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Book ; Thesis: Crosstalk between inflammation and coagulation in acute pancreatitis

Andersson, Ellen

experimental and clinical studies

(Doctoral dissertation series ; 2010,79 ; Bulletin from the Department of Surgery, University of Lund ; 138)

2010

Author's details	av Ellen Andersson
Series title	Doctoral dissertation series ; 2010,79 Bulletin from the Department of Surgery, University of Lund ; 138
Collection
Language	English
Size	getr. Zählung : Ill., graph. Darst.
Publishing country	Sweden
Document type	Book ; Thesis
Thesis / German Habilitation thesis	Lund, Univ., Diss., 2010
Note	Zsfassung in schwed. Sprache ; Enth. 5 Sonderabdr.
HBZ-ID	HT016867509
ISBN	978-91-86443-95-5 ; 91-86443-95-X
Database	Catalogue ZB MED Medicine, Health

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Article ; Online: Author's Reply: Pulmonary Recruitment Maneuver Reduces Shoulder Pain and Nausea After Laparoscopic Cholecystectomy: A Randomized Controlled Trial.

Pasquier, Ebba Kihlstedt / Andersson, Ellen

World journal of surgery

2022 Volume 46, Issue 5, Page(s) 1244

MeSH term(s)	Cholecystectomy, Laparoscopic/adverse effects ; Humans ; Nausea ; Pain, Postoperative/etiology ; Pain, Postoperative/prevention & control ; Pneumoperitoneum, Artificial ; Shoulder Pain/etiology ; Shoulder Pain/prevention & control
Language	English
Publishing date	2022-02-20
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	224043-9
ISSN	1432-2323 ; 0364-2313
ISSN (online)	1432-2323
ISSN	0364-2313
DOI	10.1007/s00268-022-06478-0
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Zs.A 1336: Show issues

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Article ; Online: Using the 5-Item Medication Adherence Report Scale (MARS-5) to Screen for Non-adherence to Vitamin and Mineral Supplementation After Bariatric Surgery.

Spetz, Kristina / Olbers, Torsten / Östbring, Malin / Moon, Zoe / Horne, Rob / Andersson, Ellen

Obesity surgery

2024 Volume 34, Issue 2, Page(s) 576–582

Abstract: Introduction: Poor adherence to recommended vitamin and mineral supplementation after bariatric surgery is common and challenging for healthcare professionals to identify. There are several questionnaires for self-reporting of adherence to chronic ... ...

Abstract	Introduction: Poor adherence to recommended vitamin and mineral supplementation after bariatric surgery is common and challenging for healthcare professionals to identify. There are several questionnaires for self-reporting of adherence to chronic medication, but none has so far been evaluated for assessment of adherence to vitamin and mineral supplementation after bariatric surgery. The aim of this study was to assess the accuracy of the 5-item Medication Adherence Report Scale (MARS-5) in measuring adherence to vitamin and mineral supplementation post bariatric surgery (gastric bypass or sleeve gastrectomy). Method: The psychometric properties of MARS-5 for vitamin and mineral supplementation were validated in two cohorts: one at 1 year post bariatric surgery (n = 120) and the other at 2 years post-surgery (n = 211). MARS-5 was compared to pharmacy refill data for vitamin B Results: Correlation analyses demonstrated that the MARS-5 had acceptable validity compared to objectively measured adherence rates from pharmacy refill data (calculated as continuous, multiple-interval measures of medication availability/gaps-coefficient ranged from 0.49 to 0.54). Internal reliability (Cronbach's α) was high: 0.81 and 0.95, respectively. There was a clear ceiling effect where one out of three had a maximum score on MARS-5. Conclusion: MARS-5 demonstrated acceptable psychometric properties for assessment of adherence to vitamin and mineral supplementation post bariatric surgery.
MeSH term(s)	Humans ; Vitamins/therapeutic use ; Reproducibility of Results ; Obesity, Morbid/surgery ; Bariatric Surgery ; Gastric Bypass ; Dietary Supplements ; Minerals ; Medication Adherence
Chemical Substances	Vitamins ; Minerals
Language	English
Publishing date	2024-01-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	1070827-3
ISSN	1708-0428 ; 0960-8923
ISSN (online)	1708-0428
ISSN	0960-8923
DOI	10.1007/s11695-023-07027-x
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Article ; Online: Obstruction after Sleeve Gastrectomy, Prevalence, and Interventions: a Cohort Study of 9,726 Patients with Data from the Scandinavian Obesity Surgery Registry (SOReg).

Sillén, Linda / Andersson, Ellen / Olbers, Torsten / Edholm, David

Obesity surgery

2021 Volume 31, Issue 11, Page(s) 4701–4707

Abstract: Background: Sleeve gastrectomy (SG) is the most common bariatric procedure worldwide. Obstructive symptoms, together with leaks, are among the most serious postoperative complications. This study aimed to investigate the incidence of symptomatic ... ...

Abstract	Background: Sleeve gastrectomy (SG) is the most common bariatric procedure worldwide. Obstructive symptoms, together with leaks, are among the most serious postoperative complications. This study aimed to investigate the incidence of symptomatic obstruction after SG in Sweden and to explore risk factors, treatment strategies, and outcome. Methods: A retrospective analysis of prospectively collected data from the Scandinavian Obesity Surgery Registry (SOReg) of patients undergoing SG and developed obstruction symptoms within the first postoperative year was performed. For patients who had undergone any re-intervention, such as endoscopic dilatation or remedial surgery, medical charts were reviewed. Results: From 2007 to 2018, a total of 9,726 SG were performed, and 59 (0.6%) of them developed postoperative obstruction. Intolerance of solid food was the most common symptom associated with obstruction (80%). Sixty-one percent of the patients had obstruction at the level of incisura angularis. Longer operative time, higher rate of perioperative complications, longer hospital stay, and oversewing the staple line were associated with an increased risk of obstruction. Endoscopic balloon dilatation was performed in 59% of patients (n=35) and successful in 18 patients (51%). Twenty-one patients (36%) underwent surgical conversion to Roux-en-Y gastric bypass (RYGB). After revisional surgery, 11 (52%) reported complete relief of symptoms. Conclusions: Obstruction was rare (0.6%) and most often located at the incisura angularis. Obstruction was associated with longer operative time, perioperative complications, oversewing of the staple line, and longer hospital stay. Endoscopic dilatation or surgical conversion to RYGB frequently alleviates symptoms, but despite treatment, almost 50% reported residual symptoms.
MeSH term(s)	Cohort Studies ; Gastrectomy/adverse effects ; Gastric Bypass ; Humans ; Obesity, Morbid/surgery ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Postoperative Complications/surgery ; Prevalence ; Registries ; Retrospective Studies ; Treatment Outcome
Language	English
Publishing date	2021-08-15
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1070827-3
ISSN	1708-0428 ; 0960-8923
ISSN (online)	1708-0428
ISSN	0960-8923
DOI	10.1007/s11695-021-05574-9
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Article ; Online: Women's lived experiences of sex hormones and life-related to bariatric surgery: an interpretative qualitative study.

Paul, Rebecca / Andersson, Ellen / Olbers, Torsten / Frisk, Jessica / Berterö, Carina M

BMJ open

2023 Volume 13, Issue 6, Page(s) e072085

Abstract: Objectives: The study aimed to explore the lived experiences of women with severe obesity before and after undergoing bariatric surgery with a special focus on possible effects of changed sex hormone levels.: Design: A qualitative interview study ... ...

Abstract	Objectives: The study aimed to explore the lived experiences of women with severe obesity before and after undergoing bariatric surgery with a special focus on possible effects of changed sex hormone levels. Design: A qualitative interview study with transcribed text analysis based on Gadamer's hermeneutics. Setting: Regional hospital and outpatient bariatric clinic in central Sweden. Participants: Ten women (age 23-38 years) having undergone Roux-en-Y gastric bypass surgery between 2016 and 2019 were interviewed. Results: The transcribed interviews were analysed according to Gadamer's hermeneutics. Text horizons, interpreter horizons and fact horizons were derived and formed the fusions 'Recognition of unhealthy body weight', 'Dealing with other people's opinions and society's norms', 'Life has changed in a positive way' and 'Accepting inner self and bodily changes'. Conclusion: Women highlighted weight and body size in their responses. The study provided a deeper understanding of the situation of women living with obesity and pros and cons of having undergone bariatric surgery. Experiences of changes in sex hormones and fertility were discussed but not central to the informants. Participants emphasised the need to be prepared and properly supported in dealing with changes in life after bariatric surgery and subsequent weight loss.
MeSH term(s)	Humans ; Female ; Young Adult ; Adult ; Bariatric Surgery ; Obesity, Morbid/surgery ; Obesity/surgery ; Gastric Bypass ; Gonadal Steroid Hormones ; Qualitative Research
Chemical Substances	Gonadal Steroid Hormones
Language	English
Publishing date	2023-06-23
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2599832-8
ISSN	2044-6055 ; 2044-6055
ISSN (online)	2044-6055
ISSN	2044-6055
DOI	10.1136/bmjopen-2023-072085
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Article ; Online: Motherhood and motivations for bariatric surgery - a qualitative study.

Paul, Rebecca / Drott, Jenny / Olbers, Torsten / Frisk, Jessica / Andersson, Ellen

Human fertility (Cambridge, England)

2022 Volume 26, Issue 2, Page(s) 257–265

Abstract: Obesity and its concomitant comorbidities have a myriad of detrimental effects on health, fertility, and quality of life. Bariatric surgery is an effective treatment for inducing weight loss and reduction of obesity-related comorbidities including ... ...

Abstract	Obesity and its concomitant comorbidities have a myriad of detrimental effects on health, fertility, and quality of life. Bariatric surgery is an effective treatment for inducing weight loss and reduction of obesity-related comorbidities including subfertility. The aim of this study was to explore the expectations and experiences of women with a desire to have children as a motivation for undergoing bariatric surgery. An inductive qualitative design was used. Fourteen women were interviewed, and transcriptions were analysed with thematic analysis. Two themes emerged: (i) Motherhood and Femininity and (ii) A Normal Life. Participants found no other solution than to seek bariatric surgery to be able to become pregnant and carry a child to term. Coping physically with pregnancy and being an active mother were important factors. Overall, postoperative expectations were met, and the women experienced the effects of normalised sex hormone levels, were more physically mobile, and were released from the previous social hindrances that obesity caused them. This study has clinical implications for providing support and information to women with subfertility considering bariatric surgery and to better understand their experiences of life after bariatric surgery.
MeSH term(s)	Pregnancy ; Child ; Humans ; Female ; Motivation ; Quality of Life ; Obesity/surgery ; Bariatric Surgery ; Comorbidity ; Qualitative Research
Language	English
Publishing date	2022-03-04
Publishing country	England
Document type	Journal Article
ZDB-ID	2086960-5
ISSN	1742-8149 ; 1464-7273
ISSN (online)	1742-8149
ISSN	1464-7273
DOI	10.1080/14647273.2022.2045520
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Zs.A 5775: Show issues

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Article ; Online: Very low risk of short bowel after Roux-en-Y gastric bypass - a large nationwide Swedish cohort study.

Edholm, David / Hofgård, Johan Olsson / Andersson, Ellen / Stenberg, Erik / Olbers, Torsten

Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery

2023 Volume 20, Issue 4, Page(s) 362–366

Abstract: Background: Roux-en-Y gastric bypass (RYGB) is one of the most common bariatric procedures. Internal herniation may lead to small bowel ischemia requiring small bowel resection, resulting in short bowel syndrome.: Objective: To determine the ... ...

Abstract	Background: Roux-en-Y gastric bypass (RYGB) is one of the most common bariatric procedures. Internal herniation may lead to small bowel ischemia requiring small bowel resection, resulting in short bowel syndrome. Objective: To determine the incidence of extensive small bowel resection in patients operated with RYGB. We also aimed to look for early clinical warning signs among patients requiring extensive small bowel resection. Setting: Cohort from national quality registers. Methods: All patients having undergone RYGB between January 2007 to June 2019 were analyzed in the Scandinavian Obesity Surgery Registry (SOReg). We identified patients with small bowel obstruction (SBO) for whom small bowel resection was necessary. Additionally, we assessed clinical signs in these patients. Results: The study included 57,255 patients having undergone RYGB. Closure of the mesenteric openings was performed in 78%. Surgery for SBO was required in 3659 (6%) of patients, and small bowel resection in 188 (.3%). Extensive small bowel resection, resulting in less than 1.5 meters of remaining small bowel, was required in 7 patients (.01%). All patients with extensive small bowel resection presented with abdominal pain and had confirmed internal herniation as the cause of the small bowel resection, and 2 of 7 patients died. Closure of mesenteric defects was not associated with a reduction in overall small bowel resection rates (P = .89) CONCLUSION: Surgery for SBO after RYGB was common (6%). The risk of extensive small bowel resection leading to short bowel was low (.01%). Patients with abdominal pain after RYGB should be assessed for internal hernia, as it can be devastating.
MeSH term(s)	Humans ; Gastric Bypass/adverse effects ; Gastric Bypass/methods ; Cohort Studies ; Sweden/epidemiology ; Retrospective Studies ; Laparoscopy/methods ; Hernia, Abdominal/epidemiology ; Hernia, Abdominal/etiology ; Hernia, Abdominal/surgery ; Intestinal Obstruction/epidemiology ; Intestinal Obstruction/etiology ; Intestinal Obstruction/surgery ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Postoperative Complications/surgery ; Abdominal Pain/epidemiology ; Abdominal Pain/etiology ; Obesity, Morbid/complications
Language	English
Publishing date	2023-11-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	2274243-8
ISSN	1878-7533 ; 1550-7289
ISSN (online)	1878-7533
ISSN	1550-7289
DOI	10.1016/j.soard.2023.10.014
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Article: Adherence to vitamin and mineral supplementation after bariatric surgery - A two-year cohort study.

Spetz, Kristina / Svedjeholm, Sanna / Roos, Susanne / Grehn, Susanne / Olbers, Torsten / Andersson, Ellen

Obesity research & clinical practice

2022 Volume 16, Issue 5, Page(s) 407–412

Abstract: Background: Lifelong vitamin and mineral supplementation is recommended after bariatric surgery to prevent nutritional deficiencies, but it is not clear to which extent patients adhere to the recommended medication. The aim of this study was to assess ... ...

Abstract	Background: Lifelong vitamin and mineral supplementation is recommended after bariatric surgery to prevent nutritional deficiencies, but it is not clear to which extent patients adhere to the recommended medication. The aim of this study was to assess adherence to supplementation. Additionally, we assessed predictors of low adherence and biochemical deficiencies. Methods: 263 adults were followed two years post bariatric surgery (89.4 % Roux-en-Y gastric bypass, 10.6 % sleeve gastrectomy) regarding adherence to calcium-vitamin D, vitamin B Results: About 60 % of the study participants had high adherence-rate (≥ 80 %) two years post-surgery, but a significant proportion had discontinued the intended lifelong supplementation: 15 % for calcium-vitamin D and 12 % for B Conclusion: Substantial variation existed in adherence to supplementation regimens after bariatric surgery during the first two years after bariatric surgery, but biochemical deficiencies were rare. The results indicate need for tailored follow-up and strategies to support long-term persistence.
MeSH term(s)	Adult ; Humans ; Obesity, Morbid/surgery ; Vitamins/therapeutic use ; Cohort Studies ; Calcium ; Gastric Bypass/adverse effects ; Bariatric Surgery/adverse effects ; Gastrectomy/adverse effects ; Vitamin D ; Dietary Supplements ; Minerals ; Iron
Chemical Substances	Vitamins ; Calcium (SY7Q814VUP) ; Vitamin D (1406-16-2) ; Minerals ; Iron (E1UOL152H7)
Language	English
Publishing date	2022-09-20
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2274031-4
ISSN	1878-0318 ; 1871-403X
ISSN (online)	1878-0318
ISSN	1871-403X
DOI	10.1016/j.orcp.2022.09.001
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Article ; Online: Outcomes of bariatric surgery for patients with prevalent inflammatory bowel disease: A nationwide registry-based cohort study.

Wallhuss, Andreas / Ottosson, Johan / Cao, Yang / Andersson, Ellen / Bergemalm, Daniel / Eriksson, Carl / Olén, Ola / Szabo, Eva / Stenberg, Erik

Surgery

2023 Volume 174, Issue 2, Page(s) 144–151

Abstract: Background: Obesity is becoming more prevalent in patients with inflammatory bowel disease. Although bariatric surgery is an effective treatment for obesity, questions remain regarding its safety and effectiveness for patients with inflammatory bowel ... ...

Abstract	Background: Obesity is becoming more prevalent in patients with inflammatory bowel disease. Although bariatric surgery is an effective treatment for obesity, questions remain regarding its safety and effectiveness for patients with inflammatory bowel disease. The aim of this study was to evaluate the safety and effectiveness of bariatric surgery in patients with inflammatory bowel disease. Method: This registry-based, propensity-matched cohort study included all patients who had primary Roux-en-Y gastric bypass or sleeve gastrectomy in Sweden from January 2007 to June 2020 who had an inflammatory bowel disease diagnosis and matched control patients without an inflammatory bowel disease diagnosis. The study included data from the Scandinavian Obesity Surgery Registry, the National Patient Register, the Swedish Prescribed Drugs Register, the Total Population Register, and the Education Register from Statistics Sweden. Results: In total, 71,093 patients who underwent bariatric surgery, including 194 with Crohn's disease and 306 with ulcerative colitis, were 1:5 matched to non-inflammatory bowel disease control patients. The patients with Crohn's disease had a higher readmission rate within 30 days (10.7% vs 6.1%, odds ratio = 1.84, 95% confidence interval 1.02-3.31) than the control patients, with no significant difference between the surgical methods. The patients with ulcerative colitis had a higher risk for serious postoperative complications after Roux-en-Y gastric bypass (8.0% vs 3.7%, odds ratio = 2.64, 95% confidence interval 1.15-6.05) but not after sleeve gastrectomy compared to control patients (0.8% vs 2.3%). No difference was observed in postoperative weight loss or postoperative health-related quality of life. Conclusion: Sleeve gastrectomy appears to be a safe and effective treatment for obesity in patients with inflammatory bowel disease, whereas Roux-en-Y gastric bypass was associated with a higher risk for postoperative complications in patients with ulcerative colitis.
MeSH term(s)	Humans ; Obesity, Morbid/surgery ; Cohort Studies ; Crohn Disease/surgery ; Colitis, Ulcerative/complications ; Colitis, Ulcerative/surgery ; Quality of Life ; Bariatric Surgery/adverse effects ; Bariatric Surgery/methods ; Gastric Bypass/adverse effects ; Gastric Bypass/methods ; Obesity/complications ; Obesity/epidemiology ; Obesity/surgery ; Inflammatory Bowel Diseases/complications ; Inflammatory Bowel Diseases/epidemiology ; Inflammatory Bowel Diseases/surgery ; Treatment Outcome ; Gastrectomy/adverse effects ; Gastrectomy/methods ; Registries ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Postoperative Complications/surgery ; Retrospective Studies
Language	English
Publishing date	2023-05-30
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	202467-6
ISSN	1532-7361 ; 0039-6060
ISSN (online)	1532-7361
ISSN	0039-6060
DOI	10.1016/j.surg.2023.04.059
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Article ; Online: Effect of a Smartphone Application on Physical Activity and Weight Loss After Bariatric Surgery-Results from a Randomized Controlled Trial.

Bonn, Stephanie E / Hult, Mari / Spetz, Kristina / Eke, Helén / Andersson, Ellen / Wirén, Mikael / Löf, Marie / Trolle Lagerros, Ylva

Obesity surgery

2023 Volume 33, Issue 9, Page(s) 2841–2850

Abstract: Purpose: Ways to motivate and support patients in being physically active after bariatric surgery are needed. This trial was aimed at evaluating the effect of using a smartphone application targeting physical activity during 12 weeks on moderate-to- ... ...

Abstract	Purpose: Ways to motivate and support patients in being physically active after bariatric surgery are needed. This trial was aimed at evaluating the effect of using a smartphone application targeting physical activity during 12 weeks on moderate-to-vigorous physical activity (MVPA, primary outcome) and secondary outcomes of inactivity, light physical activity (LPA), body mass index (BMI), and percent total weight loss (%TWL) after bariatric surgery. Materials and methods: Data from a randomized controlled trial comprising 146 patients (79.5% women) undergoing bariatric surgery was analyzed. Mean age and BMI pre-surgery were 40.9 years and 40.5 kg/m Results: A significant effect of the intervention (group-by-time interaction 16.2, 95% CI 3.5 to 28.9) was seen for MVPA at 18 weeks; the intervention group had increased their MVPA since baseline, while the control group had decreased their MVPA. The control group had lowered their BMI approximately 1 kg/m Conclusion: Our results indicate that use of a smartphone application targeting physical activity may have the potential to promote short-term MVPA post bariatric surgery. Trial registration: Clinicaltrials.gov : NCT03480464.
MeSH term(s)	Humans ; Female ; Male ; Obesity, Morbid/surgery ; Smartphone ; Exercise ; Bariatric Surgery ; Weight Loss
Language	English
Publishing date	2023-07-27
Publishing country	United States
Document type	Randomized Controlled Trial ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1070827-3
ISSN	1708-0428 ; 0960-8923
ISSN (online)	1708-0428
ISSN	0960-8923
DOI	10.1007/s11695-023-06753-6
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