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  1. Article ; Online: Intracoronal tooth bleaching - A review and treatment guidelines.

    Amer, M

    Australian dental journal

    2023  Volume 68 Suppl 1, Page(s) S141–S152

    Abstract: Intracoronal bleaching is a minimally invasive procedure that was introduced into dentistry in the 19th century. The role of that procedure in enhancing the colour of teeth subjected to internal discolouration while being conservative made it extremely ... ...

    Abstract Intracoronal bleaching is a minimally invasive procedure that was introduced into dentistry in the 19th century. The role of that procedure in enhancing the colour of teeth subjected to internal discolouration while being conservative made it extremely popular amongst dental professionals. Different materials and techniques have been utilized over the years attempting to obtain predictable long-term results while minimizing any associated risks. Contemporarily, bleaching agents are mainly based on peroxide-releasing compounds in different formulations and delivery systems. Different theories have been formulated on the bleaching mechanism of such agents, but the exact mechanism is yet to be proven. The effect of hydrogen peroxide-based bleaching agents on the organic structure of enamel and dentine has been extensively investigated to address the effects of bonding of resin-based restorative materials to hard tooth structure. Multiple case reports raised a concern about the contribution of intracoronal bleaching in developing invasive root resorption. Modification of intracoronal bleaching techniques was thus necessary to address such concerns. This review will provide a summary of the important aspects of intracoronal bleaching, focusing on how it applies to the contemporary clinical setting. © 2023 Australian Dental Association.
    MeSH term(s) Humans ; Tooth Bleaching/methods ; Borates ; Australia ; Hydrogen Peroxide/therapeutic use ; Bleaching Agents
    Chemical Substances Borates ; Hydrogen Peroxide (BBX060AN9V) ; Bleaching Agents
    Language English
    Publishing date 2023-11-17
    Publishing country Australia
    Document type Journal Article ; Review
    ZDB-ID 603965-0
    ISSN 1834-7819 ; 0045-0421
    ISSN (online) 1834-7819
    ISSN 0045-0421
    DOI 10.1111/adj.13000
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    Zs.B 70: Show issues Location:
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  2. Article: Editorial: Impact of apathy on aging and age-related neuropsychiatric disorders.

    Burhan, Amer M

    Frontiers in psychiatry

    2023  Volume 14, Page(s) 1341182

    Language English
    Publishing date 2023-12-13
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2023.1341182
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  3. Article ; Online: Radiation protection for well logging operations in Saudi Arabia.

    Al-Somali, Omar / Amer, Mustafa

    Radiation protection dosimetry

    2023  Volume 199, Issue 8-9, Page(s) 911–914

    Abstract: In well logging, sophisticated tools are inserted into a borehole to measure physical and geological properties of rocks surrounding the well. Some of these, known as nuclear logging tools, contain radioactive sources and are used to obtain useful ... ...

    Abstract In well logging, sophisticated tools are inserted into a borehole to measure physical and geological properties of rocks surrounding the well. Some of these, known as nuclear logging tools, contain radioactive sources and are used to obtain useful information. When logging tools containing radioactive sources are inserted into the well, there is a risk that they may get stuck. If this occurs, a recovery operation, known as fishing, is used to attempt retrieval. If fishing fails to recover the radioactive sources, they are abandoned following an established protocol, which is in accordance with international, national and corporate standards, in addition to industry best practices. This paper provides an overview of radiation protection requirements for well logging operations in Saudi Arabia, to ensure the safety and security of radioactive sources, and the protection of workers and the public without impacting operational productivity.
    MeSH term(s) Humans ; Radiation Protection ; Saudi Arabia ; Geology ; Industry ; Physical Examination
    Language English
    Publishing date 2023-06-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 225912-6
    ISSN 1742-3406 ; 0144-8420
    ISSN (online) 1742-3406
    ISSN 0144-8420
    DOI 10.1093/rpd/ncad091
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  4. Article ; Online: Myelodysplastic Syndromes/Neoplasms-Insights Into Pathogenesis Leading to Improved Classification, Risk Stratification, and Treatments.

    Rose, Michal G / Zeidan, Amer M

    Cancer journal (Sudbury, Mass.)

    2023  Volume 29, Issue 3, Page(s) 109–110

    MeSH term(s) Humans ; Myelodysplastic Syndromes/diagnosis ; Myelodysplastic Syndromes/etiology ; Myelodysplastic Syndromes/therapy ; Prognosis ; Neoplasms ; Risk Assessment
    Language English
    Publishing date 2023-05-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2018400-1
    ISSN 1540-336X ; 1528-9117 ; 1081-4442
    ISSN (online) 1540-336X
    ISSN 1528-9117 ; 1081-4442
    DOI 10.1097/PPO.0000000000000663
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  5. Article ; Online: External validation of the Oakland Score to assess safe hospital discharge among adult patients with acute lower gastrointestinal bleeding in a single New Zealand Centre.

    Amer, Mostafa / Haddow, James Boyd

    ANZ journal of surgery

    2023  Volume 94, Issue 4, Page(s) 708–713

    Abstract: Background: Acute lower gastrointestinal bleeding (LGIB) is a common reason for hospital admission. However, the majority resolve spontaneously and only a minority require inpatient intervention. We aimed to describe the epidemiology and aetiology of ... ...

    Abstract Background: Acute lower gastrointestinal bleeding (LGIB) is a common reason for hospital admission. However, the majority resolve spontaneously and only a minority require inpatient intervention. We aimed to describe the epidemiology and aetiology of acute LGIB admissions in our institution. We also aimed to validate the Oakland Score, which can identify patients at low risk of adverse outcome from LGIB, in our population and determine the proportion who could have safely avoided admission.
    Methods: Using the prospective, validated Otago Clinical Audit database (DIVA), we searched for adult patients admitted to Dunedin Hospital with a primary diagnosis of LGIB between January 2013 and December 2020. We retrieved data to calculate the Oakland Score and details of inpatient treatment from the electronic patient record. We excluded patients admitted electively, admissions related to inflammatory bowel disease, and those with upper gastrointestinal bleeding.
    Results: We identified 761 patients of which 501 met inclusion criteria (56% male, median age 76 years, 82% NZ European). Overall, 72% were managed with observation or diagnostic endoscopy, 32% received blood products, and 7% required haemostatic intervention to control bleeding. The area under the receiver operating characteristic curve for the Oakland Score was 0.85 (95% CI, 0.81-0.89). A cut-off score of ≤10 predicted a 95% probability of safely avoiding admission. This equates to saving 30 bed-days annually.
    Conclusion: The majority of patients admitted with LGIB are managed conservatively. The Oakland Score could be used as a stratification tool to safely reduce the admission rate.
    MeSH term(s) Adult ; Humans ; Male ; Aged ; Female ; Patient Discharge ; Prospective Studies ; New Zealand/epidemiology ; Risk Assessment ; Gastrointestinal Hemorrhage/diagnosis ; Gastrointestinal Hemorrhage/epidemiology ; Gastrointestinal Hemorrhage/etiology ; Acute Disease ; Hospitals ; Retrospective Studies
    Language English
    Publishing date 2023-12-07
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2050749-5
    ISSN 1445-2197 ; 1445-1433 ; 0004-8682
    ISSN (online) 1445-2197
    ISSN 1445-1433 ; 0004-8682
    DOI 10.1111/ans.18813
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    Zs.A 180: Show issues Location:
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  6. Article ; Online: Development of an Online Cardiovascular Pre-participation Screening Tool: The Community and Athletic Cardiovascular Health Network Screening Portal.

    Grubic, Nicholas / Johri, Amer M

    The Canadian journal of cardiology

    2023  Volume 39, Issue 7, Page(s) 883–885

    MeSH term(s) Humans ; Sports ; Cardiovascular System ; Heart ; Mass Screening
    Language English
    Publishing date 2023-03-13
    Publishing country England
    Document type Editorial ; Research Support, Non-U.S. Gov't
    ZDB-ID 632813-1
    ISSN 1916-7075 ; 0828-282X
    ISSN (online) 1916-7075
    ISSN 0828-282X
    DOI 10.1016/j.cjca.2023.03.008
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    Zs.A 2150: Show issues Location:
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  7. Article ; Online: Treatment Considerations of Myelodysplastic Syndromes/Neoplasms for Pathologists.

    Madanat, Yazan F / Zeidan, Amer M

    Clinics in laboratory medicine

    2023  Volume 43, Issue 4, Page(s) 685–698

    Abstract: The diagnosis of myelodysplastic syndromes/neoplasms (MDS) has evolved over the years with the incorporation of genetic abnormalities to establish a diagnosis, their impact on risk stratification, prognostication, and therapeutic options. ... ...

    Abstract The diagnosis of myelodysplastic syndromes/neoplasms (MDS) has evolved over the years with the incorporation of genetic abnormalities to establish a diagnosis, their impact on risk stratification, prognostication, and therapeutic options. Hematopathologists are the cornerstone to establish an accurate diagnosis and ensure patients receive the best available treatment option. Hematopathologists and clinicians must work closely together to establish the best disease subclassification, by combining pathologic findings with the clinical presentation. This will ensure patients receive the best therapeutic approach by better understanding the disease entity. In this review, we discuss how we approach a bone marrow biopsy report in the management of MDS.
    MeSH term(s) Humans ; Prognosis ; Pathologists ; Neoplasms ; Myelodysplastic Syndromes/diagnosis ; Myelodysplastic Syndromes/therapy
    Language English
    Publishing date 2023-08-08
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 604580-7
    ISSN 1557-9832 ; 0272-2712
    ISSN (online) 1557-9832
    ISSN 0272-2712
    DOI 10.1016/j.cll.2023.07.003
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    Zs.A 1695: Show issues Location:
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  8. Article ; Online: The Application of Point of Care Ultrasound to Screen for Pulmonary Hypertension: A Narrative Review.

    Ke, Danny Yu Jia / Tso, Melissa / Johri, Amer M

    POCUS journal

    2024  Volume 9, Issue 1, Page(s) 109–116

    Abstract: Background: Pulmonary Hypertension (PH) is a condition with several cardiopulmonary etiologies that has the potential of progressing to right heart failure without proper intervention. After a history, physical exam, and investigations, cases of ... ...

    Abstract Background: Pulmonary Hypertension (PH) is a condition with several cardiopulmonary etiologies that has the potential of progressing to right heart failure without proper intervention. After a history, physical exam, and investigations, cases of suspected PH typically undergo imaging via a transthoracic echocardiogram (TTE). This is a resource-intensive procedure that is less accessible in remote communities. However, point of care ultrasound (POCUS), a portable ultrasound administered at the bedside, has potential to aid in the diagnostic process of PH.
    Methods: The MEDLINE, Embase, and CENTRAL databases were searched to screen the intersection of POCUS and PH. Studies involved adult patients, and only English articles were accepted. Reviews, case reports, unfinished research, and conference abstracts were excluded. Our aim was to identify primary studies that correlated POCUS scan results and additional clinical findings related to PH.
    Results: Nine studies were included after our search. In these studies, POCUS was effective in identifying dilatation of inferior vena cava (IVC); internal jugular vein (IJV); and hepatic, portal, and intrarenal veins in patients with PH. The presence of pericardial effusion, pleural effusion, or b-lines on POCUS are also associated with PH.
    Conclusions: This review suggests important potential for the use of POCUS in the initial screening of PH. IVC and basic cardiopulmonary POCUS exams are key for PH screening in patients with dyspnea. Right-heart dilatation can be visualized, and peripheral veins may be scanned based on clinical suspicion. POCUS offers screening as an extension of a physical exam, with direct visualization of cardiac morphology. However, more studies are required to develop a statistically validated POCUS exam for PH diagnosis. More studies should also be conducted at the primary-care level to evaluate the value of screening using POCUS for PH in less-differentiated patients.
    Language English
    Publishing date 2024-04-22
    Publishing country Canada
    Document type Journal Article ; Review
    ISSN 2369-8543
    ISSN (online) 2369-8543
    DOI 10.24908/pocus.v9i1.17494
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  9. Article ; Online: Recanalized Falcine Sinus.

    Mandel, Daniel M / Crenesse-Cozien, Natalia / Malik, Amer M

    Stroke

    2024  Volume 55, Issue 5, Page(s) e136–e137

    Language English
    Publishing date 2024-03-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80381-9
    ISSN 1524-4628 ; 0039-2499 ; 0749-7954
    ISSN (online) 1524-4628
    ISSN 0039-2499 ; 0749-7954
    DOI 10.1161/STROKEAHA.124.046777
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  10. Article ; Online: Potential therapeutic role of microvesicles derived from mesenchymal stem cells and platelet-rich plasma in murine burn wound healing: scar regulation and antioxidant mechanism.

    Imam, R A / Amer, M M

    Folia morphologica

    2022  Volume 82, Issue 3, Page(s) 656–667

    Abstract: Background: Microvesicles (MVs) derived from mesenchymal stem cells exhibited an emerging promising therapy in many animal model diseases. Post-burn scars represent one of the significant challenges in wound healing processes. The present study ... ...

    Abstract Background: Microvesicles (MVs) derived from mesenchymal stem cells exhibited an emerging promising therapy in many animal model diseases. Post-burn scars represent one of the significant challenges in wound healing processes. The present study investigated the possible role of MVs derived from mesenchymal stem cells vs. platelet-rich plasma (PRP) in murine burn wound healing.
    Materials and methods: Wistar rats (n = 40) were assigned into four equal groups (control, burn, burn + PRP, burn + MVs). Small-sized burns were induced, morphologically followed for 3 weeks, then rats were sacrificed and skin lesions were analysed biochemically and immunohistochemically.
    Results: Both MVs and PRP modulated the burn healing process with better results in the MVs group than in PRP. MVs significantly (p < 0.05) accelerated burn wound size healing and dramatically modulated tissue interleukin (IL)-10, IL-6, and hyaluronidase. Both MVs and PRP significantly downregulated gene expression of miRNA203 and alpha smooth muscle actin and immunoblotting analysis of matrix metalloproteinases 3 and transforming growth factor beta compared with the burn group. The immune-staining intensity of tumour necrosis factor alpha was dramatically reversed in the MVs group compared with the burn group, whereas that of connective tissue growth factor, collagen I and III was significantly reduced in both groups. The antioxidant Nrf2 immune-staining intensity had been dramatically enhanced particularly in MVs.
    Conclusions: Microvesicles derived from mesenchymal stem cells and PRP may improve burn wound healing via regulating scar formation and antioxidant mechanism.
    MeSH term(s) Mice ; Rats ; Animals ; Cicatrix/therapy ; Cicatrix/metabolism ; Antioxidants/metabolism ; Rats, Wistar ; Wound Healing ; Platelet-Rich Plasma ; Mesenchymal Stem Cells ; MicroRNAs/metabolism
    Chemical Substances Antioxidants ; MIRN203 microRNA, rat ; MicroRNAs
    Language English
    Publishing date 2022-06-27
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 419361-1
    ISSN 1644-3284 ; 0015-5659
    ISSN (online) 1644-3284
    ISSN 0015-5659
    DOI 10.5603/FM.a2022.0060
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