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  1. Article ; Online: Letter to the editor regarding "Surgical site infection a major risk factor of pseudarthrosis in adult spinal deformity surgery" by Boishardy et al.

    Mazhar, Fariha / Amin Muhammad, Alina

    The spine journal : official journal of the North American Spine Society

    2023  Volume 23, Issue 5, Page(s) 783

    MeSH term(s) Humans ; Adult ; Surgical Wound Infection/epidemiology ; Surgical Wound Infection/etiology ; Pseudarthrosis/etiology ; Pseudarthrosis/surgery ; Risk Factors ; Neurosurgical Procedures ; Spinal Fusion/adverse effects
    Language English
    Publishing date 2023-02-10
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2037072-6
    ISSN 1878-1632 ; 1529-9430
    ISSN (online) 1878-1632
    ISSN 1529-9430
    DOI 10.1016/j.spinee.2023.01.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5898: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
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  2. Article: A Rare Case of Salmonella Gastroenteritis Presenting as Aspiration Pneumonia With Pleural Empyema in an Immunocompetent Patient.

    Mehmood, Asif / Amin, Muhammad Fahad

    Cureus

    2023  Volume 15, Issue 4, Page(s) e37192

    Abstract: Non-typhoidal salmonella (NTS) can cause infections ranging from self-limited chronic carriers to gastroenteritis, bacteremia, and extraintestinal infections. Pulmonary involvement, particularly empyema, is quite rare and generally found in ... ...

    Abstract Non-typhoidal salmonella (NTS) can cause infections ranging from self-limited chronic carriers to gastroenteritis, bacteremia, and extraintestinal infections. Pulmonary involvement, particularly empyema, is quite rare and generally found in immunosuppressed individuals. We present a case of salmonellosis in an immunocompetent patient with rare pulmonary complications of empyema. The patient, with no underlying immunocompromised illness, presented with a one-day history of worsening generalized weakness, fever, shortness of breath, and productive cough after having gastroenteritis symptoms of five days duration, which stopped two days prior to admission. On further investigation, imaging revealed right lower lobe pneumonia with empyema. The patient was managed with intravenous antibiotics and chest tube placement with good clinical response. Pleural fluid analysis showed exudative fluid and grew
    Language English
    Publishing date 2023-04-06
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.37192
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: FabNet: A Features Agglomeration-Based Convolutional Neural Network for Multiscale Breast Cancer Histopathology Images Classification.

    Amin, Muhammad Sadiq / Ahn, Hyunsik

    Cancers

    2023  Volume 15, Issue 4

    Abstract: The definitive diagnosis of histology specimen images is largely based on the radiologist's comprehensive experience; however, due to the fine to the coarse visual appearance of such images, experts often disagree with their assessments. Sophisticated ... ...

    Abstract The definitive diagnosis of histology specimen images is largely based on the radiologist's comprehensive experience; however, due to the fine to the coarse visual appearance of such images, experts often disagree with their assessments. Sophisticated deep learning approaches can help to automate the diagnosis process of the images and reduce the analysis duration. More efficient and accurate automated systems can also increase the diagnostic impartiality by reducing the difference between the operators. We propose a FabNet model that can learn the fine-to-coarse structural and textural features of multi-scale histopathological images by using accretive network architecture that agglomerate hierarchical feature maps to acquire significant classification accuracy. We expand on a contemporary design by incorporating deep and close integration to finely combine features across layers. Our deep layer accretive model structure combines the feature hierarchy in an iterative and hierarchically manner that infers higher accuracy and fewer parameters. The FabNet can identify malignant tumors from images and patches from histopathology images. We assessed the efficiency of our suggested model standard cancer datasets, which included breast cancer as well as colon cancer histopathology images. Our proposed avant garde model significantly outperforms existing state-of-the-art models in respect of the accuracy, F1 score, precision, and sensitivity, with fewer parameters.
    Language English
    Publishing date 2023-02-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers15041013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Impact of aortic valve disease on outcomes of aortic root replacement.

    Amin Muhammad, Alina / Kumar, Satesh / Khatri, Mahima

    Journal of cardiac surgery

    2022  

    Language English
    Publishing date 2022-10-02
    Publishing country United States
    Document type Letter
    ZDB-ID 639059-6
    ISSN 1540-8191 ; 0886-0440
    ISSN (online) 1540-8191
    ISSN 0886-0440
    DOI 10.1111/jocs.16989
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2221: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: New ridge parameter estimators for the quasi-Poisson ridge regression model.

    Shahzad, Aamir / Amin, Muhammad / Emam, Walid / Faisal, Muhammad

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 8489

    Abstract: The quasi-Poisson regression model is used for count data and is preferred over the Poisson regression model in the case of over-dispersed count data. The quasi-likelihood estimator is used to estimate the regression coefficients of the quasi-Poisson ... ...

    Abstract The quasi-Poisson regression model is used for count data and is preferred over the Poisson regression model in the case of over-dispersed count data. The quasi-likelihood estimator is used to estimate the regression coefficients of the quasi-Poisson regression model. The quasi-likelihood estimator gives sub-optimal estimates if regressors are highly correlated-multicollinearity issue. Biased estimation methods are often used to overcome the multicollinearity issue in the regression model. In this study, we explore the ridge estimator for the quasi-Poisson regression model to mitigate the multicollinearity issue. Furthermore, we propose various ridge parameter estimators for this model. We derive the theoretical properties of the ridge estimator and compare its performance with the quasi-likelihood estimator in terms of matrix and scalar mean squared error. We further compared the proposed estimator numerically through a Monte Carlo simulation study and a real-life application. We found that both the simulation and application results show the superiority of the ridge estimator, particularly with the best ridge parameter estimator, over the quasi-likelihood estimator in the presence of multicollinearity issue.
    Language English
    Publishing date 2024-04-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-50085-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Enhancing Stability and Mucoadhesive Properties of Chitosan Nanoparticles by Surface Modification with Sodium Alginate and Polyethylene Glycol for Potential Oral Mucosa Vaccine Delivery.

    Amin, Muhammad Khairul / Boateng, Joshua Siaw

    Marine drugs

    2022  Volume 20, Issue 3

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Adhesiveness ; Administration, Oral ; Alginates/chemistry ; Animals ; Antigens/chemistry ; Chitosan/chemistry ; Drug Carriers/chemistry ; Drug Liberation ; Drug Stability ; Gastric Juice/chemistry ; Intestinal Secretions/chemistry ; Mouth Mucosa ; Mucins/chemistry ; Nanoparticles/chemistry ; Ovalbumin/chemistry ; Polyethylene Glycols/chemistry ; Surface Properties ; Swine ; Vaccines/chemistry
    Chemical Substances Alginates ; Antigens ; Drug Carriers ; Mucins ; Vaccines ; Polyethylene Glycols (3WJQ0SDW1A) ; Ovalbumin (9006-59-1) ; Chitosan (9012-76-4)
    Language English
    Publishing date 2022-02-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175190-0
    ISSN 1660-3397 ; 1660-3397
    ISSN (online) 1660-3397
    ISSN 1660-3397
    DOI 10.3390/md20030156
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Surface functionalization of PLGA nanoparticles for potential oral vaccine delivery targeting intestinal immune cells.

    Amin, Muhammad Khairul / Boateng, Joshua

    Colloids and surfaces. B, Biointerfaces

    2022  Volume 222, Page(s) 113121

    Abstract: This study aimed to develop surface modified PLGA nanocarriers protecting a protein-based antigen in the stomach to enable potential release of the antigen at target intestinal sites. PLGA nanoparticles (NPs) were prepared by double emulsion and solvent ... ...

    Abstract This study aimed to develop surface modified PLGA nanocarriers protecting a protein-based antigen in the stomach to enable potential release of the antigen at target intestinal sites. PLGA nanoparticles (NPs) were prepared by double emulsion and solvent evaporation techniques while surface functionalization was performed using polyethylene glycol (PEG), sodium alginate (ALG) and Eudragit L100 (EUD) with ovalbumin (OVA) as a model protein antigen. Nanoparticles were characterized by dynamic light scattering (DLS), scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy (FTIR), gel permeation chromatography (GPC), and stability in simulated gastric fluid (SGF)/simulated intestinal fluid (SIF). Structural integrity of released OVA was analyzed by circular dichroism (CD) and sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE), while cytotoxicity against Jurkat cells was determined using MTT assay. Surface functionalized PLGA NPs protected the protein in SGF and SIF better than the non-functionalized NPs. Average size of OVA encapsulated NPs was between 235 and 326 nm and were spherical. FTIR band change was observed after surface modification and the surface modified NPs showed sustained OVA release compared with the uncoated NPs. The secondary structure of OVA released after 96 h remained intact and MTT assay showed >80 % cell viability after 72 h while unmodified and surface modified NPs achieved 17 % and 48 % mucin binding respectively. In conclusion, surface modified PLGA NPs have been shown to be safe for potential oral protein-based vaccine delivery.
    MeSH term(s) Humans ; Drug Delivery Systems ; Antigens/chemistry ; Alginates/chemistry ; Ovalbumin/chemistry ; Vaccines ; Nanoparticles/chemistry ; Drug Carriers/chemistry ; Particle Size
    Chemical Substances Antigens ; Alginates ; Ovalbumin (9006-59-1) ; Vaccines ; Drug Carriers
    Language English
    Publishing date 2022-12-29
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1500523-9
    ISSN 1873-4367 ; 0927-7765
    ISSN (online) 1873-4367
    ISSN 0927-7765
    DOI 10.1016/j.colsurfb.2022.113121
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Sustainable waste management and waste-to-energy in the context of a circular economy through various waste management technologies.

    Shah, Hamad Hussain / Amin, Muhammad / Pepe, Francesco / Tregambi, Claudio

    Environmental science and pollution research international

    2024  

    Abstract: Inappropriate waste management is a considerable ecological risk, leading to detrimental effects on the soil, air, and water quality. It is imperative to address these concerns promptly to minimize the repercussions of solid waste on public health and ... ...

    Abstract Inappropriate waste management is a considerable ecological risk, leading to detrimental effects on the soil, air, and water quality. It is imperative to address these concerns promptly to minimize the repercussions of solid waste on public health and the ecosystem. It is evident that the level of economic growth directly impacts waste generation. This study intends to use the life cycle assessment (LCA) technique to evaluate the environmental impacts of four alternative municipal solid waste (MSW) management scenarios in Peshawar City, Pakistan. The goal is to discover an option that is both sustainable and minimizes environmental damage. The study examined the system boundaries encompassing the collection and transportation of MSW, along with its processing and final disposal, employing composting, anaerobic digestion (AD), material recovery facilities (MRF), and landfill methods. Comprehensive field studies and an in-depth literature review provided the data regarding Peshawar's existing MSW management system and the proposed scenarios, all of which was inventoried in the OpenLCA 1.10.3 database. Following data collection, the CML-IA technique was employed to analyze the data, measuring the environmental footprint in terms of climate change potential, human toxicity, acidification potential, photochemical oxidation, and eutrophication. A sensitivity analysis was also performed to identify the influence of varying recycling rates on the environmental strain correlated with the proposed scenarios. The analysis results indicated that scenario S2, which combined composting, landfilling, and MRF, exhibited the least environmental impact compared to the other considered scenarios. Furthermore, the sensitivity analysis reflected an inverse correlation between alterations in the recycling rate and the total environmental impact. To counter the environmental problems arising from waste generation, it is essential to incorporate principles of the circular economy into the MSW management approach.
    Language English
    Publishing date 2024-04-08
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-024-33223-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 5915: Show issues

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  9. Article: False Positive Positron Emission Tomography/Computed Tomography (PET/CT) Requiring Biopsy for Proper Staging of Lung Cancer.

    Allen, Tanner / Hilu, John / Amin, Muhammad

    Cureus

    2023  Volume 15, Issue 2, Page(s) e34497

    Abstract: Lung cancer is the leading cause of cancer death in women in developed countries. Staging is crucial in determining the treatment modality. Different treatment modalities for lung cancer include surgery, radiation therapy, and chemotherapy. PET/CT is the ...

    Abstract Lung cancer is the leading cause of cancer death in women in developed countries. Staging is crucial in determining the treatment modality. Different treatment modalities for lung cancer include surgery, radiation therapy, and chemotherapy. PET/CT is the most sensitive and accurate modality for detecting hilar, mediastinal, and metastatic disease except in the brain. PET/CT scan often upstages the disease. PET/CT has also been shown to have false positive results. We present the case of a 72-year-old female who had a false positive finding on PET/CT, which would have changed the management process and outcome of her disease.
    Language English
    Publishing date 2023-02-01
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.34497
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: A short review on the role of thyroxine in fast wound healing and tissue regeneration.

    Amin, Muhammad Fahad / Zubair, Muhammad Sarmad / Ammar, Muhammad

    Tissue & cell

    2023  Volume 82, Page(s) 102115

    Abstract: Wound healing is a multiplex interaction process that involves extracellular matrix, blood vessels, proteases, cytokines, and chemokine. So far, a number of studies have been performed to understand the basis of the wound-healing process and multiple ... ...

    Abstract Wound healing is a multiplex interaction process that involves extracellular matrix, blood vessels, proteases, cytokines, and chemokine. So far, a number of studies have been performed to understand the basis of the wound-healing process and multiple wound-healing products have been designed. However, significant morbidity and mortality incidents still occurred due to poor wound healing. Thus, there is a dire need to understand the effects of topical applications of various therapeutic options that lead to fast wound healing. Thyroxine is one great panacea for wound healing that has been vigorously mooted throughout the years but a conclusive result regarding its effectiveness is still not achieved. This review is intended to find a rational basis for its positive role in wound healing. To accomplish the objective, this review highlights the different aspects of thyroxine's role in wound healing like keratin synthesis, skin thickening, and pro-angiogenesis, the basis of controversy on its wound healing ability and its potential to be used as a wound healing agent. This study will be helpful for researchers and surgeons to assess the importance of thyroxine as a candidate to comprehensively research to develop a potent, effective, and affordable wound healing drug.
    MeSH term(s) Thyroxine/pharmacology ; Wound Healing ; Extracellular Matrix ; Skin
    Chemical Substances Thyroxine (Q51BO43MG4)
    Language English
    Publishing date 2023-05-16
    Publishing country Scotland
    Document type Journal Article ; Review
    ZDB-ID 204424-9
    ISSN 1532-3072 ; 0040-8166
    ISSN (online) 1532-3072
    ISSN 0040-8166
    DOI 10.1016/j.tice.2023.102115
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1016: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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