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  1. Article ; Online: Payment Reform as a Means of Achieving Justice: A Look at Pulmonary Rehabilitation Reimbursement.

    Soled, Derek R / Thurber, Emilia / Amundson, Beret / Schissel, Scott Lew

    Chest

    2021  Volume 160, Issue 2, Page(s) 786–788

    MeSH term(s) Health Care Costs ; Humans ; Pulmonary Disease, Chronic Obstructive/rehabilitation ; Reimbursement Mechanisms ; Social Justice ; United States
    Language English
    Publishing date 2021-12-13
    Publishing country United States
    Document type Editorial
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2021.02.069
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ui III Zs.45: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 349: Show issues

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  2. Article ; Online: Cardiac troponin assays: a review of quantitative point-of-care devices and their efficacy in the diagnosis of myocardial infarction.

    Amundson, Beret E / Apple, Fred S

    Clinical chemistry and laboratory medicine

    2015  Volume 53, Issue 5, Page(s) 665–676

    Abstract: Cardiac troponin (cTn) I and T are released from myocardial cells following necrosis, i.e., cell death. An accurate measure of cTn concentrations in a patient's blood following ischemia/chest pain can enable providers to determine whether or not a ... ...

    Abstract Cardiac troponin (cTn) I and T are released from myocardial cells following necrosis, i.e., cell death. An accurate measure of cTn concentrations in a patient's blood following ischemia/chest pain can enable providers to determine whether or not a myocardial infarction (MI) has occurred. Point-of-care (POC) devices that measure blood cTn concentrations in under 30 min may help to significantly reduce hospital costs by managing and triaging patients out of the emergency department as quickly as possible. The use of POC devices that measure cTnI and cTnT with a coefficient of variation (CV) ≤20% at the 99th percentile upper reference limit (URL) limits both false positive and negative results and provides clinically acceptable findings to assist in appropriate diagnoses. This article reviews nine POC devices that measure cTn in terms of their clinical sensitivity and specificity, analytical imprecision, sample type and preparation, and each assay's principle of analysis.
    MeSH term(s) Clinical Chemistry Tests/instrumentation ; Device Approval ; Humans ; Myocardial Infarction/diagnosis ; Myocardial Infarction/metabolism ; Myocardium/metabolism ; Point-of-Care Testing ; Troponin/analysis
    Chemical Substances Troponin
    Language English
    Publishing date 2015-04
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 1418007-8
    ISSN 1437-4331 ; 1434-6621 ; 1437-8523
    ISSN (online) 1437-4331
    ISSN 1434-6621 ; 1437-8523
    DOI 10.1515/cclm-2014-0837
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 121: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article: Cluster analysis of COVID-19 recovery center patients at a clinic in Boston, MA 2021-2022: impact on strategies for access and personalized care.

    Tukpah, Ann-Marcia C / Patel, Jhillika / Amundson, Beret / Linares, Miguel / Sury, Meera / Sullivan, Julie / Jocelyn, Tajmah / Kissane, Brenda / Weinhouse, Gerald / Lange-Vaidya, Nancy / Lamas, Daniela / Ismail, Khalid / Pavuluri, Chandan / Cho, Michael H / Gay, Elizabeth B / Moll, Matthew

    Archives of public health = Archives belges de sante publique

    2023  Volume 81, Issue 1, Page(s) 39

    Abstract: Background: There are known disparities in COVID-19 resource utilization that may persist during the recovery period for some patients. We sought to define subpopulations of patients seeking COVID-19 recovery care in terms of symptom reporting and care ... ...

    Abstract Background: There are known disparities in COVID-19 resource utilization that may persist during the recovery period for some patients. We sought to define subpopulations of patients seeking COVID-19 recovery care in terms of symptom reporting and care utilization to better personalize their care and to identify ways to improve access to subspecialty care.
    Methods: Prospective study of adult patients with prior COVID-19 infection seen in an ambulatory COVID-19 recovery center (CRC) in Boston, Massachusetts from April 2021 to April 2022. Hierarchical clustering with complete linkage to differentiate subpopulations was done with four sociodemographic variables: sex, race, language, and insurance status. Outcomes included ICU admission, utilization of supplementary care, self-report of symptoms.
    Results: We included 1285 COVID-19 patients referred to the CRC with a mean age of 47 years, of whom 71% were female and 78% White. We identified 3 unique clusters of patients. Cluster 1 and 3 patients were more likely to have had intensive care unit (ICU) admissions; Cluster 2 were more likely to be White with commercial insurance and a low percentage of ICU admission; Cluster 3 were more likely to be Black/African American or Latino/a and have commercial insurance. Compared to Cluster 2, Cluster 1 patients were more likely to report symptoms (ORs ranging 2.4-3.75) but less likely to use support groups, psychoeducation, or care coordination (all p < 0.05). Cluster 3 patients reported greater symptoms with similar levels of community resource utilization.
    Conclusions: Within a COVID-19 recovery center, there are distinct groups of patients with different clinical and socio-demographic profiles, which translates to differential resource utilization. These insights from different subpopulations of patients can inform targeted strategies which are tailored to specific patient needs.
    Language English
    Publishing date 2023-03-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 1117688-x
    ISSN 2049-3258 ; 0778-7367 ; 0003-9578
    ISSN (online) 2049-3258
    ISSN 0778-7367 ; 0003-9578
    DOI 10.1186/s13690-023-01033-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 147: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Timing of Recognition for Perioperative Strokes Following Cardiac Surgery.

    Amundson, Beret / Hormes, Joseph / Katema, Anna / Rathakrishnan, Priyadharshi / Edwards, J Kirk / Esper, Gregory / Binongo, Jose / Lasanajak, Yi / Keeling, Brent / Halkos, Michael / Nahab, Fadi

    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association

    2020  Volume 29, Issue 12, Page(s) 105336

    Abstract: Introduction: More than half of reported perioperative strokes following cardiac surgery are identified beyond postoperative day one. The objective of our study was to determine preoperative and intraoperative factors that are associated with stroke ... ...

    Abstract Introduction: More than half of reported perioperative strokes following cardiac surgery are identified beyond postoperative day one. The objective of our study was to determine preoperative and intraoperative factors that are associated with stroke following cardiac surgery and to identify factors that may contribute delayed recognition of perioperative stroke.
    Methods: Patients undergoing coronary artery bypass surgery or isolated valve surgery from January 2, 2015 to April 28, 2017 at an academic health system were identified from the Society of Thoracic Surgeons Registry. We determined preoperative and intraoperative factors associated with perioperative stroke. Two neurologists performed retrospective chart reviews on perioperative stroke patients to determine the last seen well time and the stroke cause.
    Results: During the study period, 2795 patients underwent coronary artery bypass surgery or isolated valve surgery (mean age 64 ± 11 years, 71% male, 72% Caucasian, 9% history of stroke), of which 43 (1.5%) had a perioperative stroke; 31 (72%) patients had an embolic mechanism of stroke based on neuroimaging. In multivariable analysis, perioperative strokes were independently associated with increasing age (OR 1.04, 95% 1.01-1.07), history of stroke (OR 2.73, 95% CI 1.47-5.06), and history of thoracic aorta disease (OR 3.36, 95% CI 1.16-9.71). Strokes were identified after postoperative day one in 32 (74%) patients of which 26 (81%) had a preoperative last seen well time.
    Conclusion: Given the high frequency of preoperative last seen well time in perioperative stroke patients who are identified after postoperative day one, delayed stroke recognition may contribute to the bimodal distribution in timing of perioperative stroke. Frequent neurological monitoring within 24 hours after CABG or isolated valve surgery should be considered for all patients undergoing cardiac surgery, particularly elderly patients and those with a history of stroke or thoracic aorta disease, to improve early stroke recognition.
    MeSH term(s) Aged ; Coronary Artery Bypass/adverse effects ; Databases, Factual ; Delayed Diagnosis ; Female ; Heart Valve Prosthesis Implantation/adverse effects ; Humans ; Male ; Middle Aged ; Perioperative Period ; Retrospective Studies ; Risk Assessment ; Risk Factors ; Stroke/diagnosis ; Stroke/etiology ; Time Factors ; United States
    Language English
    Publishing date 2020-09-30
    Publishing country United States
    Document type Journal Article ; Multicenter Study
    ZDB-ID 1131675-5
    ISSN 1532-8511 ; 1052-3057
    ISSN (online) 1532-8511
    ISSN 1052-3057
    DOI 10.1016/j.jstrokecerebrovasdis.2020.105336
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3519: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Distinct cellular immune properties in cerebrospinal fluid are associated with cognition in HIV-infected individuals initiating antiretroviral therapy.

    Amundson, Beret / Lai, Lillin / Mulligan, Mark J / Xu, Yong / Zheng, Zidou / Kundu, Suprateek / Lennox, Jeffrey L / Waldrop-Valverde, Drenna / Franklin, Donald / Swaims-Kohlmeier, Alison / Letendre, Scott L / Anderson, Albert M

    Journal of neuroimmunology

    2020  Volume 344, Page(s) 577246

    Abstract: We examined the relationship between CSF immune cells and neurocognition and neuronal damage in HIV+ individuals before and after initiating antiretroviral therapy. Multivariate analysis at baseline indicated that greater CD4+ T cell abundance was ... ...

    Abstract We examined the relationship between CSF immune cells and neurocognition and neuronal damage in HIV+ individuals before and after initiating antiretroviral therapy. Multivariate analysis at baseline indicated that greater CD4+ T cell abundance was associated with better cognition (p = .017), while higher CSF HIV RNA was associated with increased neuronal damage (p = .014). Following 24 weeks of antiretroviral therapy, CD8+ T cells, HLA-DR expressing CD4+ and CD8+ T cells, B cells, NK cells, and non-classical monocyte percentage decreased in CSF. Female gender was negatively associated with cognitive performance over time, as was higher percentage of HLA-DR expressing CD8+ T cells at baseline.
    MeSH term(s) Adult ; Antiretroviral Therapy, Highly Active/methods ; Cognition/drug effects ; Cognition/physiology ; Female ; Follow-Up Studies ; HIV Infections/cerebrospinal fluid ; HIV Infections/drug therapy ; HIV Infections/immunology ; Humans ; Immunity, Cellular/drug effects ; Immunity, Cellular/immunology ; Male ; Middle Aged ; Retrospective Studies ; Viral Load/drug effects ; Viral Load/immunology
    Language English
    Publishing date 2020-04-27
    Publishing country Netherlands
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 8335-5
    ISSN 1872-8421 ; 0165-5728
    ISSN (online) 1872-8421
    ISSN 0165-5728
    DOI 10.1016/j.jneuroim.2020.577246
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1646: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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