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Article ; Online: Twenty five years of the Spanish Journal of Prison Health

Andrés Marco

Revista Española de Sanidad Penitenciaria, Vol 25, Iss 3, Pp 87-

2024 Volume 88

Keywords	Medicine ; R ; Public aspects of medicine ; RA1-1270
Language	English
Publishing date	2024-01-01T00:00:00Z
Publisher	Sociedad Española de Sanidad Penitenciaria
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Changes in the epidemiological pattern of chronic B hepatitis amongst inmates in Catalonia: current prevalence and predictive variables.

Abdo Sanmartino, Indiana Jesús / Guerrero-Moreno, Rafael A / Mouriño, Andrés Marco

Revista espanola de sanidad penitenciaria

2024 Volume 25, Issue 3, Page(s) 89–97

Abstract: Background: The epidemiology of chronic hepatitis B (CHB) in Spain has changed due to migratory movements and the implementation of vaccination programs. The objective is to determine if prevalence has also changed amongst in Catalonia and the potential ...

Abstract	Background: The epidemiology of chronic hepatitis B (CHB) in Spain has changed due to migratory movements and the implementation of vaccination programs. The objective is to determine if prevalence has also changed amongst in Catalonia and the potential predictive variables of the infection. Material and method: Observational cross-sectional multi-centre study of CHB prevalence. Epidemiological and clinical variables were included, and their predictive capacity is analysed by means of a multivariable logistic regression model. Results: A total of 6508 prisoners were studied. CHB prevalence was 1.7%, much less than in studies carried out in previous years. In inmates from North Africa, Asia, Eastern Europe, and Sub-Saharan Africa the CHB rate was 2.8, 4.2, 4.9 and 16.2 times higher, respectively, than amongst those born in Spain, which was 0.6%, the same as in the general population. CHB was associated with: a) being an immigrant [2.6%; OR: 4.18 (CI: 2.50-6.90; P <0.001); b) being unvaccinated (3.1%; OR: 0.13; CI: 0.06-0.26; P <0.001); and c) being infected by the human immunodeficiency virus (HIV) [3.9%; OR: 3.23; CI: 1.24-8.40; P = 0.016]. Conclusion: Vaccination against HBV (hepatitis B virus) has greatly reduced CHB prevalence in inmates over the past 30 years but remains high in immigrants and those with HIV. We recommend: a) maintaining HBV screening amongst inmates; b) continuing with vaccination programmes; and c) referring CHB cases to specialized programs for further study and treatment if needed.
MeSH term(s)	Humans ; Cross-Sectional Studies ; Hepatitis, Chronic ; HIV ; HIV Infections/epidemiology ; Prevalence ; Prisoners ; Spain/epidemiology
Language	English
Publishing date	2024-01-29
Publishing country	Spain
Document type	Journal Article ; Multicenter Study ; Observational Study
ZDB-ID	2424262-7
ISSN	2013-6463 ; 2013-6463
ISSN (online)	2013-6463
ISSN	2013-6463
DOI	10.18176/resp.00074
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Changes in the epidemiological pattern of chronic B hepatitis amongst inmates in Catalonia

Indiana Jesús Abdo Sanmartino / Rafael A Guerrero-Moreno / Andrés Marco Mouriño

Revista Española de Sanidad Penitenciaria, Vol 25, Iss 3, Pp 89-

current prevalence and predictive variables

2024 Volume 97

Abstract: Abstract Background: The epidemiology of chronic hepatitis B (CHB) in Spain has changed due to migratory movements and the implementation of vaccination programs. The objective is to determine if prevalence has also changed amongst in Catalonia and the ... ...

Abstract	Abstract Background: The epidemiology of chronic hepatitis B (CHB) in Spain has changed due to migratory movements and the implementation of vaccination programs. The objective is to determine if prevalence has also changed amongst in Catalonia and the potential predictive variables of the infection. Material and method: Observational cross-sectional multi-centre study of CHB prevalence. Epidemiological and clinical variables were included, and their predictive capacity is analysed by means of a multivariable logistic regression model. Results: A total of 6508 prisoners were studied. CHB prevalence was 1.7%, much less than in studies carried out in previous years. In inmates from North Africa, Asia, Eastern Europe, and Sub-Saharan Africa the CHB rate was 2.8, 4.2, 4.9 and 16.2 times higher, respectively, than amongst those born in Spain, which was 0.6%, the same as in the general population. CHB was associated with: a) being an immigrant [2.6%; OR: 4.18 (CI: 2.50-6.90; P <0.001); b) being unvaccinated (3.1%; OR: 0.13; CI: 0.06-0.26; P <0.001); and c) being infected by the human immunodeficiency virus (HIV) [3.9%; OR: 3.23; CI: 1.24-8.40; P = 0.016]. Conclusion: Vaccination against HBV (hepatitis B virus) has greatly reduced CHB prevalence in inmates over the past 30 years but remains high in immigrants and those with HIV. We recommend: a) maintaining HBV screening amongst inmates; b) continuing with vaccination programmes; and c) referring CHB cases to specialized programs for further study and treatment if needed.
Keywords	hepatitis B ; prisons ; immigration ; vaccination ; epidemiology ; public health ; Medicine ; R ; Public aspects of medicine ; RA1-1270
Language	English
Publishing date	2024-01-01T00:00:00Z
Publisher	Sociedad Española de Sanidad Penitenciaria
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Morbilidad metabólica en la población penitenciaria de Cataluña

Andrés Marco Mouriño / Jesús Rivera-Esteban / Salvador Augustin / Elisabet Turu Santigosa / Juan M. Pericàs

Atención Primaria, Vol 55, Iss 6, Pp 102620- (2023)

2023

Abstract: Resumen: Objetivo: Investigar la prevalencia de la morbilidad metabólica (MM) en población penitenciaria. Diseño: Estudio observacional, transversal y multicéntrico. Emplazamiento: Los 9 centros penitenciarios de Cataluña. Participantes: Reclusos que no ... ...

Abstract	Resumen: Objetivo: Investigar la prevalencia de la morbilidad metabólica (MM) en población penitenciaria. Diseño: Estudio observacional, transversal y multicéntrico. Emplazamiento: Los 9 centros penitenciarios de Cataluña. Participantes: Reclusos que no están en «régimen abierto» y, por consiguiente, dependen sanitariamente de los equipos de atención primaria penitenciaria (EAPP). Intervenciones: Se consideraron internos con MM los que presentaban al menos un componente del síndrome metabólico: obesidad, hipertensión arterial, diabetes tipo 2 y/o dislipidemia. Se estudiaron variables antropométricas, antecedentes clínicos y parámetros analíticos asociados a la MM. Fuente de información: Sistema de Información de los Servicios de Atención Primaria de Cataluña (SISAP). Mediciones principales: Cálculo de prevalencia de la MM, total y por categorías. Para estudiar variables asociadas se realizó un análisis de regresión logística multivariante, calculándose la odds ratio ajustada (ORA) con intervalo de confianza del 95%. Resultados: Un total de 4.338 internos estudiados: el 93,9% hombres, edad media 38,4 años, 51,7% de la Unión Europea y 6,7% (8,2% de los analizados) infectados por VIH. Presentaron más MM los de más edad y las personas infectadas por VIH y menos los europeos de países no miembros de la Unión Europea, los del Magreb y los del África subsahariana. Conclusiones: La prevalencia de MM es alta en presos, aun siendo una población joven, especialmente en reclusos de mayor edad y en infectados por VIH. La prevalencia varía mucho según el origen geográfico. Es conveniente que la MM sea detectada precozmente para evitar complicaciones. La prevención, la detección y el manejo terapéutico deben ser actividades prioritarias de la atención primaria penitenciaria. Abstract: Objective: To investigate the prevalence of metabolic morbidity (MM) amongst prison inmates. Design: Multicentric, cross-sectional observational study. Setting: All (nine) prisons in Catalonia. Participants: Convicted inmates that are not in an ...
Keywords	Metabolic syndrome ; Non-communicable diseases ; Epidemiology ; Prisons ; Medicine (General) ; R5-920
Language	Spanish
Publishing date	2023-06-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Evolución de la mortalidad en población reclusa tras la introducción del tratamiento antirretroviral de gran actividad (TARGA)

Andrés Marco

Revista Española de Salud Pública, Vol 85, Iss 3, Pp 233-

2011 Volume 236

Keywords	Medicine ; R ; Public aspects of medicine ; RA1-1270
Language	English
Publishing date	2011-01-01T00:00:00Z
Publisher	Ministerio de Sanidad y Consumo
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Assessing kidney development and disease using kidney organoids and CRISPR engineering

Wajima Safi / Andrés Marco / Daniel Moya / Patricia Prado / Elena Garreta / Nuria Montserrat

Frontiers in Cell and Developmental Biology, Vol

2022 Volume 10

Abstract: The differentiation of human pluripotent stem cells (hPSCs) towards organoids is one of the biggest scientific advances in regenerative medicine. Kidney organoids have not only laid the groundwork for various organ-like tissue systems but also provided ... ...

Abstract	The differentiation of human pluripotent stem cells (hPSCs) towards organoids is one of the biggest scientific advances in regenerative medicine. Kidney organoids have not only laid the groundwork for various organ-like tissue systems but also provided insights into kidney embryonic development. Thus, several protocols for the differentiation of renal progenitors or mature cell types have been established. Insights into the interplay of developmental pathways in nephrogenesis and determination of different cell fates have enabled the in vitro recapitulation of nephrogenesis. Here we first provide an overview of kidney morphogenesis and patterning in the mouse model in order to dissect signalling pathways that are key to define culture conditions sustaining renal differentiation from hPSCs. Secondly, we also highlight how genome editing approaches have provided insights on the specific role of different genes and molecular pathways during renal differentiation from hPSCs. Based on this knowledge we further review how CRISPR/Cas9 technology has enabled the recapitulation and correction of cellular phenotypes associated with human renal disease. Last, we also revise how the field has positively benefited from emerging technologies as single cell RNA sequencing and discuss current limitations on kidney organoid technology that will take advantage from bioengineering solutions to help standardizing the use of this model systems to study kidney development and disease.
Keywords	pluripotent stem cells ; CRISPR ; nephrogenesis ; kidney engineering ; kidney organoids ; Biology (General) ; QH301-705.5
Subject code	616
Language	English
Publishing date	2022-09-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Incidence and molecular epidemiology of hepatitis C virus reinfection in prisons in Catalonia, Spain (Re-HCV study)

Verónica Saludes / Antoni E. Bordoy / Elena Yela / Elisabet Turú / Anna Not / Evelin López-Corbeto / Laia Egea-Cortés / Fernando González-Candelas / Jordi Casabona / Andrés Marco / Elisa Martró

Scientific Reports, Vol 13, Iss 1, Pp 1-

2023 Volume 11

Abstract: Abstract Hepatitis C virus (HCV) reinfection may hamper HCV elimination in prisons. We aimed to (i) determine the reinfection rate in people treated for HCV in Catalan prisons, (ii) measure reinfection in people entering prisons, and (iii) characterize ... ...

Abstract	Abstract Hepatitis C virus (HCV) reinfection may hamper HCV elimination in prisons. We aimed to (i) determine the reinfection rate in people treated for HCV in Catalan prisons, (ii) measure reinfection in people entering prisons, and (iii) characterize the molecular epidemiology of HCV in prisons and people who inject drugs (PWID) in the community. Re-HCV was a prospective study in eight prisons (2019–2020) including two groups: (1) people cured with treatment in prison and followed-up every 6 months, and (2) people testing HCV-RNA positive at incarceration. Bio-behavioral data were collected. HCV isolates were sequenced and phylogenetically analyzed with those of PWID in the community. Reinfection follow-up after treatment was achieved in 97 individuals (103.05 person-years). Two reinfections were detected, resulting in an incidence ≤ 10/100 person-years. Among people entering prison, 2% (359/17,732) were viremic, of which 334 (93.0%) were included, and 44 (13.5%) presented with reinfection (84.7% being PWID). Frequently, HCV isolates in prisons and PWID in the community were phylogenetically related. Although HCV reinfection is low after treatment, it is common in people entering Catalan prisons. To maintain a low HCV prevalence in prisons, harm-reduction services and test-and-treat programs for PWID should be strengthened both inside and outside prisons.
Keywords	Medicine ; R ; Science ; Q
Subject code	360
Language	English
Publishing date	2023-09-01T00:00:00Z
Publisher	Nature Portfolio
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Prevalence and Risk Factors of MASLD and Liver Fibrosis amongst the Penitentiary Population in Catalonia

Jesús Rivera-Esteban / Alba Jiménez-Masip / Sergio Muñoz-Martínez / Salvador Augustin / Rafael A. Guerrero / Pablo Gabriel-Medina / Roser Ferrer-Costa / Francisco Rodríguez-Frías / Elisabet Turu / Andrés Marco / Juan M. Pericàs

Journal of Clinical Medicine, Vol 12, Iss 23, p

The PRISONAFLD Study

2023 Volume 7276

Abstract: Background and Aims: The prevalence of chronic non-communicable diseases, particularly metabolic syndrome (MetS), has increased among the prison population. Nevertheless, we have limited data on metabolic dysfunction-associated steatotic liver disease ( ... ...

Abstract	Background and Aims: The prevalence of chronic non-communicable diseases, particularly metabolic syndrome (MetS), has increased among the prison population. Nevertheless, we have limited data on metabolic dysfunction-associated steatotic liver disease (MASLD), the hepatic manifestation of this syndrome. We aimed to investigate the prevalence and risk factors of MASLD and MASLD-associated liver fibrosis in the penitentiary population in Catalonia, Spain. Method: A cross-sectional observational study involving eight penitentiary centers. Participants had at least one metabolic disorder and were at a closed-regimen penitentiary. Individuals with concomitant liver diseases and/or alcohol risk consumption were excluded. Significant fibrosis and MASLD were defined as liver stiffness ≥8 kPa and a controlled attenuation parameter ≥275 dB/m by vibration-controlled transient elastography (VCTE), respectively. After exclusions, metabolic inmates with VCTE were analyzed. Logistic regression analysis was performed to identify predictors of MASLD and MASLD-associated significant fibrosis. Results: Out of the 4338 inmates studied, 1290 (29.7%) had metabolic disorders, and 646 (14.9%) underwent VCTE. The mean age was 48.0 years (SD 12.1), and 89.5% were male. MASLD prevalence was 33.9%. Significant fibrosis and MASLD-associated significant fibrosis were found in 16.4% and 9.4% of inmates, respectively. In the multivariate analysis, T2D, waist circumference, MetS, and higher ALT values were identified as independent risk factors for MASLD and MASLD-associated significant fibrosis amongst the prison population. Conclusions: Metabolic disorders including MASLD are highly prevalent among inmates. The prevalence of significant fibrosis seems notably higher than that of the general population, underscoring the need for targeted screening programs and therapeutic interventions in the incarcerated population.
Keywords	non-alcoholic fatty liver disease ; metabolic dysfunction-associated steatotic liver disease ; metabolic syndrome ; liver fibrosis ; prison ; Medicine ; R
Subject code	610
Language	English
Publishing date	2023-11-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Book ; Online: Schlussbericht zum Projekt "Dienstleistungsverkehr in industriellen Wertschöpfungsprozessen" für das Bundesminsterium für Wirtschaft und Technologie

Andres, Marco / Fromm, Michael

involvierte Arbeitspakete: AP 1, AP 3, AP 4, AP 5 ; [Teilvorhaben FTK: Untersuchung von Fallbeispielen] ; Laufzeit: 01.11.2004 - 30.09.2007

2008

Title variant	Dienstleistungsverkehr in industriellen Wertschöpfungsprozessen ; Final report on the project "Service traffic in industrial value-added processes"
Author's details	[Autoren des Berichts: Andres, Marco; Fromm, Michael]
Language	German
Size	Online-Ressource (65 S., 965 KB), graph. Darst.
Publisher	Technische Informationsbibliothek u. Universitätsbibliothek ; FTK
Publishing place	Hannover ; Dortmund
Document type	Book ; Online
Note	Förderkennzeichen BMWi 19 G 4034 B [richtig] - BMWi 19 G 4034 A [falsch]. - Verbund-Nr. 01034788. - Engl. Titel: Final report on the project "Service traffic in industrial value-added processes" ; Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource können nicht ausgeschlossen werden
Database	Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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Article ; Online: Incidence of hepatitis C infection among prisoners by routine laboratory values during a 20-year period.

Andrés Marco / Carlos Gallego / Joan A Caylà

PLoS ONE, Vol 9, Iss 2, p e

2014 Volume 90560

Abstract: Background To estimate the incidence of Hepatitis C virus (HCV) and the predictive factors through repeated routine laboratory analyses. Methods An observational cohort study was carried out in Quatre Camins Prison, Barcelona. The study included subjects ...

Abstract	Background To estimate the incidence of Hepatitis C virus (HCV) and the predictive factors through repeated routine laboratory analyses. Methods An observational cohort study was carried out in Quatre Camins Prison, Barcelona. The study included subjects with an initial negative HCV result and routine laboratory analyses containing HCV serology from 1992 to 2011. The incidence of infection was calculated for the study population and for sub-groups by 100 person-years of follow-up (100 py). The predictive factors were determined through Kaplan-Meier curves and a Cox regression. Hazard ratios (HR) and 95% confidence intervals (CI) were calculated. Results A total of 2,377 prisoners were included with a median follow-up time of 1,540.9 days per patient. Among the total population, 117 HCV seroconversions were detected (incidence of 1.17/100 py). The incidence was higher between 1992 and 1995 (2.57/100 py), among cases with HIV co-infection (8.34/100 py) and among intravenous drug users (IDU) without methadone treatment (MT) during follow-up (6.66/100 py). The incidence rate of HCV seroconversion among cases with a history of IDU and current MT was 1.35/100 py, which is close to that of the total study population. The following variables had a positive predictive value for HCV infection: IDU (p<0.001; HR = 7,30; CI: 4.83-11.04), Spanish ethnicity (p = 0.009; HR = 2,03; CI: 1.93-3.44) and HIV infection (p = 0.015; HR = 1.97; CI: 1.14-3.39). Conclusion The incidence of HCV infection among prisoners was higher during the first part of the study and among IDU during the entire study period. Preventative programs should be directed toward this sub-group of the prison population.
Keywords	Medicine ; R ; Science ; Q
Subject code	360
Language	English
Publishing date	2014-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
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