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  1. Article: Angioödeme ohne Urtikaria: Anamnese und Befunde.

    Badini, Matteo / Georgitsogiannakos, Nikolaos / Angelella, Jennifer / Wu, Maddalena Alessandra

    Praxis

    2023  Volume 112, Issue 4, Page(s) 223–225

    Abstract: Angioedema without Urticaria: Medical History and ... ...

    Title translation Angioedema without Urticaria: Medical History and Findings.
    Abstract Angioedema without Urticaria: Medical History and Findings
    MeSH term(s) Female ; Humans ; Angioedema/diagnosis ; Angioedema/drug therapy ; Angioedema/etiology ; Urticaria/diagnosis ; Urticaria/drug therapy ; Urticaria/etiology ; Bradykinin/therapeutic use
    Chemical Substances Bradykinin (S8TIM42R2W)
    Language German
    Publishing date 2023-03-08
    Publishing country Switzerland
    Document type Case Reports ; English Abstract ; Journal Article
    ZDB-ID 209026-0
    ISSN 1661-8165 ; 1661-8157 ; 0369-8394
    ISSN (online) 1661-8165
    ISSN 1661-8157 ; 0369-8394
    DOI 10.1024/1661-8157/a003995
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.118: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 12: Show issues

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  2. Article ; Online: Apical closure device for full-percutaneous transapical valve implantation: stress-test in an animal model†.

    Ferrari, Enrico / Demertzis, Stefanos / Angelella, Jennifer / Berdajs, Denis / Tozzi, Piergiorgio / Moccetti, Tiziano / Maisano, Francesco / von Segesser, Ludwig K

    Interactive cardiovascular and thoracic surgery

    2017  Volume 24, Issue 5, Page(s) 721–726

    Abstract: Objectives: Transapical valve implantation is traditionally performed through a left antero-lateral mini-thoracotomy. A self-expandable apical closure device has recently been developed for full-percutaneous transapical valve implantation. We performed ... ...

    Abstract Objectives: Transapical valve implantation is traditionally performed through a left antero-lateral mini-thoracotomy. A self-expandable apical closure device has recently been developed for full-percutaneous transapical valve implantation. We performed haemodynamics stress-tests on an animal model to evaluate the sealing properties.
    Methods: Under general anaesthesia 5 pigs (mean weight: 67 ± 6 Kg) received full heparinization (100 IU/Kg; activated clotting time >250 s and, through inferior mini-sternotomies, 21-Fr introducer sheaths for transapical aortic valve implantation (outer diameter: 25-Fr) were placed over-the-wire in the apexes. Delivery-catheters carrying folded occluders (SAFEX TM final design) were inserted in the introducer sheaths and plugs were then deployed under fluoroscopic guidance. Phase 1: after protamine injection, apical bleeding was monitored for 1 h with standard haemodynamics condition. Phase 2: we induced systemic hypertension with adrenaline infusion to test the sealing properties under stress. Animals were sacrificed after Phase 2 and hearts were removed and inspected.
    Results: Five plugs were successfully introduced and deployed in 5 pig hearts. Plugs provided good apical sealing in each animal and a mean of 7 ± 4 ml of blood lost per animal was collected during Phase 1: haemodynamics remained stable and no plug dislodgement was detected (mean blood pressure: 52 ± 9 mmHg). During Phase 2, mean systolic and diastolic peak levels reached 268 ± 24 mmHg and 175 ± 17 mmHg, respectively, without plug dislodgment or bleeding. Post-mortem inspection showed good plug deployment and fixation without myocardial damage.
    Conclusions: The new apical occluder seals large-sized apical access sites in animal models also during induced systemic hypertension. This pilot study is a further step towards full-percutaneous transapical valve procedures in the clinical setting.
    MeSH term(s) Animals ; Aortic Valve/surgery ; Cardiac Catheters ; Equipment Design ; Feasibility Studies ; Heart Valve Diseases/physiopathology ; Heart Valve Diseases/surgery ; Heart Valve Prosthesis Implantation/instrumentation ; Hemodynamics/physiology ; Mitral Valve/surgery ; Pilot Projects ; Swine ; Treatment Outcome
    Language English
    Publishing date 2017-05-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2095298-3
    ISSN 1569-9285 ; 1569-9293
    ISSN (online) 1569-9285
    ISSN 1569-9293
    DOI 10.1093/icvts/ivw433
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5730: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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