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  1. Article ; Online: What Can the Developing World (and Others) Learn From the Indian Experience in Crossing the ABO Blood Group Barrier in Kidney Transplantation.

    Amer, Hatem

    Transplantation

    2023  Volume 108, Issue 2, Page(s) 329–330

    MeSH term(s) Kidney Transplantation ; ABO Blood-Group System ; Graft Rejection ; Immunosuppressive Agents ; Blood Group Incompatibility
    Chemical Substances ABO Blood-Group System ; Immunosuppressive Agents
    Language English
    Publishing date 2023-08-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208424-7
    ISSN 1534-6080 ; 0041-1337
    ISSN (online) 1534-6080
    ISSN 0041-1337
    DOI 10.1097/TP.0000000000004790
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 488: Show issues Location:
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    Zs.MO 509: Show issues

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  2. Article ; Online: Best Practice for Induction of Immunosuppression in Patients Treated With Daratumumab Is to Be Determined.

    Amer, Hatem / Leung, Nelson

    American journal of kidney diseases : the official journal of the National Kidney Foundation

    2023  Volume 83, Issue 1, Page(s) 116

    MeSH term(s) Humans ; Antibodies, Monoclonal/therapeutic use ; Multiple Myeloma/therapy ; Immunosuppression Therapy ; Patients ; Antineoplastic Combined Chemotherapy Protocols
    Chemical Substances daratumumab (4Z63YK6E0E) ; Antibodies, Monoclonal
    Language English
    Publishing date 2023-08-29
    Publishing country United States
    Document type Letter
    ZDB-ID 604539-x
    ISSN 1523-6838 ; 0272-6386
    ISSN (online) 1523-6838
    ISSN 0272-6386
    DOI 10.1053/j.ajkd.2023.05.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1669: Show issues Location:
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    Zs.MO 468: Show issues

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  3. Article ; Online: Expression of Aberrant MicroRNAs and p16INK4a Associated with HPV (6, 11, 16, 18, 31, 33, 35, 42, 43, 44, 45, 52, 53, and 56) in Oral Dysplasia and Squamous Cell Carcinoma: A Retrospective Study.

    Hafed, Layla / Shaker, Olfat / Ayeldeen, Ghada / Amer, Hatem / Al-Qadhi, Gamilah

    Turk patoloji dergisi

    2024  

    Abstract: Objective: A few studies indicate that human papillomavirus (HPV) induces aberrant expression of microRNAs (miRNAs) and correlate this with p16INK4a in oral dysplasia (OD) and oral squamous cell carcinoma (OSCC). Therefore, this study aimed to evaluate ... ...

    Title translation Expression of Aberrant MicroRNAs and p16INK4a Associated with HPV (6, 11, 16, 18, 31, 33, 35, 42, 43, 44, 45, 52, 53, and 56) in Oral Dysplasia and Squamous Cell Carcinoma: A Retrospective Study.
    Abstract Objective: A few studies indicate that human papillomavirus (HPV) induces aberrant expression of microRNAs (miRNAs) and correlate this with p16INK4a in oral dysplasia (OD) and oral squamous cell carcinoma (OSCC). Therefore, this study aimed to evaluate the expression of miRNA-21, miRNA-22, and miRNA-224 by q-PCR and the p16 INK4a by immunohistochemical (IHC) as markers for HPV-positive OSCC and OD in comparison to controls as miRNA expression can be altered by the HPV oncogenes and hence can be used as a biomarker for HPV positive cases.
    Material and methods: Fifty-two specimens were collected from archived paraffin blocks for patients aged between 19 and 88 (31 males and 21 females) from various oral sites. They were examined by IHC using p16 INK4a, by RT-PCR for the detection of HPV (6, 11, 16, 18, 31, 33, 35, 42, 43, 44, 45, 52, 53, 56), and by q-PCR for the expression of miRNA-21, miRNA-22, and miRNA-224 in positive specimens.
    Results: Out of the 15 OD, three were positive by both techniques. Meanwhile, 17 out of all OSCC specimens showed intense nuclear and cytoplasmic staining by p16 INK4a, and only 16 were also positive by RT-PCR. However, all control specimens were negative. MiRNA-21, miRNA-22, and miRNA-224 were overexpressed in 3 specimens of OD and 16 of OSCC.
    Conclusion: MiRNA-21, miRNA-22, and miRNA-224, besides p16 INK4a, could be used as indicators for HPV-associated OD and OSCC as their expression is attributed to the HPV oncoprotein. Further studies using follow-up data should be done to correlate it with miRNA overexpression.
    Language English
    Publishing date 2024-03-26
    Publishing country Turkey
    Document type Journal Article
    ZDB-ID 2515899-5
    ISSN 1309-5730 ; 1309-5730
    ISSN (online) 1309-5730
    ISSN 1309-5730
    DOI 10.5146/tjpath.2024.12909
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  4. Article ; Online: Ameloblastic fibro-dentinoma: a rare mixed odontogenic tumor case report with review of literature.

    Darwish, Nihal Mohamed Ahmed / Amer, Hatem Wael Abdel-Fattah / Mahrous, Nesma Nabil Mohamed

    Journal of the Egyptian National Cancer Institute

    2023  Volume 35, Issue 1, Page(s) 34

    Abstract: Background: Ameloblastic fibro-dentinoma is considered a rare, benign, mixed odontogenic tumor that occurs mainly in the posterior mandible in the 1st-2nd decade of life. Although the clinical behavior of Ameloblastic fibro-dentinoma is similar to that ... ...

    Abstract Background: Ameloblastic fibro-dentinoma is considered a rare, benign, mixed odontogenic tumor that occurs mainly in the posterior mandible in the 1st-2nd decade of life. Although the clinical behavior of Ameloblastic fibro-dentinoma is similar to that of ameloblastic fibroma, there is a debate about whether Ameloblastic fibro-dentinoma is a developing hamartomatous odontoma or a separate neoplastic odontogenic tumor like ameloblastic fibroma. However, it is important to understand the histopathogenesis of this rare tumor.
    Case presentation: A case report presenting an 11-year-old male child with a swelling in the posterior mandible. Radiographic examination revealed a multilocular lesion with mixed radiodensity related to the impacted lower left second premolar tooth. Incisional biopsy was done, and microscopic examination revealed cords and nests of odontogenic follicles lined by ameloblast-like cells and central stellate reticulum-like cells in the primitive ecto-mesenchymal stroma with areas of dentinoid material and osteodentin. The diagnosis was ameloblastic fibro-dentinoma. Surgical excision of the lesion was done, and the patient was followed up for 1 year without evidence of recurrence.
    Conclusion: Reporting such a rare entity clarifies the debate about its nature and the importance of early diagnosis of lesions that are associated with unerupted teeth showing how it is effective in early management and prognosis.
    MeSH term(s) Male ; Child ; Humans ; Mandibular Neoplasms/diagnostic imaging ; Mandibular Neoplasms/surgery ; Ameloblasts/pathology ; Odontogenic Tumors/diagnostic imaging ; Odontogenic Tumors/surgery ; Odontoma/diagnostic imaging ; Odontoma/surgery ; Fibroma
    Language English
    Publishing date 2023-10-30
    Publishing country England
    Document type Review ; Case Reports ; Journal Article
    ZDB-ID 1176790-x
    ISSN 2589-0409 ; 1110-0362
    ISSN (online) 2589-0409
    ISSN 1110-0362
    DOI 10.1186/s43046-023-00193-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3918: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Mandibular small cell osteosarcoma: a case report and review of literature.

    Amer, Hatem Wael / Algadi, Hana'a Hezam / Hamza, Shyma'a Ahmed

    Journal of the Egyptian National Cancer Institute

    2023  Volume 35, Issue 1, Page(s) 30

    Abstract: Background: Small cell osteosarcoma is an extremely rare histopathological variant of conventional osteosarcoma. Due to nonspecific symptoms, most osteosarcomas of the jaws are misdiagnosed as periapical abscesses and mistreated by teeth extraction and ... ...

    Abstract Background: Small cell osteosarcoma is an extremely rare histopathological variant of conventional osteosarcoma. Due to nonspecific symptoms, most osteosarcomas of the jaws are misdiagnosed as periapical abscesses and mistreated by teeth extraction and drainage.
    Case presentation: We report, to our knowledge, the seventh case of small cell osteosarcoma in gnathic sites affecting the mandible of an old female with history of a large painful swelling related to the right mandibular molar area for 2 months. Cone-beam computed tomography scan showed an osteolytic lesion related to the lower molar area with involvement of the inferior alveolar nerve. An incisional biopsy was taken, and after histopathological examination and immunohistochemical staining, a diagnosis of small cell osteosarcoma was reached. Hemi-mandibulectomy was performed by a maxillofacial surgeon. No clinical evidence for recurrence was noted until manuscript writing.
    Conclusion: Accurate diagnosis is very important, and general practitioners should be aware of this entity considering that small cell osteosarcoma has a poor prognosis when compared to conventional osteosarcoma.
    MeSH term(s) Female ; Humans ; Mandible/diagnostic imaging ; Mandible/surgery ; Mandibular Osteotomy ; Biopsy ; Osteosarcoma/diagnostic imaging ; Osteosarcoma/surgery ; Bone Neoplasms/diagnostic imaging
    Language English
    Publishing date 2023-09-18
    Publishing country England
    Document type Review ; Case Reports ; Journal Article
    ZDB-ID 1176790-x
    ISSN 2589-0409 ; 1110-0362
    ISSN (online) 2589-0409
    ISSN 1110-0362
    DOI 10.1186/s43046-023-00191-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3918: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Oral carcinoma cuniculatum: an unacquainted entity with diagnostic challenges-a case report.

    Baz, Safaa / Amer, Hatem Wael / Wahed, Ali A

    Journal of the Egyptian National Cancer Institute

    2022  Volume 34, Issue 1, Page(s) 3

    Abstract: Background: Oral carcinoma cuniculatum (OCC) is an unacquainted well-differentiated subtype of oral squamous cell carcinoma, which displays unique clinic-pathological features. Up to date, OCC remains rare with about 75 reported cases, and is frequently ...

    Abstract Background: Oral carcinoma cuniculatum (OCC) is an unacquainted well-differentiated subtype of oral squamous cell carcinoma, which displays unique clinic-pathological features. Up to date, OCC remains rare with about 75 reported cases, and is frequently missed or even misdiagnosed.
    Case presentation: The aim of the present work was: to report a case of OCC in mandibular gingiva and to highlight its main clinic-pathological diagnostic features: with an exophytic cobble-stone surface and a characteristic endophytic burrowing architecture, as well as to differentiate between it and other closely similar lesions including verrucous carcinoma, papillary squamous cell carcinoma, and well-differentiated conventional oral squamous cell carcinoma.
    Conclusions: An accurate diagnosis of OCC entails awareness of the clinicians and pathologists about its entity, proper knowledge of the diagnostic clinical and histopathological evidence, and the ability to differentiate it from closely similar lesions.
    MeSH term(s) Carcinoma, Squamous Cell/diagnosis ; Carcinoma, Verrucous/diagnosis ; Head and Neck Neoplasms ; Humans ; Mouth Neoplasms/diagnosis ; Squamous Cell Carcinoma of Head and Neck
    Language English
    Publishing date 2022-01-17
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 1176790-x
    ISSN 2589-0409 ; 1110-0362
    ISSN (online) 2589-0409
    ISSN 1110-0362
    DOI 10.1186/s43046-021-00101-4
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    Zs.A 3918: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Maximizing Solid Organ and Face Transplant Procurement Team Coordination: The Posterior Tibial Artery Flap as an Ideal Sentinel Flap.

    Suchyta, Marissa A / Carlsen, Brian / Bakri, Karim / Amer, Hatem / Mardini, Samir

    Mayo Clinic proceedings. Innovations, quality & outcomes

    2023  Volume 7, Issue 4, Page(s) 244–247

    Abstract: Face transplantation became a reality with the first case performed in 2005. Facial tissue allograft procurement is technically complex and time-intensive. Brain-dead deceased donors are frequently, if not always, multiorgan donors. Every effort should ... ...

    Abstract Face transplantation became a reality with the first case performed in 2005. Facial tissue allograft procurement is technically complex and time-intensive. Brain-dead deceased donors are frequently, if not always, multiorgan donors. Every effort should be made during face allograft recovery to minimize any risk to the recovery of lifesaving solid organs. Some programs require the procurement of a myofascial vascularized skin graft to function as a sentinel flap allowing frequent monitoring for rejection without negatively impacting the esthetics of the face graft. Up till now, the flap used has been the radial forearm flap. Procuring the radial forearm flap places the procuring team in close proximity to the head and torso, where the face recovery and the solid organ recovery teams would require unhindered access. Here, we present the posterior tibial artery flap as an alternative flap that would provide benefits to the coordination of the multiple teams working to procure organs from a deceased donor.
    Language English
    Publishing date 2023-06-07
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2542-4548
    ISSN (online) 2542-4548
    DOI 10.1016/j.mayocpiqo.2022.04.006
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  8. Article ; Online: Has Noninvasive Kidney Transplant Surveillance Finally Arrived?

    Meeusen, Jeffrey W / Amer, Hatem / Lieske, John C

    Clinical chemistry

    2021  Volume 67, Issue 8, Page(s) 1047–1049

    MeSH term(s) Biomarkers ; Graft Rejection ; Humans ; Kidney ; Kidney Transplantation ; Metabolomics
    Chemical Substances Biomarkers
    Language English
    Publishing date 2021-08-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 80102-1
    ISSN 1530-8561 ; 0009-9147
    ISSN (online) 1530-8561
    ISSN 0009-9147
    DOI 10.1093/clinchem/hvab015
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    Ud II Zs.171: Show issues Location:
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  9. Article ; Online: Mitigating Risk of Immunosuppression by Immune Monitoring: Are We There?

    Bentall, Andrew / Amer, Hatem

    Transplantation

    2018  Volume 102, Issue 3, Page(s) 349–350

    MeSH term(s) Graft Rejection/immunology ; Immune Tolerance ; Immunosuppression ; Monitoring, Immunologic
    Language English
    Publishing date 2018-01-10
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 208424-7
    ISSN 1534-6080 ; 0041-1337
    ISSN (online) 1534-6080
    ISSN 0041-1337
    DOI 10.1097/TP.0000000000002037
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    Zs.A 488: Show issues Location:
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    Zs.MO 509: Show issues

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  10. Article ; Online: Facial Transplantation.

    Vyas, Krishna / Bakri, Karim / Gibreel, Waleed / Cotofana, Sebastian / Amer, Hatem / Mardini, Samir

    Facial plastic surgery clinics of North America

    2022  Volume 30, Issue 2, Page(s) 255–269

    Abstract: Facial transplantation is a vascularized composite allotransplantation, which may be considered in patients with extensive and challenging facial defects for which conventional reconstructive approaches fail to provide satisfactory functional and ... ...

    Abstract Facial transplantation is a vascularized composite allotransplantation, which may be considered in patients with extensive and challenging facial defects for which conventional reconstructive approaches fail to provide satisfactory functional and esthetic outcomes. Facial transplantation has the advantage of replacing defective or absent structures with anatomically identical tissues. Facial transplantation may provide functional, esthetic, and psychosocial benefits, but must be weighed against risks such as lifelong immunosuppression. Success is reliant on patient understanding, motivation, consent and compliance, and a multidisciplinary approach with careful team planning and organization. This review highlights the achievements, challenges, and future directions of this rapidly evolving field.
    MeSH term(s) Esthetics ; Face/surgery ; Facial Transplantation/psychology ; Forecasting ; Humans ; Reconstructive Surgical Procedures
    Language English
    Publishing date 2022-02-23
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1315178-2
    ISSN 1558-1926 ; 1064-7406
    ISSN (online) 1558-1926
    ISSN 1064-7406
    DOI 10.1016/j.fsc.2022.01.011
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