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  1. Book ; Thesis: Liver transplantation during infancy

    Ameres, Markus

    no increased rate of neurological complications

    2019  

    Author's details vorgelegt von Markus Ameres
    Subject code 610
    Language English ; German
    Size 10, [7] Blätter, Illustrationen, 21 cm
    Publishing place Regensburg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Universität Regensburg, 2020
    Note Enthält Originalartikel; Fragestellung und Erläuterungen in deutscher Sprache
    HBZ-ID HT020605460
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2020 D 735 order for loan Magazin

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  2. Book ; Thesis: Etablierung und Validierung eines prognoseorientierten Tumor-Gewebe-Arrays maligner Melanome

    Ameres, Markus

    2006  

    Author's details vorgelegt von Markus Ameres
    Language German
    Size 70, [23] Bl. : Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Regensburg, Univ., Diss., 2007
    HBZ-ID HT015139388
    Database Catalogue ZB MED Medicine, Health

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    2007 D 746 order for loan Magazin

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  3. Article ; Conference proceedings: Neurological Complications after Liver Transplantation during Infancy

    Ameres, Markus / Melter, Michael / Schilling, Stefan / Geis, Tobias

    Neuropediatrics

    2019  Volume 50, Issue S 02

    Event/congress Abstracts of the 45th Annual Meeting of the Society for Neuropediatrics, München, 2019-09-11
    Language English
    Publishing date 2019-09-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 573291-8
    ISSN 1439-1899 ; 0174-304X
    ISSN (online) 1439-1899
    ISSN 0174-304X
    DOI 10.1055/s-0039-1698260
    Database Thieme publisher's database

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  4. Article ; Online: Liver transplantation during infancy: No increased rate of neurological complications.

    Ameres, Markus / Melter, Michael / Zant, Robert / Schilling, Stefan / Geis, Tobias

    Pediatric transplantation

    2018  Volume 22, Issue 8, Page(s) e13304

    Abstract: pLT is a highly standardized therapy for children with end-stage liver disease and liver-based metabolic diseases. However, NCs after transplantation occur and especially younger children are considered as more vulnerable and susceptible to NCs. Up to ... ...

    Abstract pLT is a highly standardized therapy for children with end-stage liver disease and liver-based metabolic diseases. However, NCs after transplantation occur and especially younger children are considered as more vulnerable and susceptible to NCs. Up to now, detailed data particularly for the very young age group do not exist. We therefore retrospectively studied NCs in children after pLT under age of 24 months. Forty children aged between 19 days and 22 months were evaluated according to type of NC and potential risk factors. NCs occurred in 8/40 patients (20%). All experienced new-onset seizures and in 1/6 surviving patients, seizures evolved into epilepsy. Other NCs were intracerebral abscess (1/8 patients) and subdural hemorrhage (1/8 patients). The overall 3-year mortality rate was 10% (4/40 patients). Significant risk factors for NCs and therefore seizures were HAT (P = 0.020), total surgery time (P = 0.009), retransplantation (P < 0.001), period of catecholamine therapy (P = 0.024), period of mechanical ventilation (P = 0.014), and period of sedation (P = 0.010). Our study is the first to provide detailed information on NCs after pLT in children under 24 months of age. The incidence of NCs in this particular group of very young patients was not increased compared to previously published data of children of all ages. Main NC was new-onset seizure. In the surviving infants, prognosis of seizure was excellent and the risk of developing epilepsy was low. Even more, the occurrence of NCs did not significantly affect mortality or survival in this particular age group.
    MeSH term(s) Brain Abscess/complications ; Catecholamines/therapeutic use ; End Stage Liver Disease/complications ; End Stage Liver Disease/surgery ; Epilepsy ; Female ; Hematoma, Subdural/complications ; Humans ; Incidence ; Infant ; Infant, Newborn ; Liver Transplantation/adverse effects ; Male ; Nervous System Diseases/complications ; Respiration, Artificial ; Retrospective Studies ; Risk Factors ; Seizures/complications
    Chemical Substances Catecholamines
    Language English
    Publishing date 2018-10-12
    Publishing country Denmark
    Document type Journal Article
    ZDB-ID 1390284-2
    ISSN 1399-3046 ; 1397-3142
    ISSN (online) 1399-3046
    ISSN 1397-3142
    DOI 10.1111/petr.13304
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4947: Show issues Location:
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  5. Article ; Online: Association of neuronal injury blood marker neurofilament light chain with mild-to-moderate COVID-19.

    Ameres, Markus / Brandstetter, Susanne / Toncheva, Antoaneta A / Kabesch, Michael / Leppert, David / Kuhle, Jens / Wellmann, Sven

    Journal of neurology

    2020  Volume 267, Issue 12, Page(s) 3476–3478

    MeSH term(s) Adolescent ; Adult ; Aged ; Biomarkers/blood ; COVID-19 ; Coronavirus Infections/complications ; Female ; Health Personnel ; Humans ; Male ; Middle Aged ; Nervous System Diseases/blood ; Nervous System Diseases/etiology ; Neurofilament Proteins/blood ; Pandemics ; Pneumonia, Viral/complications ; Prospective Studies ; Respiration Disorders/etiology ; Severity of Illness Index ; Young Adult
    Chemical Substances Biomarkers ; Neurofilament Proteins ; neurofilament protein L
    Keywords covid19
    Language English
    Publishing date 2020-07-09
    Publishing country Germany
    Document type Letter
    ZDB-ID 187050-6
    ISSN 1432-1459 ; 0340-5354 ; 0012-1037 ; 0939-1517 ; 1619-800X
    ISSN (online) 1432-1459
    ISSN 0340-5354 ; 0012-1037 ; 0939-1517 ; 1619-800X
    DOI 10.1007/s00415-020-10050-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Association of neuronal injury blood marker neurofilament light chain with mild-to-moderate COVID-19

    Ameres, Markus / Brandstetter, Susanne / Toncheva, Antoaneta A / Kabesch, Michael / Leppert, David / Kuhle, Jens / Wellmann, Sven

    J. neurol

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #636081
    Database COVID19

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  7. Article ; Online: Association of neuronal injury blood marker neurofilament light chain with mild-to-moderate COVID-19

    Ameres, Markus / Brandstetter, Susanne / Toncheva, Antoaneta A. / Kabesch, Michael / Leppert, David / Kuhle, Jens / Wellmann, Sven

    Journal of Neurology ; ISSN 0340-5354 1432-1459

    2020  

    Keywords Neurology ; Clinical Neurology ; covid19
    Language English
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    DOI 10.1007/s00415-020-10050-y
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Tissue microarray analysis of methylthioadenosine phosphorylase protein expression in melanocytic skin tumors.

    Wild, Peter J / Meyer, Stefanie / Bataille, Frauke / Woenckhaus, Matthias / Ameres, Markus / Vogt, Thomas / Landthaler, Michael / Pauer, Armin / Klinkhammer-Schalke, Monika / Hofstaedter, Ferdinand / Bosserhoff, Anja K

    Archives of dermatology

    2006  Volume 142, Issue 4, Page(s) 471–476

    Abstract: Background: Using tissue microarrays, we investigated whether methylthioadenosine phosphorylase (MTAP) protein expression is associated with clinicopathologic variables in benign and malignant melanocytic skin tumors.: Observations: Cytoplasmic MTAP ... ...

    Abstract Background: Using tissue microarrays, we investigated whether methylthioadenosine phosphorylase (MTAP) protein expression is associated with clinicopathologic variables in benign and malignant melanocytic skin tumors.
    Observations: Cytoplasmic MTAP expression was detected in 227 (72.1%) of 315 informative cases. Expression was significantly reduced in primary malignant melanomas and in melanoma metastases compared with benign nevi (P<.001 for both). No difference was noted in MTAP expression between primary malignant melanomas and melanoma metastases. In primary malignant melanomas, a Ki67-labeling index less than 5% was associated with MTAP expression (P = .04), suggesting that loss of MTAP expression is associated with proliferation. No other variables had significant associations with MTAP expression. Lymph node metastases demonstrated significantly higher MTAP expression compared with skin metastases (P = .01). In the overall cohort, MTAP expression was not associated with prognosis. Among 26 patients with MTAP-positive melanomas and tumor recurrence, 18 patients who received interferon therapy had a significant benefit compared with 8 patients who did not receive interferon therapy (P = .009). This was not seen in the patients with MTAP-negative tumors. Conclusion Methylthioadenosine phosphorylase protein expression may be a predictive marker of interferon therapy resistance in patients with melanoma and disease progression.
    MeSH term(s) Antineoplastic Agents/therapeutic use ; Case-Control Studies ; Disease-Free Survival ; Drug Resistance, Neoplasm ; Female ; Germany/epidemiology ; Humans ; Immunohistochemistry ; Interferons/therapeutic use ; Male ; Melanoma/drug therapy ; Melanoma/metabolism ; Melanoma/mortality ; Microarray Analysis ; Middle Aged ; Neoplasm Metastasis ; Neoplasm Recurrence, Local/drug therapy ; Neoplasm Recurrence, Local/metabolism ; Neoplasm Recurrence, Local/mortality ; Prognosis ; Purine-Nucleoside Phosphorylase/metabolism ; Skin Neoplasms/drug therapy ; Skin Neoplasms/metabolism ; Skin Neoplasms/mortality ; Survival Analysis
    Chemical Substances Antineoplastic Agents ; Interferons (9008-11-1) ; Purine-Nucleoside Phosphorylase (EC 2.4.2.1) ; 5'-methylthioadenosine phosphorylase (EC 2.4.2.28)
    Language English
    Publishing date 2006-04
    Publishing country United States
    Document type Evaluation Studies ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 212139-6
    ISSN 1538-3652 ; 0003-987X
    ISSN (online) 1538-3652
    ISSN 0003-987X
    DOI 10.1001/archderm.142.4.471
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