LIVIVO - Search results -

Search results

Result 1 - 10 of total 71

Search options

Article ; Online: Special Issue-"Natural Products That Might Change Society".

Amen, Yhiya / Shimizu, Kuniyoshi

2024 Volume 29, Issue 5

Abstract: This Special Issue ... ...

Abstract	This Special Issue of
MeSH term(s)	Humans ; Biological Products
Chemical Substances	Biological Products
Language	English
Publishing date	2024-02-26
Publishing country	Switzerland
Document type	Editorial
ZDB-ID	1413402-0
ISSN	1420-3049 ; 1431-5165 ; 1420-3049
ISSN (online)	1420-3049
ISSN	1431-5165 ; 1420-3049
DOI	10.3390/molecules29051008
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.MO 81: Show issues

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Phytochemical, ethnomedicinal uses and pharmacological profile of

Ullah, Sana / Amen, Yhiya / Shimizu, Kuniyoshi

Natural product research

2023 , Page(s) 1–11

Abstract: ... Juncus ... ...

Abstract	Juncus decipiens
Language	English
Publishing date	2023-06-13
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2185747-7
ISSN	1478-6427 ; 1478-6419
ISSN (online)	1478-6427
ISSN	1478-6419
DOI	10.1080/14786419.2023.2223749
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Bioactivity of Eriocephalus africanus essential oil against concanavalin A-induced hepatitis via suppressing immune cell infiltration, inhibiting TNF-α/NF-κB and IFN-γ/STAT1 signaling pathways

Haikal, Abdullah / Galala, Amal A. / Elshal, Mahmoud / Amen, Yhiya / Gohar, Ahmed A.

Journal of Ethnopharmacology. 2024 Jan., v. 318 p.117000-

2024

Abstract: Eriocephalus africanus infusion is used as a diuretic and a diaphoretic and is also used in the treatment of gastrointestinal disorders and gynaecological conditions, inflammation and dermal disorders, asthma, coughs, fevers, and painful ailments. The ... ...

Abstract	Eriocephalus africanus infusion is used as a diuretic and a diaphoretic and is also used in the treatment of gastrointestinal disorders and gynaecological conditions, inflammation and dermal disorders, asthma, coughs, fevers, and painful ailments. The plant has been used traditionally as a medication to cure inflammation and skin problems. Studying E. africanus essential oil (EAEO) as a potential hepatoprotective measure against concanavalin (Con) A-induced hepatitis in mice and investigating its underlying mechanism. Hydro-distilled oil of the fresh plant aerial shoots is subjected to GC/MS analysis. Autoimmune hepatitis (AIH) was induced in mice by intravenous injection of Con A (15 mg/kg). EAEO was administered orally before Con A injection to test its hepatoprotective activity. GC/MS analysis revealed the presence of 22 compounds representing 99.43% of the oil components. The monoterpene artemisia ketone (41.02%) and the sesquiterpene juniper camphor (14.17%) are the major components. The in vivo study showed that the oil suppressed Con A-induced neutrophil and CD4+T cell infiltration into the liver, restored hepatic redox balance, inhibited Con A-induced elevation of tumor necrosis factor-alpha (TNF-α), interleukin (IL-6), and interferon-gamma (IFN-γ) hepatic levels which were correlated with its ability to suppress nuclear factor kappa B (NF-κB) and Signal Transducer and Activator of Transcription (STAT1) activation in the liver. EAEO showed hepatoprotective potential against Con A-induced hepatitis in mice collectively through selective anti-oxidant, anti-inflammatory, and anti-necrotic effects.
Keywords	Eriocephalus ; antioxidants ; asthma ; autoimmune hepatitis ; camphor ; essential oils ; gastrointestinal system ; hepatoprotective effect ; inflammation ; interferon-gamma ; interleukin-6 ; intravenous injection ; ketones ; liver ; neutrophils ; oils ; sesquiterpenoids ; signal transduction ; traditional medicine ; transactivators ; transcription factor NF-kappa B ; tumor necrosis factor-alpha ; Eriocephalus africanus var. africanus ; Essential oil ; Concanavalin A ; Artemisia ketone
Language	English
Dates of publication	2024-01
Publishing place	Elsevier B.V.
Document type	Article ; Online
ZDB-ID	134511-4
ISSN	1872-7573 ; 0378-8741
ISSN (online)	1872-7573
ISSN	0378-8741
DOI	10.1016/j.jep.2023.117000
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Bonn / Germany

Z 90/710: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Unveiling the Antiviral Efficacy of Forskolin: A Multifaceted In Vitro and In Silico Approach.

Amen, Yhiya / Selim, Mohamed A / Suef, Reda A / Sayed, Ahmed M / Othman, Ahmed

Molecules (Basel, Switzerland)

2024 Volume 29, Issue 3

Abstract: ... Coleus ... ...

Abstract	Coleus forskohlii
MeSH term(s)	Colforsin/pharmacology ; Colforsin/chemistry ; Cathepsin L ; Molecular Docking Simulation ; Herpesvirus 1, Human/metabolism ; Antiviral Agents/pharmacology ; Antiviral Agents/chemistry
Chemical Substances	Colforsin (1F7A44V6OU) ; Cathepsin L (EC 3.4.22.15) ; Antiviral Agents
Language	English
Publishing date	2024-02-03
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	1413402-0
ISSN	1420-3049 ; 1431-5165 ; 1420-3049
ISSN (online)	1420-3049
ISSN	1431-5165 ; 1420-3049
DOI	10.3390/molecules29030704
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.MO 81: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Anti-phototoxicity and anti-melanogenesis activities of eelgrass Zostera marina and its phenolic constituents.

Elkattan, Amira / Amen, Yhiya / Matsumoto, Masako / Nagata, Maki / Mittraphab, Yanisa / Shimizu, Kuniyoshi

Fitoterapia

2024 Volume 173, Page(s) 105817

Abstract: The eelgrass Zostera marina L. has several economic roles, from its earlier usage in the insulation industry to protecting the earth from global warming. In this study, we aimed to discover the cosmetic potential of Z. marina. A methanolic extract of Z. ... ...

Abstract	The eelgrass Zostera marina L. has several economic roles, from its earlier usage in the insulation industry to protecting the earth from global warming. In this study, we aimed to discover the cosmetic potential of Z. marina. A methanolic extract of Z. marina showed anti-phototoxicity and anti-melanogenesis activity with an IC
MeSH term(s)	Zosteraceae/chemistry ; Luteolin ; Molecular Structure ; Rosmarinic Acid ; Lactates
Chemical Substances	3-phenyllactic acid (156-05-8) ; Luteolin (KUX1ZNC9J2) ; Rosmarinic Acid (MQE6XG29YI) ; Lactates
Language	English
Publishing date	2024-01-02
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	412385-2
ISSN	1873-6971 ; 0367-326X
ISSN (online)	1873-6971
ISSN	0367-326X
DOI	10.1016/j.fitote.2023.105817
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 1873: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Undescribed glucosylceramide, flavonol triglycoside, and oleanane saponin from the halophyte Agathophora alopecuroides: Promising candidates for stimulating ceramide synthesis.

Othman, Ahmed / Amen, Yhiya / Nagata, Maki / Shimizu, Kuniyoshi

Phytochemistry

2022 Volume 202, Page(s) 113320

Abstract: The phytochemical study of Agathophora alopecuroides (Chenopodiaceae) led to the isolation of previously undescribed glucosylceramide, flavonol triglycoside, and triterpene oleanane saponin, together with eight known compounds. Their structures were ... ...

Abstract	The phytochemical study of Agathophora alopecuroides (Chenopodiaceae) led to the isolation of previously undescribed glucosylceramide, flavonol triglycoside, and triterpene oleanane saponin, together with eight known compounds. Their structures were elucidated using NMR analysis and HR-MS as (2'R, 12E) N-[(2S, 3S, 4R)-1-(β-D-glucopyranosyloxy)-3,4-dihydroxy-octadec-2-yl]-2-hydroxytetracos-12-enamide, namely Agathophamide A; isorhamnetin-3-O-[β-D-xylopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→6)]-β-D-galactopyranoside, namely Agathophoroside A; and 3-O-[4'-(β-D-xylopyranosyl)-β-D-glucuronopyranosyl]-28-O-β-D-glucopyranosyl-olean-12-en-3β-ol-28-oic acid, namely Solysaponin A. We evaluated the effect of extract and isolates on ceramide levels via the up-regulated expression of the enzyme for ceramide synthesis in HaCaT keratinocytes. Interestingly, the study results revealed that the methanol extract of A. alopecuroides, together with some isolated compounds significantly up-regulated the mRNA expression of ceramide synthase-3 by 1.2- to 4.3-fold compared with the control in HaCaT cells. These findings indicate that the halophyte A. alopecuroides is a promising source of candidate compounds that can contribute to ceramide synthesis via the up-regulated expression levels of ceramide synthase-3 in the ceramide synthesis pathway.
MeSH term(s)	Chenopodiaceae ; Flavonols/pharmacology ; Glucosylceramides ; Oleanolic Acid/analogs & derivatives ; Plant Extracts/chemistry ; Salt-Tolerant Plants ; Saponins/chemistry ; Saponins/pharmacology ; Triterpenes/chemistry
Chemical Substances	Flavonols ; Glucosylceramides ; Plant Extracts ; Saponins ; Triterpenes ; oleanane ; Oleanolic Acid (6SMK8R7TGJ)
Language	English
Publishing date	2022-07-14
Publishing country	England
Document type	Journal Article
ZDB-ID	208884-8
ISSN	1873-3700 ; 0031-9422
ISSN (online)	1873-3700
ISSN	0031-9422
DOI	10.1016/j.phytochem.2022.113320
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Bonn / Germany

Z 1586: Show issues
Z 8.5: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article: Undescribed glucosylceramide, flavonol triglycoside, and oleanane saponin from the halophyte Agathophora alopecuroides: Promising candidates for stimulating ceramide synthesis

Othman, Ahmed / Amen, Yhiya / Nagata, Maki / Shimizu, Kuniyoshi

Phytochemistry. 2022 Oct., v. 202

2022

Abstract	The phytochemical study of Agathophora alopecuroides (Chenopodiaceae) led to the isolation of previously undescribed glucosylceramide, flavonol triglycoside, and triterpene oleanane saponin, together with eight known compounds. Their structures were elucidated using NMR analysis and HR-MS as (2′R, 12E) N-[(2S, 3S, 4R)-1-(β-D-glucopyranosyloxy)-3,4-dihydroxy-octadec-2-yl]-2-hydroxytetracos-12-enamide, namely Agathophamide A; isorhamnetin-3-O-[β-D-xylopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→6)]-β-D-galactopyranoside, namely Agathophoroside A; and 3-O-[4'-(β-D-xylopyranosyl)-β-D-glucuronopyranosyl]-28-O-β-D-glucopyranosyl-olean-12-en-3β-ol-28-oic acid, namely Solysaponin A. We evaluated the effect of extract and isolates on ceramide levels via the up-regulated expression of the enzyme for ceramide synthesis in HaCaT keratinocytes. Interestingly, the study results revealed that the methanol extract of A. alopecuroides, together with some isolated compounds significantly up-regulated the mRNA expression of ceramide synthase-3 by 1.2- to 4.3-fold compared with the control in HaCaT cells. These findings indicate that the halophyte A. alopecuroides is a promising source of candidate compounds that can contribute to ceramide synthesis via the up-regulated expression levels of ceramide synthase-3 in the ceramide synthesis pathway.
Keywords	Amaranthaceae ; ceramides ; enzymes ; flavonols ; gene expression ; glucosylceramides ; halophytes ; keratinocytes ; methanol ; saponins ; triterpenoids
Language	English
Dates of publication	2022-10
Publishing place	Elsevier Ltd
Document type	Article
ZDB-ID	208884-8
ISSN	1873-3700 ; 0031-9422
ISSN (online)	1873-3700
ISSN	0031-9422
DOI	10.1016/j.phytochem.2022.113320
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Bonn / Germany

Z 1586: Show issues
Z 8.5: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article: Validation of the potential anti-inflammatory activity of Plumbago auriculata Lam

Sherif, Asmaa E. / Amen, Yhiya / Shimizu, Kuniyoshi

SAAB South African journal of botany. 2022 July, v. 147

2022

Abstract: This study targets scientific validation of the claimed anti-inflammatory activity of Plumbago auriculata Lam. The total methanolic extract of the aerial parts of P. auriculata Lam. and its different fractions were evaluated for their anti-inflammatory ... ...

Abstract	This study targets scientific validation of the claimed anti-inflammatory activity of Plumbago auriculata Lam. The total methanolic extract of the aerial parts of P. auriculata Lam. and its different fractions were evaluated for their anti-inflammatory activity using carrageenan-induced paw edema model in rats followed by bio-guided isolation of the anti-inflammatory principles from the active fractions. As a result, sixteen compounds were isolated and identified based on different spectroscopic techniques. Two of them exhibited significant anti-inflammatory activities proved through inhibition of the paw swelling by 81.4 ± 0.2 and 85.2 ± 3.6% at a dose of 10 mg/kg, while the others exhibited varying activities. Throughout the study, some compounds are reported for the first time, of them, a unique polyoxygenated chromone-C-glucoside; biflorin together with a well-known coumarin; umbelliferone, are of a great importance for their chemotaxonomic significance of the studied species.
Keywords	Plumbago auriculata ; anti-inflammatory activity ; chemotaxonomy ; coumarin ; edema ; models ; spectroscopy ; umbelliferones
Language	English
Dates of publication	2022-07
Size	p. 467-471.
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	2126918-X
ISSN	0254-6299
ISSN	0254-6299
DOI	10.1016/j.sajb.2022.01.028
Database	NAL-Catalogue (AGRICOLA)

Order via subito

Article ; Online: Acetylcholinesterase inhibitors from Conocarpus lancifolius Engl. (Combretaceae)

Abdel Bar, Fatma M. / Salkini, Ayman A. / Amen, Yhiya / Sherif, Asmaa E.

Natural Product Research. 2023 May 19, v. 37, no. 10 p.1668-1673

2023

Abstract: Conocarpus lancifolius Engl. (Combretaceae) has several potential health-promoting effects, such as antidiabetic, antimicrobial, antioxidant, and cytotoxic effects. Phytochemical study of the ethyl acetate fraction of the leaf extract of this plant led ... ...

Abstract	Conocarpus lancifolius Engl. (Combretaceae) has several potential health-promoting effects, such as antidiabetic, antimicrobial, antioxidant, and cytotoxic effects. Phytochemical study of the ethyl acetate fraction of the leaf extract of this plant led to the isolation and identification of eight compounds viz., gallic acid (1), dihydromyricetin (2), myricetin (3), daucosterol (4), syringetin 3-O-β-D-glucopyranoside (5), quercetin 3-O-β-D-glucoside (6), gallocatechin (7), and (-)-epigallocatechin-3-O-gallate (8). Their acetylcholinesterase (AChE) in vitro and in silico inhibitory activities were evaluated. Daucosterol (4) showed the highest activity (IC₅₀ 0.316 μM) which was further validated by the superimposed docking orientation with the co-crystallized inhibitor, donepezil.
Keywords	Conocarpus ; acetylcholinesterase ; antioxidants ; computer simulation ; cytotoxicity ; epigallocatechin ; ethyl acetate ; gallic acid ; health promotion ; leaf extracts ; myricetin ; quercetin ; research ; Conocarpus lancifolius ; acetylcholinesterase inhibitor ; syringetin 3-O-glucoside ; dihydromyricetin
Language	English
Dates of publication	2023-0519
Size	p. 1668-1673.
Publishing place	Taylor & Francis
Document type	Article ; Online
ZDB-ID	2185747-7
ISSN	1478-6427 ; 1478-6419
ISSN (online)	1478-6427
ISSN	1478-6419
DOI	10.1080/14786419.2022.2103124
Database	NAL-Catalogue (AGRICOLA)

Order via subito

Article ; Online: A novel acylated flavonol tetraglycoside and rare oleanane saponins with a unique acetal-linked dicarboxylic acid substituent from the xero-halophyte Bassia indica.

Othman, Ahmed / Amen, Yhiya / Shimizu, Kuniyoshi

Fitoterapia

2021 Volume 152, Page(s) 104907

Abstract: In recent years, the scientific interest and particularly the economic significance of halophytic plants has been highly demanding due to the medicinal and nutraceutical potential of its bioactive compounds. A xero-halophyte Bassia indica is deemed to be ...

Abstract	In recent years, the scientific interest and particularly the economic significance of halophytic plants has been highly demanding due to the medicinal and nutraceutical potential of its bioactive compounds. A xero-halophyte Bassia indica is deemed to be a very cheap source of natural entities without chemical or biological investigation. In this context, a new acylated flavonol tetraglycoside, kaempferol-3-O-β-d-glucopyranosyl-(1→6)-O-[β-D-galactopyranosyl-(1→3)-2-O-trans-feruloyl-α-L-rhamnopyranosyl-(1→2)]-β-D-glucopyranoside (14), together with rare occurring flavonol triglycoside, isorhamnetin-3-O-β-d-glucopyranosyl-(1→6)-O-[α-L-rhamnopyranosyl-(1→2)]-β-D-glucopyranoside (15), were isolated from the aqueous methanol extract of the aerial parts of B. indica. The study also reported an optimal separation and characterization of a new seco-glycosidic oleanane saponin with 2'R,3'S stereocenters, identified as (2'R,3'S)-3-O-[2'-hydroxy-3'-(2"-O-glycolyl)-oxo-propionic acid-β-D-glucuronopyranosyl]-28-O-β-D-glucopyranosyl-olean-12-en-3β-ol-28-oic acid (17), in addition to its derivative, 3-O-[2'-(2"-O-glycolyl)-glyoxylyl-β-D-glucuronopyranosyl]-28-O-β-d-glucopyranosyl-olean-12-en-3β-ol-28-oic acid (16). The structures of all isolated compounds were elucidated based on 1D, 2D NMR, and HR-MS analysis, as well as comparing with similar derivatives published in the literature. Furthermore, thirteen known compounds were isolated and identified as β-sitosterol (1), vanillic acid (2), o-hydroxybenzoic acid (3), р-hydroxybenzoic acid (4), 6,7-dihydroxycoumarin (5), methyl caffeate (6), caffeic acid (7), quercetin (8), uracil (9), thymidine (10), tachioside (11), isorhamnetin-3-O-β-D-glucopyranoside (12), kaempferol-3-O-rutinoside (13). The anticholinesterase activity of all isolated compounds was evaluated.
MeSH term(s)	Acetals ; Chenopodiaceae/chemistry ; Cholinesterase Inhibitors/isolation & purification ; Cholinesterase Inhibitors/pharmacology ; Dicarboxylic Acids ; Egypt ; Flavonols/isolation & purification ; Flavonols/pharmacology ; Glycosides/isolation & purification ; Glycosides/pharmacology ; Molecular Structure ; Oleanolic Acid/analogs & derivatives ; Oleanolic Acid/isolation & purification ; Oleanolic Acid/pharmacology ; Phytochemicals/isolation & purification ; Phytochemicals/pharmacology ; Plant Components, Aerial/chemistry ; Salt-Tolerant Plants/chemistry ; Saponins/isolation & purification ; Saponins/pharmacology
Chemical Substances	Acetals ; Cholinesterase Inhibitors ; Dicarboxylic Acids ; Flavonols ; Glycosides ; Phytochemicals ; Saponins ; oleanane ; Oleanolic Acid (6SMK8R7TGJ)
Language	English
Publishing date	2021-04-20
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	412385-2
ISSN	1873-6971 ; 0367-326X
ISSN (online)	1873-6971
ISSN	0367-326X
DOI	10.1016/j.fitote.2021.104907
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 1873: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito