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  1. Article ; Online: Flowchart for non-invasive ventilation support in COVID-19 patients from a northern Italy Emergency Department.

    Privitera, Daniele / Angaroni, Laura / Capsoni, Nicolò / Forni, Elisa / Pierotti, Federico / Vincenti, Fabrizio / Bellone, Andrea

    Internal and emergency medicine

    2020  Volume 15, Issue 5, Page(s) 767–771

    Abstract: With the rapid pandemic spread of the novel coronavirus (SARS-CoV2), Emergency Departments of affected countries are facing an increasing number of patients presenting with hypoxemic respiratory failure due to coronavirus disease 2019 (COVID-19). ... ...

    Abstract With the rapid pandemic spread of the novel coronavirus (SARS-CoV2), Emergency Departments of affected countries are facing an increasing number of patients presenting with hypoxemic respiratory failure due to coronavirus disease 2019 (COVID-19). Providing mechanical support and endotracheal intubation can be challenging due to a number of patients larger than usual, often exceeding available resources. Considering the lack of recommendations available, we developed a flowchart to standardize the first approach to patients presenting to the Emergency Department with hypoxemic respiratory failure due to COVID-19.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/physiopathology ; Coronavirus Infections/therapy ; Emergency Service, Hospital ; Guidelines as Topic ; Humans ; Intubation, Intratracheal ; Italy/epidemiology ; Noninvasive Ventilation/methods ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/physiopathology ; Pneumonia, Viral/therapy ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-05-20
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2454173-4
    ISSN 1970-9366 ; 1828-0447
    ISSN (online) 1970-9366
    ISSN 1828-0447
    DOI 10.1007/s11739-020-02370-8
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  2. Article: Nursing evaluation during treatment with helmet continuous positive airway pressure in patients with respiratory failure due to COVID-19 pneumonia: A case series.

    Privitera, Daniele / Capsoni, Nicolò / Mazzone, Annamaria / Airoldi, Chiara / Angaroni, Laura / Pierotti, Federico / Rocca, Eugenia / Dal Molin, Alberto / Bellone, Andrea

    Australian critical care : official journal of the Confederation of Australian Critical Care Nurses

    2021  Volume 35, Issue 1, Page(s) 46–51

    Abstract: Background: During COVID-19 outbreak, with the increasing number of patients presenting with acute respiratory failure, a large use of non invasive positive pressure ventilation was done in the emergency departments and medical wards despite the lack of ...

    Abstract Background: During COVID-19 outbreak, with the increasing number of patients presenting with acute respiratory failure, a large use of non invasive positive pressure ventilation was done in the emergency departments and medical wards despite the lack of recommendations.
    Objectives: This study describes the clinical characteristics of patients presenting to the hospital with acute respiratory failure due to COVID-19 related pneumonia undergoing treatment with helmet continuous positive airway pressure (CPAP) with a strict nursing evaluation and monitoring.
    Methods: A case series study enrolling adult patients admitted to an emergency department of an Italian hospital with acute respiratory failure due to COVID-19 pneumonia from March 18th to April 18th, 2020, was conducted. Only patients who strictly followed a local CPAP protocol were enrolled.
    Results: A total of 52 patients were included in this study. Thirty-eight patients (73%) were judged eligible for endotracheal intubation (ETI). Eighteen (34.6%) were intubated. Sixteen (30.8%) patients died: seven (38.9%) and nine (26.5%) in the eligible-for-ETI and non eligible-for-ETI group, respectively. The median hospital length of stay was different in the ETI and non-ETI group: 26 days (interquartile range [IQR]: 16-37) vs 15 days [IQR 9-17] (p = 0.005). The median invasive mechanical ventilation time was 11 days [IQR 7-21] with an ICU length of stay of 14.5 days [IQR 10-28]. During the CPAP trial, among patients eligible for ETI variations over time for positive end-expiratory pressure (p = 0.003) and respiratory rate (p = 0.059) were found between intubated and non-intubated patients.
    Conclusions: A short closed monitored CPAP trial could be considered for acute respiratory failure due to COVID-19 pneumonia before considering ETI. A progressive positive end-expiratory pressure titration should target reduction in a patient's respiratory rate. More studies are needed to evaluate the efficacy and predictors of failure of CPAP and non-invasive positive pressure ventilation in patients with acute respiratory failure due to COVID-19 pneumonia.
    MeSH term(s) Adult ; COVID-19 ; Continuous Positive Airway Pressure ; Head Protective Devices ; Humans ; Respiratory Insufficiency/etiology ; Respiratory Insufficiency/therapy ; SARS-CoV-2
    Language English
    Publishing date 2021-10-23
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 1159493-7
    ISSN 1878-1721 ; 1036-7314
    ISSN (online) 1878-1721
    ISSN 1036-7314
    DOI 10.1016/j.aucc.2021.10.001
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  3. Article: Flowchart for non-invasive ventilation support in COVID-19 patients from a northern Italy Emergency Department

    Privitera, Daniele / Angaroni, Laura / Capsoni, Nicolò / Forni, Elisa / Pierotti, Federico / Vincenti, Fabrizio / Bellone, Andrea

    Intern Emerg Med

    Abstract: With the rapid pandemic spread of the novel coronavirus (SARS-CoV2), Emergency Departments of affected countries are facing an increasing number of patients presenting with hypoxemic respiratory failure due to coronavirus disease 2019 (COVID-19). ... ...

    Abstract With the rapid pandemic spread of the novel coronavirus (SARS-CoV2), Emergency Departments of affected countries are facing an increasing number of patients presenting with hypoxemic respiratory failure due to coronavirus disease 2019 (COVID-19). Providing mechanical support and endotracheal intubation can be challenging due to a number of patients larger than usual, often exceeding available resources. Considering the lack of recommendations available, we developed a flowchart to standardize the first approach to patients presenting to the Emergency Department with hypoxemic respiratory failure due to COVID-19.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #324289
    Database COVID19

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  4. Article ; Online: Flowchart for non-invasive ventilation support in COVID-19 patients from a northern Italy Emergency Department

    Privitera, Daniele / Angaroni, Laura / Capsoni, Nicolò / Forni, Elisa / Pierotti, Federico / Vincenti, Fabrizio / Bellone, Andrea

    Internal and Emergency Medicine

    2020  Volume 15, Issue 5, Page(s) 767–771

    Keywords Internal Medicine ; Emergency Medicine ; covid19
    Language English
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2454173-4
    ISSN 1970-9366 ; 1828-0447
    ISSN (online) 1970-9366
    ISSN 1828-0447
    DOI 10.1007/s11739-020-02370-8
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  5. Article ; Online: Clinical characteristics and respiratory support of 310 COVID-19 patients, diagnosed at the emergency room: a single-center retrospective study.

    Di Domenico, Sandro Luigi / Coen, Daniele / Bergamaschi, Marta / Albertini, Valentina / Ghezzi, Leonardo / Cazzaniga, Michela Maria / Tombini, Valeria / Colombo, Riccardo / Capsoni, Nicolò / Coen, Tommaso / Cazzola, Katia Barbara / Di Fiore, Marina / Angaroni, Laura / Strozzi, Marco Alberto

    Internal and emergency medicine

    2020  Volume 16, Issue 4, Page(s) 1051–1060

    Abstract: An ongoing outbreak of pneumonia associated with severe acute respiratory coronavirus 2 (SARS-CoV-2) occurred at the end of February 2020 in Lombardy, Italy. We analyzed data from a retrospective, single-center case series of 310 consecutive patients, ... ...

    Abstract An ongoing outbreak of pneumonia associated with severe acute respiratory coronavirus 2 (SARS-CoV-2) occurred at the end of February 2020 in Lombardy, Italy. We analyzed data from a retrospective, single-center case series of 310 consecutive patients, with confirmed SARS-CoV-2 infection, admitted to the emergency room. We aimed to describe the clinical course, treatment and outcome of a cohort of patients with COVID-19 pneumonia, with special attention to oxygen delivery and ventilator support. Throughout the study period, 310 consecutive patients, with confirmed SARS-CoV-2 infection, attended the Emergency Room (ER), of these, 34 were discharged home directly from the ER. Of the remaining 276 patients, the overall mortality was 30.4%: 7 patients died in the ER and 77 during hospitalization. With respect to oxygen delivery: 22 patients did not need any oxygen support (8.0%), 151 patients were treated with oxygen only (54.7%), and 49 (17.8%) were intubated. 90 patients (32.6%) were treated with CPAP (Continuous Positive Airway Pressure) or NIV (Non Invasive Ventilation); in this group, 27 patients had a Do Not Intubate (DNI) order and were treated with CPAP/NIV as an upper threshold therapy, showing high mortality rate (88.9%). Among the 63 patients treated with CPAP/NIV without DNI, NIV failure occurred in 36 patients (57.1%), with mortality rate of 47.2%. Twenty-seven (27) patients were treated with CPAP/NIV without needing mechanical ventilation and 26 were discharged alive (96.3%). The study documents the poor prognosis of patients with severe respiratory failure, although a considerable minority of patients treated with CPAP/NIV had a positive outcome.
    MeSH term(s) Adult ; Aged ; COVID-19/complications ; COVID-19/mortality ; COVID-19/therapy ; Emergency Service, Hospital ; Female ; Hospitalization ; Humans ; Italy ; Male ; Middle Aged ; Outcome Assessment, Health Care ; Oxygen Inhalation Therapy ; Respiration, Artificial ; Retrospective Studies ; Survival Rate
    Keywords covid19
    Language English
    Publishing date 2020-11-11
    Publishing country Italy
    Document type Journal Article ; Observational Study
    ZDB-ID 2454173-4
    ISSN 1970-9366 ; 1828-0447
    ISSN (online) 1970-9366
    ISSN 1828-0447
    DOI 10.1007/s11739-020-02548-0
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  6. Article: Clinical characteristics and respiratory support of 310 COVID-19 patients, diagnosed at the emergency room: a single-center retrospective study

    Di Domenico, Sandro Luigi / Coen, Daniele / Bergamaschi, Marta / Albertini, Valentina / Ghezzi, Leonardo / Cazzaniga, Michela Maria / Tombini, Valeria / Colombo, Riccardo / Capsoni, Nicolò / Coen, Tommaso / Cazzola, Katia Barbara / Di Fiore, Marina / Angaroni, Laura / Strozzi, Marco Alberto

    Intern. emerg. med

    Abstract: An ongoing outbreak of pneumonia associated with severe acute respiratory coronavirus 2 (SARS-CoV-2) occurred at the end of February 2020 in Lombardy, Italy. We analyzed data from a retrospective, single-center case series of 310 consecutive patients, ... ...

    Abstract An ongoing outbreak of pneumonia associated with severe acute respiratory coronavirus 2 (SARS-CoV-2) occurred at the end of February 2020 in Lombardy, Italy. We analyzed data from a retrospective, single-center case series of 310 consecutive patients, with confirmed SARS-CoV-2 infection, admitted to the emergency room. We aimed to describe the clinical course, treatment and outcome of a cohort of patients with COVID-19 pneumonia, with special attention to oxygen delivery and ventilator support. Throughout the study period, 310 consecutive patients, with confirmed SARS-CoV-2 infection, attended the Emergency Room (ER), of these, 34 were discharged home directly from the ER. Of the remaining 276 patients, the overall mortality was 30.4%: 7 patients died in the ER and 77 during hospitalization. With respect to oxygen delivery: 22 patients did not need any oxygen support (8.0%), 151 patients were treated with oxygen only (54.7%), and 49 (17.8%) were intubated. 90 patients (32.6%) were treated with CPAP (Continuous Positive Airway Pressure) or NIV (Non Invasive Ventilation); in this group, 27 patients had a Do Not Intubate (DNI) order and were treated with CPAP/NIV as an upper threshold therapy, showing high mortality rate (88.9%). Among the 63 patients treated with CPAP/NIV without DNI, NIV failure occurred in 36 patients (57.1%), with mortality rate of 47.2%. Twenty-seven (27) patients were treated with CPAP/NIV without needing mechanical ventilation and 26 were discharged alive (96.3%). The study documents the poor prognosis of patients with severe respiratory failure, although a considerable minority of patients treated with CPAP/NIV had a positive outcome.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #919765
    Database COVID19

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  7. Article ; Online: A case of chest pain and heart failure.

    Scannella, Emanuela / Angaroni, Laura / Coerezza, Anna / Solbiati, Monica / Foieni, Fabrizio / Montano, Nicola

    Internal and emergency medicine

    2011  Volume 7, Issue 3, Page(s) 267–269

    MeSH term(s) Adrenergic beta-Antagonists/therapeutic use ; Angiotensin-Converting Enzyme Inhibitors/therapeutic use ; Cardiomyopathies/diagnosis ; Cardiomyopathies/drug therapy ; Cardiomyopathies/pathology ; Chest Pain/diagnosis ; Chest Pain/drug therapy ; Chest Pain/pathology ; Glucocorticoids/therapeutic use ; Heart Failure/diagnosis ; Heart Failure/drug therapy ; Heart Failure/pathology ; Humans ; Male ; Middle Aged ; Sarcoidosis/diagnosis ; Sarcoidosis/drug therapy ; Sarcoidosis/pathology
    Chemical Substances Adrenergic beta-Antagonists ; Angiotensin-Converting Enzyme Inhibitors ; Glucocorticoids
    Language English
    Publishing date 2011-05-06
    Publishing country Italy
    Document type Case Reports ; Journal Article
    ZDB-ID 2454173-4
    ISSN 1970-9366 ; 1828-0447
    ISSN (online) 1970-9366
    ISSN 1828-0447
    DOI 10.1007/s11739-011-0595-6
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  8. Article ; Online: Predictors of hospital admission after syncope: relationships with clinical risk scores.

    Perego, Francesca / Costantino, Giorgio / Dipaola, Franca / Scannella, Emanuela / Borella, Marta / Galli, Andrea / Barbic, Franca / Casella, Francesco / Solbiati, Monica / Angaroni, Laura / Duca, Piergiorgio / Furlan, Raffaello

    International journal of cardiology

    2012  Volume 161, Issue 3, Page(s) 182–183

    MeSH term(s) Adolescent ; Adult ; Age Factors ; Aged ; Electrocardiography/trends ; Female ; Hospitalization/trends ; Humans ; Male ; Middle Aged ; Patient Admission/trends ; Predictive Value of Tests ; Risk Factors ; Syncope/diagnosis ; Syncope/physiopathology ; Young Adult
    Language English
    Publishing date 2012-11-29
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 779519-1
    ISSN 1874-1754 ; 0167-5273
    ISSN (online) 1874-1754
    ISSN 0167-5273
    DOI 10.1016/j.ijcard.2012.06.061
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