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  1. Book ; Online ; E-Book: Health politics in Europe

    Immergut, Ellen M. / Anderson, Karen M. / Devitt, Camilla / Popic, Tamara

    a handbook

    2021  

    Author's details edited by Ellen M. Immergut, Karen M. Anderson, Camilla Devitt and Tamara Popic
    Keywords Electronic books
    Language English
    Size 1 Online-Ressource (1092 Seiten), Illustrationen
    Publisher Oxford University Press
    Publishing place Oxford
    Publishing country United States
    Document type Book ; Online ; E-Book
    Note Description based on publisher supplied metadata and other sources
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT021008916
    ISBN 978-0-19-260425-5 ; 9780198860525 ; 0-19-260425-2 ; 0198860528
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Audio / Video ; Conference proceedings ; Online: The private sector as a catalyst for health equity and a vibrant economy

    Anderson, Karen M. / Olson, Steve

    proceedings of a workshop

    2016  

    Author's details Karen M. Anderson and Steve Olson, rapporteur ; Roundtable on the Promotion of Health Equity and the Elimination of Health Disparities, Board on Population Health and Public Health Practice, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine
    Keywords Health Equity / economics ; Private Sector / economics ; Public-Private Sector Partnerships ; Socioeconomic Factors ; United States
    Language English
    Size 1 Online-Ressource (xiii, 68 pages)
    Publisher National Academies Press
    Publishing place Washington, DC
    Publishing country United States
    Document type Book ; Audio / Video ; Conference proceedings ; Online
    HBZ-ID HT019358216
    ISBN 978-0-309-44355-5 ; 0-309-44355-5
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book ; Online ; E-Book: Huntington disease

    Feigin, Andrew S. / Anderson, Karen E.

    (Handbook of clinical neurology ; volume 144)

    2017  

    Author's details volume editors Andrew S. Feigin and Karen E. Anderson
    Series title Handbook of clinical neurology ; volume 144
    Collection
    Keywords Huntington Disease ; Huntington's disease
    Subject code 616.851
    Language English
    Size 1 Online-Ressource (xvi,297 Seiten), Illustrationen
    Publisher Elsevier
    Publishing place Amsterdam
    Publishing country Netherlands
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019667454
    ISBN 978-0-12-801903-0 ; 9780128018934 ; 0-12-801903-4 ; 0128018933
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Book ; Online ; Conference proceedings: Strategies for ensuring diversity, inclusion, and meaningful participation in clinical trials

    Anderson, Karen M. / Olson, Steve

    proceedings of a workshop

    2016  

    Abstract: Even as the U.S. population becomes steadily more diverse, minorities and women remain underrepresented in clinical trials to develop new drugs and medical devices. Although progress in increasing minority participation in clinical trials has occurred, ... ...

    Institution National Academies of Sciences, Engineering, and Medicine / Roundtable on the Promotion of Health Equity and the Elimination of Health Disparities
    Author's details Karen M. Anderson and Steve Olson, rapporteurs ; Roundtable on the Promotion of Health Equity and the Elimination of Health Disparities, Board on Population Health and Public Health Practice, Health and Medicine Division ; the National Academies of Sciences, Engineering, Medicine
    Abstract Even as the U.S. population becomes steadily more diverse, minorities and women remain underrepresented in clinical trials to develop new drugs and medical devices. Although progress in increasing minority participation in clinical trials has occurred, participation rates do not fully represent the overall population of minorities in the United States. This underrepresentation threatens the health of both these populations and the general population, since greater minority representation could reveal factors that affect health in all populations. Federal legislation has sought to increase the representation of minorities and women in clinical trials, but legislation by itself has not been sufficient to overcome the many barriers to greater participation. Only much broader changes will bring about the meaningful participation of all population groups in the clinical research needed to improve health. To examine the barriers to participation in clinical trials and ways of overcoming those barriers, the National Academies of Sciences, Engineering, and Medicine held a workshop in April 2015. This publication summarizes the presentations and discussions from the workshop
    Keywords Clinical Trials as Topic ; Healthcare Disparities ; Patient Selection ; Communication Barriers ; Minority Groups ; Ethnic Groups ; Women ; United States
    Language English
    Size 1 Online-Ressource (xiii, 69 pages), Illustrationen
    Publisher National Academies Press
    Publishing place Washington, DC
    Publishing country United States
    Document type Book ; Online ; Conference proceedings
    HBZ-ID HT019158357
    ISBN 978-0-309-44357-9 ; 0-309-44357-1
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Book ; Online ; Conference proceedings: Advancing health equity for native american youth

    Anderson, Karen M. / Olson, Steve

    workshop summary

    2016  

    Institution National Academies of Sciences, Engineering, and Medicine / Roundtable on the Promotion of Health Equity and the Elimination of Health Disparities
    Author's details Karen M. Anderson and Steve Olson, Rapporteurs. Roundtable on the Promotion of Health Equity and the Elimination of Health Disparities. Board on Population Health and Public Health Practice. Health and Medicine Division. The National Academies of Sciences, Engineering, Medicine
    Language English
    Size 1 Online-Ressource (xii, 75 Seiten)
    Publisher National Academies Press
    Publishing place Washington, DC
    Publishing country United States
    Document type Book ; Online ; Conference proceedings
    HBZ-ID HT019121867
    ISBN 978-0-309-37613-6 ; 0-309-37613-0
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  6. Book ; Audio / Video ; Conference proceedings: Leveraging culture to address health inequalities

    Anderson, Karen M. / Olson, Steve

    examples from native communities ; workshop summary

    2013  

    Abstract: Leveraging Culture to Address Health Inequalities: Examples from Native Communities is the summary of a workshop convened in November 2012 by the Roundtable on the Promotion of Health Equity and the Elimination of Health Disparities of the Institute of ... ...

    Institution Institute of Medicine / Roundtable on the Promotion of Health Equity and the Elimination of Health Disparities
    Author's details Karen M. Anderson and Steve Olson, rapporteurs. Roundtable on the Promotion of Health Equity and the Elimination of Health Disparities, Board on Population Health and Public Health Practice
    Abstract "Leveraging Culture to Address Health Inequalities: Examples from Native Communities is the summary of a workshop convened in November 2012 by the Roundtable on the Promotion of Health Equity and the Elimination of Health Disparities of the Institute of Medicine. The workshop brought together more than 100 health care providers, policy makers, program administrators, researchers, and Native advocates to discuss the sizable health inequities affecting Native American, Alaska Native, First Nation, and Pacific Islander populations and the potential role of culture in helping to reduce those inequities. This report summarizes the presentations and discussion of the workshop and includes case studies that examine programs aimed at diabetes prevention and management and cancer prevention and treatment programs. In Native American tradition, the medicine wheel encompasses four different components of health: physical, emotional, mental, and spiritual. Health and well-being require balance within and among all four components. Thus, whether someone remains healthy depends as much on what happens around that person as on what happens within. Leveraging Culture to Address Health Inequalities addresses the broad role of culture in contributing to and ameliorating health inequities"--Authors
    Keywords Minority Health ; American Native Continental Ancestry Group ; Oceanic Ancestry Group ; Healthcare Disparities ; Primary Prevention ; Cultural Competency ; United States
    Language English
    Size XIII, 91 S. : graph. Darst., Kt., 24 cm
    Publisher National Acad. Press
    Publishing place Washington, DC
    Publishing country United States
    Document type Book ; Audio / Video ; Conference proceedings
    Note Includes bibliographical references
    HBZ-ID HT018344499
    ISBN 978-0-309-29256-6 ; 0-309-29256-5
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2014 A 3542 available for loan (reading room) Lesesaal EG

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  7. Article: Immunogenicity of CRISPR therapeutics-Critical considerations for clinical translation.

    Ewaisha, Radwa / Anderson, Karen S

    Frontiers in bioengineering and biotechnology

    2023  Volume 11, Page(s) 1138596

    Abstract: CRISPR offers new hope for many patients and promises to transform the way we think of future therapies. Ensuring safety of CRISPR therapeutics is a top priority for clinical translation and specific recommendations have been recently released by the FDA. ...

    Abstract CRISPR offers new hope for many patients and promises to transform the way we think of future therapies. Ensuring safety of CRISPR therapeutics is a top priority for clinical translation and specific recommendations have been recently released by the FDA. Rapid progress in the preclinical and clinical development of CRISPR therapeutics leverages years of experience with gene therapy successes and failures. Adverse events due to immunogenicity have been a major setback that has impacted the field of gene therapy. As several
    Language English
    Publishing date 2023-02-16
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2719493-0
    ISSN 2296-4185
    ISSN 2296-4185
    DOI 10.3389/fbioe.2023.1138596
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Effects of acute and chronic nicotine administration on probability discounting.

    Nolder, Katya A / Anderson, Karen G

    Behavioural pharmacology

    2023  Volume 34, Issue 8, Page(s) 468–476

    Abstract: Nicotine use is a continuing public health concern. Smokers are more likely to make risky or maladaptive decisions compared to nonsmokers, so the relation between nicotine and risky choice warrants further investigation. Risky choice can be operationally ...

    Abstract Nicotine use is a continuing public health concern. Smokers are more likely to make risky or maladaptive decisions compared to nonsmokers, so the relation between nicotine and risky choice warrants further investigation. Risky choice can be operationally defined as the choice for a larger, uncertain reinforcer over a smaller, certain reinforcer and can be assessed through a probability-discounting procedure. Acute nicotine administration has been shown to alter risky choice, but because the everyday smoker uses nicotine repeatedly, more research on chronic administration is needed and would allow for assessment of tolerance or sensitization of any effects. The present study examined effects of acute and repeated nicotine administration on probability discounting. Sprague-Dawley rats were used as subjects and the probability-discounting task involved discrete-trial choices between a small, certain reinforcer and a larger, uncertain reinforcer. The probability of larger-reinforcer delivery decreased across blocks within each session. Acute nicotine (0.1-1.0 mg/kg) administration dose-dependently increased risky choice, increased lose-stay ratios (a measure of response perseveration), and decreased reinforcement frequency. Tolerance to nicotine's effects on larger-reinforcer choice was observed after repeated 1.0 mg/kg nicotine administration. The results of the present study add to the existing literature that acute nicotine administration increases risky choice and demonstrates that tolerance to this effect develops after chronic exposure to the drug. Possible behavioral mechanisms behind this effect are discussed, as are suggestions for future research on nicotine and risky choice.
    MeSH term(s) Animals ; Rats ; Choice Behavior ; Conditioning, Operant ; Delay Discounting ; Impulsive Behavior ; Nicotine/pharmacology ; Probability ; Rats, Sprague-Dawley
    Chemical Substances Nicotine (6M3C89ZY6R)
    Language English
    Publishing date 2023-03-23
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1027374-8
    ISSN 1473-5849 ; 0955-8810
    ISSN (online) 1473-5849
    ISSN 0955-8810
    DOI 10.1097/FBP.0000000000000753
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2883: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Book: Behavioral neurology of movement disorders

    Anderson, Karen E.

    (Advances in neurology ; 96)

    2005  

    Author's details ed. Karen E. Anderson
    Series title Advances in neurology ; 96
    Collection
    Keywords Bewegungsstörung ; Neurologie
    Subject Klinische Neurologie ; Motorische Störung ; Bewegungsschwäche
    Language English
    Size XXI, 378 S. : Ill., graph. Darst.
    Edition 2. ed.
    Publisher Lippincott Williams & Wilkins
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT014221930
    ISBN 0-7817-5169-1 ; 978-0-7817-5169-8
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Se 198 -96- verfügbar in Königswinter Königswinter

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  10. Article ; Online: Therapeutic Targeting of FGFR Signaling in Head and Neck Cancer.

    Wang, Zechen / Anderson, Karen S

    Cancer journal (Sudbury, Mass.)

    2022  Volume 28, Issue 5, Page(s) 354–362

    Abstract: Abstract: Squamous cell carcinoma of the head and neck (HNSCC) is the sixth most prevalent cancer worldwide, with an annual incidence of 600,000 new cases. Despite advances in surgery, chemotherapy, and radiotherapy, the overall survival for HNSCC ... ...

    Abstract Abstract: Squamous cell carcinoma of the head and neck (HNSCC) is the sixth most prevalent cancer worldwide, with an annual incidence of 600,000 new cases. Despite advances in surgery, chemotherapy, and radiotherapy, the overall survival for HNSCC patients has not been significantly improved over the past several decades. Fibroblast growth factor (FGF)/fibroblast growth factor receptor (FGFR) genomic alterations are frequently detected in HNSCC, including amplification, activating mutation, and chromosomal rearrangement. Among them, FGFR1 amplification, FGF amplifications, and FGFR3 mutations are the most prevalent. In addition, FGF/FGFR expression has also been observed in most HNSCCs. However, the prognostic value of FGF/FGFR aberrations remains unclear, especially for gene amplification and overexpression. Nonetheless, FGF/FGFR has been a promising target for HNSCC treatment, and recent preclinical studies demonstrate the potential of the combination treatment regimens involving FGFR inhibitors on HNSCC. Therefore, there are a number of FGFR inhibitors currently in clinical trials for the treatment of head and neck cancers.
    MeSH term(s) Carcinoma, Squamous Cell ; Fibroblast Growth Factors/genetics ; Fibroblast Growth Factors/metabolism ; Fibroblast Growth Factors/therapeutic use ; Head and Neck Neoplasms/drug therapy ; Head and Neck Neoplasms/genetics ; Humans ; Signal Transduction ; Squamous Cell Carcinoma of Head and Neck/genetics ; Squamous Cell Carcinoma of Head and Neck/therapy
    Chemical Substances Fibroblast Growth Factors (62031-54-3)
    Language English
    Publishing date 2022-10-12
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2018400-1
    ISSN 1540-336X ; 1528-9117 ; 1081-4442
    ISSN (online) 1540-336X
    ISSN 1528-9117 ; 1081-4442
    DOI 10.1097/PPO.0000000000000615
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4470: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 163: Show issues

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