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  1. Article ; Online: Are Spinocerebellar Tracts Responsible for Epiletogenic Activity Control?

    Andreani, Juan Carlos

    Neuromodulation : journal of the International Neuromodulation Society

    2016  Volume 19, Issue 8, Page(s) 901–902

    MeSH term(s) Epilepsy/therapy ; Humans ; Spinal Cord Stimulation/methods ; Spinocerebellar Tracts/physiology
    Language English
    Publishing date 2016-12-01
    Publishing country United States
    Document type Letter
    ZDB-ID 1500372-3
    ISSN 1525-1403 ; 1094-7159
    ISSN (online) 1525-1403
    ISSN 1094-7159
    DOI 10.1111/ner.12544
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5912: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Remarkable clinical improvement with bilateral globus pallidus internus deep brain stimulation in a case of Lesch-Nyhan disease: five-year follow-up.

    Piedimonte, Fabián / Andreani, Juan Carlos / Piedimonte, Leandro / Micheli, Federico / Graff, Pablo / Bacaro, Valeria

    Neuromodulation : journal of the International Neuromodulation Society

    2015  Volume 18, Issue 2, Page(s) 118–22; discussion 122

    Abstract: Objectives: Lesch-Nyhan disease (LND) is a hereditary disorder characterized by hyperuricemia, self-mutilation, developmental retardation, and movement disorders such as spasticity and dystonia. The lack of a precise understanding of the neurological ... ...

    Abstract Objectives: Lesch-Nyhan disease (LND) is a hereditary disorder characterized by hyperuricemia, self-mutilation, developmental retardation, and movement disorders such as spasticity and dystonia. The lack of a precise understanding of the neurological dysfunction has precluded the development of useful conservative therapies. We present our experience treating a LND patient by bilateral globus pallidus internus (GPi) deep brain stimulation (DBS) with improvement in dystonia symptoms and disappearance of self-injurious behavior.
    Methods: We present a 29-year-old patient characterized by generalized severe dystonia and self-injurious behavior, both refractory to conservative treatment. The patient underwent a GPi bilateral electrode implant for chronic stimulation. Symptoms were evaluated with the Burke-Fhan-Marsden Dystonia Rating Scale (BFMDRS) and Mean Disability Scale (MDS) preoperatively and during the five-year follow-up.
    Results: We observed a remarkable improvement in dystonia symptoms and complete disappearance of self-injurious behavior.
    Conclusions: This case supports the hypothesis that automutilation in LND might be related to dysfunction of the basal ganglia circuits and the idea that bilateral GPi-DBS is a safe and effective treatment modality for this condition.
    MeSH term(s) Adult ; Deep Brain Stimulation/methods ; Disability Evaluation ; Globus Pallidus/physiology ; Humans ; Lesch-Nyhan Syndrome/therapy ; Longitudinal Studies ; Magnetic Resonance Imaging ; Male
    Language English
    Publishing date 2015-01-21
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1500372-3
    ISSN 1525-1403 ; 1094-7159
    ISSN (online) 1525-1403
    ISSN 1094-7159
    DOI 10.1111/ner.12261
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5912: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article: Lateral cord stimulation decreases spastic electromyographic spreading: responses in a brain-damaged pig preparation.

    Andreani, Juan Carlos M / Guma, Cristina

    Neuromodulation : journal of the International Neuromodulation Society

    2003  Volume 11, Issue 3, Page(s) 202–207

    Abstract: Objective.  The aim of our work was to investigate whether lateral stimulation of the spinal cord, lateral cord stimulation (LCS), results in inhibition of the spastic phenomena of upper motor lesions in an animal model. Methods.  This study was ... ...

    Abstract Objective.  The aim of our work was to investigate whether lateral stimulation of the spinal cord, lateral cord stimulation (LCS), results in inhibition of the spastic phenomena of upper motor lesions in an animal model. Methods.  This study was conducted using an animal model consisting of surgically brain damaged pigs subjected to unilateral cortical and subcortical brain lesions. A double laminectomy at cervical (C3-C4) and lumbar (L3-L6) was performed, and spastic thresholds of abnormal electromyographic responses, disseminated to adjacent segments, facilitated by spinal liberation, and produced by extradural electrical stimulation of the fourth lumbar root, were measured before and after cervical stimulation of the LCS. The variable studied was the minimal amount of current of LCS necessary to abolish electromyographic responses in the L7 myotome, away from the stimulated L4 nerve root. Results.  Experiments in 12 animals showed a significant increase of threshold after LCS, with a marked posteffect, signaling a less abnormal threshold. Conclusions.  This experiment demonstrated that LCS produces threshold increases to abolish abnormally propagated electromyographic evoked responses induced by the electrical stimulation of the fourth lumbar root in pigs with experimental cortical and subcortical brain lesions.
    Language English
    Publishing date 2003-06-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1500372-3
    ISSN 1094-7159
    ISSN 1094-7159
    DOI 10.1111/j.1525-1403.2008.00167.x
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5912: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: New animal model to mimic spastic cerebral palsy: the brain-damaged pig preparation.

    Andreani, Juan Carlos M / Guma, Cristina

    Neuromodulation : journal of the International Neuromodulation Society

    2003  Volume 11, Issue 3, Page(s) 196–201

    Abstract: Objective.  Classically, a decerebrated animal by mesencephalic lesioning is considered the paradigm for experimental study of spasticity that accompanies cerebral palsy, but, the model does not actually correspond with anatomical and pathologic ... ...

    Abstract Objective.  Classically, a decerebrated animal by mesencephalic lesioning is considered the paradigm for experimental study of spasticity that accompanies cerebral palsy, but, the model does not actually correspond with anatomical and pathologic realities. Therefore, a new and novel animal model is needed. Our objective was to create a more adapted animal model to be used in neuromodulation and functional electrical stimulation research. Materials and Methods.  Our new model in pigs closely simulates cortical and subcortical lesions produced by perinatal anoxic brain damage, which is present in spastic cerebral palsy and other spastic conditions. Our surgical lesions were produced by means of resecting the rolandic and perirolandic areas (cortical lesion) and aspiration and coagulation of white matter and deep gray nuclei. This model results in anatomic and pathologic configurations that are similar to human spastic cerebral palsy. We physiologically tested our model both in the pre- and postoperative situations. After experimental stimulation in nonoperated animals to establish mean latencies for preoperative bilateral cervical motor-evoked potentials and to confirm the absence of abnormally propagated electromyographic activity, another group of animals were retested using the same experimental variables before and after creation of the surgical lesioning in cortical and subcortical pyramidal areas. Results.  Normal latencies and no propagated electromyographic responses were found in sham animals. There were significant differences found in both latencies for motor-evoked potentials and electromyographic propagated responses when compared to pre- and postoperative values, which signaled abnormal physiology. Conclusions.  This animal model presents anatomic similarities to lesions currently present in cerebral palsy and related diseases. The model also shows electrophysiologic differences that signal chronic brain damage. Therefore, this method is useful in research when spastic syndromes produced by upper motor lesions need to be modeled.
    Language English
    Publishing date 2003-06-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1500372-3
    ISSN 1094-7159
    ISSN 1094-7159
    DOI 10.1111/j.1525-1403.2008.00166.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5912: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Behavioral and motor improvement after deep brain stimulation of the globus pallidus externus in a case of Tourette's syndrome.

    Piedimonte, Fabián / Andreani, Juan Carlos M / Piedimonte, Leandro / Graff, Pablo / Bacaro, Valeria / Micheli, Federico / Vilela Filho, Osvaldo

    Neuromodulation : journal of the International Neuromodulation Society

    2012  Volume 16, Issue 1, Page(s) 55–8; discussion 58

    Abstract: Objectives: The objective of our paper is to show the partial decrease of therapeutic effect with battery exhaustion in a previously successfully treated patient with refractory Tourette's syndrome (TS).: Materials and methods: We present a 47-year- ... ...

    Abstract Objectives: The objective of our paper is to show the partial decrease of therapeutic effect with battery exhaustion in a previously successfully treated patient with refractory Tourette's syndrome (TS).
    Materials and methods: We present a 47-year-old patient diagnosed with TS based on the TS Study Group Criteria and Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. Surgery was considered based on refractoriness to conservative management. Presurgical evaluation included magnetic resonance imaging (MRI), positron emission tomography scan, and neuropsychologic, neurologic, and psychiatric tests utilizing Yale Brown Obsessive Compulsive Scale, Yale Global Tics Severity Scale, Hamilton Depression Rating Scale, Hamilton Anxiety Rating Scale, Global Assessment of Functioning Scale, and Mini-mental State Examination. Target coordinates were obtained from inversion recovery MRI. Quadripolar deep brain stimulation (DBS) electrodes were implanted bilaterally in the globus pallidus externus (GPe) and connected to the pulse generator in the same procedure. To determine the clinical response to DBS, the scores of the scales obtained preoperatively were compared with those obtained postoperatively.
    Results: No surgical complications were detected and according to the clinical scales the patient experienced a marked improvement of his symptoms, although he never showed obsessive-compulsive disorder components of any type. The battery was exhausted after two years with the subsequent significant partial loss of therapeutic effect.
    Conclusions: GPe seems to be a highly promising target of DBS for the treatment of medically refractory TS. After battery exhaustion, the patient experienced a marked partial decrease in the therapeutic effect, which confirms the beneficial action of this method.
    MeSH term(s) Deep Brain Stimulation/methods ; Globus Pallidus/surgery ; Humans ; Male ; Middle Aged ; Tourette Syndrome/therapy
    Language English
    Publishing date 2012-12-14
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1500372-3
    ISSN 1525-1403 ; 1094-7159
    ISSN (online) 1525-1403
    ISSN 1094-7159
    DOI 10.1111/j.1525-1403.2012.00526.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5912: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Anatomical and Anatomo–Radiological Basis of the Chronic Stimulation of the Sphenopalatine Ganglion for the Treatment of Cluster Headaches

    Piedimonte, Fabián / Larrarte, Guillermo Agustín / Andreani, Juan Carlos / Piedimonte, Leandro / Graff, Pablo / Barbosa, Nicolás / Azar Schreiner, Denise R.

    Revista Argentina de Anatomia Online, Vol 3, Iss 4, Pp 101-

    2012  Volume 108

    Abstract: The objective is to establish the anatomical relations and the characteristics of involved structures in relation with the pterygopalatine ganglion (sphenopalatine ganglion) in order to justify the different aspects of the tactics and techniques facing ... ...

    Abstract The objective is to establish the anatomical relations and the characteristics of involved structures in relation with the pterygopalatine ganglion (sphenopalatine ganglion) in order to justify the different aspects of the tactics and techniques facing the therapeutics of the painful syndromes of neurovegetative origin in the deep region of pterygopalatine fossa. Data base information, cadaveric material and also radiological studies during the interventions of sphenopalatal stimulation were used to establish the parameters needed to guarantee that the pterygopalatine ganglion (sphenopalatine ganglion) is included in the electrical field. The anatomical studies infer that electrodes placement in the more exact area defines the localization of the sphenopalatal ganglion and its branches presented better results in pain control of the treated patients. We have tried to document the anatomical basis that support the surgical technique for the treatment of cluster headache syndrome (justifying neurovegetative manifestations with nocturnal aggravation).
    Keywords pterygopalatine ganglion (sphenopalatine ganglion ) ; Cluster Headaches ; Chronic Stimulation ; Treatment ; Human anatomy ; QM1-695 ; Science ; Q ; DOAJ:Anatomy ; DOAJ:Biology ; DOAJ:Biology and Life Sciences
    Language Spanish
    Publishing date 2012-12-01T00:00:00Z
    Publisher Asociacion Argentina de Anatomia
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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