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  1. AU="Anetsberger, Daniel"
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  1. Article: Anatomie mit klinischen Bezügen – Teil 1 Inneres und äußeres Genitale

    Anetsberger, Daniel / Beckmann, Matthias W. / Gaß, Paul / Heindl, Felix

    Frauenheilkunde up2date

    2023  Volume 17, Issue 05, Page(s) 437–454

    Keywords Anatomie ; Gynäkologie ; Geburtshilfe ; Embryonalentwicklung
    Language German
    Publishing date 2023-10-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2272764-4
    ISSN 1611-650X ; 1439-3719
    ISSN (online) 1611-650X
    ISSN 1439-3719
    DOI 10.1055/a-1861-0460
    Database Thieme publisher's database

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  2. Book ; Online ; Thesis: Morphological and Immunohistochemical Characterization of Human Intrinsic Gastric Neurons

    Anetsberger, Daniel [Verfasser] / Brehmer, Axel [Akademischer Betreuer] / Brehmer, Axel [Gutachter] / Fester, Lars [Gutachter]

    2023  

    Author's details Daniel Anetsberger ; Gutachter: Axel Brehmer, Lars Fester ; Betreuer: Axel Brehmer
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language Multiple languages
    Publisher Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU)
    Publishing place Erlangen
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  3. Article ; Online: Morphological and Immunohistochemical Characterization of Human Intrinsic Gastric Neurons.

    Anetsberger, Daniel / Kürten, Stefanie / Jabari, Samir / Brehmer, Axel

    Cells, tissues, organs

    2019  Volume 206, Issue 4-5, Page(s) 183–195

    Abstract: Our knowledge about human gastric enteric neuron types is even more limited than that of human intestinal types. Here, we immunohistochemically stained wholemounts and sections of gastric specimens obtained from 18 tumor-resected patients. Myenteric ... ...

    Abstract Our knowledge about human gastric enteric neuron types is even more limited than that of human intestinal types. Here, we immunohistochemically stained wholemounts and sections of gastric specimens obtained from 18 tumor-resected patients. Myenteric wholemounts were labeled for choline acetyl transferase (ChAT), neuronal nitric oxide synthase (NOS), and the human neuronal protein HuC/D (as pan-neuronal marker for quantitative analysis) or alternatively for neurofilament (for morphological evaluation). ChAT-positive neurons outnumbered NOS-positive neurons (56 vs. 27%), and neurons negative for both markers accounted for 17%. Two larger groups of neurons (each between 12 and 14%) costained for ChAT and vasoactive intestinal peptide (VIP) or for NOS and VIP, respectively. Clear morphochemical correlation was found for uniaxonal stubby type I neurons (ChAT+; putative excitatory inter- or motor neurons), for uniaxonal spiny type I neurons (NOS+/VIP+; putative inhibitory motor or interneurons), and for multiaxonal type II neurons (ChAT+; putative afferent neurons; immunostaining of additional wholemounts revealed their coreactivity for somatostatin). Whereas these latter neuron types were already known from the human intestine, the morphology of gastric myenteric neurons coreactive for ChAT and VIP was newly described: they had numerous short, extremely thin dendrites and resembled, together with their cell bodies, a "hairy" head. In our sections, nerve fibers coreactive for ChAT and VIP were commonly found only in the mucosa. We suggest these myenteric ChAT+/VIP+/hairy neurons to be mucosal effector neurons. In contrast to myenteric neurons, the much less common submucosal neurons were not embedded in a continuous plexus and did not display any clear morphochemical phenotypes.
    Language English
    Publishing date 2019-06-21
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1468141-9
    ISSN 1422-6421 ; 1422-6405
    ISSN (online) 1422-6421
    ISSN 1422-6405
    DOI 10.1159/000500566
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  4. Article: Morphological and Immunohistochemical Characterization of Human Intrinsic Gastric Neurons

    Anetsberger, Daniel / Kürten, Stefanie / Jabari, Samir / Brehmer, Axel

    Cells Tissues Organs

    2019  Volume 206, Issue 4-5, Page(s) 183–195

    Abstract: Our knowledge about human gastric enteric neuron types is even more limited than that of human intestinal types. Here, we immunohistochemically stained wholemounts and sections of gastric specimens obtained from 18 tumor-resected patients. Myenteric ... ...

    Institution Institute of Anatomy and Cell Biology, Friedrich Alexander University Erlangen-Nürnberg (FAU), Erlangen, Germany
    Institute of Neuropathology, Friedrich Alexander University Erlangen-Nürnberg (FAU), Erlangen, Germany
    Abstract Our knowledge about human gastric enteric neuron types is even more limited than that of human intestinal types. Here, we immunohistochemically stained wholemounts and sections of gastric specimens obtained from 18 tumor-resected patients. Myenteric wholemounts were labeled for choline acetyl transferase (ChAT), neuronal nitric oxide synthase (NOS), and the human neuronal protein HuC/D (as pan­neuronal marker for quantitative analysis) or alternatively for neurofilament (for morphological evaluation). ChAT-positive neurons outnumbered NOS-positive neurons (56 vs. 27%), and neurons negative for both markers accounted for 17%. Two larger groups of neurons (each between 12 and 14%) costained for ChAT and vasoactive intestinal peptide (VIP) or for NOS and VIP, respectively. Clear morphochemical correlation was found for uniaxonal stubby type I neurons (ChAT+; putative excitatory inter- or motor neurons), for uniaxonal spiny type I neurons (NOS+/VIP+; putative inhibitory motor or interneurons), and for multiaxonal type II neurons (ChAT+; putative afferent neurons; immunostaining of additional wholemounts revealed their coreactivity for somatostatin). Whereas these latter neuron types were already known from the human intestine, the morphology of gastric myenteric neurons coreactive for ChAT and VIP was newly described: they had numerous short, extremely thin dendrites and resembled, together with their cell bodies, a “hairy” head. In our sections, nerve fibers coreactive for ChAT and VIP were commonly found only in the mucosa. We suggest these myenteric ChAT+/VIP+/hairy neurons to be mucosal effector neurons. In contrast to myenteric neurons, the much less common submucosal neurons were not embedded in a continuous plexus and did not display any clear morphochemical phenotypes.
    Keywords Chemical coding ; Enteric nervous system ; Innervation ; Morphology ; Neurons ; Stomach
    Language English
    Publishing date 2019-06-21
    Publisher S. Karger AG
    Publishing place Basel, Switzerland
    Document type Article
    Note Developmental Biology / Research Article
    ZDB-ID 1468141-9
    ISSN 1422-6421 ; 1422-6405
    ISSN (online) 1422-6421
    ISSN 1422-6405
    DOI 10.1159/000500566
    Database Karger publisher's database

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Ub I Zs.150: Show issues Location:
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