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  1. Book: Radiation oncology

    Cox, James D. / Ang, Kie Kian

    rationale, technique and results

    (Expert consult)

    2010  

    Author's details James D. Cox ; K. Kian Ang
    Series title Expert consult
    Keywords Neoplasms / radiotherapy ; Cancer--Radiotherapy
    Subject code 616.9940642
    Language English
    Size XII, 1072 S. : Ill., graph. Darst., 29 cm
    Edition 9. ed.
    Publisher Mosby Elsevier
    Publishing place Philadelphia, Pa
    Publishing country United States
    Document type Book
    Accompanying material Zugang zur Internetausgabe über Code
    HBZ-ID HT016141017
    ISBN 978-0-323-04971-9 ; 0-323-04971-0
    Database Catalogue ZB MED Medicine, Health

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  2. Book: Radiotherapy for head and neck cancers

    Ang, Kie Kian / Garden, Adam S.

    indications and techniques

    2006  

    Author's details K. Kian Ang ; Adam S. Garden
    Keywords Head and Neck Neoplasms / radiotherapy ; Radiotherapy / methods ; Head/Cancer/Radiotherapy ; Neck/Cancer/Radiotherapy
    Subject code 616.994910642
    Language English
    Size XI, 212 S. : zahlr. Ill.
    Edition 3. ed.
    Publisher Lippincott Williams & Wilkins
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    Note Includes bibliographical references and index. - Previous ed.: 2001
    HBZ-ID HT014532823
    ISBN 0-7817-6093-3 ; 978-0-7817-6093-5
    Database Catalogue ZB MED Medicine, Health

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  3. Book: Radiation oncology

    Cox, James D. / Ang, Kie Kian

    rationale, technique, results

    2003  

    Author's details James D. Cox ; K. Kian Ang
    Keywords Neoplasms / radiotherapy ; Cancer/Radiotherapy
    Subject code 616.9920642
    Language English
    Size XIV, 1036 S. : Ill., graph. Darst.
    Edition 8. ed.
    Publisher Mosby
    Publishing place St. Louis
    Publishing country United States
    Document type Book
    Old title 7. Aufl. u.d.T. Moss' radiation oncology
    HBZ-ID HT013575446
    ISBN 0-323-01258-2 ; 978-0-323-01258-4
    Database Catalogue ZB MED Medicine, Health

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  4. Book: Radiation therapy in pediatric oncology

    Ang, Kie Kian / Cassady, James Robert

    with 94 tables

    (Medical radiology)

    1994  

    Author's details contributors: K. K. Ang ... Ed. by J. Robert Cassady
    Series title Medical radiology
    Keywords Neoplasms / in infancy & childhood ; Neoplasms / radiotherapy ; Kind ; Krebs ; Strahlentherapie
    Subject Bestrahlung ; Radiotherapie ; Strahlenbehandlung ; Radioonkologie ; Carcinom ; Malignom ; Maligner Tumor ; Neoplasma ; Karzinom ; Bösartiger Tumor ; Krebserkrankung ; Kindheit ; Kindesalter ; Kindschaft ; Kinder
    Language English
    Size X, 388 S. : Ill., graph. Darst.
    Publisher Springer
    Publishing place Berlin u.a.
    Document type Book
    HBZ-ID HT006418000
    ISBN 3-540-54105-5 ; 0-387-54105-5 ; 978-3-540-54105-9 ; 978-0-387-54105-1
    Database Catalogue ZB MED Medicine, Health

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  5. Book: Innovations in radiation oncology

    Ang, Kie Kian / Withers, Hubert Rodney

    (Medical radiology)

    1988  

    Author's details contrib. K. K. Ang. Ed. by H. Rodney Withers
    Series title Medical radiology
    Keywords Krebs ; Strahlentherapie
    Subject Bestrahlung ; Radiotherapie ; Strahlenbehandlung ; Radioonkologie ; Carcinom ; Malignom ; Maligner Tumor ; Neoplasma ; Karzinom ; Bösartiger Tumor ; Krebserkrankung
    Size XVII, 329 S. : Ill., graph. Darst.
    Publisher Springer
    Publishing place Berlin u.a.
    Document type Book
    Note Literaturangaben
    HBZ-ID HT003131894
    ISBN 3-540-17818-X ; 0-387-17818-X ; 978-3-540-17818-7 ; 978-0-387-17818-9
    Database Catalogue ZB MED Medicine, Health

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  6. Book ; Conference proceedings: Zusatz- und Nachbehandlung des Mammakarzinoms

    Ang, Kie Kian / Jung, Hugo

    Symposium der Niederrheinisch-Westfälischen Gesellschaft für Gynäkologie und Geburtshilfe, Aachen, vom 3. bis 4. Juni 1978

    (Bücherei des Frauenarztes ; 9)

    1979  

    Institution Niederrheinisch-Westfälische Gesellschaft für Gynäkologie und Geburtshilfe
    Author's details hrsg. von Hugo Jung ... Mit Beitr. von K. K. Ang
    Series title Bücherei des Frauenarztes ; 9
    Collection
    Keywords BREAST NEOPLASMS / THERAPY ; POSTOPERATIVE CARE
    Language German
    Size VI, 136 S. ; 24 CM
    Publisher Enke
    Publishing place Stuttgart
    Document type Book ; Conference proceedings
    HBZ-ID HT001086909
    ISBN 3-432-90501-7 ; 978-3-432-90501-3
    Database Catalogue ZB MED Medicine, Health

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  7. Article ; Online: Human papillomavirus as a marker of the natural history and response to therapy of head and neck squamous cell carcinoma.

    Ang, Kie Kian / Sturgis, Erich M

    Seminars in radiation oncology

    2012  Volume 22, Issue 2, Page(s) 128–142

    Abstract: There has been a gradual change in the demographics of head and neck carcinoma. Although relatively uncommon, the incidence of oropharyngeal carcinoma has been increasing despite declining tobacco consumption and contrary to a diminishing incidence of ... ...

    Abstract There has been a gradual change in the demographics of head and neck carcinoma. Although relatively uncommon, the incidence of oropharyngeal carcinoma has been increasing despite declining tobacco consumption and contrary to a diminishing incidence of cancers at other head and neck sites. It is now clear that the incidence of human papillomavirus (HPV)-associated oropharyngeal cancers is rising, likely as a consequence of changing life styles and sexual behaviors. Many studies have contributed to understanding the characteristics of HPV-related oropharyngeal carcinoma, which usually presents as nonkeratinizing squamous cell carcinoma of low to intermediate T-category and affects middle-aged white men, having higher socioeconomic status and no or brief history of tobacco consumption. The diagnosis of this distinct neoplastic entity can be firmly established by a combination of p16 immunohistochemical and in situ hybridization assays. Compared with the traditional smoking-associated head and neck squamous cell carcinoma, HPV-related oropharyngeal carcinoma has a favorable natural history and responds better to treatment. Consequently, patients with this cancer have better long-term survival than those with HPV-unrelated head and neck squamous cell carcinoma (eg, 5-year overall survival rate of >80% versus ∼40% for patients with stage III-IV tumors), and hence they are more likely to experience chronic therapy-induced morbidity. Therefore, changes in evaluation, staging, and treatment are needed for this patient group. However, attempts to change the treatment for HPV-associated oropharyngeal carcinoma should take place in a closely monitored clinical trial setting. In this article, we summarize the epidemiology, diagnosis, and clinical behavior of HPV-associated oropharyngeal carcinoma, with emphasis on prognostic and biomarker discovery aspects, and discuss briefly the current thoughts on changing the treatment paradigms aimed at reducing morbidity while preserving the high tumor control probability through well-coordinated prospective trials.
    MeSH term(s) Alphapapillomavirus/isolation & purification ; Biomarkers, Tumor/analysis ; Carcinoma, Squamous Cell/diagnosis ; Carcinoma, Squamous Cell/epidemiology ; Carcinoma, Squamous Cell/therapy ; Carcinoma, Squamous Cell/virology ; Clinical Trials as Topic ; Disease Progression ; Female ; Humans ; Male ; Middle Aged ; Oropharyngeal Neoplasms/diagnosis ; Oropharyngeal Neoplasms/epidemiology ; Oropharyngeal Neoplasms/therapy ; Oropharyngeal Neoplasms/virology ; Papillomavirus Infections/complications ; Prognosis
    Chemical Substances Biomarkers, Tumor
    Language English
    Publishing date 2012-04
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1146999-7
    ISSN 1532-9461 ; 1053-4296
    ISSN (online) 1532-9461
    ISSN 1053-4296
    DOI 10.1016/j.semradonc.2011.12.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book: Radiotherapy for head and neck cancers

    Ang, Kie Kian / Kaanders, Johannes H. A. M. / Peters, Lester J.

    indications and techniques

    1994  

    Author's details K. Kian Ang ; Johannes H. A. M. Kaanders ; Lester J. Peters
    Keywords Head and Neck Neoplasms / radiotherapy ; Radiotherapy / methods ; Halsregion ; Krebs ; Strahlentherapie ; Kopfregion
    Subject Bestrahlung ; Radiotherapie ; Strahlenbehandlung ; Radioonkologie ; Carcinom ; Malignom ; Maligner Tumor ; Neoplasma ; Karzinom ; Bösartiger Tumor ; Krebserkrankung
    Language English
    Size X, 141 S. : zahlr. Ill.
    Edition 1. print
    Publisher Lea & Febiger
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT006301709
    ISBN 0-8121-1678-X ; 978-0-8121-1678-6
    Database Catalogue ZB MED Medicine, Health

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  9. Book: Current topics in clinical radiobiology of tumors

    Ang, Kie Kian / Beck-Bornholdt, Hans-Peter

    with 21 tables

    (Medical radiology)

    1993  

    Author's details contributors K. K. Ang ... Ed. by Hans-Peter Beck-Bornholdt
    Series title Medical radiology
    Keywords Radiobiology ; Neoplasms / radiotherapy ; Radiotherapy / methods ; Krebs ; Strahlenbiologie
    Subject Radiobiologie ; Strahlenwirkung ; Strahlenbiophysik ; Carcinom ; Malignom ; Maligner Tumor ; Neoplasma ; Karzinom ; Bösartiger Tumor ; Krebserkrankung
    Language English
    Size 152 S. : Ill., graph. Darst.
    Publisher Springer
    Publishing place Berlin u.a.
    Document type Book
    HBZ-ID HT005051821
    ISBN 3-540-56512-4 ; 0-387-56512-4 ; 978-3-540-56512-3 ; 978-0-387-56512-5
    Database Catalogue ZB MED Medicine, Health

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  10. Article ; Online: Targeted therapies for squamous cell carcinoma of the head and neck: current knowledge and future directions.

    Schmitz, Sandra / Ang, Kie Kian / Vermorken, Jan / Haddad, Robert / Suarez, Carlos / Wolf, Gregory T / Hamoir, Marc / Machiels, Jean-Pascal

    Cancer treatment reviews

    2013  Volume 40, Issue 3, Page(s) 390–404

    Abstract: Despite progress in the therapeutic management of patients with squamous cell carcinoma of the head and neck (SCCHN), the mortality rate of patients presenting with advanced disease remains high. One approach to improve treatment efficacy is to add novel ...

    Abstract Despite progress in the therapeutic management of patients with squamous cell carcinoma of the head and neck (SCCHN), the mortality rate of patients presenting with advanced disease remains high. One approach to improve treatment efficacy is to add novel molecular targeted agents to the classical treatment regimens. Monoclonal antibodies targeting the epidermal growth factor receptor (EGFR) have shown clinical benefits in palliative and curative settings. However, only a minority of patients presenting with recurrent or metastatic (R/M) SCCHN have meaningful tumor regression with these agents and virtually all who do develop acquired tumor resistance after a few months of treatment. For these reasons, other inhibitors of EGFR or molecules that interfere with known molecular pathways activated in SCCHN are of considerable interest, either as single agents or in combination with other treatment modalities. In this review, we discuss the different molecular therapeutic approaches explored in SCCHN. We also briefly outline new trial designs that could be used to accelerate the investigation of emerging therapeutic agents in this disease.
    MeSH term(s) Antibodies, Monoclonal, Humanized/therapeutic use ; Carcinoma, Squamous Cell/drug therapy ; Carcinoma, Squamous Cell/immunology ; ErbB Receptors/antagonists & inhibitors ; Head and Neck Neoplasms/drug therapy ; Head and Neck Neoplasms/immunology ; Humans ; Molecular Targeted Therapy/methods ; Squamous Cell Carcinoma of Head and Neck ; Treatment Outcome
    Chemical Substances Antibodies, Monoclonal, Humanized ; ErbB Receptors (EC 2.7.10.1)
    Language English
    Publishing date 2013-09-14
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 125102-8
    ISSN 1532-1967 ; 0305-7372
    ISSN (online) 1532-1967
    ISSN 0305-7372
    DOI 10.1016/j.ctrv.2013.09.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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