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  1. Article ; Online: The Effect of Various Boiling Conditions on Reduction of Phosphorus and Protein in Meat.

    Ando, Sakiko / Sakuma, Masae / Morimoto, Yuuka / Arai, Hidekazu

    Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation

    2015  Volume 25, Issue 6, Page(s) 504–509

    Abstract: Objective: Dietary phosphorus restriction and intake adequate amount of protein play a prominent role in control of hyperphosphatemia and prevention of protein-energy malnutrition for chronic kidney disease (CKD) and dialysis patients. To reduce dietary ...

    Abstract Objective: Dietary phosphorus restriction and intake adequate amount of protein play a prominent role in control of hyperphosphatemia and prevention of protein-energy malnutrition for chronic kidney disease (CKD) and dialysis patients. To reduce dietary phosphorus intake, we focused on boiling, which can affect the bioavailability of nutrients by changing mineral solubility and breaking down food structure. The aim of this study was to assess the effect of boiling on the phosphorus and protein content of beef. We boiled beef in differing fluid mediums, varied the size of the meat, method of boiling and cooking time, and compared the effects on phosphorus reduction.
    Design and methods: We evaluated the retention values of phosphorus, protein, and phosphorus to protein ratio in beef before and after boiling. We used differing fluid mediums (soft water, hard water, 5% solution of acetate, and 0.5% sodium bicarbonate water), varied the size of the meat (block, sliced, and cubed), different boiling methods (normal pan and pressure cooker [PC]), and different cooking time (10 and 30 minutes).
    Results: The soft water sample had lower phosphorus to protein ratio compared with the hard water, 5% solution of acetate, and 0.5% sodium bicarbonate water sample. The phosphorus content of the sliced meat sample at 30 minutes was almost half the content of the uncut block of sample at 10 minutes. The block PC sample for 10 minutes had a phosphorus content almost equal to the block normal pan sample for 30 minutes. Moreover, the sliced PC sample at 30 minutes had the lowest phosphorus to protein ratio of all the samples.
    Conclusions: Our results show that boiling with soft water, sliced food and a PC is the preferable cooking procedure for chronic kidney disease and dialysis patients because it allows for a reduction of the phosphorus content while preserving protein content, and it would bring the suppression of protein-energy malnutrition.
    MeSH term(s) Animals ; Cooking/methods ; Dietary Proteins/analysis ; Humans ; Hyperphosphatemia/etiology ; Hyperphosphatemia/prevention & control ; Meat/analysis ; Phosphorus, Dietary/analysis ; Protein-Energy Malnutrition/etiology ; Protein-Energy Malnutrition/prevention & control ; Renal Insufficiency, Chronic/complications ; Renal Insufficiency, Chronic/diet therapy
    Chemical Substances Dietary Proteins ; Phosphorus, Dietary
    Language English
    Publishing date 2015-11
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1080003-7
    ISSN 1532-8503 ; 1051-2276
    ISSN (online) 1532-8503
    ISSN 1051-2276
    DOI 10.1053/j.jrn.2015.05.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Availability of 24-h urine collection method on dietary phosphorus intake estimation.

    Sakuma, Masae / Morimoto, Yuuka / Suzuki, Yukie / Suzuki, Akitsu / Noda, Saaya / Nishino, Kanaho / Ando, Sakiko / Ishikawa, Makoto / Arai, Hidekazu

    Journal of clinical biochemistry and nutrition

    2016  Volume 60, Issue 2, Page(s) 125–129

    Abstract: Accurate assessment of dietary phosphorus intake is necessary to prevent hyperphosphatemia. The aim of this study was to evaluate the 24-h urine collection method for estimation of phosphate intake in healthy males. Two experiments, a 1-day and a 5-day ... ...

    Abstract Accurate assessment of dietary phosphorus intake is necessary to prevent hyperphosphatemia. The aim of this study was to evaluate the 24-h urine collection method for estimation of phosphate intake in healthy males. Two experiments, a 1-day and a 5-day loading test, were performed. After an overnight fast, subjects consumed test meals, 24-h urine collection was performed, and blood samples were obtained. In the 5-day loading test, a phosphorus supplement was orally administered on day 3. The association between the phosphorus content of test meals and urinary excretion, anthropometric indices, and blood biomarkers was analyzed to develop a more precise formula for estimating phosphorus intake. In the 1-day loading test, the standard deviation of predictive phosphorus intake, based on multiple linear regression analysis, was less than that for the phosphorus absorption rate. In the 5-day loading test, urinary phosphorus excretion was similar on days 2, 4 and 5, but was significantly higher on day 3 after phosphorus supplementation. Our results indicate that estimation of dietary phosphorus intake with the 24-h urine collection method, using the amount of phosphorus and urea nitrogen excretion, may increase the precision of short-term monitoring.
    Language English
    Publishing date 2016-12-06
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 632945-7
    ISSN 1880-5086 ; 0912-0009
    ISSN (online) 1880-5086
    ISSN 0912-0009
    DOI 10.3164/jcbn.16-50
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Nocturnal eating disturbs phosphorus excretion in young subjects: a randomized crossover trial.

    Sakuma, Masae / Noda, Saaya / Morimoto, Yuuka / Suzuki, Akitsu / Nishino, Kanaho / Ando, Sakiko / Umeda, Minako / Ishikawa, Makoto / Arai, Hidekazu

    Nutrition journal

    2015  Volume 14, Page(s) 106

    Abstract: Background: Nocturnal eating have recently increased. Serum phosphorus levels and regulators of phosphorus have circadian variations, so it is suggested that the timing of eating may be important in controlling serum phosphorus levels. However, there ... ...

    Abstract Background: Nocturnal eating have recently increased. Serum phosphorus levels and regulators of phosphorus have circadian variations, so it is suggested that the timing of eating may be important in controlling serum phosphorus levels. However, there have been no reports on the effects of nocturnal eating on phosphorus metabolism. The objective was to evaluate the effects of nocturnal eating on phosphorus metabolism.
    Methods: Fourteen healthy men participated in two experimental protocols with differing dinner times. The design of this study was a crossover study. The subjects were served test meals three times (breakfast; 07:30 h, lunch; 12:30 h, dinner; 17:30 or 22:30 h) a day. Blood and urine samples were collected to assess diurnal variation until the following morning.
    Results: The following morning, fasting serum phosphorus levels in the late dinner group were markedly higher than those in the early dinner group (p < 0.001), although serum calcium levels were maintained at approximately constant levels throughout the day in both groups. Fluctuations in urinary calcium excretion were synchronized with the timing of dinner eating, however, fluctuations in urinary phosphorus excretion were not synchronized. Urinary phosphorus excretions at night were inhibited in the late dinner group. In the late dinner group, intact parathyroid hormone levels didn't decrease, and they were significantly higher in this group compared with the early dinner group at 20:00 h (p = 0.004). The following morning, fasting serum fibroblast growth factor 23 levels in the late dinner group had not changed, but those in the early dinner group were significantly increased (p = 0.003). Serum free fatty acid levels before dinner were significantly higher in the late dinner group compared with the early dinner group.
    Conclusions: Our results indicate that nocturnal eating inhibits phosphorus excretion. It is suggested that nocturnal eating should be abstained from to manage serum phosphorus levels to within an adequate range.
    MeSH term(s) Adult ; Circadian Rhythm ; Cross-Over Studies ; Feeding Behavior ; Humans ; Male ; Phosphorus/blood ; Phosphorus/urine ; Young Adult
    Chemical Substances Phosphorus (27YLU75U4W)
    Language English
    Publishing date 2015-10-08
    Publishing country England
    Document type Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ISSN 1475-2891
    ISSN (online) 1475-2891
    DOI 10.1186/s12937-015-0096-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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