences. Cyanobacteria alone caused a significant increase of the WBC on day 13 (p≤0.05) and on day 20 (p≤0.01). Also, I. multifiliis caused a significant elevation of WBC (p≤0.01) on day 20. Co-exposition resulted in WBC increased on day 13 and decrease on day 20, but the changes were not significant. It is evident from the differential leukocyte counts that while the increase of WBC in the group exposed to cyanobacteria was caused by elevation of lymphocytes, the increase in the group infected by I. multifiliis was due to the increase of myeloid cells. It well corresponds with the integral of chemiluminescence in the group infected by I. multifiliis, which is significantly elevated on day 20 in comparison with all other groups.
    Conclusions: We can confirm additive action of different agents on the immune system of fish. While single agents seemed to stimulate the immune response, the combination of both caused immunosuppression.
    MeSH term(s) Animals ; Bacterial Toxins/toxicity ; Biomass ; Carcinogens/toxicity ; Carps/immunology ; Ciliophora ; Cyanobacteria/growth & development ; Cyanobacteria/pathogenicity ; Fish Diseases/immunology ; Fish Diseases/microbiology ; Fish Diseases/parasitology ; Immune System/immunology ; Leukocyte Count ; Marine Toxins/toxicity ; Microcystins/toxicity ; Protozoan Infections/immunology ; Stress, Physiological/immunology
    Chemical Substances Bacterial Toxins ; Carcinogens ; Marine Toxins ; Microcystins ; cyanobacterial toxin
    Language English
    Publishing date 2012
    Publishing country Sweden
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 135951-4
    ISSN 0172-780X
    ISSN 0172-780X
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top