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Article: Effects of citalopram on blood pressure control in depressive patients with hypertension: A randomized clinical trial.

Namdar, Hossein / Khani, Elnaz / Khiali, Sajad / Safaie, Naser / Ameli, Hedieh / Rahbari Banaeian, Gholamreza / Entezari-Maleki, Taher

Journal of cardiovascular and thoracic research

2024  Volume 16, Issue 1, Page(s) 49–54

Abstract: Introduction: Since there is a bi-directional interaction between hypertension and depression, we aimed to evaluate the effects of citalopram administration in the management of hypertension.: Methods: A randomized clinical trial was conducted on 72 ... ...

Abstract Introduction: Since there is a bi-directional interaction between hypertension and depression, we aimed to evaluate the effects of citalopram administration in the management of hypertension.
Methods: A randomized clinical trial was conducted on 72 patients with concomitant depression and hypertension. The intervention group (n=41) received citalopram 20 mg daily plus anti-hypertensive standard treatment, while the control group (n=31) received only the standard treatment. The study's primary endpoint was in-office blood pressure (BP) measurement at baseline and home BP monitoring in the first and second months after entering the study.
Results: There were no significant differences in baseline systolic BP (163.3±19.6 vs.164.2±20.3 mm Hg;
Conclusion: This study supported the beneficial effects of citalopram in lowering BP in patients with concomitant depression and hypertension.
Language English
Publishing date 2024-03-13
Publishing country Iran
Document type Journal Article
ZDB-ID 2654729-6
ISSN 2008-6830 ; 2008-5117
ISSN (online) 2008-6830
ISSN 2008-5117
DOI 10.34172/jcvtr.31849
Database MEDical Literature Analysis and Retrieval System OnLINE

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